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Volumn 34, Issue 1, 2015, Pages 375-381

Quercetin-induced autophagy flux enhances TRAIL-mediated tumor cell death

Author keywords

Autophagy; Lung cancer; Quercetin; TRAIL

Indexed keywords

CASPASE 3; PROTEIN KINASE B; PROTEIN P62; QUERCETIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; ANTINEOPLASTIC AGENT; CHLOROQUINE; MAP1LC3B PROTEIN, HUMAN; MICROTUBULE ASSOCIATED PROTEIN; P62 PROTEIN, HUMAN; RNA BINDING PROTEIN; TNFSF10 PROTEIN, HUMAN;

EID: 84930012393     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2015.3991     Document Type: Article
Times cited : (53)

References (43)
  • 1
    • 77954620216 scopus 로고    scopus 로고
    • A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis
    • Baowen Q, Yulin Z, Xin W, Wenjing X, Hao Z, Zhizhi C, Xingmei D, Xia Z, Yuquan W and Lijuan C: A further investigation concerning correlation between anti-fibrotic effect of liposomal quercetin and inflammatory cytokines in pulmonary fibrosis. Eur J Pharmacol 642: 134-139, 2010.
    • (2010) Eur J Pharmacol , vol.642 , pp. 134-139
    • Baowen, Q.1    Yulin, Z.2    Xin, W.3    Wenjing, X.4    Hao, Z.5    Zhizhi, C.6    Xingmei, D.7    Xia, Z.8    Yuquan, W.9    Lijuan, C.10
  • 2
    • 43049176634 scopus 로고    scopus 로고
    • Health effects of quercetin: From antioxidant to nutraceutical
    • Boots AW, Haenen GR and Bast A: Health effects of quercetin: From antioxidant to nutraceutical. Eur J Pharmacol 585: 325-337, 2008.
    • (2008) Eur J Pharmacol , vol.585 , pp. 325-337
    • Boots, A.W.1    Haenen, G.R.2    Bast, A.3
  • 3
    • 84904328439 scopus 로고    scopus 로고
    • Quercetin alleviates high glucose-induced Schwann cell damage by autophagy
    • Qu L, Liang X, Gu B and Liu W: Quercetin alleviates high glucose-induced Schwann cell damage by autophagy. Neural Regen Res 9: 1195-1203, 2014.
    • (2014) Neural Regen Res , vol.9 , pp. 1195-1203
    • Qu, L.1    Liang, X.2    Gu, B.3    Liu, W.4
  • 4
    • 84893824463 scopus 로고    scopus 로고
    • Quercetin induces mitochondrial mediated apoptosis and protective autophagy in human glioblastoma U373MG cells
    • Kim H, Moon JY, Ahn KS and Cho SK: Quercetin induces mitochondrial mediated apoptosis and protective autophagy in human glioblastoma U373MG cells. Oxid Med Cell Longev 2013: 596496, 2013.
    • (2013) Oxid Med Cell Longev , vol.2013 , pp. 596496
    • Kim, H.1    Moon, J.Y.2    Ahn, K.S.3    Cho, S.K.4
  • 5
    • 84864213132 scopus 로고    scopus 로고
    • Role of autophagy in quercetin-induced apoptosis in human bladder carcinoma BIU-87 cells
    • in Chinese
    • Wei L, Liu JJ, Cao J, Du NC, Ji LN and Yang XL: Role of autophagy in quercetin-induced apoptosis in human bladder carcinoma BIU-87 cells. Zhonghua Zhong Liu Za Zhi 34: 414-418, 2012 (in Chinese).
    • (2012) Zhonghua Zhong Liu za Zhi , vol.34 , pp. 414-418
    • Wei, L.1    Liu, J.J.2    Cao, J.3    Du, N.C.4    Ji, L.N.5    Yang, X.L.6
  • 6
  • 7
    • 51349127271 scopus 로고    scopus 로고
    • Multitargeted cancer prevention by quercetin
    • Murakami A, Ashida H and Terao J: Multitargeted cancer prevention by quercetin. Cancer Lett 269: 315-325, 2008.
    • (2008) Cancer Lett , vol.269 , pp. 315-325
    • Murakami, A.1    Ashida, H.2    Terao, J.3
  • 8
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller H: Mechanisms and genes of cellular suicide. Science 267: 1445-1449, 1995.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 9
    • 0026698173 scopus 로고
    • Apoptosis induced by anticancer drugs
    • Hickman JA: Apoptosis induced by anticancer drugs. Cancer Metastasis Rev 11: 121-139, 1992.
    • (1992) Cancer Metastasis Rev , vol.11 , pp. 121-139
    • Hickman, J.A.1
  • 10
    • 0036463370 scopus 로고    scopus 로고
    • Apoptosis-based anticancer drugs
    • Zhang JY: Apoptosis-based anticancer drugs. Nat Rev Drug Discov 1: 101-102, 2002.
    • (2002) Nat Rev Drug Discov , vol.1 , pp. 101-102
    • Zhang, J.Y.1
  • 11
    • 0037418619 scopus 로고    scopus 로고
    • TRAIL-induced signalling and apoptosis
    • MacFarlane M: TRAIL-induced signalling and apoptosis. Toxicol Lett 139: 89-97, 2003.
    • (2003) Toxicol Lett , vol.139 , pp. 89-97
    • MacFarlane, M.1
  • 12
    • 0038309329 scopus 로고    scopus 로고
    • The molecular mechanism of autophagy
    • Wang CW and Klionsky DJ: The molecular mechanism of autophagy. Mol Med 9: 65-76, 2003.
    • (2003) Mol Med , vol.9 , pp. 65-76
    • Wang, C.W.1    Klionsky, D.J.2
  • 13
    • 78751556979 scopus 로고    scopus 로고
    • Autophagy as a therapeutic target in cancer
    • Chen N and Karantza V: Autophagy as a therapeutic target in cancer. Cancer Biol Ther 11: 157-168, 2011.
    • (2011) Cancer Biol Ther , vol.11 , pp. 157-168
    • Chen, N.1    Karantza, V.2
  • 14
    • 0442323561 scopus 로고    scopus 로고
    • Autophagy: In sickness and in health
    • Cuervo AM: Autophagy: In sickness and in health. Trends Cell Biol 14: 70-77, 2004.
    • (2004) Trends Cell Biol , vol.14 , pp. 70-77
    • Cuervo, A.M.1
  • 17
    • 4544385218 scopus 로고    scopus 로고
    • Autophagy: Many paths to the same end
    • Cuervo AM: Autophagy: Many paths to the same end. Mol Cell Biochem 263: 55-72, 2004.
    • (2004) Mol Cell Biochem , vol.263 , pp. 55-72
    • Cuervo, A.M.1
  • 18
    • 84874881784 scopus 로고    scopus 로고
    • Targeting autophagic pathways for cancer drug discovery
    • Liu B, Bao JK, Yang JM and Cheng Y: Targeting autophagic pathways for cancer drug discovery. Chin J Cancer 32: 113-120, 2013.
    • (2013) Chin J Cancer , vol.32 , pp. 113-120
    • Liu, B.1    Bao, J.K.2    Yang, J.M.3    Cheng, Y.4
  • 19
    • 35448981935 scopus 로고    scopus 로고
    • Autophagy: From phenomenology to molecular understanding in less than a decade
    • Klionsky DJ: Autophagy: From phenomenology to molecular understanding in less than a decade. Nat Rev Mol Cell Biol 8: 931-937, 2007.
    • (2007) Nat Rev Mol Cell Biol , vol.8 , pp. 931-937
    • Klionsky, D.J.1
  • 21
    • 84896970273 scopus 로고    scopus 로고
    • Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids
    • Sahani MH, Itakura E and Mizushima N: Expression of the autophagy substrate SQSTM1/p62 is restored during prolonged starvation depending on transcriptional upregulation and autophagy-derived amino acids. Autophagy 10: 431-441, 2014.
    • (2014) Autophagy , vol.10 , pp. 431-441
    • Sahani, M.H.1    Itakura, E.2    Mizushima, N.3
  • 22
    • 79959364986 scopus 로고    scopus 로고
    • Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: Association with sequestosome 1/p62
    • Myeku N and Figueiredo-Pereira ME: Dynamics of the degradation of ubiquitinated proteins by proteasomes and autophagy: Association with sequestosome 1/p62. J Biol Chem 286: 22426-22440, 2011.
    • (2011) J Biol Chem , vol.286 , pp. 22426-22440
    • Myeku, N.1    Figueiredo-Pereira, M.E.2
  • 25
    • 77956363593 scopus 로고    scopus 로고
    • Autophagic pathways as new targets for cancer drug development
    • Liu B, Cheng Y, Liu Q, Bao JK and Yang JM: Autophagic pathways as new targets for cancer drug development. Acta Pharmacol Sin 31: 1154-1164, 2010.
    • (2010) Acta Pharmacol Sin , vol.31 , pp. 1154-1164
    • Liu, B.1    Cheng, Y.2    Liu, Q.3    Bao, J.K.4    Yang, J.M.5
  • 26
    • 84890483189 scopus 로고    scopus 로고
    • Effect of embelin on TRAIL receptor 2 mAb-induced apoptosis of TRAIL-resistant A549 non-small cell lung cancer cells
    • Jiang L, Hao JL, Jin ML, Zhang YG and Wei P: Effect of embelin on TRAIL receptor 2 mAb-induced apoptosis of TRAIL-resistant A549 non-small cell lung cancer cells. Asian Pac J Cancer Prev 14: 6115-6120, 2013.
    • (2013) Asian Pac J Cancer Prev , vol.14 , pp. 6115-6120
    • Jiang, L.1    Hao, J.L.2    Jin, M.L.3    Zhang, Y.G.4    Wei, P.5
  • 29
    • 84878904455 scopus 로고    scopus 로고
    • Cell survival and metastasis regulation by Akt signaling in colorectal cancer
    • Agarwal E, Brattain MG and Chowdhury S: Cell survival and metastasis regulation by Akt signaling in colorectal cancer. Cell Signal 25: 1711-1719, 2013.
    • (2013) Cell Signal , vol.25 , pp. 1711-1719
    • Agarwal, E.1    Brattain, M.G.2    Chowdhury, S.3
  • 30
  • 31
    • 28544435485 scopus 로고    scopus 로고
    • Lysosomes and autophagy in cell death control
    • Kroemer G and Jäättelä M: Lysosomes and autophagy in cell death control. Nat Rev Cancer 5: 886-897, 2005.
    • (2005) Nat Rev Cancer , vol.5 , pp. 886-897
    • Kroemer, G.1    Jäättelä, M.2
  • 33
    • 82455172117 scopus 로고    scopus 로고
    • Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins
    • Matsumoto G, Wada K, Okuno M, Kurosawa M and Nukina N: Serine 403 phosphorylation of p62/SQSTM1 regulates selective autophagic clearance of ubiquitinated proteins. Mol Cell 44: 279-289, 2011.
    • (2011) Mol Cell , vol.44 , pp. 279-289
    • Matsumoto, G.1    Wada, K.2    Okuno, M.3    Kurosawa, M.4    Nukina, N.5
  • 34
    • 58649083936 scopus 로고    scopus 로고
    • Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression
    • Jeong JH, An JY, Kwon YT, Rhee JG and Lee YJ: Effects of low dose quercetin: Cancer cell-specific inhibition of cell cycle progression. J Cell Biochem 106: 73-82, 2009.
    • (2009) J Cell Biochem , vol.106 , pp. 73-82
    • Jeong, J.H.1    An, J.Y.2    Kwon, Y.T.3    Rhee, J.G.4    Lee, Y.J.5
  • 36
    • 74949090299 scopus 로고    scopus 로고
    • An overview of the molecular mechanism of autophagy
    • Yang Z and Klionsky DJ: An overview of the molecular mechanism of autophagy. Curr Top Microbiol Immunol 335: 1-32, 2009.
    • (2009) Curr Top Microbiol Immunol , vol.335 , pp. 1-32
    • Yang, Z.1    Klionsky, D.J.2
  • 37
    • 69949106925 scopus 로고    scopus 로고
    • The double-edged sword of autophagy modulation in cancer
    • White E and DiPaola RS: The double-edged sword of autophagy modulation in cancer. Clin Cancer Res 15: 5308-5316, 2009.
    • (2009) Clin Cancer Res , vol.15 , pp. 5308-5316
    • White, E.1    DiPaola, R.S.2
  • 38
    • 80052380331 scopus 로고    scopus 로고
    • Quercetin induces protective autophagy in gastric cancer cells: Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling
    • Wang K, Liu R, Li J, Mao J, Lei Y, Wu J, Zeng J, Zhang T, Wu H, Chen L, et al: Quercetin induces protective autophagy in gastric cancer cells: Involvement of Akt-mTOR- and hypoxia-induced factor 1α-mediated signaling. Autophagy 7: 966-978, 2011.
    • (2011) Autophagy , vol.7 , pp. 966-978
    • Wang, K.1    Liu, R.2    Li, J.3    Mao, J.4    Lei, Y.5    Wu, J.6    Zeng, J.7    Zhang, T.8    Wu, H.9    Chen, L.10
  • 40
    • 34547624687 scopus 로고    scopus 로고
    • A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells
    • Park KJ, Lee SH, Kim TI, Lee HW, Lee CH, Kim EH, Jang JY, Choi KS, Kwon MH and Kim YS: A human scFv antibody against TRAIL receptor 2 induces autophagic cell death in both TRAIL-sensitive and TRAIL-resistant cancer cells. Cancer Res 67: 7327-7334, 2007.
    • (2007) Cancer Res , vol.67 , pp. 7327-7334
    • Park, K.J.1    Lee, S.H.2    Kim, T.I.3    Lee, H.W.4    Lee, C.H.5    Kim, E.H.6    Jang, J.Y.7    Choi, K.S.8    Kwon, M.H.9    Kim, Y.S.10
  • 41
    • 46249107850 scopus 로고    scopus 로고
    • Protein kinase C epsilon confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53
    • Shankar E, Sivaprasad U and Basu A: Protein kinase C epsilon confers resistance of MCF-7 cells to TRAIL by Akt-dependent activation of Hdm2 and downregulation of p53. Oncogene 27: 3957-3966, 2008.
    • (2008) Oncogene , vol.27 , pp. 3957-3966
    • Shankar, E.1    Sivaprasad, U.2    Basu, A.3
  • 42
    • 12944333065 scopus 로고    scopus 로고
    • PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment
    • Zauli G, Sancilio S, Cataldi A, Sabatini N, Bosco D and Di Pietro R: PI-3K/Akt and NF-kappaB/IkappaBalpha pathways are activated in Jurkat T cells in response to TRAIL treatment. J Cell Physiol 202: 900-911, 2005.
    • (2005) J Cell Physiol , vol.202 , pp. 900-911
    • Zauli, G.1    Sancilio, S.2    Cataldi, A.3    Sabatini, N.4    Bosco, D.5    Di Pietro, R.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.