Central role for MCP-1/CCL2 in injury-induced inflammation revealed by in vitro, in silico, and clinical studies

PLoS ONE

Volumn 8, Issue 12, 2013, Pages

  Ziraldo, Cordelia ^a,c   Vodovotz, Yoram ^a,b   Namas, Rami A ^a   Almahmoud, Khalid ^a   Tapias, Victor ^a   Mi, Qi ^a,b   Barclay, Derek ^a   Jefferson, Bahiyyah S ^a   Chen, Guoqiang ^a,d   Billiar, Timothy R ^a,b   Zamora, Ruben ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b MCGOWAN INSTITUTE FOR REGENERATIVE MEDICINE   (United States)

^c CARNEGIE MELLON UNIVERSITY   (United States)

^d TONGJI UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; GAMMA INTERFERON INDUCIBLE PROTEIN 10; GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 17; INTERLEUKIN 1ALPHA; INTERLEUKIN 1BETA; INTERLEUKIN 2; INTERLEUKIN 4; INTERLEUKIN 5; INTERLEUKIN 6; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR ALPHA; VASCULOTROPIN;

ADULT; AGED; ANIMAL CELL; ARTICLE; ARTIFICIAL VENTILATION; BLUNT TRAUMA; CELL HYPOXIA; CLINICAL ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; CYTOKINE RELEASE; FEMALE; HEMORRHAGIC SHOCK; HUMAN; IN VITRO STUDY; INFLAMMATION; INTENSIVE CARE UNIT; LENGTH OF STAY; LIVER CELL CULTURE; MALE; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; SURVIVOR;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CELL HYPOXIA; CHEMOKINE CCL2; DISEASE-FREE SURVIVAL; FEMALE; HEP G2 CELLS; HEPATOCYTES; HUMANS; INFLAMMATION; INTERLEUKIN-1ALPHA; MALE; MICE; MICE, KNOCKOUT; MIDDLE AGED; SHOCK, HEMORRHAGIC; SURVIVAL RATE; WOUNDS AND INJURIES;

EID: 84891797164     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0079804     Document Type: Article

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