MicroRNA-10b promotes the migration of mouse bone marrow-derived mesenchymal stem cells and downregulates the expression of E-cadherin

Molecular Medicine Reports

Volumn 8, Issue 4, 2013, Pages 1084-1088

  Zhang, Fenxi ^a   Jing, Suhua ^a   Ren, Tongming ^a   Lin, Juntang ^a  

^a XINXIANG MEDICAL UNIVERSITY   (China)

Author keywords

Bone marrow derived mesenchymal stem cells; Cell migration; E cadherin expression; MicroRNA 10b

Indexed keywords

CD45 ANTIGEN; LIPOFECTAMINE; MICRORNA 10B; THY 1 ANTIGEN; UVOMORULIN; FIZZY RELATED PROTEIN; FZR1 PROTEIN, MOUSE; MICRORNA; MIRN10 MICRORNA, MOUSE; PTPRC PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; B LYMPHOCYTE; BONE MARROW DERIVED MESENCHYMAL STEM CELL; CELL MIGRATION; CONTROLLED STUDY; DOWN REGULATION; FIBROBLAST; GENETIC TRANSFECTION; MESENCHYMAL STEM CELL; MORPHOLOGY; MOUSE; NONHUMAN; PROTEIN EXPRESSION; UPREGULATION; ANIMAL; CELL CULTURE; CELL MOTION; CELL SHAPE; GENETICS; MESENCHYMAL STROMA CELL; METABOLISM; PHYSIOLOGY; RNA INTERFERENCE;

ANIMALS; ANTIGENS, CD45; CDH1 PROTEINS; CELL MOVEMENT; CELL SHAPE; CELLS, CULTURED; DOWN-REGULATION; MESENCHYMAL STROMAL CELLS; MICE; MICRORNAS; RNA INTERFERENCE;

EID: 84883398250     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2013.1615     Document Type: Article

References (28)

1. Tokaer-Keskin Z, Akar AR, Ayaloglu-Butun F, et al: Timing of induction of cardiomyocyte differentiation for in vitro cultured mesenchymal stem cells: a perspective for emergencies. Can J Physiol Pharmacol 87: 143-150, 2009.
2. Oswad J, Boxberger S, Jorgensen B, et al: Mesenchymal stem cells can be differentiated into endothelial cells in vitro. Stem Cells 22: 377-384, 2004.
3. Hu X, Wei L, Taylor TM, et al: Hypoxic preconditioning enhances bone marrow mesenchymal stem cell migration via Kv2.1 channel and FAK activation. Am J Physiol Cell Physiol 301: C362-C372, 2011.
4. Li C, Feng Y, Coukos G and Zhang L: Therapeutic microRNA strategies in human cancer. AAPS J 11: 747-757, 2009.
5. Kim SJ, Shin JY, Lee KD, et al: MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7. Breast Cancer Res 14: R14, 2012.
6. Cheng CW, Wang HW, Chang CW, et al: MicroRNA-30a inhibits cell migration and invasion by downregulating vimentin expression and is a potential prognostic marker in breast cancer. Breast Cancer Res Treat 134: 1081-1093, 2012.
7. Yan K, Gao J, Yang T, et al: MicroRNA-34a inhibits the proliferation and metastasis of osteosarcoma cells both in vitro and in vivo. PLoS One 7: e33778, 2012.
8. Chen J, Chen XR, Zhang R, et al: MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expression. J Neurooncol 112: 59-66, 2013.
9. Wu D, Ding J, Wang L, et al: microRNA-125b inhibits cell migration and invasion by targeting matrix metallopeptidase 13 in bladder cancer. Oncol Lett 5: 829-834, 2013.
10. Jurmeister S, Baumann M, Balweierz A, et al: MicroRNA-200C represses migration and invasion of breast cancer cells by targeting actin-regulatory proteins FHOD1 and PPM1F. Mol Cell Biol 32: 633-651, 2012.
11. Takeshita N, Mori M, Kano M, et al: miR-203 inhibits the migration and invasion of esophageal squamous cell carcinoma by regulating LASP1. Int J Oncol 41: 1653-1661, 2012.
12. Kinoshita T, Hanazawa T, Nohata N, et al: Tumor suppressive microRNA-218 inhibits cell migration and invasion through targeting laminin-332 in head and neck squamous cell carcinoma. Oncotarget 3: 1386-1400, 2012.
13. Chamorro-Jorganes A, Araldi E, Penalva LO, et al: MicroRNA-16 and microRNA-424 regulate cell-autonomous angiogenic functions in endothelial cells via targeting vascular endothelial growth factor receptor-2 and fibroblast growth receptor-1. Arterioscler Thromb Vasc Biol 31: 2595-2606, 2011.
14. Song J, Kim D and Jin EJ: MicroRNA-488 suppresses cell migration through modulation of the focal adhesion activity during chondrogenic differentiation of chick limb mesenchymal cells. Cell Biol Int 35: 179-185, 2011.
15. Tian Y, Luo A, Cai Y, et al: MicroRNA-10b promotes migration and invasion through KLF4 in human esophageal cancer cell lines. J Biol Chem 285: 7986-7994, 2010.
16. Fan X, Liu Y, Jiang J, et al: miR-20a promotes proliferation and invasion by targeting APP in human ovarian cancer cells. Acta Biochim Biophys Sin (Shanghai) 42: 318-324, 2010.
17. Madhyastha R, Madhyastha H, Nakajima Y, et al: MicroRNA signature in diabetic wound healing: promotive role of miR-21 in fibroblast migration. Int Wound J 9: 355-361, 2012.
18. Zhang LY, Ho-Fun Lee V, Wong AM, et al: MicroRNA-144 promotes cell proliferation, migration and invasion in nasoparyngeal carcinoma through repression PTEN. Carcinogenesis 34: 454-463, 2013.
19. Li QJ, Zhou L, Yang F, et al: MicroRNA-10b promotes migration and invasion through CADM1 in human hepatocellular carcinoma cells. Tumour Biol 33: 1455-1465, 2012.
20. Preis M, Gardner TB, Gordon SR, et al: MicroRNA-10b expression correlates with response to neoadjuvant therapy and survival in pancreatic ductal adenocarcinoma. Clin Cancer Res 17: 5812-5821, 2011.
21. Zhang F, Wang C, Jing S, et al: Lectin-like oxidized LDL receptor-1 expresses in mouse bone marrow-derived mesenchymal stem cells and stimulates their proliferation. Exp Cell Res 319: 1054-1059, 2013.
22. Kim YS, Kwon JS, Hong MH, et al: Promigratory activity of oxytocin on umbilical cord blood-derived mesenchymal stem cells. Artif Organs 34: 453-461, 2010.
23. Spencer HL, Eastham AM, Merry CL, et al: E-cadherin inhibits cell surface localization of the pro-migratory 5T4 oncofetal antigen in mouse embryonic stem cells. Mol Biol Cell 18: 2838-2851, 2007.
24. Li L, Hartley R, Reiss B, et al: E-cadherin plays an essential role in collective directional migration of large epithelial sheets. Cell Mol Life Sci 69: 2779-2789, 2012.
25. Xiao Y, Xu C, Guan J, et al: Discovering dysfunction of multiple microRNAs cooperation in disease by a conserved microRNA co-expression network. PLoS One 7: e32201, 2012.
26. Guessous F, Alvarado-Velez M, Marcinkiewicz L, et al: Oncogenic effects of miR-10b in glioblastoma stem cells. J Neurooncol 112: 153-163, 2013.
27. Jamora C and Fuchs E: Intercellular adhesion, signaling and the cytoskeleton. Nat Cell Biol 4: E101-E108, 2002.
28. Vogelmann R, Nguyen-Tat MD, Giehi K, et al: TGFbeta-induced downregulation of E-cadherin-based cell-cell adhesion depends on PI3-kinase and PTEN. J Cell Sci 118: 4901-4912, 2005.