Attrition of TCR Vα7.2+ CD161++ MAIT cells in HIV-tuberculosis co-infection is associated with elevated levels of PD-1 expression

PLoS ONE

Volumn 10, Issue 4, 2015, Pages

  Saeidi, Alireza ^a   Tien Tien, Vicky L ^a   Al Batran, Rami ^a   Al Darraji, Haider A ^a   Tan, Hong Y ^a   Yong, Yean K ^a   Ponnampalavanar, Sasheela ^a   Barathan, Muttiah ^a   Rukumani, Devi V ^a   Ansari, Abdul W ^a   Velu, Vijayakumar ^b   Kamarulzaman, Adeeba ^a   Larsson, Marie ^c   Shankar, Esaki M ^a  

^a UNIVERSITY OF MALAYA   (Malaysia)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c LINKÖPING UNIVERSITY   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIRETROVIRUS AGENT; CD103 ANTIGEN; CD161 ANTIGEN; CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR5; CHEMOKINE RECEPTOR CCR6; PROGRAMMED DEATH 1 RECEPTOR; T LYMPHOCYTE RECEPTOR; TUBERCULOSTATIC AGENT; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; CCR6 PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; NATURAL KILLER CELL LECTIN LIKE RECEPTOR SUBFAMILY B; PDCD1 PROTEIN, HUMAN;

ADULT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL SURFACE; CLINICAL ARTICLE; CONTROLLED STUDY; CROSS-SECTIONAL STUDY; FEMALE; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; MALE; MIXED INFECTION; MUCOSAL ASSOCIATED INVARIANT T CELL; MUCOSAL IMMUNITY; PROTEIN EXPRESSION; T LYMPHOCYTE; TUBERCULOSIS; CELL COUNT; COINFECTION; CYTOLOGY; DRUG EFFECTS; GENE EXPRESSION REGULATION; HIV INFECTIONS; IMMUNOLOGY; METABOLISM; PHENOTYPE;

HUMAN IMMUNODEFICIENCY VIRUS 1;

ADULT; ANTI-HIV AGENTS; ANTITUBERCULAR AGENTS; CD8-POSITIVE T-LYMPHOCYTES; CELL COUNT; COINFECTION; CROSS-SECTIONAL STUDIES; FEMALE; GENE EXPRESSION REGULATION; HIV INFECTIONS; HUMANS; MALE; NK CELL LECTIN-LIKE RECEPTOR SUBFAMILY B; PHENOTYPE; PROGRAMMED CELL DEATH 1 RECEPTOR; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, CCR6; TUBERCULOSIS;

EID: 84929492879     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0124659     Document Type: Article

References (35)

1. Greenspan D, Greenspan JS. HIV-related oral disease. Lancet. 1996; 348(9029):729-33. Epub 1996/09/14. doi: S0140-6736(96)02308-2 [pii] doi: 10.1016/S0140-6736(96)02308-2 PMID: 8806295.
2. Djoba Siawaya JF, Ruhwald M, Eugen-Olsen J, Walzl G. Correlates for disease progression and prognosis during concurrent HIV/TB infection. Int J Infect Dis. 2007; 11(4):289-99. Epub 2007/04/21. doi: S1201-9712(07)00040-9 [pii] doi: 10.1016/j.ijid.2007.02.001 PMID: 17446108.
3. Geldmacher C, Schuetz A, Ngwenyama N, Casazza JP, Sanga E, Saathoff E, et al. Early depletion of Mycobacterium tuberculosis-specific T helper 1 cell responses after HIV-1 infection. J Infect Dis. 2008; 198(11):1590-8. Epub 2008/11/13. doi: 10.1086/593017 PMID: 19000013; PubMed Central PMCID: PMC2650495.
4. Shankar EM, Vignesh R, Ellegard R, Barathan M, Chong YK, Bador MK, et al. HIV-Mycobacterium tuberculosis co-infection: a 'danger-couple model' of disease pathogenesis. Pathog Dis. 2014; 70-(2):110-8. Epub 2013/11/12. doi: 10.1111/2049-632X.12108 PMID: 24214523.
5. Sonnenberg P, Glynn JR, Fielding K, Murray J, Godfrey-Faussett P, Shearer S. How soon after infection with HIV does the risk of tuberculosis start to increase? A retrospective cohort study in South African gold miners. J Infect Dis. 2005; 191(2):150-8. Epub 2004/12/21. doi: JID33039 [pii] doi: 10.1086/426827 PMID: 15609223.
6. Sutherland R, Yang H, Scriba TJ, Ondondo B, Robinson N, Conlon C, et al. Impaired IFN-gamma-secreting capacity in mycobacterial antigen-specific CD4 T cells during chronic HIV-1 infection despite long-term HAART. AIDS. 2006; 20(6):821-9. Epub 2006/03/22. doi: 10.1097/01.aids.0000218545.31716.a4 00002030-200604040-00005 [pii]. PMID: 16549965.
7. Le Bourhis L, Martin E, Peguillet I, Guihot A, Froux N, Core M, et al. Antimicrobial activity of mucosal-associated invariant T cells. Nat Immunol. 2010; 11(8):701-8. Epub 2010/06/29. doi: 10.1038/ni.1890 ni.1890 [pii]. PMID: 20581831.
8. Ussher JE, Klenerman P, Willberg CB. Mucosal-associated invariant T-cells: new players in anti-bacterial immunity. Front Immunol. 2014; 5:450. Epub 2014/10/24. doi: 10.3389/fimmu.2014.00450 PMID: 25339949; PubMed Central PMCID: PMC4189401.
9. Billerbeck E, Kang YH, Walker L, Lockstone H, Grafmueller S, Fleming V, et al. Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties. Proc Natl Acad Sci U S A. 2010; 107(7):3006-11. Epub 2010/02/06. doi: 10.1073/pnas.0914839107 0914839107 [pii]. PMID: 20133607; PubMed Central PMCID: PMC2840308.
10. Huang S, Martin E, Kim S, Yu L, Soudais C, Fremont DH, et al. MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution. Proc Natl Acad Sci U S A. 2009; 106-(20):8290-5. Epub 2009/05/07. doi: 10.1073/pnas.0903196106 0903196106 [pii]. PMID: 19416870; PubMed Central PMCID: PMC2688861.
11. Dusseaux M, Martin E, Serriari N, Peguillet I, Premel V, Louis D, et al. Human MAIT cells are xenobiotic-resistant, tissue-targeted, CD161hi IL-17-secreting T cells. Blood. 2011; 117(4):1250-9. Epub 2010/11/19. doi: 10.1182/blood-2010-08-303339 blood-2010-08-303339 [pii]. PMID: 21084709.
12. Martin E, Treiner E, Duban L, Guerri L, Laude H, Toly C, et al. Stepwise development of MAIT cells in mouse and human. PLoS Biol. 2009; 7(3):e54. Epub 2009/03/13. doi: 10.1371/journal.pbio.1000054 08-PLBI-RA-3994 [pii]. PMID: 19278296; PubMed Central PMCID: PMC2653554.
13. Lanier LL, Chang C, Phillips JH. Human NKR-P1A. A disulfide-linked homodimer of the C-type lectin superfamily expressed by a subset of NK and T lymphocytes. J Immunol. 1994; 153(6):2417-28. Epub 1994/09/15. PMID: 8077657.
14. Fergusson JR, Smith KE, Fleming VM, Rajoriya N, Newell EW, Simmons R, et al. CD161 Defines a Transcriptional and Functional Phenotype across Distinct Human T Cell Lineages. Cell Rep. 2014; 9-(3):1075-88. Epub 2014/12/02. doi: 10.1016/j.celrep.2014.09.045 S2211-1247(14)00828-6 [pii]. PMID: 25437561; PubMed Central PMCID: PMC4250839.
15. Gold MC, Cerri S, Smyk-Pearson S, Cansler ME, Vogt TM, Delepine J, et al. Human mucosal associated invariant T cells detect bacterially infected cells. PLoS Biol. 2010; 8(6):e1000407. Epub 2010/07/09. doi: 10.1371/journal.pbio.1000407 PMID: 20613858; PubMed Central PMCID: PMC2893946.
16. Maggi L, Santarlasci V, Capone M, Peired A, Frosali F, Crome SQ, et al. CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC. Eur J Immunol. 2010; 40(8):2174-81. Epub 2010/05/21. doi: 10.1002/eji.200940257 PMID: 20486123.
17. Chung DR, Kasper DL, Panzo RJ, Chitnis T, Grusby MJ, Sayegh MH, et al. CD4+ T cells mediate abscess formation in intra-abdominal sepsis by an IL-17-dependent mechanism. J Immunol. 2003; 170-(4):1958-63. Epub 2003/02/08. PMID: 12574364.
18. Brand S, Beigel F, Olszak T, Zitzmann K, Eichhorst ST, Otte JM, et al. IL-22 is increased in active Crohn's disease and promotes proinflammatory gene expression and intestinal epithelial cell migration. Am J Physiol Gastrointest Liver Physiol. 2006; 290(4):G827-38. Epub 2006/03/16. doi: 290/4/G827 [pii] doi: 10.1152/ajpgi.00513.2005 PMID: 16537974.
19. Walker LJ, Kang YH, Smith MO, Tharmalingham H, Ramamurthy N, Fleming VM, et al. Human MAIT and CD8alphaalpha cells develop from a pool of type-17 precommitted CD8+ T cells. Blood. 2012; 119-(2):422-33. Epub 2011/11/17. doi: 10.1182/blood-2011-05-353789 blood-2011-05-353789 [pii]. PMID: 22086415; PubMed Central PMCID: PMC3257008.
20. Le Bourhis L, Guerri L, Dusseaux M, Martin E, Soudais C, Lantz O. Mucosal-associated invariant T cells: unconventional development and function. Trends Immunol. 2011; 32(5):212-8. Epub 2011/04/05. doi: 10.1016/j.it.2011.02.005 S1471-4906(11)00040-8 [pii]. PMID: 21459674.
21. Reantragoon R, Corbett AJ, Sakala IG, Gherardin NA, Furness JB, Chen Z, et al. Antigen-loaded MR1 tetramers define T cell receptor heterogeneity in mucosal-associated invariant T cells. J Exp Med. 2013; 210(11):2305-20. Epub 2013/10/09. doi: 10.1084/jem.20130958 jem.20130958 [pii]. PMID: 24101382; PubMed Central PMCID: PMC3804952.
22. Fergusson JR, Fleming VM, Klenerman P. CD161-expressing human T cells. Front Immunol. 2011; 2:36. Epub 2011/01/01. doi: 10.3389/fimmu.2011.00036 PMID: 22566826; PubMed Central PMCID: PMC3342360.
23. Kurioka A, Ussher JE, Cosgrove C, Clough C, Fergusson JR, Smith K, et al. MAIT cells are licensed through granzyme exchange to kill bacterially sensitized targets. Mucosal Immunol. 2014. Epub 2014/10/02. doi: 10.1038/mi.2014.81 mi201481 [pii]. PMID: 25269706.
24. Pawlowski A, Jansson M, Skold M, Rottenberg ME, Kallenius G. Tuberculosis and HIV co-infection. PLoS Pathog. 2012; 8(2):e1002464. Epub 2012/03/01. doi: 10.1371/journal.ppat.1002464 PPATHOGENS-D-11-01902 [pii]. PMID: 22363214; PubMed Central PMCID: PMC3280977.
25. Wong EB, Akilimali NA, Govender P, Sullivan ZA, Cosgrove C, Pillay M, et al. Low levels of peripheral CD161++CD8+ mucosal associated invariant T (MAIT) cells are found in HIV and HIV/TB co-infection. PLoS One. 2013; 8(12):e83474. Epub 2014/01/07. doi: 10.1371/journal.pone.0083474 PONE-D-13-28479 [pii]. PMID: 24391773; PubMed Central PMCID: PMC3877057.
26. Leeansyah E, Ganesh A, Quigley MF, Sonnerborg A, Andersson J, Hunt PW, et al. Activation, exhaustion, and persistent decline of the antimicrobial MR1-restricted MAIT-cell population in chronic HIV-1 infection. Blood. 2013; 121(7):1124-35. Epub 2012/12/18. doi: 10.1182/blood-2012-07-445429 blood-2012-07-445429 [pii]. PMID: 23243281; PubMed Central PMCID: PMC3575756.
27. Fernandez CS, Amarasena T, Kelleher AD, Rossjohn J, McCluskey J, Godfrey DI, et al. MAIT cells are depleted early but retain functional cytokine expression in HIV infection. Immunol Cell Biol. 2014. Epub 2014/10/29. doi: 10.1038/icb.2014.91 icb201491 [pii]. PMID: 25348935.
28. Cosgrove C, Ussher JE, Rauch A, Gartner K, Kurioka A, Huhn MH, et al. Early and nonreversible decrease of CD161++ /MAIT cells in HIV infection. Blood. 2013; 121(6):951-61. Epub 2012/12/21. doi: 10.1182/blood-2012-06-436436 blood-2012-06-436436 [pii]. PMID: 23255555; PubMed Central PMCID: PMC3567342.
29. Gold MC, Lewinsohn DM. Mucosal associated invariant T cells and the immune response to infection. Microbes and Infection. 2011; 13(8):742-8.
30. Carlyle JR, Jamieson AM, Gasser S, Clingan CS, Arase H, Raulet DH. Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci U S A. 2004; 101(10):3527-32. Epub 2004/03/03. doi: 10.1073/pnas.0308304101 PMID: 0308304101 [pii]. 14990792; PubMed Central PMCID: PMC373496.
31. Trautmann L, Janbazian L, Chomont N, Said EA, Gimmig S, Bessette B, et al. Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction. Nat Med. 2006; 12-(10):1198-202. Epub 2006/08/19. doi: nm1482 [pii] doi: 10.1038/nm1482 PMID: 16917489.
32. Day CL, Kaufmann DE, Kiepiela P, Brown JA, Moodley ES, Reddy S, et al. PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression. Nature. 2006; 443-(7109):350-4. Epub 2006/08/22. doi: nature05115 [pii] doi: 10.1038/nature05115 PMID: 16921384.
33. Jiang J, Wang X, An H, Yang B, Cao Z, Liu Y, et al. Mucosal-associated invariant T-cell function is modulated by programmed death-1 signaling in patients with active tuberculosis. Am J Respir Crit Care Med. 2014; 190(3):329-39. Epub 2014/07/01. doi: 10.1164/rccm.201401-0106OC PMID: 24977786.
34. Lecureuil C, Combadiere B, Mazoyer E, Bonduelle O, Samri A, Autran B, et al. Trapping and apoptosis of novel subsets of memory T lymphocytes expressing CCR6 in the spleen of HIV-infected patients. Blood. 2007; 109(9):3649-57. Epub 2007/01/02. doi: blood-2006-01-035717 [pii] doi: 10.1182/blood-2006-01-035717 PMID: 17197436.
35. Berger EA, Murphy PM, Farber JM. Chemokine receptors as HIV-1 coreceptors: roles in viral entry, tropism, and disease. Annual review of immunology. 1999; 17(1):657-700.