Protective effect of proanthocyanidins on anoxia-reoxygenation injury of myocardial cells mediated by the PI3K/Akt/GSK-3β pathway and mitochondrial ATP-sensitive potassium channel

Molecular Medicine Reports

Volumn 10, Issue 4, 2014, Pages 2051-2058

  Hu, Yanyan ^a   Li, L I ^b   Yin, Wenbin ^a   Shen, Lin ^a   You, Beian ^a   Gao, Haiqing ^a  

^a SHANDONG UNIVERSITY   (China)

^b SHANDONG UNIVERSITY   (China)

Author keywords

Anoxia reoxygenation; Apoptosis; Mitochondrial ATP sensitive potassium channel; PI3K Akt GSK 3 signaling pathway

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; ADENOSINE TRIPHOSPHATE SENSITIVE POTASSIUM CHANNEL; CASPASE 3; DNA NUCLEOTIDYLEXOTRANSFERASE; GLYCOGEN SYNTHASE KINASE 3BETA; PHOSPHATIDYLINOSITOL 3 KINASE; PROANTHOCYANIDIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; 2-(4-MORPHOLINYL)-8-PHENYL-4H-1-BENZOPYRAN-4-ONE; CHROMONE DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MITOCHONDRIAL K(ATP) CHANNEL; MORPHOLINE DERIVATIVE; OXYGEN; POTASSIUM CHANNEL; PROTECTIVE AGENT;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL PROTECTION; CELL SURVIVAL; CONTROLLED STUDY; FLOW CYTOMETRY; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE ISCHEMIA; HEART PROTECTION; MTT ASSAY; NEWBORN; NICK END LABELING; NONHUMAN; PROTEIN EXPRESSION; RAT; REDUCTION; REOXYGENATION; SIGNAL TRANSDUCTION; SURVIVAL RATE; WESTERN BLOTTING; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; CELL CULTURE; CELL HYPOXIA; CYTOLOGY; DRUG EFFECTS; METABOLISM; PHOSPHORYLATION; SPRAGUE DAWLEY RAT;

ANIMALS; APOPTOSIS; CELL HYPOXIA; CELL SURVIVAL; CELLS, CULTURED; CHROMONES; GLYCOGEN SYNTHASE KINASE 3; MODELS, BIOLOGICAL; MORPHOLINES; MYOCYTES, CARDIAC; OXYGEN; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; POTASSIUM CHANNELS; PROANTHOCYANIDINS; PROTECTIVE AGENTS; PROTO-ONCOGENE PROTEINS C-AKT; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 84929518068     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr.2014.2459     Document Type: Article

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