Regulated programmed lysis of recombinant Salmonella in host tissues to release protective antigens and confer biological containment

Proceedings of the National Academy of Sciences of the United States of America

Volumn 105, Issue 27, 2008, Pages 9361-9366

  Kong, Wei ^a,b   Wanda, Soo Young ^a,b   Zhang, Xin ^b   Bollen, Wendy ^b,d   Tinge, Steven A ^c   Roland, Kenneth L ^a   Curtiss III, Roy ^a,b  

^a ARIZONA STATE UNIVERSITY   (United States)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c Megan Health Inc   (United States)

^d Agnesian Healthcare   (United States)

Author keywords

Programmed cell lysis; rPspA; Rx1

Indexed keywords

ARABINOSE; BETA GALACTOSIDASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; APOPTOSIS; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BACTERIAL STRAIN; CONTROLLED STUDY; GENE CONTROL; GENE MUTATION; IMMUNE RESPONSE; LYSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; SALMONELLA TYPHIMURIUM; SALMONELLOSIS;

ANIMALS; ANTIGENS, BACTERIAL; ARABINOSE; BACTERIAL PROTEINS; BACTERIAL VACCINES; BACTERIOLYSIS; CODON; COLONY COUNT, MICROBIAL; CONTAINMENT OF BIOHAZARDS; FEMALE; HEAT-SHOCK PROTEINS; IMMUNIZATION; LYMPHOID TISSUE; MICE; MICE, INBRED BALB C; PLASMIDS; RECOMBINANT PROTEINS; SALMONELLA;

BACTERIA (MICROORGANISMS); MUS; NEGIBACTERIA; SALMONELLA; SALMONELLA ENTERICA SUBSP. ENTERICA SEROVAR TYPHIMURIUM; SALMONELLA TYPHIMURIUM; STREPTOCOCCUS PNEUMONIAE;

EID: 48249135779     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0803801105     Document Type: Article

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