The role of E-cadherin down-regulation in oral cancer: CDH1 gene expression and epigenetic blockage

Current Cancer Drug Targets

Volumn 14, Issue 2, 2014, Pages 115-127

  Pannone, G ^a   Santoro, A ^a   Feola, A ^b   Bufo, P ^a,h   Papagerakis, P ^c   Lo Muzio, L ^a   Staibano, S ^d   Ionna, F ^e   Longo, F ^e   Franco, R ^e   Aquino, G ^e   Contaldo, M ^b   De Maria, S ^b   Serpico, R ^b   De Rosa, A ^b   Rubini, C ^f   Papagerakis, S ^c   Giovane, A ^b   Tombolini, V ^g,h   Giordano, A ⁱ   Caraglia, M ^b,i   Di Domenico, M ^b,i   more..

^a UNIVERSITY OF FOGGIA   (Italy)

^b SECOND UNIVERSITY OF NAPLES   (Italy)

^c UNIVERSITY OF MICHIGAN SCHOOL OF DENTISTRY   (United States)

^d UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^e NATIONAL CANCER INSTITUTE   (Italy)

^f UNIVERSITÀ POLITECNICA DELLE MARCHE   (Italy)

^g SAPIENZA UNIVERSITY OF ROME   (Italy)

^h Spencer Lorillard Foundation   (Italy)

ⁱ TEMPLE UNIVERSITY   (United States)

Author keywords

CDH1 methylation; Clinical outcome; E cadherin; EGFR; Epithelial Mesenchymal Transition; Methylation Specific PCR; Oral squamous cell carcinoma; Real Time PCR

Indexed keywords

COMPLEMENTARY DNA; DNA METHYLTRANSFERASE; EPIDERMAL GROWTH FACTOR RECEPTOR; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; KERATINOCYTE GROWTH FACTOR; MESSENGER RNA; PLATELET DERIVED GROWTH FACTOR; S ADENOSYLMETHIONINE; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UVOMORULIN; ANTINEOPLASTIC ANTIMETABOLITE; CADHERIN; CDH1 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; ENZYME INHIBITOR; TUMOR MARKER;

ADULT; AGED; ARTICLE; CANCER CELL CULTURE; CANCER PROGNOSIS; CELL PROLIFERATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DNA EXTRACTION; DNA METHYLATION; EPIGENETICS; FEMALE; GENE EXPRESSION; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MAJOR CLINICAL STUDY; MALE; MOUTH SQUAMOUS CELL CARCINOMA; MTT ASSAY; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PROSPECTIVE STUDY; PROTEIN EXPRESSION; PROTEIN METHYLATION; RNA EXTRACTION; VERY ELDERLY; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CASE CONTROL STUDY; DOWN REGULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETIC EPIGENESIS; GENETIC PREDISPOSITION; GENETICS; HEAD AND NECK TUMOR; KAPLAN MEIER METHOD; METABOLISM; MIDDLE AGED; MORTALITY; MOUTH TUMOR; PATHOLOGY; PROGNOSIS; PROMOTER REGION; PROTEIN TRANSPORT; REAL TIME POLYMERASE CHAIN REACTION; SQUAMOUS CELL CARCINOMA; TIME; TUMOR CELL LINE;

ADULT; AGED; AGED, 80 AND OVER; ANTIMETABOLITES, ANTINEOPLASTIC; CADHERINS; CARCINOMA, SQUAMOUS CELL; CASE-CONTROL STUDIES; CELL LINE, TUMOR; DNA METHYLATION; DNA MODIFICATION METHYLASES; DOWN-REGULATION; ENZYME INHIBITORS; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENETIC PREDISPOSITION TO DISEASE; HEAD AND NECK NEOPLASMS; HUMANS; IMMUNOHISTOCHEMISTRY; KAPLAN-MEIER ESTIMATE; MALE; MIDDLE AGED; MOUTH NEOPLASMS; PROGNOSIS; PROMOTER REGIONS, GENETIC; PROTEIN TRANSPORT; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, MESSENGER; TIME FACTORS; TUMOR MARKERS, BIOLOGICAL;

EID: 84893348027     PISSN: 15680096     EISSN: 18735576     Source Type: Journal    
DOI: 10.2174/1568009613666131126115012     Document Type: Article

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