Familial and sporadic inflammatory bowel disease: Comparison of clinical features and serological markers in a genetically homogeneous population

Scandinavian Journal of Gastroenterology

Volumn 37, Issue 6, 2002, Pages 692-698

  Halme, Leena ^a   Turunen, U ^a   Helio T ^a   Paavola, P ^a   Walle, T ^a   Miettinen, A ^a   Jarvinen H ^a   Kontula, K ^a   Farkkila M ^a  

^a HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

Author keywords

Crohn disease; Serological markers; Ulcerative colitis

Indexed keywords

FUNGUS ANTIBODY; IMMUNOGLOBULIN A ANTIBODY; IMMUNOGLOBULIN G ANTIBODY; NEUTROPHIL CYTOPLASMIC ANTIBODY; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; AGED; ARTICLE; CONTROLLED STUDY; CROHN DISEASE; DISEASE ASSOCIATION; DISEASE COURSE; DISEASE PREDISPOSITION; ENTERITIS; EUROPE; FAMILIAL DISEASE; FEMALE; HUMAN; ILEUM DISEASE; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RACE DIFFERENCE; RISK FACTOR; SACCHAROMYCES CEREVISIAE; SCHOOL CHILD; SEROLOGY; SMOKING; ULCERATIVE COLITIS; AGE DISTRIBUTION; CHILD; COHORT ANALYSIS; COMPARATIVE STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FINLAND; GENETICS; INCIDENCE; MIDDLE AGED; PREDICTION AND FORECASTING; PROBABILITY; PROGNOSIS; RISK ASSESSMENT; SEX RATIO;

ADOLESCENT; ADULT; AGE DISTRIBUTION; AGED; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; BIOLOGICAL MARKERS; CHILD; COHORT STUDIES; COLITIS, ULCERATIVE; COMPARATIVE STUDY; CROHN DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FINLAND; HUMAN; INCIDENCE; INFLAMMATORY BOWEL DISEASES; MALE; MIDDLE AGE; PREDICTIVE VALUE OF TESTS; PROBABILITY; PROGNOSIS; RISK ASSESSMENT; SEX DISTRIBUTION; SUPPORT, NON-U.S. GOV'T; HUMANS; MIDDLE AGED;

EID: 0035990173     PISSN: 00365521     EISSN: None     Source Type: Journal    
DOI: 10.1080/00365520212511     Document Type: Article

References (35)

1. Mapping of a susceptibility locus for Crohn's disease on chromosome 16
2. Two-stage genome-wide search in inflammatory bowel disease: Evidence for susceptibility loci on chromosomes 3, 7 and 12
3. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn disease and chromosome 16
4. Association between insertion in NOD2 gene and Crohn's disease in German and British populations
5. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
6. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
7. Genetic analysis in Finnish families with inflammatory bowel disease supports linkage to chromosome 3p21
8. Genome wide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
9. Smoking and inflammatory bowel disease. A case-control study
10. Transdermal nicotine for mildly to moderately active ulcerative colitis. A randomised double-blind, placebo-controlled trial
11. Smoking cessation and the course of Crohn's disease: An intervention study
12. Neutrophil autoantibodies in ulcerative colitis: Familial aggregation and genetic heterogeneity
13. Neutrophil antibodies: A genetic marker in primary sclerosing cholangitis and ulcerative colitis
14. Antineutrophil antibodies in familial inflammatory bowel disease
15. Anti-Saccharomyces cerevisiae mannan antibodies combined with antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease; prevalence and diagnostic role
16. Familial expession of anti-Saccharomyces cerevisiae mannan antibodies in affected and unaffected relatives of patients with Crohn's disease
17. Anti-Saccharomyces cerevisiae antibodies in inflammatory bowel disease: A family study
18. Classification of inflammatory bowel disease
19. A simple classification of Crohn's disease: Report of the working party for the world congresses of gastroenterology Vienna 1998
20. International consensus statement on testing and reporting of antineutrophil cytoplasmic antibodies (ANCA)
21. Familial occurrence of inflammatory bowel disease
22. Prevalence of inflammatory bowel disease among relatives of patients with Crohn's disease
23. Crohn's disease severity in familial sporadic cases
24. Familial aggregation in Crohn's disease: Increased age-adjusted risk and concordance in clinical characteristics
25. Clinical patterns of familial inflammatory bowel disease
26. Clinical characteristics of Crohn's disease in 72 families
27. Crohn's disease: Influence of age at diagnosis on site and clinical type of disease
28. Relationship between site of disease and familial occurrence in Crohn's disease
29. Prevalence of inflammatory bowel disease among relatives of patients with ulcerative colitis
30. Why children with inflammatory bowel disease are diagnosed at a younger age than their affected parent
31. Familial empirical risks for inflammatory bowel disease: Differences between Jews and non-Jews
32. Risk of ulcerative colitis and Crohn's disease among offspring of patients with chronic inflammatory bowel disease
33. Comparative study of ASCA (Anti-Saccharomyces cerevisiae antibody) assay in inflammatory bowel disease
34. Serum antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease are mainly associated with ulcerative colitis. A correlation study between perinuclear antineutrophil cytoplasmic autoantibodies and clinical parameters, medical, and surgical treatment
35. Diagnostic value of anti-Saccharomyces cerevisiae and antineutrophil cytoplasmic autoantibodies in inflammatory bowel disease