Upregulation of podocyte-secreted angiopoietin-like-4 in diabetic nephropathy

Endocrine

Volumn 49, Issue 2, 2015, Pages 373-384

  Ma, Jing ^a   Chen, Xiao ^a   Li, Jian Si ^a   Peng, Lei ^a   Wei, Shi Yao ^a   Zhao, Shi Lei ^a   Li, Tong ^a   Zhu, Dan ^a   He, Yi Xin ^a   Wei, Qiu Ju ^a   Li, Bing ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Albuminuria; Angiopoietin like 4; Diabetic nephropathy; Podocyte

Indexed keywords

ALBUMIN; ANGIOPOIETIN; ANGIOPOIETIN LIKE 4; CREATININE; SYNAPTOPODIN; UNCLASSIFIED DRUG; ACTIN BINDING PROTEIN; ANGPTL4 PROTEIN, RAT; ANTINEOPLASTIC ANTIBIOTIC; STREPTOZOCIN; SYNPO PROTEIN, RAT;

ALBUMINURIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DAMAGE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; DISEASE ASSOCIATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GLOMERULUS; GLOMERULUS BASEMENT MEMBRANE; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MAJOR CLINICAL STUDY; MALE; MOLECULAR PATHOLOGY; NONHUMAN; PODOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; PROTEIN TRANSPORT; PROTEIN URINE LEVEL; RAT; REAL TIME POLYMERASE CHAIN REACTION; UPREGULATION; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PATHOLOGY; SPRAGUE DAWLEY RAT;

ALBUMINURIA; ANGIOPOIETINS; ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC NEPHROPATHIES; GLOMERULAR BASEMENT MEMBRANE; HUMANS; MALE; MICROFILAMENT PROTEINS; PODOCYTES; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; UP-REGULATION;

EID: 84929960633     PISSN: 1355008X     EISSN: 15590100     Source Type: Journal    
DOI: 10.1007/s12020-014-0486-5     Document Type: Article

References (39)

1. R. Veelken, K.F. Hilgers, A. Hartner, A. Haas, K.P. Bohmer, R.B. Sterzel, Nitric oxide synthase isoforms and glomerular hyperfiltration in early diabetic nephropathy. J. Am. Soc. Nephrol. 11(1), 71–79 (2000)
2. Y. Yamamoto, I. Kato, T. Doi, H. Yonekura, S. Ohashi, M. Takeuchi, T. Watanabe, S. Yamagishi, S. Sakurai, S. Takasawa, H. Okamoto, H. Yamamoto, Development and prevention of advanced diabetic nephropathy in rage-overexpressing mice. J. Clin. Investig. 108(2), 261–268 (2001)
3. Standards of medical care in diabetes-2008, Diabetes care 31(Suppl 1), S12–54 (2008)
4. A.I. Adler, R.J. Stevens, S.E. Manley, R.W. Bilous, C.A. Cull, R.R. Holman, Development and progression of nephropathy in type 2 diabetes: the united kingdom prospective diabetes study (ukpds 64). Kidney Int. 63(1), 225–232 (2003)
5. T. Ninomiya, V. Perkovic, B.E. de Galan, S. Zoungas, A. Pillai, M. Jardine, A. Patel, A. Cass, B. Neal, N. Poulter, C.E. Mogensen, M. Cooper, M. Marre, B. Williams, P. Hamet, G. Mancia, M. Woodward, S. Macmahon, J. Chalmers, Albuminuria and kidney function independently predict cardiovascular and renal outcomes in diabetes. J. Am. Soc. Nephrol. 20(8), 1813–1821 (2009)
6. G. Gruden, P.C. Perin, G. Camussi, Insight on the pathogenesis of diabetic nephropathy from the study of podocyte and mesangial cell biology. Curr. Diabetes Rev. 1(1), 27–40 (2005)
7. J.A. Jefferson, S.J. Shankland, R.H. Pichler, Proteinuria in diabetic kidney disease: a mechanistic viewpoint. Kidney Int. 74(1), 22–36 (2008)
8. F.S. Siddiqi, A. Advani, Endothelial-podocyte crosstalk: the missing link between endothelial dysfunction and albuminuria in diabetes. Diabetes 62(11), 3647–3655 (2013)
9. D.P. Naidoo, The link between microalbuminuria, endothelial dysfunction and cardiovascular disease in diabetes, Cardiovasc. J. S. Afr. 13(4), 194–199 (2002)
10. H. Cheng, X. Fan, G.W. Moeckel, R.C. Harris, Podocyte cox-2 exacerbates diabetic nephropathy by increasing podocyte (pro)renin receptor expression. J. Am. Soc. Nephrol. 22(7), 1240–1251 (2011)
11. A.V. Cybulsky, T. Takano, J. Papillon, J. Guillemette, A.M. Herzenberg, C.R. Kennedy, Podocyte injury and albuminuria in mice with podocyte-specific overexpression of the ste20-like kinase, slk. Am. J. Pathol. 177(5), 2290–2299 (2010)
12. H. Zhang, M. Schin, J. Saha, K. Burke, L.B. Holzman, W. Filipiak, T. Saunders, M. Xiang, C.W. Heilig, F.C. Brosius 3rd, Podocyte-specific overexpression of glut1 surprisingly reduces mesangial matrix expansion in diabetic nephropathy in mice. Am. J. Physiol. 299(1), F91–F98 (2010)
13. Y. Oike, K. Yasunaga, T. Suda, Angiopoietin-related/angiopoietin-like proteins regulate angiogenesis. Int. J. Hematol. 80(1), 21–28 (2004)
14. Y. Kubota, Y. Oike, S. Satoh, Y. Tabata, Y. Niikura, T. Morisada, M. Akao, T. Urano, Y. Ito, T. Miyamoto, N. Nagai, G.Y. Koh, S. Watanabe, T. Suda, Cooperative interaction of angiopoietin-like proteins 1 and 2 in zebrafish vascular development. Proc. Natl. Acad. Sci. USA 102(38), 13502–13507 (2005)
15. A. Galaup, A. Cazes, S. Le Jan, J. Philippe, E. Connault, E. Le Coz, H. Mekid, L.M. Mir, P. Opolon, P. Corvol, C. Monnot, S. Germain, Angiopoietin-like 4 prevents metastasis through inhibition of vascular permeability and tumor cell motility and invasiveness. Proc. Natl. Acad. Sci. USA 103(49), 18721–18726 (2006)
16. S. Kersten, S. Mandard, N.S. Tan, P. Escher, D. Metzger, P. Chambon, F.J. Gonzalez, B. Desvergne, W. Wahli, Characterization of the fasting-induced adipose factor fiaf, a novel peroxisome proliferator-activated receptor target gene. J. Biol. Chem. 275(37), 28488–28493 (2000)
17. S. Mandard, F. Zandbergen, E. van Straten, W. Wahli, F. Kuipers, M. Muller, S. Kersten, The fasting-induced adipose factor/angiopoietin-like protein 4 is physically associated with lipoproteins and governs plasma lipid levels and adiposity. J. Biol. Chem. 281(2), 934–944 (2006)
18. J.C. Yoon, T.W. Chickering, E.D. Rosen, B. Dussault, Y. Qin, A. Soukas, J.M. Friedman, W.E. Holmes, B.M. Spiegelman, Peroxisome proliferator-activated receptor gamma target gene encoding a novel angiopoietin-related protein associated with adipose differentiation. Mol. Cell. Biol. 20(14), 5343–5349 (2000)
19. L.C. Clement, C. Avila-Casado, C. Mace, E. Soria, W.W. Bakker, S. Kersten, S.S. Chugh, Podocyte-secreted angiopoietin-like-4 mediates proteinuria in glucocorticoid-sensitive nephrotic syndrome. Nat. Med. 17(1), 117–122 (2011)
20. B. Li, A. Cohen, T.E. Hudson, D. Motlagh, D.L. Amrani, J.S. Duffield, Mobilized human hematopoietic stem/progenitor cells promote kidney repair after ischemia/reperfusion injury. Circulation 121(20), 2211–2220 (2010)
21. S.L. Lin, B. Li, S. Rao, E.J. Yeo, T.E. Hudson, B.T. Nowlin, H. Pei, L. Chen, J.J. Zheng, T.J. Carroll, J.W. Pollard, A.P. McMahon, R.A. Lang, J.S. Duffield, Macrophage wnt7b is critical for kidney repair and regeneration. Proc. Natl. Acad. Sci. USA 107(9), 4194–4199 (2010)
22. L. Peng, J. Ma, R. Cui, X. Chen, S.Y. Wei, Q.J. Wei, B. Li, The calcineurin inhibitor tacrolimus reduces proteinuria in membranous nephropathy accompanied by a decrease in angiopoietin-Like-4. Plos One 9(8), e106164 (2014)
23. T.D. Schmittgen, K.J. Livak, Analyzing real-time PCR data by the comparative C(T) method. Nat. Protoc. 3(6), 1101–1108 (2008)
24. E. Mandache, M. Penescu, Nanostructural features of diabetic podocytopathy. Rom. J. Morphol. Embryol. 53(1), 23–27 (2012)
25. J.J. Li, S.J. Kwak, D.S. Jung, J.J. Kim, T.H. Yoo, D.R. Ryu, S H. Han, H.Y. Choi, J.E. Lee, S.J. Moon, D.K. Kim, D.S. Han, S.W. Kang, Podocyte biology in diabetic nephropathy, Kidney Int. (Supplement no. 106), S36–42 (2007)
26. G. Wolf, F.N. Ziyadeh, Cellular and molecular mechanisms of proteinuria in diabetic nephropathy. Nephron. Physiol. 106(2), 26–31 (2007)
27. R.N. Moresco, M.B. Sangoi, J.A. De Carvalho, E. Tatsch, G.V. Bochi, Diabetic nephropathy: traditional to proteomic markers. Clin. Chim. Acta 421, 17–30 (2013)
28. S.J. Shankland, The podocyte’s response to injury: role in proteinuria and glomerulosclerosis. Kidney Int. 69(12), 2131–2147 (2006)
29. G. Wolf, S. Chen, F.N. Ziyadeh, From the periphery of the glomerular capillary wall toward the center of disease: podocyte injury comes of age in diabetic nephropathy. Diabetes 54(6), 1626–1634 (2005)
30. A. Georgiadi, L. Lichtenstein, T. Degenhardt, M.V. Boekschoten, M. van Bilsen, B. Desvergne, M. Muller, S. Kersten, Induction of cardiac angptl4 by dietary fatty acids is mediated by peroxisome proliferator-activated receptor beta/delta and protects against fatty acid-induced oxidative stress. Circ. Res. 106(11), 1712–1721 (2010)
31. A.M. Ordelheide, M. Heni, C. Thamer, F. Machicao, A. Fritsche, N. Stefan, H.U. Haring, H. Staiger, In vitro responsiveness of human muscle cell peroxisome proliferator-activated receptor delta reflects donors’ insulin sensitivity in vivo. Eur. J. Clin. Invest. 41(12), 1323–1329 (2011)
32. M.R. Robciuc, P. Skrobuk, A. Anisimov, V.M. Olkkonen, K. Alitalo, R.H. Eckel, H.A. Koistinen, M. Jauhiainen, C. Ehnholm, Angiopoietin-like 4 mediates ppar delta effect on lipoprotein lipase-dependent fatty acid uptake but not on beta-oxidation in myotubes, PloS one 7(10), e46212 (2012)
33. K. Yoshida, T. Shimizugawa, M. Ono, H. Furukawa, Angiopoietin-like protein 4 is a potent hyperlipidemia-inducing factor in mice and inhibitor of lipoprotein lipase, J. Lipid Res. 43(11), 1770–1772 (2002)
34. D. Padua, X.H. Zhang, Q. Wang, C. Nadal, W.L. Gerald, R.R. Gomis, J. Massague, Tgfbeta primes breast tumors for lung metastasis seeding through angiopoietin-like 4. Cell 133(1), 66–77 (2008)
35. S.H. Kim, Y.Y. Park, S.W. Kim, J.S. Lee, D. Wang, R.N. DuBois, Angptl4 induction by prostaglandin e2 under hypoxic conditions promotes colorectal cancer progression. Cancer Res. 71(22), 7010–7020 (2011)
36. Y.Y. Goh, M. Pal, H.C. Chong, P. Zhu, M.J. Tan, L. Punugu, C.K. Tan, R.L. Huang, S.K. Sze, M.B. Tang, J.L. Ding, S. Kersten, N.S. Tan, Angiopoietin-like 4 interacts with matrix proteins to modulate wound healing. J. Biol. Chem. 285(43), 32999–33009 (2010)
37. 2 ratio and confers anoikis resistance to tumors. Cancer Cell 19(3), 401–415 (2011)
38. M.C. Smart-Halajko, M.R. Robciuc, J.A. Cooper, M. Jauhiainen, M. Kumari, M. Kivimaki, K.T. Khaw, S.M. Boekholdt, N.J. Wareham, T.R. Gaunt, I.N. Day, P.S. Braund, C.P. Nelson, A.S. Hall, N.J. Samani, S.E. Humphries, C. Ehnholm, P.J. Talmud, The relationship between plasma angiopoietin-like protein 4 levels, angiopoietin-like protein 4 genotype, and coronary heart disease risk. Arterioscler. Thromb. Vasc. Biol. 30(11), 2277–2282 (2010)
39. A. Galaup, E. Gomez, R. Souktani, M. Durand, A. Cazes, C. Monnot, J. Teillon, S. Le Jan, C. Bouleti, G. Briois, J. Philippe, S. Pons, V. Martin, R. Assaly, P. Bonnin, P. Ratajczak, A. Janin, G. Thurston, D.M. Valenzuela, A.J. Murphy, G.D. Yancopoulos, R. Tissier, A. Berdeaux, B. Ghaleh, S. Germain, Protection against myocardial infarction and no-reflow through preservation of vascular integrity by angiopoietin-like 4. Circulation 125(1), 140–149 (2012)