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Volumn 20, Issue 3, 2014, Pages 361-375

Protective effects elicited by levosimendan against liver ischemia/reperfusion injury in anesthetized rats

Author keywords

[No Author keywords available]

Indexed keywords

5 HYDROXYDECANOIC ACID; ADENOSINE TRIPHOSPHATE; ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CASPASE 3; CASPASE 9; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE; LEVOSIMENDAN; MALONALDEHYDE; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROTEIN BAX; PROTEIN BCL X; PROTEIN KINASE B; THIOBARBITURIC ACID REACTIVE SUBSTANCE;

EID: 84896726810     PISSN: 15276465     EISSN: 15276473     Source Type: Journal    
DOI: 10.1002/lt.23799     Document Type: Article
Times cited : (47)

References (52)
  • 1
    • 0032881237 scopus 로고    scopus 로고
    • Therapeutic approaches for ischemia/reperfusion injury in the liver
    • Fan C, Zwacka RM, Engelhardt JF,. Therapeutic approaches for ischemia/reperfusion injury in the liver. J Mol Med (Berl) 1999; 77: 577-592.
    • (1999) J Mol Med (Berl) , vol.77 , pp. 577-592
    • Fan, C.1    Zwacka, R.M.2    Engelhardt, J.F.3
  • 3
    • 0031011548 scopus 로고    scopus 로고
    • Reperfusion injury after liver preservation for transplantation
    • Lemasters JJ, Thurman RG,. Reperfusion injury after liver preservation for transplantation. Annu Rev Pharmacol Toxicol 1997; 37: 327-338.
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 327-338
    • Lemasters, J.J.1    Thurman, R.G.2
  • 6
    • 79961032414 scopus 로고    scopus 로고
    • Liver ischemia and reperfusion injury: New insights into mechanisms of innate-adaptive immune-mediated tissue inflammation
    • Zhai Y, Busuttil RW, Kupiec-Weglinski JW,. Liver ischemia and reperfusion injury: new insights into mechanisms of innate-adaptive immune-mediated tissue inflammation. Am J Transplant 2011; 11: 1563-1569.
    • (2011) Am J Transplant , vol.11 , pp. 1563-1569
    • Zhai, Y.1    Busuttil, R.W.2    Kupiec-Weglinski, J.W.3
  • 7
    • 70349838737 scopus 로고    scopus 로고
    • Cytoprotective effects of human interleukin-10 gene transfer against necrosis and apoptosis induced by hepatic cold ischemia/reperfusion injury
    • Li JQ, Qi HZ, He ZJ, Hu W, Si ZZ, Li YN, Li DB,. Cytoprotective effects of human interleukin-10 gene transfer against necrosis and apoptosis induced by hepatic cold ischemia/reperfusion injury. J Surg Res 2009; 157: e71-e78.
    • (2009) J Surg Res , vol.157
    • Li, J.Q.1    Qi, H.Z.2    He, Z.J.3    Hu, W.4    Si, Z.Z.5    Li, Y.N.6    Li, D.B.7
  • 8
    • 0031778208 scopus 로고    scopus 로고
    • Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation
    • Gao W, Bentley RC, Madden JF, Clavien PA,. Apoptosis of sinusoidal endothelial cells is a critical mechanism of preservation injury in rat liver transplantation. Hepatology 1998; 27: 1652-1660.
    • (1998) Hepatology , vol.27 , pp. 1652-1660
    • Gao, W.1    Bentley, R.C.2    Madden, J.F.3    Clavien, P.A.4
  • 9
    • 3843142885 scopus 로고    scopus 로고
    • Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1
    • Wang Y, Schattenberg JM, Rigoli RM, Storz P, Czaja MJ,. Hepatocyte resistance to oxidative stress is dependent on protein kinase C-mediated down-regulation of c-Jun/AP-1. J Biol Chem 2004; 279: 31089-31097.
    • (2004) J Biol Chem , vol.279 , pp. 31089-31097
    • Wang, Y.1    Schattenberg, J.M.2    Rigoli, R.M.3    Storz, P.4    Czaja, M.J.5
  • 11
    • 80051673122 scopus 로고    scopus 로고
    • Melatonin prevents hepatic injury-induced decrease in Akt downstream targets phosphorylations
    • Koh PO,. Melatonin prevents hepatic injury-induced decrease in Akt downstream targets phosphorylations. J Pineal Res 2011; 51: 214-219.
    • (2011) J Pineal Res , vol.51 , pp. 214-219
    • Koh, P.O.1
  • 12
    • 80054985592 scopus 로고    scopus 로고
    • Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway
    • Guo JY, Yang T, Sun XG, Zhou NY, Li FS, Long D, et al. Ischemic postconditioning attenuates liver warm ischemia-reperfusion injury through Akt-eNOS-NO-HIF pathway. J Biomed Sci 2011; 18: 79.
    • (2011) J Biomed Sci , vol.18 , pp. 79
    • Guo, J.Y.1    Yang, T.2    Sun, X.G.3    Zhou, N.Y.4    Li, F.S.5    Long, D.6
  • 13
    • 0028172183 scopus 로고
    • 2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study
    • 2+ sensitizer, levosimendan, to recombinant human cardiac troponin C. A molecular modelling, fluorescence probe, and proton nuclear magnetic resonance study. J Biol Chem 1994; 269: 28584-28590.
    • (1994) J Biol Chem , vol.269 , pp. 28584-28590
    • Pollesello, P.1    Ovaska, M.2    Kaivola, J.3    Tilgmann, C.4    Lundström, K.5    Kalkkinen, N.6
  • 15
    • 0013302144 scopus 로고    scopus 로고
    • Calcium sensitivity enhancers
    • Haikala H, Pollesello P,. Calcium sensitivity enhancers. IDrugs 2000; 3: 1199-1205.
    • (2000) IDrugs , vol.3 , pp. 1199-1205
    • Haikala, H.1    Pollesello, P.2
  • 16
    • 0035088001 scopus 로고    scopus 로고
    • Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels
    • Kaheinen P, Pollesello P, Levijoki J, Haikala H,. Levosimendan increases diastolic coronary flow in isolated guinea-pig heart by opening ATP-sensitive potassium channels. J Cardiovasc Pharmacol 2001; 37: 367-374.
    • (2001) J Cardiovasc Pharmacol , vol.37 , pp. 367-374
    • Kaheinen, P.1    Pollesello, P.2    Levijoki, J.3    Haikala, H.4
  • 17
    • 24344455110 scopus 로고    scopus 로고
    • Hemodynamic effect of intracoronary administration of levosimendan in the anesthetized pig
    • Grossini E, Caimmi PP, Molinari C, Teodori G, Vacca G,. Hemodynamic effect of intracoronary administration of levosimendan in the anesthetized pig. J Cardiovasc Pharmacol 2005; 46: 333-342.
    • (2005) J Cardiovasc Pharmacol , vol.46 , pp. 333-342
    • Grossini, E.1    Caimmi, P.P.2    Molinari, C.3    Teodori, G.4    Vacca, G.5
  • 18
    • 67650242870 scopus 로고    scopus 로고
    • Levosimendan induces NO production through p38 MAPK, ERK and Akt in porcine coronary endothelial cells: Role for mitochondrial K(ATP) channel
    • Grossini E, Molinari C, Caimmi PP, Uberti F, Vacca G,. Levosimendan induces NO production through p38 MAPK, ERK and Akt in porcine coronary endothelial cells: role for mitochondrial K(ATP) channel. Br J Pharm 2009; 156: 250-261.
    • (2009) Br J Pharm , vol.156 , pp. 250-261
    • Grossini, E.1    Molinari, C.2    Caimmi, P.P.3    Uberti, F.4    Vacca, G.5
  • 20
    • 36049020354 scopus 로고    scopus 로고
    • Effects of levosimendan on circulating markers of oxidative and nitrosative stress in patients with advanced heart failure
    • Parissis JT, Andreadou I, Markantonis SL, Bistola V, Louka A, Pyriochou A, et al. Effects of levosimendan on circulating markers of oxidative and nitrosative stress in patients with advanced heart failure. Atherosclerosis 2007; 195: e210-e215.
    • (2007) Atherosclerosis , vol.195
    • Parissis, J.T.1    Andreadou, I.2    Markantonis, S.L.3    Bistola, V.4    Louka, A.5    Pyriochou, A.6
  • 21
    • 34047270901 scopus 로고    scopus 로고
    • The effects of levosimendan in cardiac surgery patients with poor left ventricular function
    • De Hert SG, Lorsomradee S, Cromheecke S, Van der Linden PJ,. The effects of levosimendan in cardiac surgery patients with poor left ventricular function. Anesth Analg 2007; 104: 766-773.
    • (2007) Anesth Analg , vol.104 , pp. 766-773
    • De Hert, S.G.1    Lorsomradee, S.2    Cromheecke, S.3    Van Der Linden, P.J.4
  • 22
    • 79952533901 scopus 로고    scopus 로고
    • Intracoronary levosimendan prevents myocardial ischemic damages and activates survival signaling through ATP-sensitive potassium channel and nitric oxide
    • Caimmi PP, Molinari C, Uberti F, Micalizzi E, Valente G, Mary DA, et al. Intracoronary levosimendan prevents myocardial ischemic damages and activates survival signaling through ATP-sensitive potassium channel and nitric oxide. Eur J Cardiothorac Surg 2011; 39: e59-e67.
    • (2011) Eur J Cardiothorac Surg , vol.39
    • Caimmi, P.P.1    Molinari, C.2    Uberti, F.3    Micalizzi, E.4    Valente, G.5    Mary, D.A.6
  • 23
    • 79951555024 scopus 로고    scopus 로고
    • Levosimendan modulates programmed forms of cell death through K(ATP) channels and nitric oxide
    • Uberti F, Caimmi PP, Molinari C, Mary D, Vacca G, Grossini E,. Levosimendan modulates programmed forms of cell death through K(ATP) channels and nitric oxide. J Cardiovasc Pharmacol 2011; 57: 246-258.
    • (2011) J Cardiovasc Pharmacol , vol.57 , pp. 246-258
    • Uberti, F.1    Caimmi, P.P.2    Molinari, C.3    Mary, D.4    Vacca, G.5    Grossini, E.6
  • 24
    • 77951294283 scopus 로고    scopus 로고
    • Modulation of programmed forms of cell death by intracoronary levosimendan during regional myocardial ischemia in anesthetized pigs
    • Grossini E, Caimmi PP, Platini F, Molinari C, Uberti F, Cattaneo M, et al. Modulation of programmed forms of cell death by intracoronary levosimendan during regional myocardial ischemia in anesthetized pigs. Cardiovasc Drugs Ther 2010; 24: 5-15.
    • (2010) Cardiovasc Drugs Ther , vol.24 , pp. 5-15
    • Grossini, E.1    Caimmi, P.P.2    Platini, F.3    Molinari, C.4    Uberti, F.5    Cattaneo, M.6
  • 26
    • 84866324118 scopus 로고    scopus 로고
    • Protective effects of chlorogenic acid against ischemia/reperfusion injury in rat liver: Molecular evidence of its antioxidant and anti-inflammatory properties
    • Yun N, Kang JW, Lee SM,. Protective effects of chlorogenic acid against ischemia/reperfusion injury in rat liver: molecular evidence of its antioxidant and anti-inflammatory properties. J Nutr Biochem 2012; 23: 1249-1255.
    • (2012) J Nutr Biochem , vol.23 , pp. 1249-1255
    • Yun, N.1    Kang, J.W.2    Lee, S.M.3
  • 27
    • 68549125211 scopus 로고    scopus 로고
    • Protective effect of l -arginine against necrosis and apoptosis induced by experimental ischemic and reperfusion in rat liver
    • Chattopadhyay P, Shukla G, Wahi AK,. Protective effect of l -arginine against necrosis and apoptosis induced by experimental ischemic and reperfusion in rat liver. Saudi J Gastroenterol 2009; 15: 156-162.
    • (2009) Saudi J Gastroenterol , vol.15 , pp. 156-162
    • Chattopadhyay, P.1    Shukla, G.2    Wahi, A.K.3
  • 29
    • 82455175742 scopus 로고    scopus 로고
    • Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats
    • Lee LY, Kaizu T, Toyokawa H, Zhang M, Ross M, Stolz DB, et al. Carbon monoxide induces hypothermia tolerance in Kupffer cells and attenuates liver ischemia/reperfusion injury in rats. Liver Transpl 2011; 17: 1457-1466.
    • (2011) Liver Transpl , vol.17 , pp. 1457-1466
    • Lee, L.Y.1    Kaizu, T.2    Toyokawa, H.3    Zhang, M.4    Ross, M.5    Stolz, D.B.6
  • 30
    • 34547623793 scopus 로고    scopus 로고
    • Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model
    • Duenschede F, Erbes K, Riegler N, Ewald P, Kircher A, Westermann S, et al. Protective effects of ischemic preconditioning and application of lipoic acid prior to 90 min of hepatic ischemia in a rat model. World J Gastroenterol 2007; 13: 3692-3698.
    • (2007) World J Gastroenterol , vol.13 , pp. 3692-3698
    • Duenschede, F.1    Erbes, K.2    Riegler, N.3    Ewald, P.4    Kircher, A.5    Westermann, S.6
  • 31
    • 8644267479 scopus 로고    scopus 로고
    • Caspase 3 inhibition improves survival and reduces early graft injury after ischemia and reperfusion in rat liver transplantation
    • Mueller TH, Kienle K, Beham A, Geissler EK, Jauch KW, Rentsch M,. Caspase 3 inhibition improves survival and reduces early graft injury after ischemia and reperfusion in rat liver transplantation. Transplantation 2004; 78: 1267-1273.
    • (2004) Transplantation , vol.78 , pp. 1267-1273
    • Mueller, T.H.1    Kienle, K.2    Beham, A.3    Geissler, E.K.4    Jauch, K.W.5    Rentsch, M.6
  • 33
    • 0032717036 scopus 로고    scopus 로고
    • Protective effect of liver ischemic preconditioning on liver and lung injury induced by hepatic ischemia-reperfusion in the rat
    • Peralta C, Prats N, Xaus C, Gelpí E, Rosellõ-Catafau J,. Protective effect of liver ischemic preconditioning on liver and lung injury induced by hepatic ischemia-reperfusion in the rat. Hepatology 1999; 30: 1481-1489.
    • (1999) Hepatology , vol.30 , pp. 1481-1489
    • Peralta, C.1    Prats, N.2    Xaus, C.3    Gelpí, E.4    Rosellõ-Catafau, J.5
  • 34
    • 84875400979 scopus 로고    scopus 로고
    • Molecular mechanisms of liver ischemia reperfusion injury: Insights from transgenic knockout models
    • Datta G, Fuller BJ, Davidson BR,. Molecular mechanisms of liver ischemia reperfusion injury: insights from transgenic knockout models. World J Gastroenterol 2013; 19: 1683-1698.
    • (2013) World J Gastroenterol , vol.19 , pp. 1683-1698
    • Datta, G.1    Fuller, B.J.2    Davidson, B.R.3
  • 35
    • 0033841726 scopus 로고    scopus 로고
    • The role of mitochondrial K(ATP) channels in cardioprotection
    • Sato T, Marbán E,. The role of mitochondrial K(ATP) channels in cardioprotection. Basic Res Cardiol 2000; 95: 285-289.
    • (2000) Basic Res Cardiol , vol.95 , pp. 285-289
    • Sato, T.1    Marbán, E.2
  • 36
    • 0345363193 scopus 로고    scopus 로고
    • The effect of nitric oxide on ischemia-reperfusion injury in rat liver
    • Köken T, Inal M,. The effect of nitric oxide on ischemia-reperfusion injury in rat liver. Clin Chim Acta 1999; 288: 55-62.
    • (1999) Clin Chim Acta , vol.288 , pp. 55-62
    • Köken, T.1    Inal, M.2
  • 37
    • 79958757918 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion
    • Ben Mosbah I, Alfany-Fernández I, Martel C, Zaouali MA, Bintanel-Morcillo M, Rimola A, et al. Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia-reperfusion. Cell Death Dis 2010; 1: e52.
    • (2010) Cell Death Dis , vol.1
    • Ben Mosbah, I.1    Alfany-Fernández, I.2    Martel, C.3    Zaouali, M.A.4    Bintanel-Morcillo, M.5    Rimola, A.6
  • 38
    • 0030581151 scopus 로고    scopus 로고
    • Induction of apoptotic program in cell-free extracts: Requirement for dATP and cytochrome C
    • Liu X, Kim CN, Yang J, Jemmerson R, Wang X,. Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome C. Cell 1996; 86: 147-157.
    • (1996) Cell , vol.86 , pp. 147-157
    • Liu, X.1    Kim, C.N.2    Yang, J.3    Jemmerson, R.4    Wang, X.5
  • 39
    • 0031888955 scopus 로고    scopus 로고
    • A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD
    • Enari M, Sakahira H, Yokoyama H, Okawa K, Iwamatsu A, Nagata S,. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. Nature 1998; 391: 43-50.
    • (1998) Nature , vol.391 , pp. 43-50
    • Enari, M.1    Sakahira, H.2    Yokoyama, H.3    Okawa, K.4    Iwamatsu, A.5    Nagata, S.6
  • 40
    • 0033005752 scopus 로고    scopus 로고
    • A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis
    • Cursio R, Gugenheim J, Ricci JE, Crenesse D, Rostagno P, Maulon L, et al. A caspase inhibitor fully protects rats against lethal normothermic liver ischemia by inhibition of liver apoptosis. FASEB J 1999; 13: 253-261.
    • (1999) FASEB J , vol.13 , pp. 253-261
    • Cursio, R.1    Gugenheim, J.2    Ricci, J.E.3    Crenesse, D.4    Rostagno, P.5    Maulon, L.6
  • 41
    • 84883554868 scopus 로고    scopus 로고
    • Dietary omega-3 polyunsaturated fatty acids attenuate hepatic ischemia/reperfusion injury in rats by modulating toll-like receptor recruitment into lipid rafts
    • Kim K, Jung N, Lee K, Choi J, Kim S, Jun J, et al. Dietary omega-3 polyunsaturated fatty acids attenuate hepatic ischemia/reperfusion injury in rats by modulating toll-like receptor recruitment into lipid rafts. Clin Nutr 2013; 32: 855-862.
    • (2013) Clin Nutr , vol.32 , pp. 855-862
    • Kim, K.1    Jung, N.2    Lee, K.3    Choi, J.4    Kim, S.5    Jun, J.6
  • 42
    • 38149041790 scopus 로고    scopus 로고
    • Protective effect of 17β-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway
    • Satake A, Takaoka M, Nishikawa M, Yuba M, Shibata Y, Okumura K, et al. Protective effect of 17β-estradiol on ischemic acute renal failure through the PI3K/Akt/eNOS pathway. Kidney Int 2008; 73: 308-317.
    • (2008) Kidney Int , vol.73 , pp. 308-317
    • Satake, A.1    Takaoka, M.2    Nishikawa, M.3    Yuba, M.4    Shibata, Y.5    Okumura, K.6
  • 43
    • 78650612002 scopus 로고    scopus 로고
    • Neuregulin-1 preconditioning protects the heart against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism
    • Fang SJ, Wu XS, Han ZH, Zhang XX, Wang CM, Li XY, et al. Neuregulin-1 preconditioning protects the heart against ischemia/reperfusion injury through a PI3K/Akt-dependent mechanism. Chin Med J (Engl) 2010; 123: 3597-3604.
    • (2010) Chin Med J (Engl) , vol.123 , pp. 3597-3604
    • Fang, S.J.1    Wu, X.S.2    Han, Z.H.3    Zhang, X.X.4    Wang, C.M.5    Li, X.Y.6
  • 44
    • 0021086270 scopus 로고
    • ATP-regulated K+ channels in cardiac muscle
    • Noma A,. ATP-regulated K+ channels in cardiac muscle. Nature 1983; 305: 147-148.
    • (1983) Nature , vol.305 , pp. 147-148
    • Noma, A.1
  • 45
    • 0035823614 scopus 로고    scopus 로고
    • Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain
    • Bajgar R, Seetharaman S, Kowaltowski AJ, Garlid KD, Paucek P,. Identification and properties of a novel intracellular (mitochondrial) ATP-sensitive potassium channel in brain. J Biol Chem 2001; 276: 33369-33374.
    • (2001) J Biol Chem , vol.276 , pp. 33369-33374
    • Bajgar, R.1    Seetharaman, S.2    Kowaltowski, A.J.3    Garlid, K.D.4    Paucek, P.5
  • 47
    • 0025913049 scopus 로고
    • ATP-sensitive K+ channel in the mitochondrial inner membrane
    • Inoue I, Nagase H, Kishi K, Higuti T,. ATP-sensitive K+ channel in the mitochondrial inner membrane. Nature 1991; 352: 244-247.
    • (1991) Nature , vol.352 , pp. 244-247
    • Inoue, I.1    Nagase, H.2    Kishi, K.3    Higuti, T.4
  • 48
    • 0037432161 scopus 로고    scopus 로고
    • Mitochondrial ATP-sensitive K+ channel opening decreases reactive oxygen species generation
    • Ferranti R, da Silva MM, Kowaltowski AJ,. Mitochondrial ATP-sensitive K+ channel opening decreases reactive oxygen species generation. FEBS Lett 2003; 536: 51-55.
    • (2003) FEBS Lett , vol.536 , pp. 51-55
    • Ferranti, R.1    Da Silva, M.M.2    Kowaltowski, A.J.3
  • 49
    • 84866164295 scopus 로고    scopus 로고
    • Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver transplantation in rats
    • Zeng Z, Huang HF, He F, Wu LX, Lin J, Chen MQ,. Diazoxide attenuates ischemia/reperfusion injury via upregulation of heme oxygenase-1 after liver transplantation in rats. World J Gastroenterol 2012; 18: 1765-1772.
    • (2012) World J Gastroenterol , vol.18 , pp. 1765-1772
    • Zeng, Z.1    Huang, H.F.2    He, F.3    Wu, L.X.4    Lin, J.5    Chen, M.Q.6
  • 50
    • 84891793214 scopus 로고    scopus 로고
    • Levosimendan: A cardiovascular drug to prevent liver ischemia-reperfusion injury?
    • Onody P, Stangl R, Fulop A, Rosero O, Garbaisz D, Turoczi Z, et al. Levosimendan: a cardiovascular drug to prevent liver ischemia-reperfusion injury? PLoS One 2013; 8: e73758.
    • (2013) PLoS One , vol.8
    • Onody, P.1    Stangl, R.2    Fulop, A.3    Rosero, O.4    Garbaisz, D.5    Turoczi, Z.6
  • 51
    • 0026751233 scopus 로고
    • Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies
    • Clavien PA, Harvey PR, Strasberg SM,. Preservation and reperfusion injuries in liver allografts. An overview and synthesis of current studies. Transplantation 1992; 53: 957-978.
    • (1992) Transplantation , vol.53 , pp. 957-978
    • Clavien, P.A.1    Harvey, P.R.2    Strasberg, S.M.3
  • 52
    • 33746868875 scopus 로고    scopus 로고
    • Gene therapy in liver ischemia and reperfusion injury
    • Ke B, Lipshutz GS, Kupiec-Weglinski JW,. Gene therapy in liver ischemia and reperfusion injury. Curr Pharm Des 2006; 12: 2969-2975.
    • (2006) Curr Pharm des , vol.12 , pp. 2969-2975
    • Ke, B.1    Lipshutz, G.S.2    Kupiec-Weglinski, J.W.3


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