Modular design of a synthetic payload delivery device

ACS Synthetic Biology

Volumn 2, Issue 8, 2013, Pages 418-424

  Huh, Jin H ^a,c   Kittleson, Josh T ^a,c   Arkin, Adam P ^a,b,c,d   Anderson, J Christopher ^a,b,c,d  

^a University of California at Berkeley   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

modular design; payload delivery; synthetic biology; system level engineering; tumor killing bacterium

Indexed keywords

PROTEIN;

ARTICLE; BIOLOGY; CANCER CELL; CELL FUNCTION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOPLASM; DRUG DELIVERY DEVICE; ESCHERICHIA COLI; GENE ACTIVITY; HELA CELL; IN VITRO STUDY; INVASION DEVICE; LYSIS; MACROMOLECULE; NONHUMAN; PAYLOAD DELIVERY DEVICE; PRIORITY JOURNAL; SELF LYSIS DEVICE; SYNTHETIC BIOLOGY; VACUOLE LYSIS DEVICE; VACUOLE SENSING DEVICE;

ANTI-BACTERIAL AGENTS; DRUG CARRIERS; DRUG DESIGN; ESCHERICHIA COLI; HELA CELLS; HUMANS; NEOPLASMS, EXPERIMENTAL; PROTEIN ENGINEERING; RECOMBINANT PROTEINS;

EID: 84882624208     PISSN: None     EISSN: 21615063     Source Type: Journal    
DOI: 10.1021/sb300107h     Document Type: Article

References (40)

1. Khalil, A. S. and Collins, J. J. (2010) Synthetic biology: applications come of age Nat. Rev. Genet. 11, 367-379
2. Endy, D. (2005) Foundations for engineering biology Nature 438, 449-453 (Pubitemid 41742010)
3. Purnick, P. E. and Weiss, R. (2009) The second wave of synthetic biology: from modules to systems Nat. Rev. Mol. Cell Biol. 10, 410-422
4. Prather, K. L. and Martin, C. H. (2008) De novo biosynthetic pathways: rational design of microbial chemical factories Curr. Opin. Biotechnol. 19, 468-474
5. Tabor, J. J., Salis, H. M., Simpson, Z. B., Chevalier, A. A., Levskaya, A., Marcotte, E. M., Voigt, C. A., and Ellington, A. D. (2009) A synthetic genetic edge detection program Cell 137, 1272-1281
6. Wang, B., Kitney, R. I., Joly, N., and Buck, M. (2011) Engineering modular and orthogonal genetic logic gates for robust digital-like synthetic biology Nat. Commun. 2, 508
7. Seow, Y. and Wood, M. J. (2009) Biological gene delivery vehicles: beyond viral vectors Mol. Ther. 17, 767-777
8. Courvalin, P., Goussard, S., and Grillot-Courvalin, C. (1995) Gene transfer from bacteria to mammalian cells C. R. Acad. Sci., Ser. III 318, 1207-1212
9. Larsen, M. D., Griesenbach, U., Goussard, S., Gruenert, D. C., Geddes, D. M., Scheule, R. K., Cheng, S. H., Courvalin, P., Grillot-Courvalin, C., and Alton, E. W. (2008) Bactofection of lung epithelial cells in vitro and in vivo using a genetically modified Escherichia coli Gene Ther. 15, 434-442 (Pubitemid 351331001)
10. Forbes, N. S. (2010) Engineering the perfect (bacterial) cancer therapy Nat. Rev. Cancer 10, 785-794
11. van Pijkeren, J. P., Morrissey, D., Monk, I. R., Cronin, M., Rajendran, S., O'Sullivan, G. C., Gahan, C. G., and Tangney, M. (2010) A novel Listeria monocytogenes-based DNA delivery system for cancer gene therapy Hum. Gene Ther. 21, 405-416
12. Yazawa, K., Fujimori, M., Nakamura, T., Sasaki, T., Amano, J., Kano, Y., and Taniguchi, S. (2001) Bifidobacterium longum as a delivery system for gene therapy of chemically induced rat mammary tumors Breast Cancer Res. Treat. 66, 165-170 (Pubitemid 32521423)
13. Sizemore, D. R., Branstrom, A. A., and Sadoff, J. C. (1995) Attenuated Shigella as a DNA delivery vehicle for DNA-mediated immunization Science 270, 299-302
14. Zhu, X., Cai, J., Huang, J., Jiang, X., and Ren, D. (2010) The treatment and prevention of mouse melanoma with an oral DNA vaccine carried by attenuated Salmonella typhimurium J. Immunother. 33, 453-460
15. Grillot-Courvalin, C., Goussard, S., Huetz, F., Ojcius, D. M., and Courvalin, P. (1998) Functional gene transfer from intracellular bacteria to mammalian cells Nat. Biotechnol. 16, 862-866 (Pubitemid 28405858)
16. Baban, C. K., Cronin, M., O'Hanlon, D., O'Sullivan, G. C., and Tangney, M. (2011) Bacteria as vectors for gene therapy of cancer Bioeng. Bugs 1, 385-394
17. Fajac, I., Grosse, S., Collombet, J. M., Thevenot, G., Goussard, S., Danel, C., and Grillot-Courvalin, C. (2004) Recombinant Escherichia coli as a gene delivery vector into airway epithelial cells J. Controlled Release 97, 371-381 (Pubitemid 38759493)
18. Castagliuolo, I., Beggiao, E., Brun, P., Barzon, L., Goussard, S., Manganelli, R., Grillot-Courvalin, C., and Palu, G. (2005) Engineered E. coli delivers therapeutic genes to the colonic mucosa Gene Ther. 12, 1070-1078 (Pubitemid 40946149)
19. Kalderon, D., Roberts, B. L., Richardson, W. D., and Smith, A. E. (1984) A short amino acid sequence able to specify nuclear location Cell 39, 499-509 (Pubitemid 15198589)
20. Anderson, J. C., Clarke, E. J., Arkin, A. P., and Voigt, C. A. (2006) Environmentally controlled invasion of cancer cells by engineered bacteria J. Mol. Biol. 355, 619-627 (Pubitemid 41817623)
21. Isberg, R. R. and Van Nhieu, G. T. (1995) The mechanism of phagocytic uptake promoted by invasin-integrin interaction Trends Cell Biol. 5, 120-124
22. Young, V. B., Falkow, S., and Schoolnik, G. K. (1992) The invasin protein of Yersinia enterocolitica: internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton J. Cell Biol. 116, 197-207
23. Ernst, R. K., Guina, T., and Miller, S. I. (1999) How intracellular bacteria survive: surface modifications that promote resistance to host innate immune responses J. Infect. Dis. 179 (Suppl 2) S326-330
24. Garcia Vescovi, E., Soncini, F. C., and Groisman, E. A. (1996) Mg2+ as an extracellular signal: environmental regulation of Salmonella virulence Cell 84, 165-174
25. White, R., Chiba, S., Pang, T., Dewey, J. S., Savva, C. G., Holzenburg, A., Pogliano, K., and Young, R. (2011) Holin triggering in real time Proc. Natl. Acad. Sci. U.S.A. 108, 798-803
26. Tran, T. A., Struck, D. K., and Young, R. (2005) Periplasmic domains define holin-antiholin interactions in t4 lysis inhibition J. Bacteriol. 187, 6631-6640 (Pubitemid 41356235)
27. Buchler, N. E. and Cross, F. R. (2009) Protein sequestration generates a flexible ultrasensitive response in a genetic network Mol. Syst. Biol. 5, 272
28. Zhang, N. and Young, R. (1999) Complementation and characterization of the nested Rz and Rz1 reading frames in the genome of bacteriophage lambda Mol. Gen. Genet. 262, 659-667 (Pubitemid 30018808)
29. O'Brien, D. K. and Melville, S. B. (2004) Effects of Clostridium perfringens alpha-toxin (PLC) and perfringolysin O (PFO) on cytotoxicity to macrophages, on escape from the phagosomes of macrophages, and on persistence of C. perfringens in host tissues Infect. Immun. 72, 5204-5215 (Pubitemid 39223406)
30. Smith, G. A., Marquis, H., Jones, S., Johnston, N. C., Portnoy, D. A., and Goldfine, H. (1995) The two distinct phospholipases C of Listeria monocytogenes have overlapping roles in escape from a vacuole and cell-to-cell spread Infect. Immun. 63, 4231-4237
31. Decatur, A. L. and Portnoy, D. A. (2000) A PEST-like sequence in listeriolysin O essential for Listeria monocytogenes pathogenicity Science 290, 992-995
32. Mogk, A., Schmidt, R., and Bukau, B. (2007) The N-end rule pathway for regulated proteolysis: prokaryotic and eukaryotic strategies Trends Cell Biol. 17, 165-172 (Pubitemid 46507804)
33. Luzio, J. P., Bright, N. A., and Pryor, P. R. (2007) The role of calcium and other ions in sorting and delivery in the late endocytic pathway Biochem. Soc. Trans. 35, 1088-1091 (Pubitemid 350206436)
34. Luirink, J., van der Sande, C., Tommassen, J., Veltkamp, E., De Graaf, F. K., and Oudega, B. (1986) Effects of divalent cations and of phospholipase A activity on excretion of cloacin DF13 and lysis of host cells J. Gen. Microbiol. 132, 825-834 (Pubitemid 16064067)
35. Tan, C., Marguet, P., and You, L. (2009) Emergent bistability by a growth-modulating positive feedback circuit Nat. Chem. Biol. 5, 842-848
36. Scott, M., Gunderson, C. W., Mateescu, E. M., Zhang, Z., and Hwa, T. (2010) Interdependence of cell growth and gene expression: origins and consequences Science 330, 1099-1102
37. Anderson, J. C., Dueber, J. E., Leguia, M., Wu, G. C., Goler, J. A., Arkin, A. P., and Keasling, J. D. (2010) BglBricks: A flexible standard for biological part assembly J. Biol. Eng. 4, 1
38. Leguia, M., Brophy, J., Densmore, D., and Anderson, J. C. (2011) Automated assembly of standard biological parts Methods Enzymol. 498, 363-397
39. Kato, A. and Groisman, E. A. (2004) Connecting two-component regulatory systems by a protein that protects a response regulator from dephosphorylation by its cognate sensor Genes Dev. 18, 2302-2313 (Pubitemid 39209578)
40. Kelly, J. R., Rubin, A. J., Davis, J. H., Ajo-Franklin, C. M., Cumbers, J., Czar, M. J., de Mora, K., Glieberman, A. L., Monie, D. D., and Endy, D. (2009) Measuring the activity of BioBrick promoters using an in vivo reference standard J. Biol. Eng. 3, 4