Interactions between E-cadherin and microrna deregulation in head and neck cancers: The potential interplay

BioMed Research International

Volumn 2014, Issue , 2014, Pages

  Wong, Thian Sze ^a   Gao, Wei ^a   Chan, Jimmy Yu Wai ^a  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

[No Author keywords available]

Indexed keywords

MICRORNA; MICRORNA 10B; MICRORNA 141; MICRORNA 192; MICRORNA 200; MICRORNA 200A; MICRORNA 200B; MICRORNA 200C; MICRORNA 205; MICRORNA 31; MICRORNA 9; TRANSCRIPTION FACTOR ZEB1; TRANSCRIPTION FACTOR ZEB2; UNCLASSIFIED DRUG; UVOMORULIN; CADHERIN; HOMEODOMAIN PROTEIN; REPRESSOR PROTEIN; TRANSCRIPTION FACTOR; ZEB1 PROTEIN, HUMAN; ZEB2 PROTEIN, HUMAN;

APOPTOSIS; CANCER CELL; CANCER SURVIVAL; CELL ADHESION; CELL INTERACTION; DNA METHYLATION; DNA SEQUENCE; EPIGENETIC REPRESSION; EPITHELIAL MESENCHYMAL TRANSITION; EPITHELIUM CELL; GENE EXPRESSION; GENETIC LINKAGE; GENETIC REGULATION; HEAD AND NECK CANCER; HUMAN; HYPOXIA; NONHUMAN; PROMOTER REGION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN INTERACTION; REGULATORY MECHANISM; REVIEW; SOMATIC MUTATION; WART VIRUS; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENETICS; HEAD AND NECK TUMOR; PATHOLOGY; SQUAMOUS CELL CARCINOMA;

CADHERINS; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; DNA METHYLATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; HEAD AND NECK NEOPLASMS; HOMEODOMAIN PROTEINS; HUMANS; MICRORNAS; REPRESSOR PROTEINS; TRANSCRIPTION FACTORS;

EID: 84929939903     PISSN: 23146133     EISSN: 23146141     Source Type: Journal    
DOI: 10.1155/2014/126038     Document Type: Review

References (75)

1. R. J. Black, F. Bray, J. Ferlay, and D. M. Parkin, "Cancer incidence and mortality in the European Union: cancer registry data and estimates of national incidence for 1990, " European Journal of Cancer, vol. 33, no. 7, pp. 1075-1107, 1990.
2. M. A. Jaber, S. R. Porter, M. S. Gilthorpe, R. Bedi, and C. Scully, "Risk factors for oral epithelial dysplasia-the role of smoking and alcohol, " Oral Oncology, vol. 35, no. 2, pp. 151-156, 1999.
3. T. Rodriguez, A. Altieri, L. Chatenoud et al., "Risk factors for oral and pharyngeal cancer in young adults, " Oral Oncology, vol. 40, no. 2, pp. 207-213, 2004.
4. J. K. Chen, R. V. Katz, and D. J. Krutchkoff, "Intraoral squamous cell carcinoma. Epidemiologic patterns in Connecticut from 1935 to 1985, " Cancer, vol. 66, no. 6, pp. 1288-1296, 1990.
5. C. S. Muir and R. Kirk, "Betel, tobacco, and cancer of the mouth, " British Journal of Cancer, vol. 14, pp. 597-608, 1960.
6. A. Spira, J. Beane, V. Shah et al., "Effects of cigarette smoke on the human airway epithelial cell transcriptome, " Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 27, pp. 10143-10148, 2004.
7. D. P. Slaughter, H. W. Southwick, and W. Smejkal, "Field cancerization in oral stratified squamous epithelium; clinical implications of multicentric origin, " Cancer, vol. 6, no. 5, pp. 963-968, 1953.
8. YH. Joo, SH. Hwang, DI. Sun, KJ. Cho, JO. Park, and MS. Kim, "Relationships between tumor volume and lymphatic metastasis and prognosis in early oral tongue cancer, " Clinical and ExperimentalOtorhinolaryngology, vol. 6, no. 4, p. 243, 2013.
9. H. Fukano, H. Matsuura, Y. Hasegawa, and S. Nakamura, "Depth of invasion as a predictive factor for cervical lymph node metastasis in tongue carcinoma, " Head and Neck, vol. 19, no. 3, pp. 205-210, 1997.
10. H. Yong-Hong, H. Qiao-Ying, P. Yong-Feng, T. Qiu, and F. Zhen-Fu, "Effect of the number and ratio of positive lymph nodes in hypopharyngeal cancer, " Head & Neck, 2013.
11. B. Gumbiner, B. Stevenson, and A. Grimaldi, "The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex, " Journal of Cell Biology, vol. 107, no. 4, pp. 1575-1587, 1988.
12. K. M. Hajra and E. R. Fearon, "Cadherin and catenin alterations in human cancer, " Genes Chromosomes and Cancer, vol. 34, no. 3, pp. 255-268, 2002.
13. Y. Kudo, S. Kitajima, I. Ogawa et al., "Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous β-catenin, " Clinical Cancer Research, vol. 10, no. 16, pp. 5455-5463, 2004.
14. T. Hoteiya, E. Hayashi, K. Satomura, N. Kamata, and M. Nagayama, "Expression of E-cadherin in oral cancer cell lines and its relationship to invasiveness in SCID mice in vivo," Journal of Oral Pathology&Medicine, vol. 28, no. 3, pp. 107-111, 1999.
15. M. Diniz-Freitas, T. Garcφa-Caballero, J. Ant?nez-L≤pez, JM. Gβndara-Rey, and A. Garcφa-Garcφa, "Reduced E-cadherin expression is an indicator of unfavourable prognosis in oral squamous cell carcinoma, " Oral Oncol, vol. 42, no. 2, pp. 190-200, Feb 2006.
16. G. Pannone, A. Santoro, A. Feola et al., "The role of E-cadherin down-regulation in oral cancer: Cdh1 gene expression and epigenetic blockage, " Current Cancer Drug Targets, vol. 14, no. 2, p. 115, 2014.
17. S. Lim, S. Zhang, G. Ishii et al., "Predictive markers for late cervical metastasis in stage I and II invasive squamous cell carcinoma of the oral tongue, " Clinical Cancer Research, vol. 10, no. 1, part 1, pp. 166-172, 2004.
18. K. Yoshiura, Y. Kanai, A. Ochiai, Y. Shimoyama, T. Sugimura, and S. Hirohashi, "Silencing of the E-cadherin invasionsuppressor gene by CpG methylation in human carcinomas," Proceedings of the National Academy of Sciences of the United States of America, vol. 92, no. 16, pp. 7416-7419, 1995.
19. L. Ching-Wen, K. Shih-Han, and Y. Pan-Chyr, "The MiRNAs and epithelial-mesenchymal transition in cancers, " Current Pharmaceutical Design.
20. P. J. Reddig and R. L. Juliano, "Clinging to life: cell to matrix adhesion and cell survival, " Cancer andMetastasis Reviews, vol. 24, no. 3, pp. 425-439, 2005.
21. T. T. Onder, P. B. Gupta, S. A. Mani, J. Yang, E. S. Lander, and R. A. Weinberg, "Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways, " Cancer Research, vol. 68, no. 10, pp. 3645-3654, 2008.
22. S. D. da Silva, M. A. Alaoui-Jamali, F. A. Soares et al., " TWIST1 is a molecular marker for a poor prognosis in oral cancer and represents a potential therapeutic target, " Cancer, vol. 120, no. 3, pp. 352-362, 2014.
23. P. A. Jones and S. B. Baylin, "The epigenomics of cancer, " Cell, vol. 128, no. 4, pp. 683-692, 2007.
24. M. M. Suzuki and A. Bird, "DNA methylation landscapes: provocative insights from epigenomics, " Nature Reviews Genetics, vol. 9, no. 6, pp. 465-476, 2008.
25. M. J. Hoffmann andW. A. Schulz, "Causes and consequences of DNA hypomethylation in human cancer, " Biochemistry and Cell Biology, vol. 83, no. 3, pp. 296-321, 2005.
26. M. Esteller and J. G. Herman, "Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours, " Journal of Pathology, vol. 196, no. 1, pp. 1-7, 2002.
27. C. Y. Zhang, L. Mao, L. Li et al., "Promoter methylation as a common mechanism for inactivating E-cadherin in human salivary gland adenoid cystic carcinoma, " Cancer, vol. 110, no. 1, pp. 87-95, 2007.
28. R. Díez-Pérez, J. Campo-Trapero, J. Cano-Sánchez et al., "Methylation in oral cancer and pre-cancerous lesions (review), " Oncology Reports, vol. 25, no. 5, pp. 1203-1209, 2011.
29. R. V. de Moraes, D. T. Oliveira, G. Landman et al., "E-cadherin abnormalities resulting from CPG methylation promoter in metastatic and nonmetastatic oral cancer, " Head and Neck, vol. 30, no. 1, pp. 85-92, 2008.
30. S. Nagata, T. Hamada, N. Yamada et al., "Aberrant DNA methylation of tumor-related genes in oral rinse: a noninvasive method for detection of oral squamous cell carcinoma, " Cancer, vol. 118, no. 17, pp. 4298-4308, 2012.
31. R. J. Shaw, T. Liloglou, S. N. Rogers et al., "Promotermethylation of P16, RARβ, E-cadherin, cyclin A1 and cytoglobin in oral cancer: quantitative evaluation using pyrosequencing, " British Journal of Cancer, vol. 94, no. 4, pp. 561-568, 2006.
32. G. DSouza, A. R. Kreimer, R. Viscidi et al., "Case-control study of human papillomavirus and oropharyngeal cancer, " The New England Journal of Medicine, vol. 356, no. 19, pp. 1944-1956, 2007.
33. W. M. Mendenhall andH. L. C. Logan, "Human papillomavirus and head and neck cancer, " American Journal of Clinical Oncology, vol. 32, no. 5, pp. 535-539, 2009.
34. M. L. Gillison, "Human papillomavirus-associated head and neck cancer is a distinct epidemiologic, clinical, and molecular entity, " Seminars in Oncology, vol. 31, no. 6, pp. 744-754, 2004.
35. H. C. Hafkamp, J. J. Manni, A. Haesevoets et al., "Marked differences in survival rate between smokers and nonsmokers with HPV 16-associated tonsillar carcinomas, " International Journal of Cancer, vol. 122, no. 12, pp. 2656-2664, 2008.
36. M. Lechner, T. Fenton, J. West et al., "Identification and functional validation of HPV-mediated hypermethylation in head and neck squamous cell carcinoma, " Genome Medicine, vol. 5, no. 2, article 15, 2013.
37. V. Ambros, "The functions of animal microRNAs, " Nature, vol. 431, no. 7006, pp. 350-355, 2004.
38. W. Filipowicz, S. N. Bhattacharyya, and N. Sonenberg, "Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sightØ Nature Reviews Genetics, vol. 9, no. 2, pp. 102-114, 2008.
39. T. Dalmay and D. R. Edwards, "MicroRNAs and the hallmarks of cancer, " Oncogene, vol. 25, no. 46, pp. 6170-6175, 2006.
40. L. Ma, J. Young, H. Prabhala et al., "MiR-9, a MYC/MYCNactivated microRNA, regulates E-cadherin and cancer metastasis," Nature Cell Biology, vol. 12, no. 3, pp. 247-256, 2010.
41. J. Minor, X. Wang, F. Zhang et al., "Methylation of microRNA-9 is a specific and sensitive biomarker for oral and oropharyngeal squamous cell carcinomas, " Oral Oncology, vol. 48, no. 1, pp. 73-78, 2012.
42. T. Yu, K. Liu, Y. Wu et al., "MicroRNA-9 inhibits the proliferation of oral squamous cell carcinoma cells by suppressing expression of CXCR4 via theWnt/β-catenin signaling pathway," Oncogene, 2013.
43. S. Liu, S. M. Kumar, H. Lu et al., "MicroRNA-9 up-regulates E-cadherin through inhibition of NF-κB1-Snail1 pathway in melanoma, " Journal of Pathology, vol. 226, no. 1, pp. 61-72, 2012.
44. L. R. Howe, O. Watanabe, J. Leonard, and A. M. C. Brown, "Twist is up-regulated in response to Wnt1 and inhibits mouse mammary cell differentiation, " Cancer Research, vol. 63, no. 8, pp. 1906-1913, 2003.
45. T. Horikawa, J. Yang, S. Kondo et al., "Twist and epithelialmesenchymal transition are induced by the EBV oncoprotein latent membrane protein 1 and are associated with metastatic nasopharyngeal carcinoma, " Cancer Research, vol. 67, no. 5, pp. 1970-1978, 2007.
46. X. Li, F. Xu, C. Chang et al., "Transcriptional regulation of miR-10a/b by TWIST-1 inmyelodysplastic syndromes, " Haematologica, vol. 98, no. 3, pp. 414-419, 2013.
47. X. J. Sun, H. Liu, P. Zhang, X. D. Zhang, Z. W. Jiang, and C. C. Jiang, "miR-10b promotes migration and invasion in nasopharyngeal carcinoma cells, " Asian Pacific Journal of Cancer Prevention, vol. 14, no. 9, pp. 5535-5537, 2013.
48. F. Zhang, S. Jing, T. Ren, and J. Lin, "MicroRNA-10b promotes the migration of mouse bone marrow-derived mesenchymal stem cells and downregulates the expression of E-cadherin," Molecular Medicine Reports, vol. 8, no. 4, pp. 1084-1088, 2013.
49. G. Li, Z. Wu, Y. Peng et al., "MicroRNA-10b induced by Epstein-Barr virus-encoded latent membrane protein-1 promotes the metastasis of human nasopharyngeal carcinoma cells, " Cancer Letters, vol. 299, no. 1, pp. 29-36, 2010.
50. P. S. Hung, H. F. Tu, S. Y. Kao et al., "miR-31 is upregulated in oral premalignant epithelium and contributes to the immortalization of normal oral keratinocytes, " Carcinogenesis, vol. 35, no. 5, pp. 1162-1171, 2014.
51. C. L. Cottonham, S. Kaneko, and L. Xu, "miR-21 and miR-31 converge on TIAM1 to regulate migration and invasion of colon carcinoma cells, The Journal of Biological Chemistry, vol. 285, no. 46, pp. 35293-35302, 2010.
52. R. K. Das, A. Anura, M. Pal et al., "Epithelio-mesenchymal transitional attributes in oral sub-mucous fibrosis, " Experimental and Molecular Pathology, vol. 95, no. 3, pp. 259-269, 2013.
53. J. Tai, X. Xiao, Z. G. Huang et al., "MicroRNAs regulate epithelial-mesenchymal transition of supraglottic laryngeal cancer, " Chinese Journal of Otorhinolaryngology Head and Neck Surgery, vol. 48, no. 6, pp. 499-503, 2013.
54. A. Krupa, R. Jenkins, D. D. Luo, A. Lewis, A. Phillips, and D. Fraser, "Loss of microRNA-192 promotes fibrogenesis in diabetic nephropathy, " Journal of the American Society of Nephrology, vol. 21, no. 3, pp. 438-447, 2010.
55. K. Aigner, B. Dampier, L. Descovich et al., "The transcription factor ZEB1 (δEF1) promotes tumour cell dedifferentiation by repressing master regulators of epithelial polarity, " Oncogene, vol. 26, no. 49, pp. 6979-6988, 2007.
56. C. Vandewalle, J. Comijn, B. de Craene et al., "SIP1/ZEB2 induces EMT by repressing genes of different epithelial cellcell junctions, " Nucleic Acids Research, vol. 33, no. 20, pp. 6566-6578, 2005.
57. S. Brabletz, K. Bajdak, S. Meidhof et al., "The ZEB1/miR-200 feedback loop controls Notch signalling in cancer cells, " EMBO Journal, vol. 30, no. 4, pp. 770-782, 2011.
58. P. A. Gregory, A. G. Bert, E. L. Paterson et al., "The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1, " Nature Cell Biology, vol. 10, no. 5, pp. 593-601, 2008.
59. S. Park, A. B. Gaur, E. Lengyel, and M. E. Peter, "ThemiR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2, " Genes and Development, vol. 22, no. 7, pp. 894-907, 2008.
60. H. Cao, A. Jheon, X. Li et al., "The Pitx2:miR-200c/141: noggin pathway regulates Bmp signaling and ameloblast differentiation," Development, vol. 140, no. 16, pp. 3348-3359, 2013.
61. S. T. Mees, W. A. Mardin, C. Wendel et al., "EP300-AmiRNAregulated metastasis suppressor gene in ductal adenocarcinomas of the pancreas, " International Journal of Cancer, vol. 126, no. 1, pp. 114-124, 2010.
62. Y. Zhou, Y. Hu, M. Yang et al., "The miR-106b?25 cluster promotes bypass of doxorubicin-induced senescence and increase in motility and invasion by targeting the E-cadherin transcriptional activator EP300, " Cell Death & Differentiation, vol. 21, no. 3, pp. 462-474, 2014.
63. Y. N. Liu, W. W. Lee, C. Y. Wang, T. H. Chao, Y. Chen, and J. H. Chen, "Regulatory mechanisms controlling human E-cadherin gene expression, " Oncogene, vol. 24, no. 56, pp. 8277-8290, 2005.
64. A. M. Fletcher, A. C. Heaford, and D. K. Trask, "Detection of metastatic head and neck squamous cell carcinoma using the relative expression of tissue-specific mir-205, " Translational Oncology, vol. 1, no. 4, pp. 202-208, 2008.
65. L. Tian, J. Zhang, J. Ge et al., "MicroRNA-205 suppresses proliferation and promotes apoptosis in laryngeal squamous cell carcinoma, " MedicalOncology, vol. 31, no. 1, article 785, 2014.
66. S. Liu, M. T. Tetzlaff, A. Liu, B. Liegl-Atzwanger, J. Guo, and X. Xu, "Loss of microRNA-205 expression is associated with melanoma progression, " Laboratory Investigation, vol. 92, no. 7, pp. 1084-1096, 2012.
67. Y. Harazono, T. Muramatsu, H. Endoet al., "miR-655 Is anEMTsuppressive microRNA targeting ZEB1 and TGFBR2, " PLoS ONE, vol. 8, no. 5, Article ID e62757, 2013.
68. C. Yoon, M. Kim, H. Lee et al., "PTTG1 oncogene promotes tumor malignancy via epithelial to mesenchymal transition and expansion of cancer stem cell population, " The Journal of Biological Chemistry, vol. 287, no. 23, pp. 19516-19527, 2012.
69. P. Vaupel, D. K. Kelleher, and M. Höckel, "Oxygenation status of malignant tumors: pathogenesis of hypoxia and significance for tumor therapy, " Seminars in Oncology, vol. 28, no. 2, supplement 8, pp. 29-35, 2001.
70. M. Höckel and P. Vaupel, "Biological consequences of tumor hypoxia, " Seminars in Oncology, vol. 28, no. 2, supplement 8, pp. 36-41, 2001.
71. W. Zeng, P. Liu, W. Pan, S. R. Singh, and Y. Wei, "Hypoxia and hypoxia inducible factors in tumor metabolism, " Cancer Letters, 2014.
72. B. Krishnamachary, D. Zagzag, H. Nagasawa et al., "Hypoxiainducible factor-1-dependent repression of E-cadherin in von Hippel-Lindau tumor suppressor-null renal cell carcinoma mediated by TCF3, ZFHX1A, and ZFHX1B, " Cancer Research, vol. 66, no. 5, pp. 2725-2731, 2006.
73. J. Zhang, Q. Cheng, Y. Zhou, Y. Wang, and X. Chen, "Slug is a key mediator of hypoxia induced cadherin switch in HNSCC: correlations with poor prognosis, " Oral Oncology, vol. 49, no. 11, pp. 1043-1050, Nov 2013.
74. X. Huang, L. Ding, K. L. Bennewith et al., "Hypoxia-inducible mir-210 regulates normoxic gene expression involved in tumor initiation, " Molecular Cell, vol. 35, no. 6, pp. 856-867, 2009.
75. C. J. Liu, M. M. Tsai, P. S. Hung et al., "miR-31 ablates expression of the HIF regulatory factor FIH to activate the HIF pathway in head and neck carcinoma, " Cancer Research, vol. 70, no. 4, pp. 1635-1644, 2010.