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Volumn 194, Issue 11, 2015, Pages 5129-5138

Anti-factor H autoantibodies in C3 glomerulopathies and in atypical hemolytic uremic syndrome: One target, two diseases

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; AUTOANTIBODY; COMPLEMENT COMPONENT C4; COMPLEMENT FACTOR H; COMPLEMENT FACTOR I; FACTOR H AUTOANTIBODY; IMMUNOGLOBULIN G ANTIBODY; NEPHRITIC FACTOR; UNCLASSIFIED DRUG; CFHR1 PROTEIN, HUMAN; CFHR3 PROTEIN, HUMAN; IMMUNOGLOBULIN G; PLASMA PROTEIN;

EID: 84929629467     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402770     Document Type: Article
Times cited : (94)

References (52)
  • 2
    • 67649230210 scopus 로고    scopus 로고
    • Structure of complement fragment C3b-factor H and implications for host protection by complement regulators
    • Wu, J., Y. Q. Wu, D. Ricklin, B. J. Janssen, J. D. Lambris, and P. Gros. 2009. Structure of complement fragment C3b-factor H and implications for host protection by complement regulators. Nat. Immunol. 10: 728-733.
    • (2009) Nat. Immunol , vol.10 , pp. 728-733
    • Wu, J.1    Wu, Y.Q.2    Ricklin, D.3    Janssen, B.J.4    Lambris, J.D.5    Gros, P.6
  • 4
    • 77952322658 scopus 로고    scopus 로고
    • Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d
    • Bhattacharjee, A., M. J. Lehtinen, T. Kajander, A. Goldman, and T. S. Jokiranta. 2010. Both domain 19 and domain 20 of factor H are involved in binding to complement C3b and C3d. Mol. Immunol. 47: 1686-1691.
    • (2010) Mol. Immunol , vol.47 , pp. 1686-1691
    • Bhattacharjee, A.1    Lehtinen, M.J.2    Kajander, T.3    Goldman, A.4    Jokiranta, T.S.5
  • 11
    • 84858668780 scopus 로고    scopus 로고
    • Membranoproliferative glomerulonephritis - A new look at an old entity
    • Sethi, S., and F. C. Fervenza. 2012. Membranoproliferative glomerulonephritis -a new look at an old entity. N. Engl. J. Med. 366: 1119-1131.
    • (2012) N. Engl. J. Med , vol.366 , pp. 1119-1131
    • Sethi, S.1    Fervenza, F.C.2
  • 14
    • 70350279315 scopus 로고    scopus 로고
    • Atypical hemolytic-uremic syndrome
    • Noris, M., and G. Remuzzi. 2009. Atypical hemolytic-uremic syndrome. N. Engl. J. Med. 361: 1676-1687.
    • (2009) N. Engl. J. Med , vol.361 , pp. 1676-1687
    • Noris, M.1    Remuzzi, G.2
  • 15
    • 1542318912 scopus 로고    scopus 로고
    • Heterozygous and homozygous factor H deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: Report and genetic analysis of 16 cases
    • Dragon-Durey, M. A., V. Frémeaux-Bacchi, C. Loirat, J. Blouin, P. Niaudet, G. Deschenes, P. Coppo, W. Herman Fridman, and L. Weiss. 2004. Heterozygous and homozygous factor H deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 cases. J. Am. Soc. Nephrol. 15: 787-795.
    • (2004) J. Am. Soc. Nephrol , vol.15 , pp. 787-795
    • Dragon-Durey, M.A.1    Frémeaux-Bacchi, V.2    Loirat, C.3    Blouin, J.4    Niaudet, P.5    Deschenes, G.6    Coppo, P.7    Herman Fridman, W.8    Weiss, L.9
  • 19
    • 76949087440 scopus 로고    scopus 로고
    • Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome
    • Abarrategui-Garrido, C., R. Martínez-Barricarte, M. López-Trascasa, S. R. de Córdoba, and P. Sánchez-Corral. 2009. Characterization of complement factor H-related (CFHR) proteins in plasma reveals novel genetic variations of CFHR1 associated with atypical hemolytic uremic syndrome. Blood 114: 4261-4271.
    • (2009) Blood , vol.114 , pp. 4261-4271
    • Abarrategui-Garrido, C.1    Martínez-Barricarte, R.2    López-Trascasa, M.3    De Córdoba, S.R.4    Sánchez-Corral, P.5
  • 20
    • 34548853385 scopus 로고    scopus 로고
    • Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome
    • Józsi, M., S. Strobel, H. M. Dahse,W. S. Liu, P. F. Hoyer, M. Oppermann, C. Skerka, and P. F. Zipfel. 2007. Anti factor H autoantibodies block C-terminal recognition function of factor H in hemolytic uremic syndrome. Blood 110: 1516-1518.
    • (2007) Blood , vol.110 , pp. 1516-1518
    • Józsi, M.1    Strobel, S.2    Dahsew. S Liu, H.M.3    Hoyer, P.F.4    Oppermann, M.5    Skerka, C.6    Zipfel, P.F.7
  • 22
    • 84899769165 scopus 로고    scopus 로고
    • Prompt plasma exchanges and immunosuppressive treatment improves the outcomes of anti-factor H autoantibody-associated hemolytic uremic syndrome in children
    • Indian HUS Registry
    • Sinha, A., A. Gulati, S. Saini, C. Blanc, A. Gupta, B. S. Gurjar, H. Saini, S. T. Kotresh, U. Ali, D. Bhatia, et al; Indian HUS Registry. 2014. Prompt plasma exchanges and immunosuppressive treatment improves the outcomes of anti-factor H autoantibody-associated hemolytic uremic syndrome in children. Kidney Int. 85: 1151-1160.
    • (2014) Kidney Int , vol.85 , pp. 1151-1160
    • Sinha, A.1    Gulati, A.2    Saini, S.3    Blanc, C.4    Gupta, A.5    Gurjar, B.S.6    Saini, H.7    Kotresh, S.T.8    Ali, U.9    Bhatia, D.10
  • 23
    • 75649133611 scopus 로고    scopus 로고
    • Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome
    • Moore, I., L. Strain, I. Pappworth, D. Kavanagh, P. N. Barlow, A. P. Herbert, C. Q. Schmidt, S. J. Staniforth, L. V. Holmes, R. Ward, et al. 2010. Association of factor H autoantibodies with deletions of CFHR1, CFHR3, CFHR4, and with mutations in CFH, CFI, CD46, and C3 in patients with atypical hemolytic uremic syndrome. Blood 115: 379-387.
    • (2010) Blood , vol.115 , pp. 379-387
    • Moore, I.1    Strain, L.2    Pappworth, I.3    Kavanagh, D.4    Barlow, P.N.5    Herbert, A.P.6    Schmidt, C.Q.7    Staniforth, S.J.8    Holmes, L.V.9    Ward, R.10
  • 24
    • 38949155911 scopus 로고    scopus 로고
    • Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency
    • Józsi, M., C. Licht, S. Strobel, S. L. Zipfel, H. Richter, S. Heinen, P. F. Zipfel, and C. Skerka. 2008. Factor H autoantibodies in atypical hemolytic uremic syndrome correlate with CFHR1/CFHR3 deficiency. Blood 111: 1512-1514.
    • (2008) Blood , vol.111 , pp. 1512-1514
    • Józsi, M.1    Licht, C.2    Strobel, S.3    Zipfel, S.L.4    Richter, H.5    Heinen, S.6    Zipfel, P.F.7    Skerka, C.8
  • 25
    • 34047200899 scopus 로고    scopus 로고
    • Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome
    • Zipfel, P. F., M. Edey, S. Heinen, M. Józsi, H. Richter, J. Misselwitz, B. Hoppe, D. Routledge, L. Strain, A. E. Hughes, et al. 2007. Deletion of complement factor H-related genes CFHR1 and CFHR3 is associated with atypical hemolytic uremic syndrome. PLoS Genet. 3: e41. Available at: http://journals.plos.org/ plosgenetics/article?id=10.1371/journal.pgen.0030041.
    • (2007) PLoS Genet , vol.3 , pp. e41
    • Zipfel, P.F.1    Edey, M.2    Heinen, S.3    Józsi, M.4    Richter, H.5    Misselwitz, J.6    Hoppe, B.7    Routledge, D.8    Strain, L.9    Hughes, A.E.10
  • 26
    • 67650508077 scopus 로고    scopus 로고
    • The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome
    • Dragon-Durey, M. A., C. Blanc, F. Marliot, C. Loirat, J. Blouin, C. Sautes-Fridman, W. H. Fridman, and V. Frémeaux-Bacchi. 2009. The high frequency of complement factor H related CFHR1 gene deletion is restricted to specific subgroups of patients with atypical haemolytic uraemic syndrome. J. Med. Genet. 46: 447-450.
    • (2009) J. Med. Genet , vol.46 , pp. 447-450
    • Dragon-Durey, M.A.1    Blanc, C.2    Marliot, F.3    Loirat, C.4    Blouin, J.5    Sautes-Fridman, C.6    Fridman, W.H.7    Frémeaux-Bacchi, V.8
  • 28
    • 84866556872 scopus 로고    scopus 로고
    • Overall neutralization of complement factor H by autoantibodies in the acute phase of the autoimmune form of atypical hemolytic uremic syndrome
    • Blanc, C., L. T. Roumenina, Y. Ashraf, S. Hyvärinen, S. K. Sethi, B. Ranchin, P. Niaudet, C. Loirat, A. Gulati, A. Bagga, et al. 2012. Overall neutralization of complement factor H by autoantibodies in the acute phase of the autoimmune form of atypical hemolytic uremic syndrome. J. Immunol. 189: 3528-3537.
    • (2012) J. Immunol , vol.189 , pp. 3528-3537
    • Blanc, C.1    Roumenina, L.T.2    Ashraf, Y.3    Hyvärinen, S.4    Sethi, S.K.5    Ranchin, B.6    Niaudet, P.7    Loirat, C.8    Gulati, A.9    Bagga, A.10
  • 29
    • 0032875669 scopus 로고    scopus 로고
    • Nephritogenic lambda light chain dimer: A unique human miniautoantibody against complement factor H
    • Jokiranta, T. S., A. Solomon, M. K. Pangburn, P. F. Zipfel, and S. Meri. 1999. Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor H. J. Immunol. 163: 4590-4596.
    • (1999) J. Immunol , vol.163 , pp. 4590-4596
    • Jokiranta, T.S.1    Solomon, A.2    Pangburn, M.K.3    Zipfel, P.F.4    Meri, S.5
  • 30
    • 0026549476 scopus 로고
    • Activation of the alternative pathway of complement by monoclonal lambda light chains in membranoproliferative glomerulonephritis
    • Meri, S., V. Koistinen, A. Miettinen, T. Törnroth, and I. J. Seppälä. 1992. Activation of the alternative pathway of complement by monoclonal lambda light chains in membranoproliferative glomerulonephritis. J. Exp. Med. 175: 939-950.
    • (1992) J. Exp. Med , vol.175 , pp. 939-950
    • Meri, S.1    Koistinen, V.2    Miettinen, A.3    Törnroth, T.4    Seppälä, I.J.5
  • 38
    • 2342582709 scopus 로고    scopus 로고
    • Functional analysis in serum from atypical hemolytic uremic syndrome patients reveals impaired protection of host cells associated with mutations in factor H
    • Sánchez-Corral, P., C. González-Rubio, S. Rodríguez de Córdoba, and M. López-Trascasa. 2004. Functional analysis in serum from atypical hemolytic uremic syndrome patients reveals impaired protection of host cells associated with mutations in factor H. Mol. Immunol. 41: 81-84.
    • (2004) Mol. Immunol , vol.41 , pp. 81-84
    • Sánchez-Corral, P.1    González-Rubio, C.2    Rodríguez De Córdoba, S.3    López-Trascasa, M.4
  • 39
    • 84934443927 scopus 로고    scopus 로고
    • Functional evaluation of factor H genetic and acquired abnormalities: Application for atypical hemolytic uremic syndrome (aHUS)
    • Roumenina, L. T., R. Roquigny, C. Blanc, N. Poulain, S. Ngo, M. A. Dragon-Durey, and V. Frémeaux-Bacchi. 2014. Functional evaluation of factor H genetic and acquired abnormalities: application for atypical hemolytic uremic syndrome (aHUS). Methods Mol. Biol. 1100: 237-247.
    • (2014) Methods Mol. Biol , vol.1100 , pp. 237-247
    • Roumenina, L.T.1    Roquigny, R.2    Blanc, C.3    Poulain, N.4    Ngo, S.5    Dragon-Durey, M.A.6    Frémeaux-Bacchi, V.7
  • 40
    • 0036890316 scopus 로고    scopus 로고
    • Electrostatics in protein binding and function
    • Sinha, N., and S. J. Smith-Gill. 2002. Electrostatics in protein binding and function. Curr. Protein Pept. Sci. 3: 601-614.
    • (2002) Curr. Protein Pept. Sci , vol.3 , pp. 601-614
    • Sinha, N.1    Smith-Gill, S.J.2
  • 41
    • 0038103565 scopus 로고    scopus 로고
    • X-ray snapshots of the maturation of an antibody response to a protein antigen
    • Li, Y., H. Li, F. Yang, S. J. Smith-Gill, and R. A. Mariuzza. 2003. X-ray snapshots of the maturation of an antibody response to a protein antigen. Nat. Struct. Biol. 10: 482-488.
    • (2003) Nat. Struct. Biol , vol.10 , pp. 482-488
    • Li, Y.1    Li, H.2    Yang, F.3    Smith-Gill, S.J.4    Mariuzza, R.A.5
  • 42
  • 44
    • 79953190798 scopus 로고    scopus 로고
    • Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities
    • Pechtl, I. C., D. Kavanagh, N. McIntosh, C. L. Harris, and P. N. Barlow. 2011. Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activities. J. Biol. Chem. 286: 11082-11090.
    • (2011) J. Biol. Chem , vol.286 , pp. 11082-11090
    • Pechtl, I.C.1    Kavanagh, D.2    McIntosh, N.3    Harris, C.L.4    Barlow, P.N.5
  • 45
    • 84855282981 scopus 로고    scopus 로고
    • Complement factor H-ligand interactions: Self-association, multivalency and dissociation constants
    • Perkins, S. J., R. Nan, K. Li, S. Khan, and A. Miller. 2012. Complement factor H-ligand interactions: self-association, multivalency and dissociation constants. Immunobiology 217: 281-297.
    • (2012) Immunobiology , vol.217 , pp. 281-297
    • Perkins, S.J.1    Nan, R.2    Li, K.3    Khan, S.4    Miller, A.5
  • 46
    • 58149336975 scopus 로고    scopus 로고
    • Complement factor H: Using atomic resolution structure to illuminate disease mechanisms
    • Barlow, P. N.,G. S. Hageman, and S.M. Lea. 2008. Complement factor H: using atomic resolution structure to illuminate disease mechanisms. Adv. Exp. Med. Biol. 632: 117-142.
    • (2008) Adv. Exp. Med. Biol , vol.632 , pp. 117-142
    • Barlow, P.N.1    Hageman, G.S.2    Lea, S.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.