Epidermal growth factor-like domain 7 promotes migration and invasion of human trophoblast cells through activation of MAPK, PI3K and NOTCH signaling pathways

Molecular Human Reproduction

Volumn 21, Issue 5, 2015, Pages 435-451

  Massimiani, M ^a   Vecchione, L ^a   Piccirilli, D ^a   Spitalieri, P ^a   Amati, F ^a   Salvi, S ^b   Ferrazzani, S ^b   Stuhlmann, H ^c   Campagnolo, L ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b CATHOLIC UNIVERSITY   (Italy)

^c WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

EGFL7; MAPK; NOTCH signaling; PI3K; Trophoblast migration

Indexed keywords

EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR LIKE DOMAIN 7 PROTEIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; NOTCH RECEPTOR; PHOSPHATIDYLINOSITOL 3 KINASE; UNCLASSIFIED DRUG; EGFL7 PROTEIN, HUMAN; EGFR PROTEIN, HUMAN; ENDOTHELIAL CELL GROWTH FACTOR; ENZYME INHIBITOR; NOTCH1 PROTEIN, HUMAN; NOTCH1 RECEPTOR; RECOMBINANT PROTEIN;

ARTICLE; CELL INVASION; CELL MIGRATION; CELL MOTILITY; CELL PROLIFERATION; CHORIOCARCINOMA CELL LINE; CONTROLLED STUDY; ENZYME ACTIVATION; FEMALE; FIRST TRIMESTER PREGNANCY; GENE ACTIVATION; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; PLACENTA DISORDER; PRIORITY JOURNAL; PROTEIN DOMAIN; SIGNAL TRANSDUCTION; TROPHOBLAST; AGONISTS; ANTAGONISTS AND INHIBITORS; CELL CULTURE; CELL MOTION; CHEMISTRY; CYTOLOGY; DRUG EFFECTS; GENETICS; HEK293 CELL LINE; METABOLISM; PREGNANCY; REPRODUCTION; RNA INTERFERENCE; TUMOR CELL LINE; UMBILICAL VEIN ENDOTHELIAL CELL; UPREGULATION;

CELL LINE, TUMOR; CELL MOVEMENT; CELLS, CULTURED; ENDOTHELIAL GROWTH FACTORS; ENZYME INHIBITORS; FEMALE; HEK293 CELLS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MAP KINASE SIGNALING SYSTEM; PHOSPHATIDYLINOSITOL 3-KINASE; PLACENTATION; PREGNANCY; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECEPTOR, NOTCH1; RECOMBINANT PROTEINS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TROPHOBLASTS; UP-REGULATION;

EID: 84929741963     PISSN: 13609947     EISSN: 14602407     Source Type: Journal    
DOI: 10.1093/molehr/gav006     Document Type: Article

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