-
1
-
-
0023713859
-
Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking
-
Tysk C, Lindberg E, Järnerot G, et al. Ulcerative colitis and Crohn's disease in an unselected population of monozygotic and dizygotic twins. A study of heritability and the influence of smoking. Gut. 1988;29:990-996.
-
(1988)
Gut
, vol.29
, pp. 990-996
-
-
Tysk, C.1
Lindberg, E.2
Järnerot, G.3
-
2
-
-
0027379179
-
Prevalence and family risk of ulcerative colitis and Crohn's disease: An epidemiological study among Europeans and South Asians in Leicestershire
-
Probert CSJ, Jayanthi V, Hughes AO, et al. Prevalence and family risk of ulcerative colitis and Crohn's disease: an epidemiological study among Europeans and South Asians in Leicestershire. Gut. 1993;34: 1547-1551.
-
(1993)
Gut
, vol.34
, pp. 1547-1551
-
-
Probert, C.S.J.1
Jayanthi, V.2
Hughes, A.O.3
-
3
-
-
83755219473
-
Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review
-
e42; quiz e30
-
Molodecky NA, Soon IS, Rabi DM, et al. Increasing incidence and prevalence of the inflammatory bowel diseases with time, based on systematic review. Gastroenterology. 2012;142:46-54.e42; quiz e30.
-
(2012)
Gastroenterology
, vol.142
, pp. 46-54
-
-
Molodecky, N.A.1
Soon, I.S.2
Rabi, D.M.3
-
4
-
-
84864300619
-
Inflammatory bowel disease in Asia: A systematic review
-
Kamm MA, De Cruz PP, Chan FK, et al. Inflammatory bowel disease in Asia: a systematic review. J Gastroenterol Hepatol. 2012;27:1266-1280.
-
(2012)
J Gastroenterol Hepatol
, vol.27
, pp. 1266-1280
-
-
Kamm, M.A.1
De Cruz, P.P.2
Chan, F.K.3
-
5
-
-
80054785800
-
Estimating trait heritability
-
Wray N, Visscher P. Estimating trait heritability. Nat Educ. 2008;1:29.
-
(2008)
Nat Educ
, vol.1
, pp. 29
-
-
Wray, N.1
Visscher, P.2
-
6
-
-
78649489009
-
Meta-analysis increases to 71 the tally of confirmed Crohn's disease susceptibility loci
-
Franke A, McGovern DPB, Barrett JC, et al. Meta-analysis increases to 71 the tally of confirmed Crohn's disease susceptibility loci. Nat Genet. 2010;42:1118-1125.
-
(2010)
Nat Genet
, vol.42
, pp. 1118-1125
-
-
Franke, A.1
McGovern, D.P.B.2
Barrett, J.C.3
-
7
-
-
33444475803
-
Chronic ulceration of the colon
-
Spriggs EI. Chronic ulceration of the colon. Q J Med. 1934;27:549.
-
(1934)
Q J Med
, vol.27
, pp. 549
-
-
Spriggs, E.I.1
-
8
-
-
0000651358
-
Family occurrences of ulcerative colitis, regional enteritis, and ileocolitis
-
Kirsner JB, Spencer JA. Family occurrences of ulcerative colitis, regional enteritis, and ileocolitis. Ann Intern Med. 1963;59:133-144.
-
(1963)
Ann Intern Med
, vol.59
, pp. 133-144
-
-
Kirsner, J.B.1
Spencer, J.A.2
-
9
-
-
0035990173
-
Familial and sporadic inflammatory bowel disease: Comparison of clinical features and serological markers in a genetically homogeneous population
-
Halme L, Turunen U, Heliö T, et al. Familial and sporadic inflammatory bowel disease: comparison of clinical features and serological markers in a genetically homogeneous population. Scand J Gastroenterol. 2002;37: 692-698.
-
(2002)
Scand J Gastroenterol
, vol.37
, pp. 692-698
-
-
Halme, L.1
Turunen, U.2
Heliö, T.3
-
10
-
-
0027404560
-
Familial empirical risks for inflammatory bowel disease: Differences between Jews and non-Jews
-
Yang H, McElree C, Roth MP, et al. Familial empirical risks for inflammatory bowel disease: differences between Jews and non-Jews. Gut. 1993;34:517-524.
-
(1993)
Gut
, vol.34
, pp. 517-524
-
-
Yang, H.1
McElree, C.2
Roth, M.P.3
-
11
-
-
85017743618
-
DOP021 Familial risk of inflammatory bowel disease: A population-based cohort study, 1977-2011
-
Trier Moller F, Anderson V, Jess T. DOP021 Familial risk of inflammatory bowel disease: a population-based cohort study 1977-2011. JCC. 2014;8(Suppl 1):S24-S25.
-
(2014)
JCC
, vol.8
, pp. S24-S25
-
-
Trier Moller, F.1
Anderson, V.2
Jess, T.3
-
12
-
-
0029788997
-
Familial aggregation in Crohn's disease: Increased age-adjusted risk and concordance in clinical characteristics
-
Peeters M, Nevens H, Baert F, et al. Familial aggregation in Crohn's disease: increased age-adjusted risk and concordance in clinical characteristics. Gastroenterology. 1996;111:597-603.
-
(1996)
Gastroenterology
, vol.111
, pp. 597-603
-
-
Peeters, M.1
Nevens, H.2
Baert, F.3
-
14
-
-
0029970133
-
Clinical patterns of familial inflammatory bowel disease
-
Satsangi J, Grootscholten C, Holt H, et al. Clinical patterns of familial inflammatory bowel disease. Gut. 1996;38:738-741.
-
(1996)
Gut
, vol.38
, pp. 738-741
-
-
Satsangi, J.1
Grootscholten, C.2
Holt, H.3
-
15
-
-
0033034042
-
Crohn's disease severity in familial and sporadic cases
-
Carbonnel F, Macaigne G, Beaugerie L, et al. Crohn's disease severity in familial and sporadic cases. Gut. 1999;44:91-95.
-
(1999)
Gut
, vol.44
, pp. 91-95
-
-
Carbonnel, F.1
MacAigne, G.2
Beaugerie, L.3
-
16
-
-
0002791320
-
Genetic complexities of inflammatory bowel disease and its distribution among the Jewish people
-
Bonne-Tamir B, Adam A, eds Oxford, United Kingdom: Oxford, University Press
-
Rotter JI, Yang H, Shohat T. Genetic complexities of inflammatory bowel disease and its distribution among the Jewish people. In: Bonne-Tamir B, Adam A, eds. Genetic Diversity Among Jews: Disease and Markers at the DNA Level. Oxford, United Kingdom: Oxford University Press; 1992: 395-411.
-
(1992)
Genetic Diversity among Jews: Disease and Markers at the DNA Level
, pp. 395-411
-
-
Rotter, J.I.1
Yang, H.2
Shohat, T.3
-
17
-
-
0026516962
-
Crohn's disease among ethnic groups in a large health maintenance organization
-
Kurata JH, Kantor-Fish S, Frankl H, et al. Crohn's disease among ethnic groups in a large health maintenance organization. Gastroenterology. 1992;102:1940-1948.
-
(1992)
Gastroenterology
, vol.102
, pp. 1940-1948
-
-
Kurata, J.H.1
Kantor-Fish, S.2
Frankl, H.3
-
18
-
-
0037221395
-
Crohn's disease-associated NOD2 variants share a signalling defect in response to lipopolysaccharide and peptidoglycan
-
Bonen DK, Ogura Y, Nicolae DL, et al. Crohn's disease-associated NOD2 variants share a signalling defect in response to lipopolysaccharide and peptidoglycan. Gastroenterology. 2003;124:140-146.
-
(2003)
Gastroenterology
, vol.124
, pp. 140-146
-
-
Bonen, D.K.1
Ogura, Y.2
Nicolae, D.L.3
-
19
-
-
84861328957
-
Genetics of inflammatory bowel disease in Asia: Systematic review and meta-analysis
-
Ng SC, Tsoi KK, Kamm MA, et al. Genetics of inflammatory bowel disease in Asia: systematic review and meta-analysis. Inflamm Bowel Dis. 2012;18:1164-1176.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 1164-1176
-
-
Ng, S.C.1
Tsoi, K.K.2
Kamm, M.A.3
-
20
-
-
70949087383
-
Inflammatory bowel disease and mutations affecting the interleukin-10 receptor
-
Glocker EO, Kotlarz D, Boztug K, et al. Inflammatory bowel disease and mutations affecting the interleukin-10 receptor. N Engl J Med. 2009;361: 2033-2045.
-
(2009)
N Engl J Med
, vol.361
, pp. 2033-2045
-
-
Glocker, E.O.1
Kotlarz, D.2
Boztug, K.3
-
21
-
-
77958003426
-
Infant colitis-it's in the genes
-
Glocker EO, Frede N, Perro M, et al. Infant colitis-it's in the genes. Lancet. 2010;376:1272.
-
(2010)
Lancet
, vol.376
, pp. 1272
-
-
Glocker, E.O.1
Frede, N.2
Perro, M.3
-
22
-
-
84927783778
-
Novel de novo mutations of the interleukin-10 receptor gene lead to infantile onset inflammatory bowel disease
-
Lee CH, Hsu P, Nanan B, et al. Novel de novo mutations of the interleukin-10 receptor gene lead to infantile onset inflammatory bowel disease. J Crohns Colitis. 2014;8:1551-1556.
-
(2014)
J Crohns Colitis
, vol.8
, pp. 1551-1556
-
-
Lee, C.H.1
Hsu, P.2
Nanan, B.3
-
23
-
-
33845525769
-
Early lethal autosomal recessive enterocolitis: Report of a second family
-
Megarbane A, Sayad R. Early lethal autosomal recessive enterocolitis: report of a second family. Clin Genet. 2007;71:89-90.
-
(2007)
Clin Genet
, vol.71
, pp. 89-90
-
-
Megarbane, A.1
Sayad, R.2
-
24
-
-
0016224530
-
A lethal autosomal recessive entero-colitis of early infancy
-
Fried K, Vure E. A lethal autosomal recessive entero-colitis of early infancy. Clin Genet. 1974;6:195-196.
-
(1974)
Clin Genet
, vol.6
, pp. 195-196
-
-
Fried, K.1
Vure, E.2
-
26
-
-
0025966488
-
Familial occurrence of inflammatory bowel disease
-
Orholm M, Munkholm P, Langholz E, et al. Familial occurrence of inflammatory bowel disease. N Engl J Med. 1991;324:84-88.
-
(1991)
N Engl J Med
, vol.324
, pp. 84-88
-
-
Orholm, M.1
Munkholm, P.2
Langholz, E.3
-
27
-
-
0033773642
-
Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study
-
Orholm M, Binder V, Sorensen TI, et al. Concordance of inflammatory bowel disease among Danish twins. Results of a nationwide study. Scand J Gastroenterol. 2000;35:1075-1081.
-
(2000)
Scand J Gastroenterol
, vol.35
, pp. 1075-1081
-
-
Orholm, M.1
Binder, V.2
Sorensen, T.I.3
-
28
-
-
33644647470
-
Disease concordance, zygosity, and NOD2/CARD15 status: Follow-up of a population-based cohort of Danish twins with inflammatory bowel disease
-
Jess T, Riis L, Jespersgaard C, et al. Disease concordance, zygosity, and NOD2/CARD15 status: follow-up of a population-based cohort of Danish twins with inflammatory bowel disease. Am J Gastroenterol. 2005;100: 2486-2492.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 2486-2492
-
-
Jess, T.1
Riis, L.2
Jespersgaard, C.3
-
29
-
-
47949106374
-
Epidemiology of inflammatory bowel disease in a German twin cohort: Results of a nationwide study
-
Spehlmann ME, Begun AZ, Burghardt J, et al. Epidemiology of inflammatory bowel disease in a German twin cohort: results of a nationwide study. Inflamm Bowel Dis. 2008;14:968-976.
-
(2008)
Inflamm Bowel Dis
, vol.14
, pp. 968-976
-
-
Spehlmann, M.E.1
Begun, A.Z.2
Burghardt, J.3
-
30
-
-
0038620498
-
Inflammatory bowel disease in a Swedish twin cohort: A long-term follow-up of concordance and clinical characteristics
-
Halfvarson J, Bodin L, Tysk C, et al. Inflammatory bowel disease in a Swedish twin cohort: a long-term follow-up of concordance and clinical characteristics. Gastroenterology. 2003;124:1767-1773.
-
(2003)
Gastroenterology
, vol.124
, pp. 1767-1773
-
-
Halfvarson, J.1
Bodin, L.2
Tysk, C.3
-
31
-
-
84858693205
-
Role of genetic and environmental factors in British twins with inflammatory bowel disease
-
Ng SC, Woodrow S, Patel N, et al. Role of genetic and environmental factors in British twins with inflammatory bowel disease. Inflamm Bowel Dis. 2012;18:725-736.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 725-736
-
-
Ng, S.C.1
Woodrow, S.2
Patel, N.3
-
32
-
-
84865214259
-
The continuing value of twin studies in the omics era
-
van Dongen J, Slagboom PE, Draisma HH, et al. The continuing value of twin studies in the omics era. Nat Rev Genet. 2012;13:640-653.
-
(2012)
Nat Rev Genet
, vol.13
, pp. 640-653
-
-
Van Dongen, J.1
Slagboom, P.E.2
Draisma, H.H.3
-
34
-
-
78650144816
-
Update on the heritability of Inflammatory Bowel Disease: The importance of twin studies
-
Brand SR. Update on the heritability of Inflammatory Bowel Disease: the importance of twin studies. Inflamm Bowel Dis. 2011;17:1-5.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 1-5
-
-
Brand, S.R.1
-
35
-
-
77955269564
-
Concordance for IBD among twins compared to ordinary siblings-a Nowegian population based study
-
Bengtson MB, Aamodt G, Vatn MH, et al. Concordance for IBD among twins compared to ordinary siblings-a Nowegian population based study. J Crohns Colitis. 2010;4:312-318.
-
(2010)
J Crohns Colitis
, vol.4
, pp. 312-318
-
-
Bengtson, M.B.1
Aamodt, G.2
Vatn, M.H.3
-
36
-
-
0014067238
-
The NAS-NRC twin panel: Methods of construction of the panel, zygosity diagnosis, and proposed use
-
Jablon S, Neel JV, Gershowitz H, et al. The NAS-NRC twin panel: methods of construction of the panel, zygosity diagnosis, and proposed use. Am J Hum Genet. 1967;19:133-161.
-
(1967)
Am J Hum Genet
, vol.19
, pp. 133-161
-
-
Jablon, S.1
Neel, J.V.2
Gershowitz, H.3
-
37
-
-
84896720959
-
Estimating twin concordance for bivariate competing risks twin data
-
Scheike TH, Holst KK, Hjelmborg JB. Estimating twin concordance for bivariate competing risks twin data. Stat Med. 2014;33:1193-1204.
-
(2014)
Stat Med
, vol.33
, pp. 1193-1204
-
-
Scheike, T.H.1
Holst, K.K.2
Hjelmborg, J.B.3
-
38
-
-
77955058518
-
The inheritance of liability to certain diseases, estimated from the incidence among relatives
-
Falconer DS. The inheritance of liability to certain diseases, estimated from the incidence among relatives. Ann Hum Genet. 1966;29:51-76.
-
(1966)
Ann Hum Genet
, vol.29
, pp. 51-76
-
-
Falconer, D.S.1
-
39
-
-
0015422250
-
The use of mutiple thresholds in determining the mode of transmission of semi-continuous traits
-
Reich T, James JW, Morris CA. The use of mutiple thresholds in determining the mode of transmission of semi-continuous traits. Ann Hum Genet. 1972;36:163-184.
-
(1972)
Ann Hum Genet
, vol.36
, pp. 163-184
-
-
Reich, T.1
James, J.W.2
Morris, C.A.3
-
40
-
-
84905666024
-
Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data
-
International IBD Genetics Consortium
-
Chen GB, Lee SH, Brion MJ, et al; International IBD Genetics Consortium. Estimation and partitioning of (co)heritability of inflammatory bowel disease from GWAS and immunochip data. Hum Mol Genet. 2014;23:4710-4720.
-
(2014)
Hum Mol Genet
, vol.23
, pp. 4710-4720
-
-
Chen, G.B.1
Lee, S.H.2
Brion, M.J.3
-
41
-
-
84889237300
-
How meaningful are heritability estimates of liability?
-
Benchek PH, Morris NJ. How meaningful are heritability estimates of liability? Hum Genet. 2013;132:1351-1360.
-
(2013)
Hum Genet
, vol.132
, pp. 1351-1360
-
-
Benchek, P.H.1
Morris, N.J.2
-
42
-
-
0036797562
-
Epistasis: What it means, what it doesn't mean, and statistical methods to detect it in humans
-
Cordell HJ. Epistasis: what it means, what it doesn't mean, and statistical methods to detect it in humans. Hum Mol Genet. 2002;11:2463-2468.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2463-2468
-
-
Cordell, H.J.1
-
43
-
-
35348911343
-
Genome partitioning of genetic variation for height from 11, 214 sibling pairs
-
Visscher PM, Macgregora S, Benyamina B, et al. Genome partitioning of genetic variation for height from 11, 214 sibling pairs. Am J Med Genet. 2007;81:1104-1110.
-
(2007)
Am J Med Genet
, vol.81
, pp. 1104-1110
-
-
Visscher, P.M.1
MacGregora, S.2
Benyamina, B.3
-
44
-
-
70350221909
-
Copy number variation in human health, disease, and evolution
-
Zhang F, Gu W, Hurles ME, et al. Copy number variation in human health, disease, and evolution. Annu Rev Genomics Hum Genet. 2009; 10:451-481.
-
(2009)
Annu Rev Genomics Hum Genet
, vol.10
, pp. 451-481
-
-
Zhang, F.1
Gu, W.2
Hurles, M.E.3
-
45
-
-
84866537913
-
De novo and inherited CNVs in MZ twin pairs selected for discordance and concordance on attention problems
-
Ehli EA, Abdellaoui A, Hu Y, et al. De novo and inherited CNVs in MZ twin pairs selected for discordance and concordance on attention problems. Eur J Hum Genet. 2012;11:1037-1043.
-
(2012)
Eur J Hum Genet
, vol.11
, pp. 1037-1043
-
-
Ehli, E.A.1
Abdellaoui, A.2
Hu, Y.3
-
46
-
-
84897038943
-
Copy number variation distribution in six monozygotic twin pairs discordant for schizophrenia
-
Castellani CA, Awamleh Z, Melka MG, et al. Copy number variation distribution in six monozygotic twin pairs discordant for schizophrenia. Twin Res Hum Genet. 2014;17:108-120.
-
(2014)
Twin Res Hum Genet
, vol.17
, pp. 108-120
-
-
Castellani, C.A.1
Awamleh, Z.2
Melka, M.G.3
-
48
-
-
0031921465
-
Genetic and environmental influences on human behavioural differences
-
McGue M, Bouchard TJ Jr. Genetic and environmental influences on human behavioural differences. Annu Rev Neurosci. 1998;21:1-24.
-
(1998)
Annu Rev Neurosci
, vol.21
, pp. 1-24
-
-
McGue, M.1
Bouchard, T.J.2
-
49
-
-
27644567142
-
The equal environments assumption of classical twin studies may not hold
-
Richardson K, Norgate S. The equal environments assumption of classical twin studies may not hold. Br J Educ Psychol. 2005;75:339-350.
-
(2005)
Br J Educ Psychol
, vol.75
, pp. 339-350
-
-
Richardson, K.1
Norgate, S.2
-
50
-
-
33745745597
-
A test of the equal environment assumption (EEA) in multivariate twin studies
-
Derks EM, Dolan CV, Boomsma DI. A test of the equal environment assumption (EEA) in multivariate twin studies. Twin Res Hum Genet. 2006;9:403-411.
-
(2006)
Twin Res Hum Genet
, vol.9
, pp. 403-411
-
-
Derks, E.M.1
Dolan, C.V.2
Boomsma, D.I.3
-
51
-
-
79952489475
-
Estimating missing heritability for disease from genome-wide association studies
-
Lee SH, Wray NR, Goddard ME, et al. Estimating missing heritability for disease from genome-wide association studies. Am J Hum Genet. 2011; 88:294-305.
-
(2011)
Am J Hum Genet
, vol.88
, pp. 294-305
-
-
Lee, S.H.1
Wray, N.R.2
Goddard, M.E.3
-
52
-
-
84868336049
-
Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease
-
Jostins L, Ripke S, Weersma RK, et al. Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease. Nature. 2012;491:119-124.
-
(2012)
Nature
, vol.491
, pp. 119-124
-
-
Jostins, L.1
Ripke, S.2
Weersma, R.K.3
-
53
-
-
33846642542
-
The genetics of schizophrenia
-
Sullivan PF. The genetics of schizophrenia. PLoS Med. 2005;2:e212.
-
(2005)
PLoS Med
, vol.2
, pp. e212
-
-
Sullivan, P.F.1
-
54
-
-
33845797961
-
The genetics of autistic disorders and its clinical relevance: A review of the literature
-
Freitag CM. The genetics of autistic disorders and its clinical relevance: a review of the literature. Mol Psychiatry. 2007;12:2-22.
-
(2007)
Mol Psychiatry
, vol.12
, pp. 2-22
-
-
Freitag, C.M.1
-
55
-
-
77955133892
-
Estimating effects and making predictions from genome-wide marker data
-
Goddard ME, Wray NR, Verbyla K, et al. Estimating effects and making predictions from genome-wide marker data. Stat Sci. 2009;24:517-529.
-
(2009)
Stat Sci
, vol.24
, pp. 517-529
-
-
Goddard, M.E.1
Wray, N.R.2
Verbyla, K.3
-
56
-
-
79954479289
-
Genome-wide association studies and Crohn's disease
-
Lee JC, Parkes M. Genome-wide association studies and Crohn's disease. Brief Funct Genomics. 2011;10:71-76.
-
(2011)
Brief Funct Genomics
, vol.10
, pp. 71-76
-
-
Lee, J.C.1
Parkes, M.2
-
57
-
-
44349132708
-
Common and rare variants in multifactorial susceptibility to common diseases
-
Bodmer W, Bonilla C. Common and rare variants in multifactorial susceptibility to common diseases. Nat Genet. 2008;40:695-701.
-
(2008)
Nat Genet
, vol.40
, pp. 695-701
-
-
Bodmer, W.1
Bonilla, C.2
-
58
-
-
84878994629
-
Negligible impact of rare autoimmune-locus coding-region variants on missing heritability
-
Hunt KA, Mistry V, Bockett NA, et al. Negligible impact of rare autoimmune-locus coding-region variants on missing heritability. Nature. 2013;498:232-235.
-
(2013)
Nature
, vol.498
, pp. 232-235
-
-
Hunt, K.A.1
Mistry, V.2
Bockett, N.A.3
-
59
-
-
79851487367
-
Synthetic associations created by rare variants do not explain most GWAS results
-
Wray N, Purcell S, Visscher P. Synthetic associations created by rare variants do not explain most GWAS results. PLoS Biol. 2011;9:e1000579.
-
(2011)
PLoS Biol
, vol.9
, pp. e1000579
-
-
Wray, N.1
Purcell, S.2
Visscher, P.3
-
60
-
-
77954133026
-
Estimation of effect size distribution from genome-wide association studies and implications for future discoveries
-
Park JH, Wacholder S, Gail MH, et al. Estimation of effect size distribution from genome-wide association studies and implications for future discoveries. Nat Genet. 2010;42:570-575.
-
(2010)
Nat Genet
, vol.42
, pp. 570-575
-
-
Park, J.H.1
Wacholder, S.2
Gail, M.H.3
-
61
-
-
77954140531
-
Common SNPs explain a large proportion of the heritability for human height
-
Yang J, Benyamin B, McEvoy BP, et al. Common SNPs explain a large proportion of the heritability for human height. Nat Genet. 2010;42:565-569.
-
(2010)
Nat Genet
, vol.42
, pp. 565-569
-
-
Yang, J.1
Benyamin, B.2
McEvoy, B.P.3
-
62
-
-
84892746185
-
Quantifying missing heritability at known GWAS loci
-
Gusev A, Bhatia G, Zaitlen N, et al. Quantifying missing heritability at known GWAS loci. PLoS Genet. 2013;9:e1003993.
-
(2013)
PLoS Genet
, vol.9
, pp. e1003993
-
-
Gusev, A.1
Bhatia, G.2
Zaitlen, N.3
-
63
-
-
84856405512
-
The mystery of missing heritability: Genetic interactions create phantom heritability
-
Zuk O, Hechter E, Sunyaev SR, et al. The mystery of missing heritability: genetic interactions create phantom heritability. Proc Natl Acad Sci USA. 2012;109:1193-1198.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 1193-1198
-
-
Zuk, O.1
Hechter, E.2
Sunyaev, S.R.3
-
64
-
-
13944273766
-
The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction
-
Pierik M, Yang H, Barmada MM, et al. The IBD international genetics consortium provides further evidence for linkage to IBD4 and shows gene-environment interaction. Inflamm Bowel Dis. 2005;11:1-7.
-
(2005)
Inflamm Bowel Dis
, vol.11
, pp. 1-7
-
-
Pierik, M.1
Yang, H.2
Barmada, M.M.3
-
65
-
-
77953307288
-
Environmental risk factors for inflammatory bowel disease
-
Molodecky NA, Kaplan GG. Environmental risk factors for inflammatory bowel disease. Gastroenterol Hepatol (N Y). 2010;6:339-346.
-
(2010)
Gastroenterol Hepatol (N Y)
, vol.6
, pp. 339-346
-
-
Molodecky, N.A.1
Kaplan, G.G.2
-
66
-
-
84859795659
-
Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway
-
Nimmo ER, Prendergast JG, Aldhous MC, et al. Genome-wide methylation profiling in Crohn's disease identifies altered epigenetic regulation of key host defense mechanisms including the Th17 pathway. Inflamm Bowel Dis. 2012;18:889-899.
-
(2012)
Inflamm Bowel Dis
, vol.18
, pp. 889-899
-
-
Nimmo, E.R.1
Prendergast, J.G.2
Aldhous, M.C.3
-
67
-
-
78650119948
-
Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease
-
Wu F, Guo NJ, Tian H, et al. Peripheral blood microRNAs distinguish active ulcerative colitis and Crohn's disease. Inflamm Bowel Dis. 2011;17: 241-250.
-
(2011)
Inflamm Bowel Dis
, vol.17
, pp. 241-250
-
-
Wu, F.1
Guo, N.J.2
Tian, H.3
-
68
-
-
79251550434
-
Differential patterns of histone acetylation in inflammatory bowel diseases
-
Tsaprouni L, Ito K, Powell J, et al. Differential patterns of histone acetylation in inflammatory bowel diseases. J Inflamm (Lond). 2011;8:1.
-
(2011)
J Inflamm (Lond)
, vol.8
, pp. 1
-
-
Tsaprouni, L.1
Ito, K.2
Powell, J.3
-
69
-
-
84896092821
-
The treatment-naive microbiome in new-onset Crohn's disease
-
Gevers D, Kugathasan S, Denson Lee A, et al. The treatment-naive microbiome in new-onset Crohn's disease. Cell Host Microbe. 2014;15:382-392.
-
(2014)
Cell Host Microbe
, vol.15
, pp. 382-392
-
-
Gevers, D.1
Kugathasan, S.2
Denson Lee, A.3
-
70
-
-
84861980130
-
Interactions between the microbiota and the immune system
-
Hooper LV, Littman DR, Macpherson AJ. Interactions between the microbiota and the immune system. Science. 2012;336:1268-1273.
-
(2012)
Science
, vol.336
, pp. 1268-1273
-
-
Hooper, L.V.1
Littman, D.R.2
MacPherson, A.J.3
-
71
-
-
34248136828
-
Inflammatory bowel disease: Cause and immunobiology
-
Baumgart DC, Carding SR. Inflammatory bowel disease: cause and immunobiology. Lancet. 2007;369:1627-1640.
-
(2007)
Lancet
, vol.369
, pp. 1627-1640
-
-
Baumgart, D.C.1
Carding, S.R.2
-
72
-
-
0031011057
-
The genetics of inflammatory bowel disease
-
Satsangi J, Jewell DP, Bell JI. The genetics of inflammatory bowel disease. Gut. 1997;40:572-574.
-
(1997)
Gut
, vol.40
, pp. 572-574
-
-
Satsangi, J.1
Jewell, D.P.2
Bell, J.I.3
-
73
-
-
0035978651
-
Association of NOD2 leucinerich repeat variants with susceptibility to Crohn's disease
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucinerich repeat variants with susceptibility to Crohn's disease. Nature. 2001; 411:599-603.
-
(2001)
Nature
, vol.411
, pp. 599-603
-
-
Hugot, J.P.1
Chamaillard, M.2
Zouali, H.3
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