Aging-related anatomical and biochemical changes in lymphatic collectors impair lymph transport, fluid homeostasis, and pathogen clearance

Aging Cell

Volumn 14, Issue 4, 2015, Pages 582-594

  Zolla, Valerio ^a   Nizamutdinova, Irina Tsoy ^b   Scharf, Brian ^a   Clement, Cristina C ^a   Maejima, Daisuke ^b,c   Akl, Tony ^d   Nagai, Takashi ^b,c   Luciani, Paola ^e   Leroux, Jean Christophe ^e   Halin, Cornelia ^e   Stukes, Sabriya ^a   Tiwari, Sangeeta ^a   Casadevall, Arturo ^a   Jacobs, William R ^a   Entenberg, David ^a   Zawieja, David C ^b   Condeelis, John ^a   Fooksman, David R ^a   Gashev, Anatoliy A ^b   Santambrogio, Laura ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b TEXAS A M COLLEGE OF MEDICINE   (United States)

^c SHINSHU UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d Texas A M University   (United States)

^e ETH ZURICH   (Switzerland)

Author keywords

Aging; Lymphatics; Mass spectrometry; Oxidative stress; Proteomics

Indexed keywords

GAP JUNCTION PROTEIN; PROTEOME; SCLEROPROTEIN;

AGING; AMINO ACID SEQUENCE; ANIMAL; C57BL MOUSE; CHEMISTRY; ENDOTHELIUM CELL; FISCHER 344 RAT; GAP JUNCTION; GENETICS; GLYCOCALYX; GLYCOSYLATION; GRAM POSITIVE INFECTION; HOMEOSTASIS; LYMPH; LYMPH NODE; LYMPH VESSEL; MALE; MESENTERY; METABOLISM; MICROBIOLOGY; MOLECULAR GENETICS; MOUSE; MYCOBACTERIUM SMEGMATIS; PHYSIOLOGY; RAT; SMOOTH MUSCLE CELL; STAPHYLOCOCCUS AUREUS; TIME LAPSE IMAGING; ULTRASTRUCTURE;

AGING; AMINO ACID SEQUENCE; ANIMALS; CONNEXINS; ENDOTHELIAL CELLS; EXTRACELLULAR MATRIX PROTEINS; GAP JUNCTIONS; GLYCOCALYX; GLYCOSYLATION; GRAM-POSITIVE BACTERIAL INFECTIONS; HOMEOSTASIS; LYMPH; LYMPH NODES; LYMPHATIC VESSELS; MALE; MESENTERY; MICE; MICE, INBRED C57BL; MOLECULAR SEQUENCE DATA; MYCOBACTERIUM SMEGMATIS; MYOCYTES, SMOOTH MUSCLE; PROTEOME; RATS; RATS, INBRED F344; STAPHYLOCOCCUS AUREUS; TIME-LAPSE IMAGING;

EID: 84929439729     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12330     Document Type: Article

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