Secretion of Ipa proteins by Shigella flexneri: Inducer molecules and kinetics of activation

Infection and Immunity

Volumn 65, Issue 10, 1997, Pages 4005-4010

  Bahrani, Farah K ^a,b   Sansonetti, Philippe J ^a   Parsot, Claude ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; CONGO RED;

ARTICLE; BACTERIAL VIRULENCE; COLON MUCOSA; GRAM NEGATIVE BACTERIUM; INTESTINE EPITHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SHIGELLA FLEXNERI; SHIGELLOSIS;

EID: 0030793819     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.65.10.4005-4010.1997     Document Type: Article

References (30)

1. Allaoui, A., P. J. Sansonetti, and C. Parsot. 1993. MxiD: an outer membrane protein necessary for the secretion of the Shigella flexneri Ipa invasins. Mol. Microbiol. 7:59-68.
2. Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, and K. Struhl (ed.). 1995. Current protocols in molecular biology, vol. 2, p. 10.8.1-10.8.17. John Wiley & Sons, Inc., New York, N.Y.
3. Bahrani, F. K., P. J. Sansonetti, and C. Parsot. 1997. Unpublished data.
4. Barzu, S., F. Nato, S. Rouyre, J.-C. Mazie, P. Sansonetti, and A. Phalipon. 1993. Characterization of B-cell epitopes of IpaB, an invasion-associated antigen of Shigella flexneri: identification of an immunodominant domain recognized during natural infection. Infect. Immun. 61:3825-3831.
5. Brinkworth, R. I., and D. P. Fairlie. 1992. Non-peptidic anti-AIDS agents: inhibition of HIV-1 proteinase by disulfonates. Biochem. Biophys. Res. Commun. 188:624-630.
6. Ladewig, P. 1945. Double-refringence of the amyloid Congo-Red-Complex in histological sections. Nature 156:81-82.
7. Ling, C. M., and L. R. Overby. 1972. Prevalence of hepatitis B virus antigen as revealed by direct radioimmune assay with 125 I-antibody. J. Immunol. 109:834-841.
8. Maurelli, A. T., B. Baudry, H. d'Hauteville, T. L. Hale, and P. J. Sansonetti. 1985. Cloning of plasmid DNA sequences involved in invasion of HeLa cells by Shigella flexneri. Infect. Immun. 49:164-171.
9. Maurelli, A. T., B. Blackmon, and R. Curtiss III. 1984. Loss of pigmentation in Shigella flexneri 2a is correlated with loss of virulence and virulence-associated plasmid. Infect. Immun. 43:397-401.
10. Ménard, R., M.-C. Prévost, P. Gounon, P. J. Sansonetti, and C. Dehio. 1996. The secreted Ipa complex of Shigella flexneri promotes entry into mammalian cells. Proc. Natl. Acad. Sci. USA 93:1254-1258.
11. Ménard, R., P. Sansonetti, and C. Parsot. 1994. The secretion of the Shigella flexneri invasins is activated by epithelial cells and controlled by IpaB and IpaD. EMBO J. 13:5293-5302.
12. Ménard, R., P. J. Sansonetti, and C. Parsot. 1993. Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells. J. Bacteriol. 175:5899-5906.
13. Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
14. Mounier, J., F. K. Bahrani, and P. J. Sansonetti. 1997. Secretion of Shigella flexneri Ipa invasins on contact with epithelial cells and subsequent entry of the bacterium into cells are growth stage dependent. Infect. Immun. 65:774-782.
15. Ojala, W. H., C. R. Ojala, and W. B. Gleason. 1995. The X-ray crystal structure of the sulfonated azo dye Congo red, a non-peptidic inhibitor of HIV-1 protease which also binds to reverse transcriptase and amyloid proteins. Antivir. Chem. Chemother. 6:25-33.
16. Parsot, C., R. Ménard, P. Gounon, and P. J. Sansonetti. 1995. Enhanced secretion through the Shigella flexneri Mxi-Spa translocon leads to assembly of extracellular proteins into macromolecular structures. Mol. Microbiol. 16:291-300.
17. Parsot, C., and P. J. Sansonetti. 1996. Invasion and pathogenesis of Shigella infections, p. 25-42. In V. L. Miller (ed.), Bacterial invasiveness. Springer-Verlag, New York, N.Y.
18. Payne, S. M., and R. A. Finkelstein. 1977. Detection and differentiation of iron-responsive avirulent mutants on Congo red agar. Infect. Immun. 18:94-98.
19. Pettersson, J., R. Nordfelth, E. Dubinina, T. Bergman, M. Gustafsson, K. E. Magnusson, and H. Wolf-Watz. 1996. Modulation of virulence factor expression by target cell contact. Science 273:1231-1233.
20. Phalipon, A., J. Arondel, F. Nato, S. Rouyre, J.-C. Mazie, and P. J. Sansonetti. 1992. Identification and characterization of B-cell epitopes of IpaC, an invasion-associated protein of Shigella flexneri. Infect. Immun. 60:1919-1926.
21. Pugsley, A. P. 1993. The complete general secretory pathway in gram-negative bacteria. Microbiol. Rev. 57:50-108.
22. Salmond, G. P. C., and P. J. Reeves. 1993. Membrane traffic wardens and protein secretion in Gram-negative bacteria. Trends Biochem. Sci. 18:7-11.
23. Sansonetti, P. J., D. J. Kopecko, and S. B. Formal. 1982. Involvement of a plasmid in the invasive ability of Shigella flexneri. Infect. Immun. 35:852-860.
24. Sasakawa, C., K. Kamata, T. Sakai, S. Makino, M. Yamada, N. Okada, and M. Yoshikawa. 1988. Virulence-associated genetic regions comprising 31 kilobases of the 230-kilobase plasmid in Shigella flexneri 2a. J. Bacteriol. 170:2480-2484.
25. Sasakawa, C., K. Kamata, T. Sakai, S. Y. Murayama, S. Makino, and M. Yoshikawa. 1986. Molecular alteration of the 140-megadalton plasmid associated with loss of virulence and Congo red binding activity in Shigella flexneri. Infect. Immun. 51:470-475.
26. Turnell, W. G., and J. T. Finch. 1992. Binding of the dye Congo red to the amyloid protein pig insulin reveals a novel homology amongst amyloid-forming peptide sequences. J. Mol. Biol. 227:1205-1223.
27. Van Gijsegem, F., S. Genin, and C. Boucher. 1993. Conservation of secretion pathways for pathogenicity determinants of plant and animal bacteria. Trends Microbiol. 1:175-180.
28. Van Gijsegem, F., C. Gough, C. Zischek, E. Niqueux, M. Arlat, S. Genin, P. Barberis, S. German, P. Castello, and C. Boucher. 1995. The hrp gene locus of Pseudomonas solanacearum, which controls the production of a type III secretion system, encodes eight proteins related to components of the bacterial flagellar biogenesis complex. Mol. Microbiol. 15:1095-1114.
29. Watari, M., T. Tobe, M. Yoshikawa, and C. Sasakawa. 1995. Contact of Shigella with host cells triggers release of Ipa invasins and is essential function of invasiveness. EMBO J. 14:2461-2470.
30. Zierler, M. K., and J. E. Galán. 1995. Contact with cultured epithelial cells stimulates secretion of Salmonella typhimurium invasion protein InvJ. Infect. Immun. 63:4024-4028.