MR1 antigen presentation to mucosal-associated invariant T cells was highly conserved in evolution

Proceedings of the National Academy of Sciences of the United States of America

Volumn 106, Issue 20, 2009, Pages 8290-8295

  Huang, Shouxiong ^a   Martin, Emmanuel ^b   Kim, Sojung ^a   Yu, Lawrence ^a   Soudais, Claire ^b   Fremont, Daved H ^a   Lantz, Olivier ^b   Hansen, Ted H ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b PSL RESEARCH UNIVERSITY   (France)

Author keywords

[No Author keywords available]

Indexed keywords

HLA B ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1B MR1; RECOMBINANT ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL ACTIVATION; CELL CLONING; COMMENSAL; CONTROLLED STUDY; CROSS REACTION; FEMALE; GENE; GENE CONTROL; GENE EXPRESSION; HUMAN; HUMAN CELL; HYBRIDOMA CELL CULTURE; LIGAND BINDING; MAJOR HISTOCOMPATIBILITY COMPLEX; MICROFLORA; MOLECULAR EVOLUTION; MOUSE; MR1 GENE; MUCOSAL IMMUNITY; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; ORTHOLOGY; PRIORITY JOURNAL; T LYMPHOCYTE;

ANIMALS; ANTIGEN PRESENTATION; CELL LINE; CROSS REACTIONS; EVOLUTION; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; IMMUNITY, INNATE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SUBSETS; MICE; MOLECULAR SEQUENCE DATA; MUCOUS MEMBRANE; SPECIES SPECIFICITY; T-LYMPHOCYTES;

MAMMALIA;

EID: 66249125354     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.0903196106     Document Type: Article

References (32)

1. Medzhitov R (2001) Toll-like receptors and innate immunity. Nat Rev Immunol 1:135-145.
2. Matzinger P (2002) The danger model: A renewed sense of self. Science 296:301-305.
3. Trinchieri G, Sher A (2007) Cooperation of Toll-like receptor signals in innate immune defence. Nat Rev Immunol 7:179-190.
4. Bendelac A, Bonneville M, Kearney JF (2001) Autoreactivity by design: Innate B and T lymphocytes. Nat Rev Immunol 1:177-186.
5. Colmone A, Wang CR (2006) H2-M3-restricted T cell response to infection. Microbes Infect 8:2277-2283.
6. Kawachi I, Maldonado J, Strader C, Gilfillan S (2006) MR1-restricted V alpha 19i mucosal-associated invariant T cells are innate T cells in the gut lamina propria that provide a rapid and diverse cytokine response. J Immunol 176:1618-1627.
7. Treiner E, et al. (2005) Mucosal-associated invariant T (MAIT) cells: An evolutionarily conserved T cell subset. Microbes Infect 7:552-559.
8. Martin E, et al. (2009) Stepwise development of MAIT cells in mouse and human. PLoS Biol 7:e54.
9. Tilloy F, et al. (1999) An invariant T cell receptor alpha chain defines a novel TAP-independent major histocompatibility complex class Ib-restricted alpha/beta T cell subpopulation in mammals. J Exp Med 189:1907-1921.
10. Croxford JL, et al. (2006) Invariant V(alpha)19i T cells regulate autoimmune inflammation. Nat Immunol 7:987-994.
11. Treiner E, et al. (2003) Selection of evolutionarily conserved mucosal-associated invariant T cells by MR1. Nature 422:164-169.
12. Huang S, et al. (2008) MR1 uses an endocytic pathway to activate mucosal-associated invariant T cells. J Exp Med 205:1201-1211.
13. Riegert P, Wanner V, Bahram S (1998) Genomics, isoforms, expression, and phylogeny of the MHC class I-related MR1 gene. J Immunol 161:4066-4077.
14. Doyle CK, et al. (2003) Hyperconservation of the N-formyl peptide-binding site of M3: Evidence that M3 is an old eutherian molecule with conserved recognition of a pathogen-associated molecular pattern. J Immunol 171:836-844.
15. Knapp LA, Cadavid LF, Watkins DI (1998) The MHC-E locus is the most well conserved of all known primate class I histocompatibility genes. J Immunol 160:189-196.
16. Huang S, et al. (2005) Evidence for MR1 antigen presentation to mucosal-associated invariant T cells. J Biol Chem 280:21183-21193.
17. Hansen TH, Huang S, Arnold PL, Fremont DH (2007) Patterns of nonclassical MHC antigen presentation. Nat Immunol 8:563-568.
18. Humphrey W, Dalke A, Schulten K (1996) VMD: Visual molecular dynamics. J Mol Graphics 14:33-38
19. Rudolph MG, Stanfield RL, Wilson IA (2006) How TCRs bind MHCs, peptides, and coreceptors. Annu Rev Immunol 24:419-466.
20. Porcelli S, Yockey CE, Brenner MB, Balk SP (1993) Analysis of T cell antigen receptor (TCR) expression by human peripheral blood CD4-8- alpha/beta T cells demonstrates preferential use of several V beta genes and an invariant TCR alpha chain. J Exp Med 178:1-16.
21. Miley MJ, et al. (2003) Biochemical features of the MHC-related protein 1 consistent with an immunological function. J Immunol 170:6090-6098.
22. Suri A, et al. (2003) Specificity of peptide selection by antigen-presenting cells homozygous or heterozygous for expression of class II MHC molecules: The lack of competition. Proc Natl Acad Sci USA 100:5330-5335.
23. Schumann J, et al. (2005) Targeted expression of human CD1d in transgenic mice reveals independent roles for thymocytes and thymic APCs in positive and negative selection of Valpha14i NKT cells. J Immunol 175:7303-7310.
24. Kjer-Nielsen L, et al. (2006) A structural basis for selection and cross-species reactivity of the semi-invariant NKT cell receptor in CD1d/glycolipid recognition. J Exp Med 203:661-673.
25. Brossay L, et al. (1998) CD1d-mediated recognition of an alpha-galactosylceramide by natural killer T cells is highly conserved through mammalian evolution. J Exp Med 188:1521-1528.
26. Kurepa Z, Hasemann CA, Forman J (1998) Qa-1b binds conserved class I leader peptides derived from several mammalian species. J Exp Med 188:973-978.
27. Mattner J, et al. (2005) Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections. Nature 434:525-529.
28. Soloski MJ,Metcalf ES (2001) The involvement of class Ib molecules in the host response to infection with Salmonella and its relevance to autoimmunity. Microbes Infect 3:1249-1259.
29. Rodgers JR, Cook RG (2005) MHC class Ib molecules bridge innate and acquired immunity. Nat Rev Immunol 5:459-471.
30. Lenz LL, Bevan MJ (1997) CTL responses to H2-M3-restricted Listeria epitopes. Immunol Rev 158:115-121.
31. Bendelac A, Savage PB, Teyton L (2007) The biology of NKT cells. Annu Rev Immunol 25:297-336.
32. Bennett-Lovsey RM, Herbert AD, Sternberg MJ, Kelley LA (2008) Exploring the extremes of sequence/structure space with ensemble fold recognition in the program Phyre. Proteins 70:611-625.