Trauma in silico: Individual-specific mathematical models and virtual clinical populations

Science Translational Medicine

Volumn 7, Issue 285, 2015, Pages

  Brown, David ^a   Namas, Rami A ^b   Almahmoud, Khalid ^b   Zaaqoq, Akram ^b   Sarkar, Joydeep ^b   Barclay, Derek A ^a   Yin, Jinling ^b   Ghuma, Ali ^b   Abboud, Andrew ^b   Constantine, Gregory ^c   Nieman, Gary ^d   Zamora, Ruben ^b,e   Chang, Steven C ^a   Billiar, Timothy R ^b   Vodovotz, Yoram ^b,e  

^a IMMUNETRICS INC   (United States)

^b UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d State University of New York Upstate Medical University: College of Medicine   (United States)

^e MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 10; INTERLEUKIN 12P40; INTERLEUKIN 1BETA; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLUNT TRAUMA; CALIBRATION; CLINICAL ARTICLE; COHORT ANALYSIS; COMPUTER MODEL; COMPUTER SIMULATION; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE PREDISPOSITION; DISEASE SEVERITY; FEMALE; HUMAN; INFLAMMATION; INFORMATION PROCESSING; INJURY SCALE; INTENSIVE CARE UNIT; LENGTH OF STAY; MALE; MATHEMATICAL COMPUTING; MATHEMATICAL MODEL; MORTALITY; MULTIPLE ORGAN FAILURE; ORDINARY DIFFERENTIAL EQUATION MODEL; OUTCOME ASSESSMENT; PATIENT SELECTION; PHENOTYPE; PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; REPRODUCIBILITY; SENSITIVITY ANALYSIS; SINGLE NUCLEOTIDE POLYMORPHISM; SURVIVOR; VALIDATION STUDY; VIRTUAL CLINICAL POPULATION; ANIMAL; PATHOPHYSIOLOGY; PHYSIOLOGY; STATISTICAL MODEL;

ANIMALS; COHORT STUDIES; COMPUTER SIMULATION; HUMANS; INTERLEUKIN-6; MODELS, STATISTICAL; WOUNDS, NONPENETRATING;

EID: 84929500900     PISSN: 19466234     EISSN: 19466242     Source Type: Journal    
DOI: 10.1126/scitranslmed.aaa3636     Document Type: Article

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