Engineering Escherichia coli into a Protein Delivery System for Mammalian Cells

ACS Synthetic Biology

Volumn 4, Issue 5, 2015, Pages 644-654

  Reeves, Analise Z ^a,b   Spears, William E ^a   Du, Juan ^a,b   Tan, Kah Yong ^c,d,e   Wagers, Amy J ^c,d,e   Lesser, Cammie F ^a,b,d  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c Harvard University   (United States)

^d HARVARD STEM CELL INSTITUTE   (United States)

^e JOSLIN DIABETES CENTER   (United States)

Author keywords

bacterial engineering; protein delivery; synthetic biology; type 3 secretion system

Indexed keywords

BACTERIAL DNA; CHAPERONE; MYOD PROTEIN; VIRB PROTEIN; BACTERIAL PROTEIN; BACTERIAL SECRETION SYSTEM;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; BIOENGINEERING; CONTROLLED STUDY; CYTOPLASM; DNA MODIFICATION; DRUG DELIVERY SYSTEM; EMBRYO; ESCHERICHIA COLI; HELA CELL LINE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN STABILITY; SHIGELLA FLEXNERI; TYPE III SECRETION SYSTEM; ANIMAL; BACTERIAL SECRETION SYSTEM; GENETIC ENGINEERING; GENETICS; MAMMAL; METABOLISM; PROCEDURES; PROTEIN TRANSPORT; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; VIRULENCE;

BACTERIA (MICROORGANISMS); ESCHERICHIA COLI; MAMMALIA; NEGIBACTERIA; SHIGELLA FLEXNERI;

ANIMALS; BACTERIAL PROTEINS; BACTERIAL SECRETION SYSTEMS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; ESCHERICHIA COLI; GENETIC ENGINEERING; HELA CELLS; HUMANS; MAMMALS; PLASMIDS; PROTEIN TRANSPORT; SHIGELLA FLEXNERI; VIRULENCE;

EID: 84929590051     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/acssynbio.5b00002     Document Type: Article

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