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Volumn 62, Issue 2, 2015, Pages 198-212

Epithelial-specific ETS-1 (ESE1/ELF3) regulates apoptosis of intestinal epithelial cells in ulcerative colitis via accelerating NF-κB activation

Author keywords

Apoptosis; Epithelial specific ETS 1; Intestinal epithelial cell; Ulcerative colitis

Indexed keywords

CASPASE 3; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BCL XL; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR ETS 1; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA; DNA BINDING PROTEIN; ELF3 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR ETS; TUMOR NECROSIS FACTOR;

EID: 84929705175     PISSN: 0257277X     EISSN: 15590755     Source Type: Journal    
DOI: 10.1007/s12026-015-8651-3     Document Type: Article
Times cited : (23)

References (55)
  • 1
    • 84869213229 scopus 로고    scopus 로고
    • Immune markers and differential signaling networks in ulcerative colitis and Crohn’s disease
    • PID: 22467146
    • Christophi GP, Rong R, Holtzapple PG, Massa PT, Landas SK. Immune markers and differential signaling networks in ulcerative colitis and Crohn’s disease. Inflamm Bowel Dis. 2012;18(12):2342–56. doi:10.1002/ibd.22957.
    • (2012) Inflamm Bowel Dis , vol.18 , Issue.12 , pp. 2342-2356
    • Christophi, G.P.1    Rong, R.2    Holtzapple, P.G.3    Massa, P.T.4    Landas, S.K.5
  • 2
    • 84866026484 scopus 로고    scopus 로고
    • Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BC38XhtlCitrjJ, PID: 22970173
    • Sohn JJ, Schetter AJ, Yfantis HG, Ridnour LA, Horikawa I, Khan MA, et al. Macrophages, nitric oxide and microRNAs are associated with DNA damage response pathway and senescence in inflammatory bowel disease. PLoS One. 2012;7(9):e44156. doi:10.1371/journal.pone.0044156.
    • (2012) PLoS One , vol.7 , Issue.9 , pp. 44156
    • Sohn, J.J.1    Schetter, A.J.2    Yfantis, H.G.3    Ridnour, L.A.4    Horikawa, I.5    Khan, M.A.6
  • 4
    • 84910132089 scopus 로고    scopus 로고
    • Predictors of response to anti-tumor necrosis factor therapy in ulcerative colitis
    • PID: 25133030
    • Zampeli E, Gizis M, Siakavellas SI, Bamias G. Predictors of response to anti-tumor necrosis factor therapy in ulcerative colitis. World J Gastrointest Pathophysiol. 2014;5(3):293–303. doi:10.4291/wjgp.v5.i3.293.
    • (2014) World J Gastrointest Pathophysiol , vol.5 , Issue.3 , pp. 293-303
    • Zampeli, E.1    Gizis, M.2    Siakavellas, S.I.3    Bamias, G.4
  • 5
    • 44349124113 scopus 로고    scopus 로고
    • The genetics and immunopathogenesis of inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BD1cXmt1Ojt7o%3D, PID: 18500230
    • Cho JH. The genetics and immunopathogenesis of inflammatory bowel disease. Nat Rev Immunol. 2008;8(6):458–66. doi:10.1038/nri2340.
    • (2008) Nat Rev Immunol , vol.8 , Issue.6 , pp. 458-466
    • Cho, J.H.1
  • 6
    • 84925486076 scopus 로고    scopus 로고
    • The gut microbiota and inflammatory bowel disease
    • PID: 25420450
    • Matsuoka K, Kanai T. The gut microbiota and inflammatory bowel disease. Semin Immunopathol. 2014;. doi:10.1007/s00281-014-0454-4.
    • (2014) Semin Immunopathol
    • Matsuoka, K.1    Kanai, T.2
  • 7
    • 84891804080 scopus 로고    scopus 로고
    • Immunopathology of inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BC2cXntVKqtrg%3D, PID: 24415853
    • Wallace KL, Zheng LB, Kanazawa Y, Shih DQ. Immunopathology of inflammatory bowel disease. WJG. 2014;20(1):6–21. doi:10.3748/wjg.v20.i1.6.
    • (2014) WJG , vol.20 , Issue.1 , pp. 6-21
    • Wallace, K.L.1    Zheng, L.B.2    Kanazawa, Y.3    Shih, D.Q.4
  • 8
    • 19444373939 scopus 로고    scopus 로고
    • Growth in epithelial cell proliferation and apoptosis correlates specifically to the inflammation activity of inflammatory bowel diseases: ulcerative colitis shows specific p53- and EGFR expression alterations
    • PID: 15747078
    • Sipos F, Molnar B, Zagoni T, Berczi L, Tulassay Z. Growth in epithelial cell proliferation and apoptosis correlates specifically to the inflammation activity of inflammatory bowel diseases: ulcerative colitis shows specific p53- and EGFR expression alterations. Dis Colon Rectum. 2005;48(4):775–86. doi:10.1007/s10350-004-0831-5.
    • (2005) Dis Colon Rectum , vol.48 , Issue.4 , pp. 775-786
    • Sipos, F.1    Molnar, B.2    Zagoni, T.3    Berczi, L.4    Tulassay, Z.5
  • 9
    • 84856940669 scopus 로고    scopus 로고
    • The life and death of epithelia during inflammation: lessons learned from the gut
    • COI: 1:CAS:528:DC%2BC38Xjs1KqsLk%3D
    • Koch S, Nusrat A. The life and death of epithelia during inflammation: lessons learned from the gut. Ann Rev Pathol. 2012;7:35–60. doi:10.1146/annurev-pathol-011811-120905.
    • (2012) Ann Rev Pathol , vol.7 , pp. 35-60
    • Koch, S.1    Nusrat, A.2
  • 10
    • 2942560318 scopus 로고    scopus 로고
    • Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86
    • COI: 1:CAS:528:DC%2BD2cXksFygsrw%3D, PID: 15075319
    • Wang H, Fang R, Cho JY, Libermann TA, Oettgen P. Positive and negative modulation of the transcriptional activity of the ETS factor ESE-1 through interaction with p300, CREB-binding protein, and Ku 70/86. J Biol Chem. 2004;279(24):25241–50. doi:10.1074/jbc.M401356200.
    • (2004) J Biol Chem , vol.279 , Issue.24 , pp. 25241-25250
    • Wang, H.1    Fang, R.2    Cho, J.Y.3    Libermann, T.A.4    Oettgen, P.5
  • 11
    • 11144357258 scopus 로고    scopus 로고
    • ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation
    • COI: 1:CAS:528:DC%2BD2cXitl2gtL0%3D, PID: 14715662
    • Brown C, Gaspar J, Pettit A, Lee R, Gu X, Wang H, et al. ESE-1 is a novel transcriptional mediator of angiopoietin-1 expression in the setting of inflammation. J Biol Chem. 2004;279(13):12794–803. doi:10.1074/jbc.M308593200.
    • (2004) J Biol Chem , vol.279 , Issue.13 , pp. 12794-12803
    • Brown, C.1    Gaspar, J.2    Pettit, A.3    Lee, R.4    Gu, X.5    Wang, H.6
  • 12
    • 0030839767 scopus 로고    scopus 로고
    • Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family
    • COI: 1:CAS:528:DyaK2sXkvVequ7c%3D, PID: 9234700
    • Oettgen P, Alani RM, Barcinski MA, Brown L, Akbarali Y, Boltax J, et al. Isolation and characterization of a novel epithelium-specific transcription factor, ESE-1, a member of the ets family. Mol Cell Biol. 1997;17(8):4419–33.
    • (1997) Mol Cell Biol , vol.17 , Issue.8 , pp. 4419-4433
    • Oettgen, P.1    Alani, R.M.2    Barcinski, M.A.3    Brown, L.4    Akbarali, Y.5    Boltax, J.6
  • 13
    • 9844246984 scopus 로고    scopus 로고
    • A novel epithelial-expressed ETS gene,, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer
    • COI: 1:CAS:528:DyaK2sXnsFajsLw%3D, PID: 9395241
    • Tymms MJ, Ng AY, Thomas RS, Schutte BC, Zhou J, Eyre HJ, et al. A novel epithelial-expressed ETS gene, ELF3: human and murine cDNA sequences, murine genomic organization, human mapping to 1q32.2 and expression in tissues and cancer. Oncogene. 1997;15(20):2449–62. doi:10.1038/sj.onc.1201427.
    • (1997) Oncogene , vol.15 , Issue.20 , pp. 2449-2462
    • Tymms, M.J.1    Ng, A.Y.2    Thomas, R.S.3    Schutte, B.C.4    Zhou, J.5    Eyre, H.J.6
  • 14
    • 84863287374 scopus 로고    scopus 로고
    • Multiple roles of the epithelium-specific ETS transcription factor, ESE-1, in development and disease
    • COI: 1:CAS:528:DC%2BC38XjtFOjur8%3D, PID: 22157719
    • Oliver JR, Kushwah R, Hu J. Multiple roles of the epithelium-specific ETS transcription factor, ESE-1, in development and disease. Lab Investig. 2012;92(3):320–30. doi:10.1038/labinvest.2011.186.
    • (2012) Lab Investig , vol.92 , Issue.3 , pp. 320-330
    • Oliver, J.R.1    Kushwah, R.2    Hu, J.3
  • 15
    • 27544515095 scopus 로고    scopus 로고
    • ETS transcription factors and their emerging roles in human cancer
    • COI: 1:CAS:528:DC%2BD2MXhtFyks73J, PID: 16213704
    • Seth A, Watson DK. ETS transcription factors and their emerging roles in human cancer. Eur J Cancer. 2005;41(16):2462–78. doi:10.1016/j.ejca.2005.08.013.
    • (2005) Eur J Cancer , vol.41 , Issue.16 , pp. 2462-2478
    • Seth, A.1    Watson, D.K.2
  • 16
    • 84893515646 scopus 로고    scopus 로고
    • Understanding the role of ETS-mediated gene regulation in complex biological processes
    • COI: 1:CAS:528:DC%2BC3sXhs1elt7vF, PID: 23870508
    • Findlay VJ, LaRue AC, Turner DP, Watson PM, Watson DK. Understanding the role of ETS-mediated gene regulation in complex biological processes. Adv Cancer Res. 2013;119:1–61. doi:10.1016/B978-0-12-407190-2.00001-0.
    • (2013) Adv Cancer Res , vol.119
    • Findlay, V.J.1    LaRue, A.C.2    Turner, D.P.3    Watson, P.M.4    Watson, D.K.5
  • 17
    • 0036142763 scopus 로고    scopus 로고
    • An ERK2 docking site in the pointed domain distinguishes a subset of ETS transcription factors
    • COI: 1:CAS:528:DC%2BD38Xos1egtg%3D%3D, PID: 11782450
    • Seidel JJ, Graves BJ. An ERK2 docking site in the pointed domain distinguishes a subset of ETS transcription factors. Genes Dev. 2002;16(1):127–37. doi:10.1101/gad.950902.
    • (2002) Genes Dev , vol.16 , Issue.1 , pp. 127-137
    • Seidel, J.J.1    Graves, B.J.2
  • 18
    • 0038691573 scopus 로고    scopus 로고
    • Interplay between proximal and distal promoter elements is required for squamous differentiation marker induction in the bronchial epithelium: role for ESE-1, Sp1, and AP-1 proteins
    • COI: 1:CAS:528:DC%2BD3sXksVenu78%3D, PID: 12682075
    • Reddy SP, Vuong H, Adiseshaiah P. Interplay between proximal and distal promoter elements is required for squamous differentiation marker induction in the bronchial epithelium: role for ESE-1, Sp1, and AP-1 proteins. J Biol Chem. 2003;278(24):21378–87. doi:10.1074/jbc.M212258200.
    • (2003) J Biol Chem , vol.278 , Issue.24 , pp. 21378-21387
    • Reddy, S.P.1    Vuong, H.2    Adiseshaiah, P.3
  • 19
    • 0035793609 scopus 로고    scopus 로고
    • ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene
    • COI: 1:CAS:528:DC%2BD3MXhtFWju7o%3D, PID: 11036073
    • Rudders S, Gaspar J, Madore R, Voland C, Grall F, Patel A, et al. ESE-1 is a novel transcriptional mediator of inflammation that interacts with NF-kappa B to regulate the inducible nitric-oxide synthase gene. J Biol Chem. 2001;276(5):3302–9. doi:10.1074/jbc.M006507200.
    • (2001) J Biol Chem , vol.276 , Issue.5 , pp. 3302-3309
    • Rudders, S.1    Gaspar, J.2    Madore, R.3    Voland, C.4    Grall, F.5    Patel, A.6
  • 20
    • 0343714574 scopus 로고    scopus 로고
    • Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation
    • COI: 1:CAS:528:DC%2BD3cXntF2qurw%3D, PID: 11025204
    • Yoshida N, Yoshida S, Araie M, Handa H, Nabeshima Y. Ets family transcription factor ESE-1 is expressed in corneal epithelial cells and is involved in their differentiation. Mech Dev. 2000;97(1–2):27–34.
    • (2000) Mech Dev , vol.97 , Issue.1-2 , pp. 27-34
    • Yoshida, N.1    Yoshida, S.2    Araie, M.3    Handa, H.4    Nabeshima, Y.5
  • 21
    • 84880894958 scopus 로고    scopus 로고
    • ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-kappaB and drives prostate cancer progression
    • COI: 1:CAS:528:DC%2BC3sXhtFSrtrbE, PID: 23687337
    • Longoni N, Sarti M, Albino D, Civenni G, Malek A, Ortelli E, et al. ETS transcription factor ESE1/ELF3 orchestrates a positive feedback loop that constitutively activates NF-kappaB and drives prostate cancer progression. Cancer Res. 2013;73(14):4533–47. doi:10.1158/0008-5472.CAN-12-4537.
    • (2013) Cancer Res , vol.73 , Issue.14 , pp. 4533-4547
    • Longoni, N.1    Sarti, M.2    Albino, D.3    Civenni, G.4    Malek, A.5    Ortelli, E.6
  • 22
    • 44849138714 scopus 로고    scopus 로고
    • Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation
    • COI: 1:CAS:528:DC%2BD1cXmsFegtLg%3D, PID: 18475289
    • Wu J, Duan R, Cao H, Field D, Newnham CM, Koehler DR, et al. Regulation of epithelium-specific Ets-like factors ESE-1 and ESE-3 in airway epithelial cells: potential roles in airway inflammation. Cell Res. 2008;18(6):649–63. doi:10.1038/cr.2008.57.
    • (2008) Cell Res , vol.18 , Issue.6 , pp. 649-663
    • Wu, J.1    Duan, R.2    Cao, H.3    Field, D.4    Newnham, C.M.5    Koehler, D.R.6
  • 23
    • 57749111001 scopus 로고    scopus 로고
    • ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells
    • COI: 1:CAS:528:DC%2BD1cXhsV2iurnL, PID: 19074849
    • Lee SH, Bahn JH, Choi CK, Whitlock NC, English AE, Safe S, et al. ESE-1/EGR-1 pathway plays a role in tolfenamic acid-induced apoptosis in colorectal cancer cells. Mol Cancer Ther. 2008;7(12):3739–50. doi:10.1158/1535-7163.MCT-08-0548.
    • (2008) Mol Cancer Ther , vol.7 , Issue.12 , pp. 3739-3750
    • Lee, S.H.1    Bahn, J.H.2    Choi, C.K.3    Whitlock, N.C.4    English, A.E.5    Safe, S.6
  • 24
    • 84870943584 scopus 로고    scopus 로고
    • Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation
    • COI: 1:CAS:528:DC%2BC38XpsFOktL4%3D, PID: 22763408
    • Koch S, Capaldo CT, Hilgarth RS, Fournier B, Parkos CA, Nusrat A. Protein kinase CK2 is a critical regulator of epithelial homeostasis in chronic intestinal inflammation. Mucosal Immunol. 2013;6(1):136–45. doi:10.1038/mi.2012.57.
    • (2013) Mucosal Immunol , vol.6 , Issue.1 , pp. 136-145
    • Koch, S.1    Capaldo, C.T.2    Hilgarth, R.S.3    Fournier, B.4    Parkos, C.A.5    Nusrat, A.6
  • 25
    • 77949937466 scopus 로고    scopus 로고
    • Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways
    • COI: 1:CAS:528:DC%2BC3cXlsVSntrk%3D, PID: 20303298
    • Nava P, Koch S, Laukoetter MG, Lee WY, Kolegraff K, Capaldo CT, et al. Interferon-gamma regulates intestinal epithelial homeostasis through converging beta-catenin signaling pathways. Immunity. 2010;32(3):392–402. doi:10.1016/j.immuni.2010.03.001.
    • (2010) Immunity , vol.32 , Issue.3 , pp. 392-402
    • Nava, P.1    Koch, S.2    Laukoetter, M.G.3    Lee, W.Y.4    Kolegraff, K.5    Capaldo, C.T.6
  • 26
    • 79959935078 scopus 로고    scopus 로고
    • Koch S, Nava P, Addis C, Kim W, Denning TL, Li L, et al. The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair. Gastroenterology. 2011;141(1):259-68, 68 e1-8
    • Koch S, Nava P, Addis C, Kim W, Denning TL, Li L, et al. The Wnt antagonist Dkk1 regulates intestinal epithelial homeostasis and wound repair. Gastroenterology. 2011;141(1):259-68, 68 e1-8. doi:10.1053/j.gastro.2011.03.043.
  • 27
    • 0028861975 scopus 로고
    • Antibodies to interleukin 12 abrogate established experimental colitis in mice
    • COI: 1:CAS:528:DyaK2MXovFWru7s%3D, PID: 7595199
    • Neurath MF, Fuss I, Kelsall BL, Stuber E, Strober W. Antibodies to interleukin 12 abrogate established experimental colitis in mice. J Exp Med. 1995;182(5):1281–90.
    • (1995) J Exp Med , vol.182 , Issue.5 , pp. 1281-1290
    • Neurath, M.F.1    Fuss, I.2    Kelsall, B.L.3    Stuber, E.4    Strober, W.5
  • 28
    • 84870568314 scopus 로고    scopus 로고
    • SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway
    • COI: 1:CAS:528:DC%2BC38XhvVClsr%2FJ, PID: 23051735
    • Liu Y, Chen Y, Lu X, Wang Y, Duan Y, Cheng C, et al. SCYL1BP1 modulates neurite outgrowth and regeneration by regulating the Mdm2/p53 pathway. Mol Biol Cell. 2012;23(23):4506–14. doi:10.1091/mbc.E12-05-0362.
    • (2012) Mol Biol Cell , vol.23 , Issue.23 , pp. 4506-4514
    • Liu, Y.1    Chen, Y.2    Lu, X.3    Wang, Y.4    Duan, Y.5    Cheng, C.6
  • 29
    • 0025181580 scopus 로고
    • A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice
    • COI: 1:STN:280:DyaK3c7ivVSnuw%3D%3D, PID: 1688816
    • Okayasu I, Hatakeyama S, Yamada M, Ohkusa T, Inagaki Y, Nakaya R. A novel method in the induction of reliable experimental acute and chronic ulcerative colitis in mice. Gastroenterology. 1990;98(3):694–702.
    • (1990) Gastroenterology , vol.98 , Issue.3 , pp. 694-702
    • Okayasu, I.1    Hatakeyama, S.2    Yamada, M.3    Ohkusa, T.4    Inagaki, Y.5    Nakaya, R.6
  • 30
    • 80455168387 scopus 로고    scopus 로고
    • CXCR4 antagonist AMD3100 modulates claudin expression and intestinal barrier function in experimental colitis
    • COI: 1:CAS:528:DC%2BC3MXhsFSrtL3J, PID: 22073304
    • Xia XM, Wang FY, Zhou J, Hu KF, Li SW, Zou BB. CXCR4 antagonist AMD3100 modulates claudin expression and intestinal barrier function in experimental colitis. PLoS ONE. 2011;6(11):e27282. doi:10.1371/journal.pone.0027282.
    • (2011) PLoS ONE , vol.6 , Issue.11 , pp. 27282
    • Xia, X.M.1    Wang, F.Y.2    Zhou, J.3    Hu, K.F.4    Li, S.W.5    Zou, B.B.6
  • 31
    • 2942594555 scopus 로고    scopus 로고
    • The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism
    • COI: 1:CAS:528:DC%2BD2cXkvFOqtbs%3D, PID: 15169914
    • Prescott JD, Koto KS, Singh M, Gutierrez-Hartmann A. The ETS transcription factor ESE-1 transforms MCF-12A human mammary epithelial cells via a novel cytoplasmic mechanism. Mol Cell Biol. 2004;24(12):5548–64. doi:10.1128/MCB.24.12.5548-5564.2004.
    • (2004) Mol Cell Biol , vol.24 , Issue.12 , pp. 5548-5564
    • Prescott, J.D.1    Koto, K.S.2    Singh, M.3    Gutierrez-Hartmann, A.4
  • 32
    • 79952278651 scopus 로고    scopus 로고
    • The counter-regulatory effects of ESE-1 during angiotensin II-mediated vascular inflammation and remodeling
    • COI: 1:CAS:528:DC%2BC3cXhsVagtbrI, PID: 20689519
    • Zhan Y, Yuan L, Kondo M, Oettgen P. The counter-regulatory effects of ESE-1 during angiotensin II-mediated vascular inflammation and remodeling. Am J Hypertens. 2010;23(12):1312–7. doi:10.1038/ajh.2010.164.
    • (2010) Am J Hypertens , vol.23 , Issue.12 , pp. 1312-1317
    • Zhan, Y.1    Yuan, L.2    Kondo, M.3    Oettgen, P.4
  • 33
    • 79955501236 scopus 로고    scopus 로고
    • PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice
    • COI: 1:CAS:528:DC%2BC3MXlvFKntrg%3D, PID: 21490394
    • Qiu W, Wu B, Wang X, Buchanan ME, Regueiro MD, Hartman DJ, et al. PUMA-mediated intestinal epithelial apoptosis contributes to ulcerative colitis in humans and mice. J Clin Investig. 2011;121(5):1722–32. doi:10.1172/JCI42917.
    • (2011) J Clin Investig , vol.121 , Issue.5 , pp. 1722-1732
    • Qiu, W.1    Wu, B.2    Wang, X.3    Buchanan, M.E.4    Regueiro, M.D.5    Hartman, D.J.6
  • 34
    • 0036678630 scopus 로고    scopus 로고
    • Anti-tumor necrosis factor treatment restores the gut barrier in Crohn’s disease
    • COI: 1:CAS:528:DC%2BD38XntVCjtLk%3D, PID: 12190167
    • Suenaert P, Bulteel V, Lemmens L, Noman M, Geypens B, Van Assche G, et al. Anti-tumor necrosis factor treatment restores the gut barrier in Crohn’s disease. Am J Gastroenterol. 2002;97(8):2000–4. doi:10.1111/j.1572-0241.2002.05914.x.
    • (2002) Am J Gastroenterol , vol.97 , Issue.8 , pp. 2000-2004
    • Suenaert, P.1    Bulteel, V.2    Lemmens, L.3    Noman, M.4    Geypens, B.5    Van Assche, G.6
  • 35
    • 0142053206 scopus 로고    scopus 로고
    • The immunological and genetic basis of inflammatory bowel disease
    • COI: 1:CAS:528:DC%2BD3sXls1Smtr4%3D, PID: 12876555
    • Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol. 2003;3(7):521–33. doi:10.1038/nri1132.
    • (2003) Nat Rev Immunol , vol.3 , Issue.7 , pp. 521-533
    • Bouma, G.1    Strober, W.2
  • 36
    • 0035893385 scopus 로고    scopus 로고
    • Kinase suppressor of Ras determines survival of intestinal epithelial cells exposed to tumor necrosis factor
    • COI: 1:CAS:528:DC%2BD38Xht1Ogtg%3D%3D, PID: 11751383
    • Yan F, John SK, Polk DB. Kinase suppressor of Ras determines survival of intestinal epithelial cells exposed to tumor necrosis factor. Cancer Res. 2001;61(24):8668–75.
    • (2001) Cancer Res , vol.61 , Issue.24 , pp. 8668-8675
    • Yan, F.1    John, S.K.2    Polk, D.B.3
  • 37
    • 67649216750 scopus 로고    scopus 로고
    • Groschwitz KR, Hogan SP. Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol. 2009;124(1):3–20; quiz 1–2
    • Groschwitz KR, Hogan SP. Intestinal barrier function: molecular regulation and disease pathogenesis. J Allergy Clin Immunol. 2009;124(1):3–20; quiz 1–2. doi:10.1016/j.jaci.2009.05.038.
  • 38
    • 84929711329 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced colitis increases NADPH oxidase 1 expression, oxidative stress, and neutrophil recruitment in the colon: preventive effect of apocynin
    • Mouzaoui S, Djerdjouri B, Makhezer N, Kroviarski Y, El-Benna J, Dang PM. Tumor necrosis factor-alpha-induced colitis increases NADPH oxidase 1 expression, oxidative stress, and neutrophil recruitment in the colon: preventive effect of apocynin. Mediat Inflamm. 2014;2014:312484. doi:10.1155/2014/312484.
    • (2014) Mediat Inflamm , vol.2014 , pp. 312484
    • Mouzaoui, S.1    Djerdjouri, B.2    Makhezer, N.3    Kroviarski, Y.4    El-Benna, J.5    Dang, P.M.6
  • 39
    • 0034745021 scopus 로고    scopus 로고
    • IKK beta is essential for protecting T cells from TNFalpha-induced apoptosis
    • COI: 1:CAS:528:DC%2BD3MXis1ehurw%3D, PID: 11290332
    • Senftleben U, Li ZW, Baud V, Karin M. IKK beta is essential for protecting T cells from TNFalpha-induced apoptosis. Immunity. 2001;14(3):217–30.
    • (2001) Immunity , vol.14 , Issue.3 , pp. 217-230
    • Senftleben, U.1    Li, Z.W.2    Baud, V.3    Karin, M.4
  • 40
    • 84906831870 scopus 로고    scopus 로고
    • NF-kappaB pathway in colitis-associated cancers
    • PID: 23626930
    • Viennois E, Chen F, Merlin D. NF-kappaB pathway in colitis-associated cancers. Transl Gastrointest Cancer. 2013;2(1):21–9. doi:10.3978/j.issn.2224-4778.2012.11.01.
    • (2013) Transl Gastrointest Cancer , vol.2 , Issue.1 , pp. 21-29
    • Viennois, E.1    Chen, F.2    Merlin, D.3
  • 41
    • 84878768244 scopus 로고    scopus 로고
    • Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium
    • PID: 22689519
    • Gunther C, Neumann H, Neurath MF, Becker C. Apoptosis, necrosis and necroptosis: cell death regulation in the intestinal epithelium. Gut. 2013;62(7):1062–71. doi:10.1136/gutjnl-2011-301364.
    • (2013) Gut , vol.62 , Issue.7 , pp. 1062-1071
    • Gunther, C.1    Neumann, H.2    Neurath, M.F.3    Becker, C.4
  • 42
    • 33645824969 scopus 로고    scopus 로고
    • Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed
    • COI: 1:CAS:528:DC%2BD28Xks1Sls7k%3D, PID: 16537969
    • Shen L, Turner JR. Role of epithelial cells in initiation and propagation of intestinal inflammation. Eliminating the static: tight junction dynamics exposed. Am J Physiol Gastrointest Liver Physiol. 2006;290(4):G577–82. doi:10.1152/ajpgi.00439.2005.
    • (2006) Am J Physiol Gastrointest Liver Physiol , vol.290 , Issue.4 , pp. 577-582
    • Shen, L.1    Turner, J.R.2
  • 43
    • 79960151246 scopus 로고    scopus 로고
    • Experimental study on the molecular mechanism of anthraquinone cathartics in inducing melanosis coli
    • PID: 21725878
    • Chen JY, Pan F, Zhang T, Xia J, Li YJ. Experimental study on the molecular mechanism of anthraquinone cathartics in inducing melanosis coli. Chin J Integr Med. 2011;17(7):525–30. doi:10.1007/s11655-011-0786-z.
    • (2011) Chin J Integr Med , vol.17 , Issue.7 , pp. 525-530
    • Chen, J.Y.1    Pan, F.2    Zhang, T.3    Xia, J.4    Li, Y.J.5
  • 44
    • 33646801637 scopus 로고    scopus 로고
    • Regulation of apoptosis during homeostasis and disease in the intestinal epithelium
    • PID: 16670531
    • Edelblum KL, Yan F, Yamaoka T, Polk DB. Regulation of apoptosis during homeostasis and disease in the intestinal epithelium. Inflamm Bowel Dis. 2006;12(5):413–24. doi:10.1097/01.MIB.0000217334.30689.3e.
    • (2006) Inflamm Bowel Dis , vol.12 , Issue.5 , pp. 413-424
    • Edelblum, K.L.1    Yan, F.2    Yamaoka, T.3    Polk, D.B.4
  • 45
    • 0036064749 scopus 로고    scopus 로고
    • Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery
    • PID: 12121505
    • Hagiwara C, Tanaka M, Kudo H. Increase in colorectal epithelial apoptotic cells in patients with ulcerative colitis ultimately requiring surgery. J Gastroenterol Hepatol. 2002;17(7):758–64.
    • (2002) J Gastroenterol Hepatol , vol.17 , Issue.7 , pp. 758-764
    • Hagiwara, C.1    Tanaka, M.2    Kudo, H.3
  • 46
    • 4344700784 scopus 로고    scopus 로고
    • Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor alpha antibody treatment
    • COI: 1:CAS:528:DC%2BD2cXnvVyisbY%3D, PID: 15306588
    • Zeissig S, Bojarski C, Buergel N, Mankertz J, Zeitz M, Fromm M, et al. Downregulation of epithelial apoptosis and barrier repair in active Crohn’s disease by tumour necrosis factor alpha antibody treatment. Gut. 2004;53(9):1295–302. doi:10.1136/gut.2003.036632.
    • (2004) Gut , vol.53 , Issue.9 , pp. 1295-1302
    • Zeissig, S.1    Bojarski, C.2    Buergel, N.3    Mankertz, J.4    Zeitz, M.5    Fromm, M.6
  • 47
    • 0038153911 scopus 로고    scopus 로고
    • TNF-alpha neutralization ameliorates the severity of murine Crohn’s-like ileitis by abrogation of intestinal epithelial cell apoptosis
    • COI: 1:CAS:528:DC%2BD3sXlsFGnt7Y%3D, PID: 12832622
    • Marini M, Bamias G, Rivera-Nieves J, Moskaluk CA, Hoang SB, Ross WG, et al. TNF-alpha neutralization ameliorates the severity of murine Crohn’s-like ileitis by abrogation of intestinal epithelial cell apoptosis. Proc Natl Acad Sci USA. 2003;100(14):8366–71. doi:10.1073/pnas.1432897100.
    • (2003) Proc Natl Acad Sci USA , vol.100 , Issue.14 , pp. 8366-8371
    • Marini, M.1    Bamias, G.2    Rivera-Nieves, J.3    Moskaluk, C.A.4    Hoang, S.B.5    Ross, W.G.6
  • 48
    • 0031982581 scopus 로고    scopus 로고
    • A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-beta type II receptor
    • COI: 1:CAS:528:DyaK1cXjvFSiuw%3D%3D, PID: 9417054
    • Choi SG, Yi Y, Kim YS, Kato M, Chang J, Chung HW, et al. A novel ets-related transcription factor, ERT/ESX/ESE-1, regulates expression of the transforming growth factor-beta type II receptor. J Biol Chem. 1998;273(1):110–7.
    • (1998) J Biol Chem , vol.273 , Issue.1 , pp. 110-117
    • Choi, S.G.1    Yi, Y.2    Kim, Y.S.3    Kato, M.4    Chang, J.5    Chung, H.W.6
  • 49
    • 8244259923 scopus 로고    scopus 로고
    • ESX: a structurally unique Ets overexpressed early during human breast tumorigenesis
    • COI: 1:CAS:528:DyaK2sXislKltLk%3D, PID: 9129154
    • Chang CH, Scott GK, Kuo WL, Xiong X, Suzdaltseva Y, Park JW, et al. ESX: a structurally unique Ets overexpressed early during human breast tumorigenesis. Oncogene. 1997;14(13):1617–22. doi:10.1038/sj.onc.1200978.
    • (1997) Oncogene , vol.14 , Issue.13 , pp. 1617-1622
    • Chang, C.H.1    Scott, G.K.2    Kuo, W.L.3    Xiong, X.4    Suzdaltseva, Y.5    Park, J.W.6
  • 50
    • 0036235357 scopus 로고    scopus 로고
    • Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium
    • COI: 1:CAS:528:DC%2BD38Xkt1Cqsr8%3D, PID: 11984530
    • Ng AY, Waring P, Ristevski S, Wang C, Wilson T, Pritchard M, et al. Inactivation of the transcription factor Elf3 in mice results in dysmorphogenesis and altered differentiation of intestinal epithelium. Gastroenterology. 2002;122(5):1455–66.
    • (2002) Gastroenterology , vol.122 , Issue.5 , pp. 1455-1466
    • Ng, A.Y.1    Waring, P.2    Ristevski, S.3    Wang, C.4    Wilson, T.5    Pritchard, M.6
  • 51
    • 0034611596 scopus 로고    scopus 로고
    • Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation
    • COI: 1:CAS:528:DC%2BD3cXjtV2qu7o%3D, PID: 10773884
    • Brembeck FH, Opitz OG, Libermann TA, Rustgi AK. Dual function of the epithelial specific ets transcription factor, ELF3, in modulating differentiation. Oncogene. 2000;19(15):1941–9. doi:10.1038/sj.onc.1203441.
    • (2000) Oncogene , vol.19 , Issue.15 , pp. 1941-1949
    • Brembeck, F.H.1    Opitz, O.G.2    Libermann, T.A.3    Rustgi, A.K.4
  • 52
    • 84883226491 scopus 로고    scopus 로고
    • Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29
    • COI: 1:CAS:528:DC%2BC3sXhsVahsLzP, PID: 23941773
    • Lee SY, Debnath T, Kim SK, Lim BO. Anti-cancer effect and apoptosis induction of cordycepin through DR3 pathway in the human colonic cancer cell HT-29. Food Chem Toxicol. 2013;60:439–47. doi:10.1016/j.fct.2013.07.068.
    • (2013) Food Chem Toxicol , vol.60 , pp. 439-447
    • Lee, S.Y.1    Debnath, T.2    Kim, S.K.3    Lim, B.O.4
  • 53
    • 84924161429 scopus 로고    scopus 로고
    • Khz (Fusion Product of Ganoderma lucidum and Polyporus umbellatus Mycelia) Induces apoptosis in human colon carcinoma HCT116 cells, accompanied by an increase in reactive oxygen species, activation of caspase 3, and increased intracellular Ca
    • Kim TH, Kim JS, Kim ZH, Huang RB, Chae YL, Wang RS. Khz (Fusion Product of Ganoderma lucidum and Polyporus umbellatus Mycelia) Induces apoptosis in human colon carcinoma HCT116 cells, accompanied by an increase in reactive oxygen species, activation of caspase 3, and increased intracellular Ca. J Med Food. 2014;. doi:10.1089/jmf.2013.3135.
    • (2014) J Med Food
    • Kim, T.H.1    Kim, J.S.2    Kim, Z.H.3    Huang, R.B.4    Chae, Y.L.5    Wang, R.S.6
  • 54
    • 0037653338 scopus 로고    scopus 로고
    • Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1
    • COI: 1:CAS:528:DC%2BD3sXkt1aksbY%3D, PID: 12746898
    • Grall F, Gu X, Tan L, Cho JY, Inan MS, Pettit AR, et al. Responses to the proinflammatory cytokines interleukin-1 and tumor necrosis factor alpha in cells derived from rheumatoid synovium and other joint tissues involve nuclear factor kappaB-mediated induction of the Ets transcription factor ESE-1. Arthritis Rheum. 2003;48(5):1249–60. doi:10.1002/art.10942.
    • (2003) Arthritis Rheum , vol.48 , Issue.5 , pp. 1249-1260
    • Grall, F.1    Gu, X.2    Tan, L.3    Cho, J.Y.4    Inan, M.S.5    Pettit, A.R.6
  • 55
    • 67650330166 scopus 로고    scopus 로고
    • Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer
    • COI: 1:CAS:528:DC%2BD1MXmsFWru7k%3D, PID: 19404270
    • Feagins LA, Souza RF, Spechler SJ. Carcinogenesis in IBD: potential targets for the prevention of colorectal cancer. Nat Rev Gastroenterol Hepatol. 2009;6(5):297–305. doi:10.1038/nrgastro.2009.44.
    • (2009) Nat Rev Gastroenterol Hepatol , vol.6 , Issue.5 , pp. 297-305
    • Feagins, L.A.1    Souza, R.F.2    Spechler, S.J.3


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