Hesperidin Supplementation Modulates Inflammatory Responses Following Myocardial Infarction

Journal of the American College of Nutrition

Volumn 34, Issue 3, 2015, Pages 205-211

  Haidari, F ^a   Heybar, H ^a   Jalali, M T ^a   Ahmadi Engali, K ^a   Helli, B ^a   Shirbeigi, E ^a  

^a AHVAZ JUNDISHAPUR UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

flavonoids; hesperidin; inflammation; lipid profile; myocardial infarction

Indexed keywords

ADIPOCYTOKINE; ADIPONECTIN; C REACTIVE PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; HESPERIDIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INTERLEUKIN 6; LEPTIN; PLACEBO; BIOLOGICAL MARKER; IL6 PROTEIN, HUMAN;

ADULT; ARTICLE; BIOCHEMICAL ANALYSIS; BLOOD SAMPLING; CONTROLLED STUDY; DIETARY INTAKE; DOUBLE BLIND PROCEDURE; ENZYME LINKED IMMUNOSORBENT ASSAY; HEART INFARCTION; HUMAN; INFLAMMATION; LIPID ANALYSIS; MAJOR CLINICAL STUDY; RANDOMIZED CONTROLLED TRIAL; BLOOD; COMPLICATION; DIET SUPPLEMENTATION; FEMALE; MALE; MIDDLE AGED;

CITRUS;

ADIPOKINES; ADIPONECTIN; ADULT; BIOMARKERS; C-REACTIVE PROTEIN; CHOLESTEROL, HDL; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; E-SELECTIN; FEMALE; HESPERIDIN; HUMANS; INFLAMMATION; INTERLEUKIN-6; LEPTIN; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PLACEBOS;

EID: 84929607224     PISSN: 07315724     EISSN: 15411087     Source Type: Journal    
DOI: 10.1080/07315724.2014.891269     Document Type: Article

References (30)

1. D.M.Tehrani, A.H.Seto: Third universal definition of myocardial infarction: update, caveats, differential diagnoses. Cleve Clin J Med 80:777–786, 2013.
2. G.D.Ghuge, R.Zine, M.R.Mogrekar: High sensitivity C-reactive protein, paraxonase 1 and high density lipoprotein cholesterol in myocardial infarction. Int J Biomed Adv Res 3:637–639, 2012.
3. H.Suefuji, H.Ogawa, H.Yasue, T.Sakamoto, Y.Miyao, K.Kaikita, Soejima H, Misumi K, Miyamoto S, Kataoka K: Increased plasma level of soluble E-selectin in acute myocardial infarction. Am Heart J 140:243–248, 2000.
4. M.Shojaie, A.Sotoodah, G.Shafaie: Is Adiponectin associated with acute myocardial infarction in Iranian non obese patients? Lipids Health Dis 28:8–17, 2009.
5. M.Ambroziak, Z.Bartoszewicz, A.Budaj: Total and high molecular weight adiponectin are decreased in young patients with myocardial infarction. J Am Coll Cardiol 59:E530–E530, 2012.
6. B.Gustafson: Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb 17:332–341, 2010.
7. S.Akram, Z.Ahmed, I.Fayyaz, S.Mehmood, M.Ghani, A.M.Choudhary, Shah I: Serum leptin levels in patients with coronary artery disease. J Ayub Med Coll Abbottabad 23:13–14, 2011.
8. S.W.Kim, C.E.Kim, M.H.Kim: Flavonoids inhibit high glucose-induced up-regulation of ICAM-1 via the p38 MAPK pathway in human vein endothelial cells. Biochem Biophys Res Commun 415:602–607, 2011.
9. C.Morand, C.Dubray, D.Milenkovic, D.Lioger, J.F.Martin, A.Scalbert, Mazur A: Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers. Am J Clin Nutr 93:73–80, 2011.
10. S.S.Raza, M.M.Khan, A.Ahmad, M.Ashafaq, G.Khuwaja, R.Tabassum, Javed H, Siddiqui MS, Safhi MM, Isalam F: Hesperidin ameliorates functional and histological outcome and reduces neuroinflammation in experimental stroke. Brain Res 1420:93–105, 2011.
11. F.Haidari, S.A.Keshavarz, M.R.Rashidi, M.Mohammad Shahi: Orange juice and hesperetin supplementation to hyperuricemic rats alter oxidative stress markers and xanthine oxidoreductase activity. J Clin Biochem Nutr 45:285–291, 2009.
12. F.Haidari, M.R.Rashidi, M.Mohammad Shahi: Effects of orange juice and hesperetin on serum paraxonase activity and lipid profile in hyperuricemic rats. BioImpacts 2:39–45, 2012.
13. B.D.Sahu, M.Kuncha, G.J.Sindhura, R.Sistla: Hesperidin attenuates cisplatin-induced acute renal injury by decreasing oxidative stress, inflammation and DNA damage. Phytomedicine 20:453–460, 2013.
14. K.Y.Wolin, D.P.Heil, S.Askew, C.E.Matthews, G.G.Bennett: Validation of the International Physical Activity Questionnaire–Short among blacks. J Phys Act Health 5:746–760, 2008.
15. X.Wang, J.Hasegawa, Y.Kitamura, Z.Wang, A.Matsuda, W.Shinoda, Miura N, Kimura K: Effects of hesperidin on the progression of hypercholesterolemia and fatty liver induced by high-cholesterol diet in rats. J Pharmacol Sci 117:129–138, 2011.
16. A.Yasim, D.Ozbag, M.Kilinc, H.Ciralik, I.Toru: The effects of diosmin–hesperidin combination treatment on the lipid profile and oxidative–antioxidative system in high-cholesterol diet-fed rats. Türk Göğüs Kalp Damar Cer Derg 19:55–61, 2011.
17. S.Akiyama, S.Katsumata, K.Suzuki, Y.Ishimi, J.Wu, M.Uehara: Dietary hesperidin exerts hypoglycemic and hypolipidemic effects in streptozotocin-induced marginal type 1 diabetic rats. J Clin Biochem Nutr 46:87–92, 2010.
18. S.Akiyama, S.Katsumata, K.Suzuki, Y.Nakaya, Y.Ishimi, M.Uehara: Hypoglycemic and hypolipidemic effects of hesperidin and cyclodextrin-clathrated hesperetin in Goto-Kakizaki rats with type 2 diabetes. Biosci Biotechnol Biochem 73:2779–2782, 2009.
19. S.Rizza, R.Muniyappa, M.Iantorno, J.A.Kim, H.Chen, P.Pullikotil, Senese N, Tesauro M, Lauro D, Cardillo C, Quon MJ: Citrus polyphenol hesperidin stimulates production of nitric oxide in endothelial cells while improving endothelial function and reducing inflammatory markers in patients with metabolic syndrome. J Clin Endocrinol Metab 96:E782–E792, 2011.
20. A.Ala, A.P.Dhillon, H.J.Hodgson: Role of cell adhesion molecules in leukocyte recruitment in the liver and gut. Int J Exp Pathol 84:1–16, 2003.
21. H.Suefuji, H.Ogawa, H.Yasue, T.Sakamoto, Y.Miyao, K.Kaikita, Soejima H, Misumi K, Miyamoto S, Kataoka K: Increased plasma level of soluble E-selectin in acute myocardial infarction. Am Heart J 140:243–248, 2000.
22. K.Piestrzeniewicz, K.Luczak, J.Komorowski, M.Maciejewski, M.Piechowiak, J.Jankiewicz-Wika, Goch JH: Obesity and adiponectin in acute myocardial infarction. Cardiol J 14:29–36, 2007.
23. E.M.Kurowska, J.D.Spence, J.Jordan, S.Wetmore, D.J.Freeman, L.A.Piché, Serratore P: HDL-cholesterol-raising effect of orange juice in subjects with hypercholesterolemia. Am J Clin Nutr 72:1095–1100, 2000.
24. T.B.Cesar, N.P.Aptekmann, M.P.Araujo, C.C.Vinagre, R.C.Maranhão: Orange juice decreases low-density lipoprotein cholesterol in hypercholesterolemic subjects and improves lipid transfer to high-density lipoprotein in normal and hypercholesterolemic subjects. Nutr Res 30:689–694, 2010.
25. Y.Miwa, M.Yamada, T.Sunayama, H.Mitsuzumi, Y.Tsuzaki, H.Chaen, Mishima Y, Kibata M: Effects of glucosyl hesperidin on serum lipids in hyperlipidemic subjects: preferential reduction in elevated serum triglyceride level. J Nutr Sci Vitaminol (Tokyo) 50:211–218, 2004.
26. I.Demonty, Y.Lin, Y.E.Zebregs, M.A.Vermeer, H.C.van der Knaap, M.Jäkel, Trautwein EA: The citrus flavonoids hesperidin and naringin do not affect serum cholesterol in moderately hypercholesterolemic men and women. J Nutr 140:1615–1620, 2010.
27. H.J.Kim, S.M.Jeon, M.K.Lee, Y.Y.Cho, E.Y.Kwon, J.H.Lee, Choi MS: Comparison of hesperetin and its metabolites for cholesterol-lowering and antioxidative efficacy in hypercholesterolemic hamsters. J Med Food 13:808–814, 2010.
28. A.S.Antonopoulos, M.Margaritis, R.Lee, K.Channon, C.Antoniades: Statins as anti-inflammatory agents in atherogenesis: molecular mechanisms and lessons from the recent clinical trials. Curr Pharm Des 18:1519–1530, 2012.
29. D.Grassi, G.Desideri, G.Croce, S.Tiberti, A.Aggio, C.Ferri: Flavonoids, vascular function and cardiovascular protection. Curr Pharm Des 15:1072–1084, 2009.
30. L.Actis-Goretta, J.I.Ottaviani, C.G.Fraga: Inhibition of angiotensin converting enzyme activity by flavanol-rich foods. J Agr Food Chem 54:229–234, 2006.