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Volumn 290, Issue 21, 2015, Pages 13372-13385

TRAF family member-associated NF-κB activator (TANK) inhibits genotoxic nuclear factor κB activation by facilitating deubiquitinase USP10-dependent deubiquitination of TRAF6 ligase

Author keywords

[No Author keywords available]

Indexed keywords

DNA; MOBILE SECURITY; TANKS (CONTAINERS);

EID: 84930010074     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.643767     Document Type: Article
Times cited : (82)

References (47)
  • 1
    • 84858726313 scopus 로고    scopus 로고
    • Regulation of cell death and autophagy by IKK and NF-κB: Critical mechanisms in immune function and cancer
    • Baldwin, A. S. (2012) Regulation of cell death and autophagy by IKK and NF-κB: critical mechanisms in immune function and cancer. Immunol. Rev. 246, 327-345
    • (2012) Immunol. Rev. , vol.246 , pp. 327-345
    • Baldwin, A.S.1
  • 2
    • 84858722471 scopus 로고    scopus 로고
    • DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out
    • McCool, K. W., and Miyamoto, S. (2012) DNA damage-dependent NF-κB activation: NEMO turns nuclear signaling inside out. Immunol. Rev. 246, 311-326
    • (2012) Immunol. Rev. , vol.246 , pp. 311-326
    • McCool, K.W.1    Miyamoto, S.2
  • 3
    • 0032508414 scopus 로고    scopus 로고
    • NF-κB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C. Y., Mayo, M. W., Korneluk, R. G., Goeddel, D. V., and Baldwin, A. S., Jr. (1998) NF-κB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science 281, 1680-1683
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 4
    • 16844366650 scopus 로고    scopus 로고
    • Nuclear factor-κB inhibitors as sensitizers to anticancer drugs
    • Nakanishi, C., and Toi, M. (2005) Nuclear factor-κB inhibitors as sensitizers to anticancer drugs. Nat Rev Cancer 5, 297-309
    • (2005) Nat Rev Cancer , vol.5 , pp. 297-309
    • Nakanishi, C.1    Toi, M.2
  • 5
    • 84862689246 scopus 로고    scopus 로고
    • DNA damage induces NF-κB-dependent microRNA-21 upregulation and promotes breast cancer cell invasion
    • Niu, J., Shi, Y., Tan, G., Yang, C. H., Fan, M., Pfeffer, L. M., and Wu, Z. H. (2012) DNA damage induces NF-κB-dependent microRNA-21 upregulation and promotes breast cancer cell invasion. J. Biol. Chem. 287, 21783-21795
    • (2012) J. Biol. Chem. , vol.287 , pp. 21783-21795
    • Niu, J.1    Shi, Y.2    Tan, G.3    Yang, C.H.4    Fan, M.5    Pfeffer, L.M.6    Wu, Z.H.7
  • 6
    • 84856641109 scopus 로고    scopus 로고
    • NF-κB, the first quarter-century: Remarkable progress and outstanding questions
    • Hayden, M. S., and Ghosh, S. (2012) NF-κB, the first quarter-century: remarkable progress and outstanding questions. Genes Dev. 26, 203-234
    • (2012) Genes Dev. , vol.26 , pp. 203-234
    • Hayden, M.S.1    Ghosh, S.2
  • 7
    • 80051987703 scopus 로고    scopus 로고
    • Crosstalk in NF-κB signaling pathways
    • Oeckinghaus, A., Hayden, M. S., and Ghosh, S. (2011) Crosstalk in NF-κB signaling pathways. Nat. Immunol. 12, 695-708
    • (2011) Nat. Immunol. , vol.12 , pp. 695-708
    • Oeckinghaus, A.1    Hayden, M.S.2    Ghosh, S.3
  • 8
    • 84894534156 scopus 로고    scopus 로고
    • The IκB kinase complex in NF-κB regulation and beyond
    • Hinz, M., and Scheidereit, C. (2014) The IκB kinase complex in NF-κB regulation and beyond. EMBO Rep. 15, 46-61
    • (2014) EMBO Rep. , vol.15 , pp. 46-61
    • Hinz, M.1    Scheidereit, C.2
  • 9
    • 0344305376 scopus 로고    scopus 로고
    • Sequential modification of NEMO/IKKγ by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress
    • Huang, T. T., Wuerzberger-Davis, S. M., Wu, Z. H., and Miyamoto, S. (2003) Sequential modification of NEMO/IKKγ by SUMO-1 and ubiquitin mediates NF-κB activation by genotoxic stress. Cell 115, 565-576
    • (2003) Cell , vol.115 , pp. 565-576
    • Huang, T.T.1    Wuerzberger-Davis, S.M.2    Wu, Z.H.3    Miyamoto, S.4
  • 10
    • 28944447430 scopus 로고    scopus 로고
    • PIDD mediates NF-κB activation in response to DNA damage
    • Janssens, S., Tinel, A., Lippens, S., and Tschopp, J. (2005) PIDD mediates NF-κB activation in response to DNA damage. Cell 123, 1079-1092
    • (2005) Cell , vol.123 , pp. 1079-1092
    • Janssens, S.1    Tinel, A.2    Lippens, S.3    Tschopp, J.4
  • 11
    • 33748188499 scopus 로고    scopus 로고
    • PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress
    • Mabb, A. M., Wuerzberger-Davis, S. M., and Miyamoto, S. (2006) PIASy mediates NEMO sumoylation and NF-κB activation in response to genotoxic stress. Nat. Cell Biol. 8, 986-993
    • (2006) Nat. Cell Biol. , vol.8 , pp. 986-993
    • Mabb, A.M.1    Wuerzberger-Davis, S.M.2    Miyamoto, S.3
  • 12
    • 70449102637 scopus 로고    scopus 로고
    • A nuclear poly(ADP-Ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation
    • Stilmann, M., Hinz, M., Arslan, S. C., Zimmer, A., Schreiber, V., and Scheidereit, C. (2009) A nuclear poly(ADP-Ribose)-dependent signalosome confers DNA damage-induced IκB kinase activation. Mol. Cell 36, 365-378
    • (2009) Mol. Cell , vol.36 , pp. 365-378
    • Stilmann, M.1    Hinz, M.2    Arslan, S.C.3    Zimmer, A.4    Schreiber, V.5    Scheidereit, C.6
  • 13
    • 62449084941 scopus 로고    scopus 로고
    • cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-κB Activation
    • Jin, H.-S., Lee, D.-H., Kim, D.-H., Chung, J.-H., Lee, S.-J., and Lee, T. H. (2009) cIAP1, cIAP2, and XIAP act cooperatively via nonredundant pathways to regulate genotoxic stress-induced nuclear factor-κB Activation. Cancer Res. 69, 1782-1791
    • (2009) Cancer Res. , vol.69 , pp. 1782-1791
    • Jin, H.-S.1    Lee, D.-H.2    Kim, D.-H.3    Chung, J.-H.4    Lee, S.-J.5    Lee, T.H.6
  • 14
    • 33644538632 scopus 로고    scopus 로고
    • Molecular linkage between the kinase ATM and NF-κB signaling in response to genotoxic stimuli
    • Wu, Z. H., Shi, Y., Tibbetts, R. S., and Miyamoto, S. (2006) Molecular linkage between the kinase ATM and NF-κB signaling in response to genotoxic stimuli. Science 311, 1141-1146
    • (2006) Science , vol.311 , pp. 1141-1146
    • Wu, Z.H.1    Shi, Y.2    Tibbetts, R.S.3    Miyamoto, S.4
  • 15
    • 77957333810 scopus 로고    scopus 로고
    • A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation
    • Hinz, M., Stilmann, M., Arslan, S. Ç., Khanna, K. K., Dittmar, G., and Scheidereit, C. (2010) A cytoplasmic ATM-TRAF6-cIAP1 module links nuclear DNA damage signaling to ubiquitin-mediated NF-κB activation. Mol. Cell 40, 63-74
    • (2010) Mol. Cell , vol.40 , pp. 63-74
    • Hinz, M.1    Stilmann, M.2    Arslan, S.Ç.3    Khanna, K.K.4    Dittmar, G.5    Scheidereit, C.6
  • 16
    • 77957374335 scopus 로고    scopus 로고
    • ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress
    • Wu, Z. H., Wong, E. T., Shi, Y., Niu, J., Chen, Z., Miyamoto, S., and Tergaonkar, V. (2010) ATM- and NEMO-dependent ELKS ubiquitination coordinates TAK1-mediated IKK activation in response to genotoxic stress. Mol. Cell 40, 75-86
    • (2010) Mol. Cell , vol.40 , pp. 75-86
    • Wu, Z.H.1    Wong, E.T.2    Shi, Y.3    Niu, J.4    Chen, Z.5    Miyamoto, S.6    Tergaonkar, V.7
  • 18
    • 80052692078 scopus 로고    scopus 로고
    • LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO
    • Niu, J., Shi, Y., Iwai, K., and Wu, Z.-H. (2011) LUBAC regulates NF-κB activation upon genotoxic stress by promoting linear ubiquitination of NEMO. EMBO J. 30, 3741-3753
    • (2011) EMBO J. , vol.30 , pp. 3741-3753
    • Niu, J.1    Shi, Y.2    Iwai, K.3    Wu, Z.-H.4
  • 19
    • 80051982064 scopus 로고    scopus 로고
    • Return to homeostasis: Downregulation of NF-κB responses
    • Ruland, J. (2011) Return to homeostasis: downregulation of NF-κB responses. Nat. Immunol. 12, 709-714
    • (2011) Nat. Immunol. , vol.12 , pp. 709-714
    • Ruland, J.1
  • 20
    • 79960468868 scopus 로고    scopus 로고
    • NF-κB induction of the SUMO protease SENP2: A negative feedback loop to attenuate cell survival response to genotoxic stress
    • Lee, M. H., Mabb, A. M., Gill, G. B., Yeh, E. T., and Miyamoto, S. (2011) NF-κB induction of the SUMO protease SENP2: a negative feedback loop to attenuate cell survival response to genotoxic stress. Mol. Cell 43, 180-191
    • (2011) Mol. Cell , vol.43 , pp. 180-191
    • Lee, M.H.1    Mabb, A.M.2    Gill, G.B.3    Yeh, E.T.4    Miyamoto, S.5
  • 21
    • 84890568965 scopus 로고    scopus 로고
    • USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO
    • Niu, J., Shi, Y., Xue, J., Miao, R., Huang, S., Wang, T., Wu, J., Fu, M., and Wu, Z. H. (2013) USP10 inhibits genotoxic NF-κB activation by MCPIP1-facilitated deubiquitination of NEMO. EMBO J. 32, 3206-3219
    • (2013) EMBO J. , vol.32 , pp. 3206-3219
    • Niu, J.1    Shi, Y.2    Xue, J.3    Miao, R.4    Huang, S.5    Wang, T.6    Wu, J.7    Fu, M.8    Wu, Z.H.9
  • 22
    • 0033485542 scopus 로고    scopus 로고
    • NF-κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase
    • Pomerantz, J. L., and Baltimore, D. (1999) NF-κB activation by a signaling complex containing TRAF2, TANK and TBK1, a novel IKK-related kinase. EMBO J. 18, 6694-6704
    • (1999) EMBO J. , vol.18 , pp. 6694-6704
    • Pomerantz, J.L.1    Baltimore, D.2
  • 24
    • 0029917841 scopus 로고    scopus 로고
    • TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-κB activation
    • Cheng, G., and Baltimore, D. (1996) TANK, a co-inducer with TRAF2 of TNF- and CD 40L-mediated NF-κB activation. Genes Dev. 10, 963-973
    • (1996) Genes Dev. , vol.10 , pp. 963-973
    • Cheng, G.1    Baltimore, D.2
  • 25
    • 0038363463 scopus 로고    scopus 로고
    • Triggering the interferon antiviral response through an IKK-related pathway
    • Sharma, S., tenOever, B. R., Grandvaux, N., Zhou, G. P., Lin, R., and Hiscott, J. (2003) Triggering the interferon antiviral response through an IKK-related pathway. Science 300, 1148-1151
    • (2003) Science , vol.300 , pp. 1148-1151
    • Sharma, S.1    TenOever, B.R.2    Grandvaux, N.3    Zhou, G.P.4    Lin, R.5    Hiscott, J.6
  • 27
    • 30544447047 scopus 로고    scopus 로고
    • Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response
    • Oganesyan, G., Saha, S. K., Guo, B., He, J. Q., Shahangian, A., Zarnegar, B., Perry, A., and Cheng, G. (2006) Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response. Nature 439, 208-211
    • (2006) Nature , vol.439 , pp. 208-211
    • Oganesyan, G.1    Saha, S.K.2    Guo, B.3    He, J.Q.4    Shahangian, A.5    Zarnegar, B.6    Perry, A.7    Cheng, G.8
  • 28
    • 69049086481 scopus 로고    scopus 로고
    • TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis
    • Kawagoe, T., Takeuchi, O., Takabatake, Y., Kato, H., Isaka, Y., Tsujimura, T., and Akira, S. (2009) TANK is a negative regulator of Toll-like receptor signaling and is critical for the prevention of autoimmune nephritis. Nat. Immunol. 10, 965-972
    • (2009) Nat. Immunol. , vol.10 , pp. 965-972
    • Kawagoe, T.1    Takeuchi, O.2    Takabatake, Y.3    Kato, H.4    Isaka, Y.5    Tsujimura, T.6    Akira, S.7
  • 29
    • 84865268664 scopus 로고    scopus 로고
    • TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation
    • Maruyama, K., Kawagoe, T., Kondo, T., Akira, S., and Takeuchi, O. (2012) TRAF family member-associated NF-κB activator (TANK) is a negative regulator of osteoclastogenesis and bone formation. J. Biol. Chem. 287, 29114-29124
    • (2012) J. Biol. Chem. , vol.287 , pp. 29114-29124
    • Maruyama, K.1    Kawagoe, T.2    Kondo, T.3    Akira, S.4    Takeuchi, O.5
  • 30
    • 34249058290 scopus 로고    scopus 로고
    • Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK
    • Guo, B., and Cheng, G. (2007) Modulation of the interferon antiviral response by the TBK1/IKKi adaptor protein TANK. J. Biol. Chem. 282, 11817-11826
    • (2007) J. Biol. Chem. , vol.282 , pp. 11817-11826
    • Guo, B.1    Cheng, G.2
  • 32
    • 47949129452 scopus 로고    scopus 로고
    • Induction of a pro-apoptotic ATM-NF-κB pathway and its repression by ATR in response to replication stress
    • Wu, Z. H., and Miyamoto, S. (2008) Induction of a pro-apoptotic ATM-NF-κB pathway and its repression by ATR in response to replication stress. EMBO J. 27, 1963-1973
    • (2008) EMBO J. , vol.27 , pp. 1963-1973
    • Wu, Z.H.1    Miyamoto, S.2
  • 33
    • 84866550126 scopus 로고    scopus 로고
    • NF-κB-dependent microRNA-125b upregulation promotes cell survival by targeting p38α upon UV radiation
    • Tan, G., Niu, J., Shi, Y., Ouyang, H., and Wu, Z.-H. (2012) NF-κB-dependent microRNA-125b upregulation promotes cell survival by targeting p38α upon UV radiation. J. Biol. Chem. 287, 33036-33047
    • (2012) J. Biol. Chem. , vol.287 , pp. 33036-33047
    • Tan, G.1    Niu, J.2    Shi, Y.3    Ouyang, H.4    Wu, Z.-H.5
  • 36
    • 80054774247 scopus 로고    scopus 로고
    • The TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling
    • Clark, K., Takeuchi, O., Akira, S., and Cohen, P. (2011) The TRAF-associated protein TANK facilitates cross-talk within the IκB kinase family during Toll-like receptor signaling. Proc. Natl. Acad. Sci. U.S.A. 108, 17093-17098
    • (2011) Proc. Natl. Acad. Sci. U.S.A. , vol.108 , pp. 17093-17098
    • Clark, K.1    Takeuchi, O.2    Akira, S.3    Cohen, P.4
  • 37
    • 0037020147 scopus 로고    scopus 로고
    • Association of the adaptor TANK with the I κ B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases
    • Chariot, A., Leonardi, A., Muller, J., Bonif, M., Brown, K., and Siebenlist, U. (2002) Association of the adaptor TANK with the I κ B kinase (IKK) regulator NEMO connects IKK complexes with IKK epsilon and TBK1 kinases. J. Biol. Chem. 277, 37029-37036
    • (2002) J. Biol. Chem. , vol.277 , pp. 37029-37036
    • Chariot, A.1    Leonardi, A.2    Muller, J.3    Bonif, M.4    Brown, K.5    Siebenlist, U.6
  • 39
    • 78650371990 scopus 로고    scopus 로고
    • MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling
    • Liang, J., Saad, Y., Lei, T., Wang, J., Qi, D., Yang, Q., Kolattukudy, P. E., and Fu, M. (2010) MCP-induced protein 1 deubiquitinates TRAF proteins and negatively regulates JNK and NF-κB signaling. J. Exp. Med. 207, 2959-2973
    • (2010) J. Exp. Med. , vol.207 , pp. 2959-2973
    • Liang, J.1    Saad, Y.2    Lei, T.3    Wang, J.4    Qi, D.5    Yang, Q.6    Kolattukudy, P.E.7    Fu, M.8
  • 40
    • 84878875514 scopus 로고    scopus 로고
    • When ubiquitin meets NF-κB: A trove for anti-cancer drug development
    • Wu, Z. H., and Shi, Y. (2013) When ubiquitin meets NF-κB: a trove for anti-cancer drug development. Curr. Pharm. Des. 19, 3263-3275
    • (2013) Curr. Pharm. Des. , vol.19 , pp. 3263-3275
    • Wu, Z.H.1    Shi, Y.2
  • 43
    • 67349231313 scopus 로고    scopus 로고
    • Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains
    • Komander, D., Reyes-Turcu, F., Licchesi, J. D., Odenwaelder, P., Wilkinson, K. D., and Barford, D. (2009) Molecular discrimination of structurally equivalent Lys 63-linked and linear polyubiquitin chains. EMBO Rep. 10, 466-473
    • (2009) EMBO Rep. , vol.10 , pp. 466-473
    • Komander, D.1    Reyes-Turcu, F.2    Licchesi, J.D.3    Odenwaelder, P.4    Wilkinson, K.D.5    Barford, D.6
  • 45
    • 75749132016 scopus 로고    scopus 로고
    • USP10 regulates p53 localization and stability by deubiquitinating p53
    • Yuan, J., Luo, K., Zhang, L., Cheville, J. C., and Lou, Z. (2010) USP10 regulates p53 localization and stability by deubiquitinating p53. Cell 140, 384-396
    • (2010) Cell , vol.140 , pp. 384-396
    • Yuan, J.1    Luo, K.2    Zhang, L.3    Cheville, J.C.4    Lou, Z.5
  • 47
    • 84890979013 scopus 로고    scopus 로고
    • USP10 Antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation
    • Lin, Z., Yang, H., Tan, C., Li, J., Liu, Z., Quan, Q., Kong, S., Ye, J., Gao, B., and Fang, D. (2013) USP10 Antagonizes c-Myc transcriptional activation through SIRT6 stabilization to suppress tumor formation. Cell Rep. 5, 1639-1649
    • (2013) Cell Rep. , vol.5 , pp. 1639-1649
    • Lin, Z.1    Yang, H.2    Tan, C.3    Li, J.4    Liu, Z.5    Quan, Q.6    Kong, S.7    Ye, J.8    Gao, B.9    Fang, D.10


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.