Human-Gyrovirus-Apoptin Triggers Mitochondrial Death Pathway-Nur77 is Required for Apoptosis Triggering

Neoplasia (United States)

Volumn 16, Issue 9, 2014, Pages 679-693

  Chaabane, Wiem ^a,b   Cieślar Pobuda, Artur ^a,c   El Gazzah, Mohamed ^b   Jain, Mayur V ^a   Rzeszowska Wolny, Joanna ^c   Rafat, Mehrdad ^a   Stetefeld, Joerg ^d   Ghavami, Saeid ^d   Łos, Marek J ^a,e  

^a LINKÖPING UNIVERSITY   (Sweden)

^b UNIVERSITY OF TUNIS   (Tunisia)

^c SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

^d UNIVERSITY OF MANITOBA   (Canada)

^e POMERANIAN MEDICAL UNIVERSITY   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84929572762     PISSN: 15228002     EISSN: 14765586     Source Type: Journal    
DOI: 10.1016/j.neo.2014.08.001     Document Type: Article

References (56)

1. Teodoro JG, Branton PE Regulation of apoptosis by viral gene products. J Virol 1997, 71:1739-1746.
2. Tait SW, Green DR Mitochondria and cell death: outer membrane permeabilization and beyond. Nat Rev Mol Cell Biol 2010, 11:621-632.
3. Kerr JF, Wyllie AH, Currie AR Apoptosis: a basic biological phenomenon with wide-ranging implications in tissue kinetics. Br J Cancer 1972, 26:239-257.
4. Youle RJ, Strasser A The BCL-2 protein family: opposing activities that mediate cell death. Nat Rev Mol Cell Biol 2008, 9:47-59.
5. Iglesias-Guimarais V, Gil-Guinon E, Sanchez-Osuna M, Casanelles E, Garcia-Belinchon M, Comella JX, Yuste VJ Chromatin collapse during caspase-dependent apoptotic cell death requires DFF40/CAD-mediated 3'-OH single-strand DNA breaks. J Biol Chem 2013, 288:9200-15. 10.1074/jbc.M112.411371.
6. Taylor RC, Cullen SP, Martin SJ Apoptosis: controlled demolition at the cellular level. Nat Rev Mol Cell Biol 2008, 9:231-241.
7. Los M, Wesselborg S, Schulze-Osthoff K The role of caspases in development, immunity, and apoptotic signal transduction: lessons from knockout mice. Immunity 1999, 10:629-639.
8. Greil R, Anether G, Johrer K, Tinhofer I Tracking death dealing by Fas and TRAIL in lymphatic neoplastic disorders: pathways, targets, and therapeutic tools. J Leukoc Biol 2003, 74:311-330.
9. Kuwana T, Newmeyer DD Bcl-2-family proteins and the role of mitochondria in apoptosis. Curr Opin Cell Biol 2003, 15:691-699.
10. Newmeyer DD, Ferguson-Miller S Mitochondria: releasing power for life and unleashing the machineries of death. Cell 2003, 112:481-490.
11. Chipuk JE, Moldoveanu T, Llambi F, Parsons MJ, Green DR The BCL-2 family reunion. Mol Cell 2010, 37:299-310.
12. Marchenko ND, Zaika A, Moll UM Death signal-induced localization of p53 protein to mitochondria. A potential role in apoptotic signaling. J Biol Chem 2000, 275:16202-16212.
13. Waterhouse NJ, Goldstein JC, von Ahsen O, Schuler M, Newmeyer DD, Green DR Cytochrome c maintains mitochondrial transmembrane potential and ATP generation after outer mitochondrial membrane permeabilization during the apoptotic process. J Cell Biol 2001, 153:319-328.
14. Sansome C, Zaika A, Marchenko ND, Moll UM Hypoxia death stimulus induces translocation of p53 protein to mitochondria. Detection by immunofluorescence on whole cells. FEBS Lett 2001, 488:110-115.
15. Moll UM, Marchenko N, Zhang XK p53 and Nur77/TR3-transcription factors that directly target mitochondria for cell death induction. Oncogene 2006, 25:4725-4743.
16. Wong RS Apoptosis in cancer: from pathogenesis to treatment. J Exp Clin Cancer Res 2011, 30:87. 10.1186/1756-9966-30-87.
17. Oro C, Jans DA The tumour specific pro-apoptotic factor apoptin (Vp3) from chicken anaemia virus. Curr Drug Targets 2004, 5:179-190.
18. Poon IKH, Oro C, Dias MM, Zhang JP, Jans DA A tumor cell-specific nuclear targeting signal within chicken anemia virus VP3/apoptin. J Virol 2005, 79:1339-1341.
19. Danen-Van Oorschot AA, Fischer DF, Grimbergen JM, Klein B, Zhuang S, Falkenburg JH, Backendorf C, Quax PH, der Eb AJ Van, Noteborn MH Apoptin induces apoptosis in human transformed and malignant cells but not in normal cells. Proc Natl Acad Sci U S A 1997, 94:5843-5847.
20. Jangamreddy JR, Panigrahi S, Lotfi K, Yadav M, Maddika S, Tripathi AK, Sanyal S, Los MJ Mapping of Apoptin-interaction with BCR-ABL1, and development of apoptin-based targeted therapy. Oncotarget 2014, [in press, 000966-R1].
21. Guelen L, Paterson H, Gaken J, Meyers M, Farzaneh F, Tavassoli M TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells. Oncogene 2004, 23:1153-1165.
22. Rohn JL, Zhang YH, Leliveld SR, Danen-van Oorschot AA, Henriquez NV, Abrahams JP, Noteborn MH Relevance of apoptin's integrity for its functional behavior. J Virol 2005, 79:1337-1338.
23. Sauvage V, Cheval J, Foulongne V, Gouilh MA, Pariente K, Manuguerra JC, Richardson J, Dereure O, Lecuit M, Burguiere A, et al. Identification of the first human gyrovirus, a virus related to chicken anemia virus. J Virol 2011, 85:7948-7950.
24. Rollano Peñaloza OM, Lewandowska M, Stetefeld J, Ossysek K, Madej M, Bereta J, Sobczak M, Shojaei S, Ghavami S, Łos MJ Apoptins: selective anticancer agents. Trends Mol Med 2014, 20. [In press]. 10.1016/j.molmed.2014.07.003.
25. Bullenkamp J, Cole D, Malik F, Alkhatabi H, Kulasekararaj A, Odell EW, Farzaneh F, Gaken J, Tavassoli M Human Gyrovirus Apoptin shows a similar subcellular distribution pattern and apoptosis induction as the chicken anaemia virus derived VP3/Apoptin. Cell Death Differ 2012, 3.
26. Almazan G, McKay R An oligodendrocyte precursor cell line from rat optic nerve. Brain Res 1992, 579:234-245.
27. Mascetti G, Carrara S, Vergani L Relationship between chromatin compactness and dye uptake for in situ chromatin stained with DAPI. Cytometry 2001, 44:113-119.
28. Hughes MA, Harper N, Butterworth M, Cain K, Cohen GM, MacFarlane M Reconstitution of the Death-inducing Signaling Comp ex Reveals a Substrate Switch that Determines CD95-Mediated Death or Survival. Mol Cell 2009, 35:265-279.
29. Xerri L, Devilard E, Bouabdallah R, Stoppa AM, Hassoun J, Birg F FADD expression and caspase activation in B-cell lymphomas resistant to Fas-mediated apoptosis. Br J Haematol 1999, 106:652-661.
30. Aggarwal S, Gupta S Increased activity of caspase 3 and caspase 8 in anti-Fas-induced apoptosis in lymphocytes from ageing humans. Clin Exp Immunol 1999, 117:285-290.
31. Kim JW, Choi EJ, Joe CO Activation of death-inducing signaling complex (DISC) by pro-apoptotic C-terminal fragment of RIP. Oncogene 2000, 19:4491-4499.
32. Elmore S Apoptosis: A review of programmed cell death. Toxicol Pathol 2007, 35:495-516.
33. Lugli E, Troiano L, Ferraresi R, Roat E, Prada N, Nasi M, Pinti M, Cooper EL, Cossarizza A Characterization of cells with different mitochondrial membrane potential during apoptosis. Cytometry A 2005, 68:28-35.
34. Vaseva AV, Marchenko ND, Ji K, Tsirka SE, Holzmann S, Moll UM p53 opens the mitochondrial permeability transition pore to trigger necrosis. Cell 2012, 149:1536-1548.
35. Arnoult D, Parone P, Martinou JC, Antonsson B, Estaquier J, Ameisen JC Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli. J Cell Biol 2002, 159:923-929.
36. Martinou JC, Green DR Breaking the mitochondrial barrier. Nat Rev Mol Cell Biol 2001, 2:63-67.
37. Riedl SJ, Salvesen GS The apoptosome: signalling platform of cell death. Nat Rev Mol Cell Biol 2007, 8:405-413.
38. Erster S, Moll UM Stress-induced p53 runs a direct mitochondrial death program: its role in physiologic and pathophysiologic stress responses in vivo. Cell Cycle 2004, 3:1492-1495.
39. Rajpal A, Cho YA, Yelent B, Koza-Taylor PH, Li D, Chen E, Whang M, Kang C, Turi TG, Winoto A Transcriptional activation of known and novel apoptotic pathways by Nur77 orphan steroid receptor. EMBO J 2003, 22:6526-6536.
40. Noteborn MH Proteins selectively killing tumor cells. Eur J Pharmacol 2009, 625:165-173.
41. Zhuang SM, Landegent JE, Verschueren CA, Falkenburg JH, van Ormondt H, van der Eb AJ, Noteborn MH Apoptin, a protein encoded by chicken anemia virus, induces cell death in various human hematologic malignant cells in vitro. Leukemia 1995, 9(Suppl. 1):S118-S120.
42. Dhein J, Walczak H, Baumler C, Debatin KM, Krammer PH Autocrine T-cell suicide mediated by APO-1/(Fas/CD95). Nature 1995, 373:438-441.
43. Dhein J, Walczak H, Westendorp MO, Baumler C, Stricker K, Frank R, Debatin KM, Krammer PH Molecular mechanisms of APO-1/Fas(CD95)-mediated apoptosis in tolerance and AIDS. Behring Inst Mitt 1995, 13-20.
44. Fulda S, Los M, Friesen C, Debatin KM Chemosensitivity of solid tumor cells in vitro is related to activation of the CD95 system. Int J Cancer 1998, 76:105-114.
45. Brunner T, Mogil RJ, Laface D, Yoo NJ, Mahboubi A, Echeverri F, Martin SJ, Force WR, Lynch DH, Ware CF, et al. Cell-autonomous Fas (Cd95) Fas-ligand interaction mediates activation-induced apoptosis in T-cell hybridomas. Nature 1995, 373:441-444.
46. Holler N, Zaru R, Micheau O, Thome M, Attinger A, Valitutti S, Bodmer JL, Schneider P, Seed B, Tschopp J Fas triggers an alternative, caspase-8-independent cell death pathway using the kinase RIP as effector molecule. Nat Immunol 2000, 1:489-495.
47. Martinou JC, Desagher S, Antonsson B Cytochrome c release from mitochondria: all or nothing. Nat Cell Biol 2000, 2:E41-E43.
48. Creagh EM, Martin SJ Cell stress-associated caspase activation: intrinsically complex?. Sci STKE 2003, 10.1126/stke.2003.175.pe11.
49. Renz A, Berdel WE, Kreuter M, Belka C, Schulze-Osthoff K, Los M Rapid extracellular release of cytochrome c is specific for apoptosis and marks cell death in vivo. Blood 2001, 98:1542-1548.
50. Schulze-Osthoff K, Ferrari D, Los M, Wesselborg S, Peter ME Apoptosis signaling by death receptors. Eur J Biochem 1998, 254:439-459.
51. Bratton SB, Walker G, Srinivasula SM, Sun XM, Butterworth M, Alnemri ES, Cohen GM Recruitment, activation and retention of caspases-9 and -3 by Apaf-1 apoptosome and associated XIAP complexes. EMBO J 2001, 20:998-1009.
52. Bratton SB, Salvesen GS Regulation of the Apaf-1-caspase-9 apoptosome. J Cell Sci 2010, 123:3209-3214.
53. Marsden VS, Strasser A Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. Annu Rev Immunol 2003, 21:71-105.
54. Lindsten T, Ross AJ, King A, Zong WX, Rathmell JC, Shiels HA, Ulrich E, Waymire KG, Mahar P, Frauwirth K, et al. The combined functions of proapoptotic Bcl-2 family members Bak and Bax are essential for normal development of multiple tissues. Mol Cell 2000, 6:1389-1399.
55. Rivlin N, Brosh R, Oren M, Rotter V Mutations in the p53 tumor suppressor gene: important milestones at the various steps of tumorigenesis. Genes Cancer 2011, 2:466-474.
56. Wattel E, Preudhomme C, Hecquet B, Vanrumbeke M, Quesnel B, Dervite I, Morel P, Fenaux P p53 mutations are associated with resistance to chemotherapy and short survival in hematologic malignancies. Blood 1994, 84:3148-3157.