-
1
-
-
84984930451
-
Mutations of lrtomt, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans
-
Ahmed ZM, Masmoudi S, Kalay E, Belyantseva IA, Mosrati MA, Collin RW, Riazuddin S, Hmani-Aifa M, Venselaar H, Kawar MN, Tlili A, van der Zwaag B, Khan SY, Ayadi L, Riazuddin SA, Morell RJ, Griffith AJ, Charfedine I, Caylan R, Oostrik J, et al. (2008) Mutations of LRTOMT, a fusion gene with alternative reading frames, cause nonsyndromic deafness in humans. Nat Genet 40:1335–1340.
-
(2008)
Nat Genet
, vol.40
, pp. 1335-1340
-
-
Ahmed, Z.M.1
Masmoudi, S.2
Kalay, E.3
Belyantseva, I.A.4
Mosrati, M.A.5
Collin, R.W.6
Riazuddin, S.7
Hmani-Aifa, M.8
Venselaar, H.9
Kawar, M.N.10
Tlili, A.11
Van Der Zwaag, B.12
Khan, S.Y.13
Ayadi, L.14
Riazuddin, S.A.15
Morell, R.J.16
Griffith, A.J.17
Charfedine, I.18
Caylan, R.19
Oostrik, J.20
more..
-
2
-
-
77958471357
-
Differential expression analysis for sequence count data
-
Anders S, Huber W (2010) Differential expression analysis for sequence count data. Genome Biol 11:R106.
-
(2010)
Genome Biol
, vol.11
, pp. R106
-
-
Anders, S.1
Huber, W.2
-
3
-
-
0030751937
-
Characterization of unconventional myo6, the human homologue of the gene responsible for deafness in snell’s waltzer mice
-
Avraham KB, Hasson T, Sobe T, Balsara B, Testa JR, Skvorak AB, Morton CC, Copeland NG, Jenkins NA (1997) Characterization of unconventional MYO6, the human homologue of the gene responsible for deafness in Snell’s waltzer mice. Hum Mol Genet 6:1225–1231.
-
(1997)
Hum Mol Genet
, vol.6
, pp. 1225-1231
-
-
Avraham, K.B.1
Hasson, T.2
Sobe, T.3
Balsara, B.4
Testa, J.R.5
Skvorak, A.B.6
Morton, C.C.7
Copeland, N.G.8
Jenkins, N.A.9
-
4
-
-
67651236958
-
Repair of the vestibular system via adenovector delivery of atoh1: A potential treatment for balance disorders
-
Baker K, Brough DE, Staecker H (2009) Repair of the vestibular system via adenovector delivery of Atoh1: a potential treatment for balance disorders. Adv Otorhinolaryngol 66:52–63.
-
(2009)
Adv Otorhinolaryngol
, vol.66
, pp. 52-63
-
-
Baker, K.1
Brough, D.E.2
Staecker, H.3
-
5
-
-
0034672784
-
Expression and localization of prestin and the sugar transporter glut-5 during development of electromotility in cochlear outer hair cells
-
RC116
-
Belyantseva IA, Adler HJ, Curi R, Frolenkov GI, Kachar B (2000) Expression and localization of prestin and the sugar transporter GLUT-5 during development of electromotility in cochlear outer hair cells. J Neurosci 20:RC116.
-
(2000)
J Neurosci
, vol.20
-
-
Belyantseva, I.A.1
Adler, H.J.2
Curi, R.3
Frolenkov, G.I.4
Kachar, B.5
-
6
-
-
0030669218
-
Math1 is essential for genesis of cerebellar granule neurons
-
Ben-Arie N, Bellen HJ, Armstrong DL, McCall AE, Gordadze PR, Guo Q, Matzuk MM, Zoghbi HY (1997) Math1 is essential for genesis of cerebellar granule neurons. Nature 390:169–172.
-
(1997)
Nature
, vol.390
, pp. 169-172
-
-
Ben-Arie, N.1
Bellen, H.J.2
Armstrong, D.L.3
McCall, A.E.4
Gordadze, P.R.5
Guo, Q.6
Matzuk, M.M.7
Zoghbi, H.Y.8
-
7
-
-
0001677717
-
Controlling the false discovery rate: A practical and powerful approach to multiple testing
-
Benjamini Y, Hochberg Y (1995) Controlling the false discovery rate: a practical and powerful approach to multiple testing. J R Stat Soc Ser B 57:289–300.
-
(1995)
J R Stat Soc Ser B
, vol.57
, pp. 289-300
-
-
Benjamini, Y.1
Hochberg, Y.2
-
8
-
-
10744222330
-
Claudin 14 knockout mice, a model for autosomal recessive deafness dfnb29, are deaf due to cochlear hair cell degeneration
-
Ben-Yosef T, Belyantseva IA, Saunders TL, Hughes ED, Kawamoto K, Van Itallie CM, Beyer LA, Halsey K, Gardner DJ, Wilcox ER, Rasmussen J, Anderson JM, Dolan DF, Forge A, Raphael Y, Camper SA, Friedman TB (2003) Claudin 14 knockout mice, a model for autosomal recessive deafness DFNB29, are deaf due to cochlear hair cell degeneration. Hum Mol Genet 12:2049–2061.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 2049-2061
-
-
Ben-Yosef, T.1
Belyantseva, I.A.2
Saunders, T.L.3
Hughes, E.D.4
Kawamoto, K.5
Van Itallie, C.M.6
Beyer, L.A.7
Halsey, K.8
Gardner, D.J.9
Wilcox, E.R.10
Rasmussen, J.11
Anderson, J.M.12
Dolan, D.F.13
Forge, A.14
Raphael, Y.15
Camper, S.A.16
Friedman, T.B.17
-
9
-
-
0033546004
-
Math1: An essential gene for the generation of inner ear hair cells
-
Bermingham NA, Hassan BA, Price SD, Vollrath MA, Ben-Arie N, Eatock RA, Bellen HJ, Lysakowski A, Zoghbi HY (1999) Math1: an essential gene for the generation of inner ear hair cells. Science 284:1837–1841.
-
(1999)
Science
, vol.284
, pp. 1837-1841
-
-
Bermingham, N.A.1
Hassan, B.A.2
Price, S.D.3
Vollrath, M.A.4
Ben-Arie, N.5
Eatock, R.A.6
Bellen, H.J.7
Lysakowski, A.8
Zoghbi, H.Y.9
-
10
-
-
0027364073
-
Sympathetic neuroblasts undergo a developmental switch in trophic dependence
-
Birren SJ, Lo L, Anderson DJ (1993) Sympathetic neuroblasts undergo a developmental switch in trophic dependence. Development 119:597– 610.
-
(1993)
Development
, vol.119
, pp. 597-610
-
-
Birren, S.J.1
Lo, L.2
Anderson, D.J.3
-
11
-
-
84868000712
-
Somatostatin receptor types 1 and 2 in the developing mammalian cochlea
-
Bodmer D, Brand Y, Radojevic V (2012) Somatostatin receptor types 1 and 2 in the developing mammalian cochlea. Dev Neurosci 34:342–353.
-
(2012)
Dev Neurosci
, vol.34
, pp. 342-353
-
-
Bodmer, D.1
Brand, Y.2
Radojevic, V.3
-
12
-
-
33846261634
-
Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration
-
Cafaro J, Lee GS, Stone JS (2007) Atoh1 expression defines activated progenitors and differentiating hair cells during avian hair cell regeneration. Dev Dyn 236:156–170.
-
(2007)
Dev Dyn
, vol.236
, pp. 156-170
-
-
Cafaro, J.1
Lee, G.S.2
Stone, J.S.3
-
13
-
-
84878882559
-
Conditional deletion of atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of corti
-
Cai T, Seymour ML, Zhang H, Pereira FA, Groves AK (2013) Conditional deletion of Atoh1 reveals distinct critical periods for survival and function of hair cells in the organ of Corti. J Neurosci 33:10110–10122.
-
(2013)
J Neurosci
, vol.33
, pp. 10110-10122
-
-
Cai, T.1
Seymour, M.L.2
Zhang, H.3
Pereira, F.A.4
Groves, A.K.5
-
14
-
-
84899416729
-
The casz1/egfl7 transcriptional pathway is required for rhoa expression in vascular endothelial cells
-
Charpentier MS, Taylor JM, Conlon FL (2013) The CASZ1/Egfl7 transcriptional pathway is required for RhoA expression in vascular endothelial cells. Small GTPases 4:231–235.
-
(2013)
Small Gtpases
, vol.4
, pp. 231-235
-
-
Charpentier, M.S.1
Taylor, J.M.2
Conlon, F.L.3
-
15
-
-
0036337481
-
The role of math1 in inner ear development: Uncoupling the establishment of the sensory primordium from hair cell fate determination
-
Chen P, Johnson JE, Zoghbi HY, Segil N (2002) The role of Math1 in inner ear development: uncoupling the establishment of the sensory primordium from hair cell fate determination. Development 129:2495–2505.
-
(2002)
Development
, vol.129
, pp. 2495-2505
-
-
Chen, P.1
Johnson, J.E.2
Zoghbi, H.Y.3
Segil, N.4
-
16
-
-
73949145721
-
Microchip: Chromatin immunoprecipitation for small cell numbers
-
Dahl JA, Collas P (2009) MicroChIP: chromatin immunoprecipitation for small cell numbers. Methods Mol Biol 567:59–74.
-
(2009)
Methods Mol Biol
, vol.567
, pp. 59-74
-
-
Dahl, J.A.1
Collas, P.2
-
17
-
-
0027281992
-
Localization of calretinin mrna in rat and guinea pig inner ear by in situ hybridization using radioactive and non-radioactive probes
-
Dechesne CJ, Winsky L, Moniot B, Raymond J (1993) Localization of calretinin mRNA in rat and guinea pig inner ear by in situ hybridization using radioactive and non-radioactive probes. Hear Res 69:91–97.
-
(1993)
Hear Res
, vol.69
, pp. 91-97
-
-
Dechesne, C.J.1
Winsky, L.2
Moniot, B.3
Raymond, J.4
-
18
-
-
0026062678
-
Identification and ultrastructural localization of a calretinin-like calcium-binding protein (protein 10) in the guinea pig and rat inner ear
-
Dechesne CJ, Winsky L, Kim HN, Goping G, Vu TD, Wenthold RJ, Jacobowitz DM (1991) Identification and ultrastructural localization of a calretinin-like calcium-binding protein (protein 10) in the guinea pig and rat inner ear. Brain Res 560:139–148.
-
(1991)
Brain Res
, vol.560
, pp. 139-148
-
-
Dechesne, C.J.1
Winsky, L.2
Kim, H.N.3
Goping, G.4
Vu, T.D.5
Wenthold, R.J.6
Jacobowitz, D.M.7
-
19
-
-
33748133364
-
Differential expression of lim domainonly (lmo) genes in the developing mouse inner ear
-
Deng M, Pan L, Xie X, Gan L (2006) Differential expression of LIM domainonly (LMO) genes in the developing mouse inner ear. Gene Expr Patterns 6:857–863.
-
(2006)
Gene Expr Patterns
, vol.6
, pp. 857-863
-
-
Deng, M.1
Pan, L.2
Xie, X.3
Gan, L.4
-
20
-
-
0037069373
-
Mutations in mcoln3 associated with deafness and pigmentation defects in varitint-waddler (va) mice
-
Di Palma F, Belyantseva IA, Kim HJ, Vogt TF, Kachar B, Noben-Trauth K (2002) Mutations in Mcoln3 associated with deafness and pigmentation defects in varitint-waddler (Va) mice. Proc Natl Acad Sci U S A 99: 14994–14999.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 14994-14999
-
-
Di Palma, F.1
Belyantseva, I.A.2
Kim, H.J.3
Vogt, T.F.4
Kachar, B.5
Noben-Trauth, K.6
-
21
-
-
82755197821
-
Cisplatin ototoxicity in rat cochlear organotypic cultures
-
Ding D, He J, Allman BL, Yu D, Jiang H, Seigel GM, Salvi RJ (2011) Cisplatin ototoxicity in rat cochlear organotypic cultures. Hear Res 282:196– 203.
-
(2011)
Hear Res
, vol.282
, pp. 196-203
-
-
Ding, D.1
He, J.2
Allman, B.L.3
Yu, D.4
Jiang, H.5
Seigel, G.M.6
Salvi, R.J.7
-
22
-
-
0028171296
-
Alpha 9: An acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells
-
Elgoyhen AB, Johnson DS, Boulter J, Vetter DE, Heinemann S (1994) Alpha 9: an acetylcholine receptor with novel pharmacological properties expressed in rat cochlear hair cells. Cell 79:705–715.
-
(1994)
Cell
, vol.79
, pp. 705-715
-
-
Elgoyhen, A.B.1
Johnson, D.S.2
Boulter, J.3
Vetter, D.E.4
Heinemann, S.5
-
23
-
-
0035852933
-
Boulter j (2001) alpha10: A determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells
-
Elgoyhen AB, Vetter DE, Katz E, Rothlin CV, Heinemann SF, Boulter J (2001) alpha10: a determinant of nicotinic cholinergic receptor function in mammalian vestibular and cochlear mechanosensory hair cells. Proc Natl Acad Sci U S A 98:3501–3506.
-
Proc Natl Acad Sci U S A
, vol.98
, pp. 3501-3506
-
-
Elgoyhen, A.B.1
Vetter, D.E.2
Katz, E.3
Rothlin, C.V.4
Heinemann, S.F.5
-
24
-
-
15844384249
-
Role of transcription factors brn-3.1 and brn-3.2 in auditory and visual system development
-
Erkman L, McEvilly RJ, Luo L, Ryan AK, Hooshmand F, O’Connell SM, Keithley EM, Rapaport DH, Ryan AF, Rosenfeld MG (1996) Role of transcription factors Brn-3.1 and Brn-3.2 in auditory and visual system development. Nature 381:603–606.
-
(1996)
Nature
, vol.381
, pp. 603-606
-
-
Erkman, L.1
McEvilly, R.J.2
Luo, L.3
Ryan, A.K.4
Hooshmand, F.5
O’Connell, S.M.6
Keithley, E.M.7
Rapaport, D.H.8
Ryan, A.F.9
Rosenfeld, M.G.10
-
26
-
-
0141954045
-
A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles
-
Goodyear RJ, Legan PK, Wright MB, Marcotti W, Oganesian A, Coats SA, Booth CJ, Kros CJ, Seifert RA, Bowen-Pope DF, Richardson GP (2003) A receptor-like inositol lipid phosphatase is required for the maturation of developing cochlear hair bundles. J Neurosci 23:9208–9219.
-
(2003)
J Neurosci
, vol.23
, pp. 9208-9219
-
-
Goodyear, R.J.1
Legan, P.K.2
Wright, M.B.3
Marcotti, W.4
Oganesian, A.5
Coats, S.A.6
Booth, C.J.7
Kros, C.J.8
Seifert, R.A.9
Bowen-Pope, D.F.10
Richardson, G.P.11
-
27
-
-
69449086147
-
Mutations in loxhd1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans
-
Grillet N, Schwander M, Hildebrand MS, Sczaniecka A, Kolatkar A, Velasco J, Webster JA, Kahrizi K, Najmabadi H, Kimberling WJ, Stephan D, Bahlo M, Wiltshire T, Tarantino LM, Kuhn P, Smith RJ, Müller U (2009) Mutations in LOXHD1, an evolutionarily conserved stereociliary protein, disrupt hair cell function in mice and cause progressive hearing loss in humans. Am J Hum Genet 85:328–337.
-
(2009)
Am J Hum Genet
, vol.85
, pp. 328-337
-
-
Grillet, N.1
Schwander, M.2
Hildebrand, M.S.3
Sczaniecka, A.4
Kolatkar, A.5
Velasco, J.6
Webster, J.A.7
Kahrizi, K.8
Najmabadi, H.9
Kimberling, W.J.10
Stephan, D.11
Bahlo, M.12
Wiltshire, T.13
Tarantino, L.M.14
Kuhn, P.15
Smith, R.J.16
Müller, U.17
-
28
-
-
0028915319
-
Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons
-
Groves AK, George KM, Tissier-Seta JP, Engel JD, Brunet JF, Anderson DJ (1995) Differential regulation of transcription factor gene expression and phenotypic markers in developing sympathetic neurons. Development 121:887–901.
-
(1995)
Development
, vol.121
, pp. 887-901
-
-
Groves, A.K.1
George, K.M.2
Tissier-Seta, J.P.3
Engel, J.D.4
Brunet, J.F.5
Anderson, D.J.6
-
29
-
-
84880262810
-
The genetics of hair cell development and regeneration
-
Groves AK, Zhang KD, Fekete DM (2013) The genetics of hair cell development and regeneration. Annu Rev Neurosci 36:361–381.
-
(2013)
Annu Rev Neurosci
, vol.36
, pp. 361-381
-
-
Groves, A.K.1
Zhang, K.D.2
Fekete, D.M.3
-
30
-
-
52949112282
-
Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer
-
Gubbels SP, Woessner DW, Mitchell JC, Ricci AJ, Brigande JV (2008) Functional auditory hair cells produced in the mammalian cochlea by in utero gene transfer. Nature 455:537–541.
-
(2008)
Nature
, vol.455
, pp. 537-541
-
-
Gubbels, S.P.1
Woessner, D.W.2
Mitchell, J.C.3
Ricci, A.J.4
Brigande, J.V.5
-
31
-
-
0026285616
-
In situ hybridization: An improved whole-mount method for xenopus embryos
-
Harland RM (1991) In situ hybridization: an improved whole-mount method for Xenopus embryos. Methods Cell Biol 36:685–695.
-
(1991)
Methods Cell Biol
, vol.36
, pp. 685-695
-
-
Harland, R.M.1
-
32
-
-
35348981795
-
Dll3 is expressed in developing hair cells in the mammalian cochlea
-
Hartman BH, Hayashi T, Nelson BR, Bermingham-McDonogh O, Reh TA (2007) Dll3 is expressed in developing hair cells in the mammalian cochlea. Dev Dyn 236:2875–2883.
-
(2007)
Dev Dyn
, vol.236
, pp. 2875-2883
-
-
Hartman, B.H.1
Hayashi, T.2
Nelson, B.R.3
Bermingham-McDonogh, O.4
Reh, T.A.5
-
33
-
-
0028787263
-
Expression in cochlea and retina of myosin viia, the gene product defective in usher syndrome type 1b
-
Hasson T, Heintzelman MB, Santos-Sacchi J, Corey DP, Mooseker MS (1995) Expression in cochlea and retina of myosin VIIa, the gene product defective in Usher syndrome type 1B. Proc Natl Acad Sci U S A 92:9815– 9819.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 9815-9819
-
-
Hasson, T.1
Heintzelman, M.B.2
Santos-Sacchi, J.3
Corey, D.P.4
Mooseker, M.S.5
-
34
-
-
0034029614
-
Autoregulation and multiple enhancers control math1 expression in the developing nervous system
-
Helms AW, Abney AL, Ben-Arie N, Zoghbi HY, Johnson JE (2000) Autoregulation and multiple enhancers control Math1 expression in the developing nervous system. Development 127:1185–1196.
-
(2000)
Development
, vol.127
, pp. 1185-1196
-
-
Helms, A.W.1
Abney, A.L.2
Ben-Arie, N.3
Zoghbi, H.Y.4
Johnson, J.E.5
-
35
-
-
33847215873
-
Lhx3, a lim domain transcription factor, is regulated by pou4f3 in the auditory but not in the vestibular system
-
Hertzano R, Dror AA, Montcouquiol M, Ahmed ZM, Ellsworth B, Camper S, Friedman TB, Kelley MW, Avraham KB (2007) Lhx3, a LIM domain transcription factor, is regulated by Pou4f3 in the auditory but not in the vestibular system. Eur J Neurosci 25:999–1005.
-
(2007)
Eur J Neurosci
, vol.25
, pp. 999-1005
-
-
Hertzano, R.1
Dror, A.A.2
Montcouquiol, M.3
Ahmed, Z.M.4
Ellsworth, B.5
Camper, S.6
Friedman, T.B.7
Kelley, M.W.8
Avraham, K.B.9
-
36
-
-
80053437834
-
Cell type-specific transcriptome analysis reveals a major role for zeb1 and mir-200b in mouse inner ear morphogenesis
-
Hertzano R, Elkon R, Kurima K, Morrisson A, Chan SL, Sallin M, Biedlingmaier A, Darling DS, Griffith AJ, Eisenman DJ, Strome SE (2011) Cell type-specific transcriptome analysis reveals a major role for Zeb1 and miR-200b in mouse inner ear morphogenesis. PLoS Genet 7:e1002309.
-
(2011)
Plos Genet
, vol.7
-
-
Hertzano, R.1
Elkon, R.2
Kurima, K.3
Morrisson, A.4
Chan, S.L.5
Sallin, M.6
Biedlingmaier, A.7
Darling, D.S.8
Griffith, A.J.9
Eisenman, D.J.10
Strome, S.E.11
-
37
-
-
58549112996
-
Bioinformatics enrichment tools: Paths toward the comprehensive functional analysis of large gene lists
-
Huang DW, Sherman BT, Lempicki RA (2009a) Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37:1–13.
-
(2009)
Nucleic Acids Res
, vol.37
, pp. 1-13
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
38
-
-
61449172037
-
Systematic and integrative analysis of large gene lists using david bioinformatics resources
-
Huang DW, Sherman BT, Lempicki RA (2009b) Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources. Nat Protoc 4:44–57.
-
(2009)
Nat Protoc
, vol.4
, pp. 44-57
-
-
Huang, D.W.1
Sherman, B.T.2
Lempicki, R.A.3
-
39
-
-
67651227632
-
Gene therapy in the inner ear using adenovirus vectors
-
Husseman J, Raphael Y (2009) Gene therapy in the inner ear using adenovirus vectors. Adv Otorhinolaryngol 66:37–51.
-
(2009)
Adv Otorhinolaryngol
, vol.66
, pp. 37-51
-
-
Husseman, J.1
Raphael, Y.2
-
40
-
-
84929312307
-
Transcription factors with conserved binding sites near atoh1 on the pou4f3 gene enhance the induction of cochlear hair cells
-
Ikeda R, Pak K, Chavez E, Ryan AF (2015) Transcription factors with conserved binding sites near ATOH1 on the POU4F3 gene enhance the induction of cochlear hair cells. Mol Neurobiol 51:672–684.
-
(2015)
Mol Neurobiol
, vol.51
, pp. 672-684
-
-
Ikeda, R.1
Pak, K.2
Chavez, E.3
Ryan, A.F.4
-
41
-
-
84898803026
-
A frameshift mutation in grxcr2 causes recessively inherited hearing loss
-
Imtiaz A, Kohrman DC, Naz S (2014) A frameshift mutation in GRXCR2 causes recessively inherited hearing loss. Hum Mutat 35:618–624.
-
(2014)
Hum Mutat
, vol.35
, pp. 618-624
-
-
Imtiaz, A.1
Kohrman, D.C.2
Naz, S.3
-
42
-
-
16244411316
-
Auditory hair cell replacement and hearing improvement by atoh1 gene therapy in deaf mammals
-
Izumikawa M, Minoda R, Kawamoto K, Abrashkin KA, Swiderski DL, Dolan DF, Brough DE, Raphael Y (2005) Auditory hair cell replacement and hearing improvement by Atoh1 gene therapy in deaf mammals. Nat Med 11:271–276.
-
(2005)
Nat Med
, vol.11
, pp. 271-276
-
-
Izumikawa, M.1
Minoda, R.2
Kawamoto, K.3
Abrashkin, K.A.4
Swiderski, D.L.5
Dolan, D.F.6
Brough, D.E.7
Raphael, Y.8
-
43
-
-
34548567099
-
Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea
-
Jacques BE, Montcouquiol ME, Layman EM, Lewandoski M, Kelley MW (2007) Fgf8 induces pillar cell fate and regulates cellular patterning in the mammalian cochlea. Development 134:3021–3029.
-
(2007)
Development
, vol.134
, pp. 3021-3029
-
-
Jacques, B.E.1
Montcouquiol, M.E.2
Layman, E.M.3
Lewandoski, M.4
Kelley, M.W.5
-
44
-
-
84879188938
-
The role of atonal transcription factors in the development of mechanosensitive cells
-
Jarman AP, Groves AK (2013) The role of atonal transcription factors in the development of mechanosensitive cells. Semin Cell Dev Biol 24:438–447.
-
(2013)
Semin Cell Dev Biol
, vol.24
, pp. 438-447
-
-
Jarman, A.P.1
Groves, A.K.2
-
45
-
-
33745700373
-
Mutations in the lipoma hmgic fusion partner-like 5 (lhfpl5) gene cause autosomal recessive nonsyndromic hearing loss
-
Kalay E, Li Y, Uzumcu A, Uyguner O, Collin RW, Caylan R, Ulubil-Emiroglu M, Kersten FF, Hafiz G, van Wijk E, Kayserili H, Rohmann E, Wagenstaller J, Hoefsloot LH, Strom TM, Nürnberg G, Baserer N, den Hollander AI, Cremers FP, Cremers CW, et al. (2006) Mutations in the lipoma HMGIC fusion partner-like 5 (LHFPL5) gene cause autosomal recessive nonsyndromic hearing loss. Hum Mutat 27:633–639.
-
(2006)
Hum Mutat
, vol.27
, pp. 633-639
-
-
Kalay, E.1
Li, Y.2
Uzumcu, A.3
Uyguner, O.4
Collin, R.W.5
Caylan, R.6
Ulubil-Emiroglu, M.7
Kersten, F.F.8
Hafiz, G.9
Van Wijk, E.10
Kayserili, H.11
Rohmann, E.12
Wagenstaller, J.13
Hoefsloot, L.H.14
Strom, T.M.15
Nürnberg, G.16
Baserer, N.17
Den Hollander, A.I.18
Cremers, F.P.19
Cremers, C.W.20
more..
-
46
-
-
0038118296
-
Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo
-
Kawamoto K, Ishimoto S, Minoda R, Brough DE, Raphael Y (2003) Math1 gene transfer generates new cochlear hair cells in mature guinea pigs in vivo. J Neurosci 23:4395–4400.
-
(2003)
J Neurosci
, vol.23
, pp. 4395-4400
-
-
Kawamoto, K.1
Ishimoto, S.2
Minoda, R.3
Brough, D.E.4
Raphael, Y.5
-
47
-
-
84055217017
-
Mechanotransduction in mouse inner ear hair cells requires transmembrane channellike genes
-
Kawashima Y, Géléoc GS, Kurima K, Labay V, Lelli A, Asai Y, Makishima T, Wu DK, Della Santina CC, Holt JR, Griffith AJ (2011) Mechanotransduction in mouse inner ear hair cells requires transmembrane channellike genes. J Clin Invest 121:4796–4809.
-
(2011)
J Clin Invest
, vol.121
, pp. 4796-4809
-
-
Kawashima, Y.1
Géléoc, G.S.2
Kurima, K.3
Labay, V.4
Lelli, A.5
Asai, Y.6
Makishima, T.7
Wu, D.K.8
Della Santina, C.C.9
Holt, J.R.10
Griffith, A.J.11
-
48
-
-
84860657802
-
Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo
-
Kelly MC, Chang Q, Pan A, Lin X, Chen P (2012) Atoh1 directs the formation of sensory mosaics and induces cell proliferation in the postnatal mammalian cochlea in vivo. J Neurosci 32:6699–6710.
-
(2012)
J Neurosci
, vol.32
, pp. 6699-6710
-
-
Kelly, M.C.1
Chang, Q.2
Pan, A.3
Lin, X.4
Chen, P.5
-
49
-
-
0037337023
-
Mutations in a new scaffold protein sans cause deafness in jackson shaker mice
-
Kikkawa Y, Shitara H, Wakana S, Kohara Y, Takada T, Okamoto M, Taya C, Kamiya K, Yoshikawa Y, Tokano H, Kitamura K, Shimizu K, Wakabayashi Y, Shiroishi T, Kominami R, Yonekawa H (2003) Mutations in a new scaffold protein Sans cause deafness in Jackson shaker mice. Hum Mol Genet 12:453–461.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 453-461
-
-
Kikkawa, Y.1
Shitara, H.2
Wakana, S.3
Kohara, Y.4
Takada, T.5
Okamoto, M.6
Taya, C.7
Kamiya, K.8
Yoshikawa, Y.9
Tokano, H.10
Kitamura, K.11
Shimizu, K.12
Wakabayashi, Y.13
Shiroishi, T.14
Kominami, R.15
Yonekawa, H.16
-
50
-
-
84896691636
-
Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity
-
Kim TH, Li F, Ferreiro-Neira I, Ho LL, Luyten A, Nalapareddy K, Long H, Verzi M, Shivdasani RA (2014) Broadly permissive intestinal chromatin underlies lateral inhibition and cell plasticity. Nature 506:511–515.
-
(2014)
Nature
, vol.506
, pp. 511-515
-
-
Kim, T.H.1
Li, F.2
Ferreiro-Neira, I.3
Ho, L.L.4
Luyten, A.5
Nalapareddy, K.6
Long, H.7
Verzi, M.8
Shivdasani, R.A.9
-
51
-
-
79952769989
-
In vivo atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development
-
Klisch TJ, Xi Y, Flora A, Wang L, Li W, Zoghbi HY (2011) In vivo Atoh1 targetome reveals how a proneural transcription factor regulates cerebellar development. Proc Natl Acad Sci U S A 108:3288–3293.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 3288-3293
-
-
Klisch, T.J.1
Xi, Y.2
Flora, A.3
Wang, L.4
Li, W.5
Zoghbi, H.Y.6
-
52
-
-
33646886593
-
Math1 target genes are enriched with evolutionarily conserved clustered e-box binding sites
-
Krizhanovsky V, Soreq L, Kliminski V, Ben-Arie N (2006) Math1 target genes are enriched with evolutionarily conserved clustered E-box binding sites. J Mol Neurosci 28:211–229.
-
(2006)
J Mol Neurosci
, vol.28
, pp. 211-229
-
-
Krizhanovsky, V.1
Soreq, L.2
Kliminski, V.3
Ben-Arie, N.4
-
53
-
-
33748910801
-
Functional redundancy of nscl-1 and neurod during development of the petrosal and vestibulocochlear ganglia
-
Krüger M, Schmid T, Krüger S, Bober E, Braun T (2006) Functional redundancy of NSCL-1 and NeuroD during development of the petrosal and vestibulocochlear ganglia. Eur J Neurosci 24:1581–1590.
-
(2006)
Eur J Neurosci
, vol.24
, pp. 1581-1590
-
-
Krüger, M.1
Schmid, T.2
Krüger, S.3
Bober, E.4
Braun, T.5
-
54
-
-
84895485132
-
The transcriptome of utricle hair cell regeneration in the avian inner ear
-
Ku YC, Renaud NA, Veile RA, Helms C, Voelker CC, Warchol ME, Lovett M (2014) The transcriptome of utricle hair cell regeneration in the avian inner ear. J Neurosci 34:3523–3535.
-
(2014)
J Neurosci
, vol.34
, pp. 3523-3535
-
-
Ku, Y.C.1
Renaud, N.A.2
Veile, R.A.3
Helms, C.4
Voelker, C.C.5
Warchol, M.E.6
Lovett, M.7
-
55
-
-
79960939324
-
In vivo neuronal subtype-specific targets of atoh1 (math1) in dorsal spinal cord
-
Lai HC, Klisch TJ, Roberts R, Zoghbi HY, Johnson JE (2011) In vivo neuronal subtype-specific targets of Atoh1 (Math1) in dorsal spinal cord. J Neurosci 31:10859–10871.
-
(2011)
J Neurosci
, vol.31
, pp. 10859-10871
-
-
Lai, H.C.1
Klisch, T.J.2
Roberts, R.3
Zoghbi, H.Y.4
Johnson, J.E.5
-
56
-
-
0033021954
-
Notch signalling pathway mediates hair cell development in mammalian cochlea
-
Lanford PJ, Lan Y, Jiang R, Lindsell C, Weinmaster G, Gridley T, Kelley MW (1999) Notch signalling pathway mediates hair cell development in mammalian cochlea. Nat Genet 21:289–292.
-
(1999)
Nat Genet
, vol.21
, pp. 289-292
-
-
Lanford, P.J.1
Lan, Y.2
Jiang, R.3
Lindsell, C.4
Weinmaster, G.5
Gridley, T.6
Kelley, M.W.7
-
57
-
-
66349126903
-
Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea
-
Lelli A, Asai Y, Forge A, Holt JR, Géléoc GS (2009) Tonotopic gradient in the developmental acquisition of sensory transduction in outer hair cells of the mouse cochlea. J Neurophysiol 101:2961–2973.
-
(2009)
J Neurophysiol
, vol.101
, pp. 2961-2973
-
-
Lelli, A.1
Asai, Y.2
Forge, A.3
Holt, J.R.4
Géléoc, G.S.5
-
58
-
-
84861858352
-
Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens
-
Lewis RM, Hume CR, Stone JS (2012) Atoh1 expression and function during auditory hair cell regeneration in post-hatch chickens. Hear Res 289: 74–85.
-
(2012)
Hear Res
, vol.289
, pp. 74-85
-
-
Lewis, R.M.1
Hume, C.R.2
Stone, J.S.3
-
59
-
-
0036638824
-
Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the barhl1 homeobox gene
-
Li S, Price SM, Cahill H, Ryugo DK, Shen MM, Xiang M (2002) Hearing loss caused by progressive degeneration of cochlear hair cells in mice deficient for the Barhl1 homeobox gene. Development 129:3523–3532.
-
(2002)
Development
, vol.129
, pp. 3523-3532
-
-
Li, S.1
Price, S.M.2
Cahill, H.3
Ryugo, D.K.4
Shen, M.M.5
Xiang, M.6
-
60
-
-
84905851547
-
Characterization of transcriptomes of cochlear inner and outer hair cells
-
Liu H, Pecka JL, Zhang Q, Soukup GA, Beisel KW, He DZ (2014) Characterization of transcriptomes of cochlear inner and outer hair cells. J Neurosci 34:11085–11095.
-
(2014)
J Neurosci
, vol.34
, pp. 11085-11095
-
-
Liu, H.1
Pecka, J.L.2
Zhang, Q.3
Soukup, G.A.4
Beisel, K.W.5
He, D.Z.6
-
61
-
-
84860683510
-
Age-dependent in vivo conversion of mouse cochlear pillar and deiters’ cells to immature hair cells by atoh1 ectopic expression
-
Liu Z, Dearman JA, Cox BC, Walters BJ, Zhang L, Ayrault O, Zindy F, Gan L, Roussel MF, Zuo J (2012) Age-dependent in vivo conversion of mouse cochlear pillar and deiters’ cells to immature hair cells by atoh1 ectopic expression. J Neurosci 32:6600–6610.
-
(2012)
J Neurosci
, vol.32
, pp. 6600-6610
-
-
Liu, Z.1
Dearman, J.A.2
Cox, B.C.3
Walters, B.J.4
Zhang, L.5
Ayrault, O.6
Zindy, F.7
Gan, L.8
Roussel, M.F.9
Zuo, J.10
-
62
-
-
0035710746
-
Analysis of relative gene expression data using real-time quantitative pcr and the 2 c (t) method
-
C (T) method. Methods 25:402–408.
-
(2001)
Methods
, vol.25
, pp. 402-408
-
-
Livak, K.J.1
Schmittgen, T.D.2
-
63
-
-
20344369562
-
A missense mutation in the previously undescribed gene tmhs underlies deafness in hurry-scurry (hscy) mice
-
Longo-Guess CM, Gagnon LH, Cook SA, Wu J, Zheng QY, Johnson KR (2005) A missense mutation in the previously undescribed gene Tmhs underlies deafness in hurry-scurry (hscy) mice. Proc Natl Acad Sci U S A 102:7894–7899.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7894-7899
-
-
Longo-Guess, C.M.1
Gagnon, L.H.2
Cook, S.A.3
Wu, J.4
Zheng, Q.Y.5
Johnson, K.R.6
-
64
-
-
79952256180
-
Noncanonical compensation of zygotic x transcription in early drosophila melanogaster development revealed through single-embryo rna-seq
-
Lott SE, Villalta JE, Schroth GP, Luo S, Tonkin LA, Eisen MB (2011) Noncanonical compensation of zygotic X transcription in early Drosophila melanogaster development revealed through single-embryo RNA-seq. PLoS Biol 9:e1000590.
-
(2011)
Plos Biol
, vol.9
-
-
Lott, S.E.1
Villalta, J.E.2
Schroth, G.P.3
Luo, S.4
Tonkin, L.A.5
Eisen, M.B.6
-
65
-
-
65449144302
-
Signaling pathways regulating zebrafish lateral line development
-
Ma EY, Raible DW (2009) Signaling pathways regulating zebrafish lateral line development. Curr Biol 19:R381–R386.
-
(2009)
Curr Biol
, vol.19
, pp. R381-R386
-
-
Ma, E.Y.1
Raible, D.W.2
-
66
-
-
39849089205
-
Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line
-
Ma EY, Rubel EW, Raible DW (2008) Notch signaling regulates the extent of hair cell regeneration in the zebrafish lateral line. J Neurosci 28:2261– 2273.
-
(2008)
J Neurosci
, vol.28
, pp. 2261-2273
-
-
Ma, E.Y.1
Rubel, E.W.2
Raible, D.W.3
-
67
-
-
79958117256
-
Meme-chip: Motif analysis of large dna datasets
-
Machanick P, Bailey TL (2011) MEME-ChIP: motif analysis of large DNA datasets. Bioinformatics 27:1696–1697.
-
(2011)
Bioinformatics
, vol.27
, pp. 1696-1697
-
-
Machanick, P.1
Bailey, T.L.2
-
68
-
-
25644435002
-
Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors
-
Machold R, Fishell G (2005) Math1 is expressed in temporally discrete pools of cerebellar rhombic-lip neural progenitors. Neuron 48:17–24.
-
(2005)
Neuron
, vol.48
, pp. 17-24
-
-
Machold, R.1
Fishell, G.2
-
69
-
-
77952362793
-
Muscarinic signaling in the cochlea: Presynaptic and postsynaptic effects on efferent feedback and afferent excitability
-
Maison SF, Liu XP, Vetter DE, Eatock RA, Nathanson NM, Wess J, Liberman MC (2010) Muscarinic signaling in the cochlea: presynaptic and postsynaptic effects on efferent feedback and afferent excitability. J Neurosci 30:6751–6762.
-
(2010)
J Neurosci
, vol.30
, pp. 6751-6762
-
-
Maison, S.F.1
Liu, X.P.2
Vetter, D.E.3
Eatock, R.A.4
Nathanson, N.M.5
Wess, J.6
Liberman, M.C.7
-
70
-
-
84929369309
-
Rbm24a and rbm24b are required for normal somitogenesis
-
Maragh S, Miller RA, Bessling SL, Wang G, Hook PW, McCallion AS (2014) Rbm24a and rbm24b are required for normal somitogenesis. PLoS One 9:e105460.
-
(2014)
Plos One
, vol.9
-
-
Maragh, S.1
Miller, R.A.2
Bessling, S.L.3
Wang, G.4
Hook, P.W.5
McCallion, A.S.6
-
71
-
-
82855172079
-
Regulation of pou4f3 gene expression in hair cells by 5 dna in mice
-
Masuda M, Dulon D, Pak K, Mullen LM, Li Y, Erkman L, Ryan AF (2011) Regulation of POU4F3 gene expression in hair cells by 5 DNA in mice. Neuroscience 197:48–64.
-
(2011)
Neuroscience
, vol.197
, pp. 48-64
-
-
Masuda, M.1
Dulon, D.2
Pak, K.3
Mullen, L.M.4
Li, Y.5
Erkman, L.6
Ryan, A.F.7
-
72
-
-
33745787321
-
The very large g-protein-coupled receptor vlgr1: A component of the ankle link complex required for the normal development of auditory hair bundles
-
McGee J, Goodyear RJ, McMillan DR, Stauffer EA, Holt JR, Locke KG, Birch DG, Legan PK, White PC, Walsh EJ, Richardson GP (2006) The very large G-protein-coupled receptor VLGR1: a component of the ankle link complex required for the normal development of auditory hair bundles. J Neurosci 26:6543–6553.
-
(2006)
J Neurosci
, vol.26
, pp. 6543-6553
-
-
McGee, J.1
Goodyear, R.J.2
McMillan, D.R.3
Stauffer, E.A.4
Holt, J.R.5
Locke, K.G.6
Birch, D.G.7
Legan, P.K.8
White, P.C.9
Walsh, E.J.10
Richardson, G.P.11
-
73
-
-
84857356790
-
Myosin iiib uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions
-
Merritt RC, Manor U, Salles FT, Grati M, Dose AC, Unrath WC, Quintero OA, Yengo CM, Kachar B (2012) Myosin IIIB uses an actin-binding motif in its espin-1 cargo to reach the tips of actin protrusions. Curr Biol 22:320–325.
-
(2012)
Curr Biol
, vol.22
, pp. 320-325
-
-
Merritt, R.C.1
Manor, U.2
Salles, F.T.3
Grati, M.4
Dose, A.C.5
Unrath, W.C.6
Quintero, O.A.7
Yengo, C.M.8
Kachar, B.9
-
74
-
-
0036667988
-
Mutation of the novel gene tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss dfnb6
-
Mitchem KL, Hibbard E, Beyer LA, Bosom K, Dootz GA, Dolan DF, Johnson KR, Raphael Y, Kohrman DC (2002) Mutation of the novel gene Tmie results in sensory cell defects in the inner ear of spinner, a mouse model of human hearing loss DFNB6. Hum Mol Genet 11:1887–1898.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1887-1898
-
-
Mitchem, K.L.1
Hibbard, E.2
Beyer, L.A.3
Bosom, K.4
Dootz, G.A.5
Dolan, D.F.6
Johnson, K.R.7
Raphael, Y.8
Kohrman, D.C.9
-
75
-
-
0032799390
-
Expression of delta1 and serrate1 (jagged1) in the mouse inner ear
-
Morrison A, Hodgetts C, Gossler A, Hrabé de Angelis M, Lewis J (1999) Expression of Delta1 and Serrate1 (Jagged1) in the mouse inner ear. Mech Dev 84:169–172.
-
(1999)
Mech Dev
, vol.84
, pp. 169-172
-
-
Morrison, A.1
Hodgetts, C.2
Gossler, A.3
Hrabé De Angelis, M.4
Lewis, J.5
-
76
-
-
50849144332
-
Cadherins and mechanotransduction by hair cells
-
Müller U (2008) Cadherins and mechanotransduction by hair cells. Curr Opin Cell Biol 20:557–566.
-
(2008)
Curr Opin Cell Biol
, vol.20
, pp. 557-566
-
-
Müller, U.1
-
77
-
-
84865516574
-
Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: Function, regulation, and context dependency
-
Mulvaney J, Dabdoub A (2012) Atoh1, an essential transcription factor in neurogenesis and intestinal and inner ear development: function, regulation, and context dependency. J Assoc Res Otolaryngol 13:281–293.
-
(2012)
J Assoc Res Otolaryngol
, vol.13
, pp. 281-293
-
-
Mulvaney, J.1
Dabdoub, A.2
-
78
-
-
33748335730
-
Kinetics of tamoxifenregulated cre activity in mice using a cartilage-specific creer t to assay temporal activity windows along the proximodistal limb skeleton
-
T to assay temporal activity windows along the proximodistal limb skeleton. Dev Dyn 235:2603–2612.
-
(2006)
Dev Dyn
, vol.235
, pp. 2603-2612
-
-
Nakamura, E.1
Nguyen, M.T.2
Mackem, S.3
-
79
-
-
84868110688
-
A mutation in the srrm4 gene causes alternative splicing defects and deafness in the bronx waltzer mouse
-
Nakano Y, Jahan I, Bonde G, Sun X, Hildebrand MS, Engelhardt JF, Smith RJ, Cornell RA, Fritzsch B, Bánfi B (2012) A mutation in the Srrm4 gene causes alternative splicing defects and deafness in the Bronx Waltzer mouse. PLoS Genet 8:e1002966.
-
(2012)
Plos Genet
, vol.8
-
-
Nakano, Y.1
Jahan, I.2
Bonde, G.3
Sun, X.4
Hildebrand, M.S.5
Engelhardt, J.F.6
Smith, R.J.7
Cornell, R.A.8
Fritzsch, B.9
Bánfi, B.10
-
80
-
-
69449105032
-
The ca2 channel subunit 2 regulates ca2 channel abundance and function in inner hair cells and is required for hearing
-
Neef J, Gehrt A, Bulankina AV, Meyer AC, Riedel D, Gregg RG, Strenzke N, Moser T (2009) The Ca2 channel subunit 2 regulates Ca2 channel abundance and function in inner hair cells and is required for hearing. J Neurosci 29:10730–10740.
-
(2009)
J Neurosci
, vol.29
, pp. 10730-10740
-
-
Neef, J.1
Gehrt, A.2
Bulankina, A.V.3
Meyer, A.C.4
Riedel, D.5
Gregg, R.G.6
Strenzke, N.7
Moser, T.8
-
81
-
-
33845900444
-
Distinct subdomain organization and molecular composition of a tight junction with adherens junction features
-
Nunes FD, Lopez LN, Lin HW, Davies C, Azevedo RB, Gow A, Kachar B (2006) Distinct subdomain organization and molecular composition of a tight junction with adherens junction features. J Cell Sci 119:4819–4827.
-
(2006)
J Cell Sci
, vol.119
, pp. 4819-4827
-
-
Nunes, F.D.1
Lopez, L.N.2
Lin, H.W.3
Davies, C.4
Azevedo, R.B.5
Gow, A.6
Kachar, B.7
-
82
-
-
76049130314
-
Mutations in grxcr1 are the basis for inner ear dysfunction in the pirouette mouse
-
Odeh H, Hunker KL, Belyantseva IA, Azaiez H, Avenarius MR, Zheng L, Peters LM, Gagnon LH, Hagiwara N, Skynner MJ, Brilliant MH, Allen ND, Riazuddin S, Johnson KR, Raphael Y, Najmabadi H, Friedman TB, Bartles JR, Smith RJ, Kohrman DC (2010) Mutations in Grxcr1 are the basis for inner ear dysfunction in the pirouette mouse. Am J Hum Genet 86:148–160.
-
(2010)
Am J Hum Genet
, vol.86
, pp. 148-160
-
-
Odeh, H.1
Hunker, K.L.2
Belyantseva, I.A.3
Azaiez, H.4
Avenarius, M.R.5
Zheng, L.6
Peters, L.M.7
Gagnon, L.H.8
Hagiwara, N.9
Skynner, M.J.10
Brilliant, M.H.11
Allen, N.D.12
Riazuddin, S.13
Johnson, K.R.14
Raphael, Y.15
Najmabadi, H.16
Friedman, T.B.17
Bartles, J.R.18
Smith, R.J.19
Kohrman, D.C.20
more..
-
83
-
-
0029558965
-
Cytoskeletal and calcium-binding proteins in the mammalian organ of corti: Cell type-specific proteins displaying longitudinal and radial gradients
-
Pack AK, Slepecky NB (1995) Cytoskeletal and calcium-binding proteins in the mammalian organ of Corti: cell type-specific proteins displaying longitudinal and radial gradients. Hear Res 91:119–135.
-
(1995)
Hear Res
, vol.91
, pp. 119-135
-
-
Pack, A.K.1
Slepecky, N.B.2
-
84
-
-
84855947953
-
A novel atoh1 “self-terminating” mouse model reveals the necessity of proper atoh1 level and duration for hair cell differentiation and viability
-
Pan N, Jahan I, Kersigo J, Duncan JS, Kopecky B, Fritzsch B (2012) A novel Atoh1 “self-terminating” mouse model reveals the necessity of proper Atoh1 level and duration for hair cell differentiation and viability. PLoS One 7:e30358.
-
(2012)
Plos One
, vol.7
-
-
Pan, N.1
Jahan, I.2
Kersigo, J.3
Duncan, J.S.4
Kopecky, B.5
Fritzsch, B.6
-
85
-
-
0036888465
-
Usherin expression is highly conserved in mouse and human tissues
-
Pearsall N, Bhattacharya G, Wisecarver J, Adams J, Cosgrove D, Kimberling W (2002) Usherin expression is highly conserved in mouse and human tissues. Hear Res 174:55–63.
-
(2002)
Hear Res
, vol.174
, pp. 55-63
-
-
Pearsall, N.1
Bhattacharya, G.2
Wisecarver, J.3
Adams, J.4
Cosgrove, D.5
Kimberling, W.6
-
86
-
-
33646883311
-
Basic helix-loop-helix gene hes6 delineates the sensory hair cell lineage in the inner ear
-
Qian D, Radde-Gallwitz K, Kelly M, Tyrberg B, Kim J, Gao WQ, Chen P (2006) Basic helix-loop-helix gene Hes6 delineates the sensory hair cell lineage in the inner ear. Dev Dyn 235:1689–1700.
-
(2006)
Dev Dyn
, vol.235
, pp. 1689-1700
-
-
Qian, D.1
Radde-Gallwitz, K.2
Kelly, M.3
Tyrberg, B.4
Kim, J.5
Gao, W.Q.6
Chen, P.7
-
87
-
-
46249099124
-
Novel mutations in lhx3 are associated with hypopituitarism and sensorineural hearing loss
-
Rajab A, Kelberman D, de Castro SC, Biebermann H, Shaikh H, Pearce K, Hall CM, Shaikh G, Gerrelli D, Grueters A, Krude H, Dattani MT (2008) Novel mutations in LHX3 are associated with hypopituitarism and sensorineural hearing loss. Hum Mol Genet 17:2150–2159.
-
(2008)
Hum Mol Genet
, vol.17
, pp. 2150-2159
-
-
Rajab, A.1
Kelberman, D.2
De Castro, S.C.3
Biebermann, H.4
Shaikh, H.5
Pearce, K.6
Hall, C.M.7
Shaikh, G.8
Gerrelli, D.9
Grueters, A.10
Krude, H.11
Dattani, M.T.12
-
88
-
-
70350784143
-
Math1 is essential for the development of hindbrain neurons critical for perinatal breathing
-
Rose MF, Ren J, Ahmad KA, Chao HT, Klisch TJ, Flora A, Greer JJ, Zoghbi HY (2009) Math1 is essential for the development of hindbrain neurons critical for perinatal breathing. Neuron 64:341–354.
-
(2009)
Neuron
, vol.64
, pp. 341-354
-
-
Rose, M.F.1
Ren, J.2
Ahmad, K.A.3
Chao, H.T.4
Klisch, T.J.5
Flora, A.6
Greer, J.J.7
Zoghbi, H.Y.8
-
89
-
-
79960530806
-
Analysis of gene expression profiles along the tonotopic map of mouse cochlea by cdna microarrays
-
Sato T, Doi K, Hibino H, Kubo T (2009) Analysis of gene expression profiles along the tonotopic map of mouse cochlea by cDNA microarrays. Acta Otolaryngol Suppl 562:12–17.
-
(2009)
Acta Otolaryngol Suppl
, vol.562
, pp. 12-17
-
-
Sato, T.1
Doi, K.2
Hibino, H.3
Kubo, T.4
-
90
-
-
34548755017
-
Gene expression profiling identifies hes6 as a transcriptional target of atoh1 in cochlear hair cells
-
Scheffer D, Sage C, Corey DP, Pingault V (2007a) Gene expression profiling identifies Hes6 as a transcriptional target of ATOH1 in cochlear hair cells. FEBS Lett 581:4651–4656.
-
(2007)
FEBS Lett
, vol.581
, pp. 4651-4656
-
-
Scheffer, D.1
Sage, C.2
Corey, D.P.3
Pingault, V.4
-
91
-
-
74449084340
-
The 1 subunit of nicotinic acetylcholine receptors in the inner ear: Transcriptional regulation by atoh1 and co-expression with the gamma subunit in hair cells
-
Scheffer D, Sage C, Plazas PV, Huang M, Wedemeyer C, Zhang DS, Chen ZY, Elgoyhen AB, Corey DP, Pingault V (2007b) The 1 subunit of nicotinic acetylcholine receptors in the inner ear: transcriptional regulation by ATOH1 and co-expression with the gamma subunit in hair cells. J Neurochem 103:2651–2664.
-
(2007)
J Neurochem
, vol.103
, pp. 2651-2664
-
-
Scheffer, D.1
Sage, C.2
Plazas, P.V.3
Huang, M.4
Wedemeyer, C.5
Zhang, D.S.6
Chen, Z.Y.7
Elgoyhen, A.B.8
Corey, D.P.9
Pingault, V.10
-
92
-
-
0034525302
-
Ribeye, a component of synaptic ribbons: A protein’s journey through evolution provides insight into synaptic ribbon function
-
Schmitz F, Königstorfer A, Südhof TC (2000) RIBEYE, a component of synaptic ribbons: a protein’s journey through evolution provides insight into synaptic ribbon function. Neuron 28:857–872.
-
(2000)
Neuron
, vol.28
, pp. 857-872
-
-
Schmitz, F.1
Königstorfer, A.2
Südhof, T.C.3
-
93
-
-
0036198940
-
Differential expression of the seven-pass transmembrane cadherin genes celsr1–3 and distribution of the celsr2 protein during mouse development
-
Shima Y, Copeland NG, Gilbert DJ, Jenkins NA, Chisaka O, Takeichi M, Uemura T (2002) Differential expression of the seven-pass transmembrane cadherin genes Celsr1–3 and distribution of the Celsr2 protein during mouse development. Dev Dyn 223:321–332.
-
(2002)
Dev Dyn
, vol.223
, pp. 321-332
-
-
Shima, Y.1
Copeland, N.G.2
Gilbert, D.J.3
Jenkins, N.A.4
Chisaka, O.5
Takeichi, M.6
Uemura, T.7
-
94
-
-
77954847853
-
The r109h variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of dba/2j mice
-
Shin JB, Longo-Guess CM, Gagnon LH, Saylor KW, Dumont RA, Spinelli KJ, Pagana JM, Wilmarth PA, David LL, Gillespie PG, Johnson KR (2010) The R109H variant of fascin-2, a developmentally regulated actin crosslinker in hair-cell stereocilia, underlies early-onset hearing loss of DBA/2J mice. J Neurosci 30:9683–9694.
-
(2010)
J Neurosci
, vol.30
, pp. 9683-9694
-
-
Shin, J.B.1
Longo-Guess, C.M.2
Gagnon, L.H.3
Saylor, K.W.4
Dumont, R.A.5
Spinelli, K.J.6
Pagana, J.M.7
Wilmarth, P.A.8
David, L.L.9
Gillespie, P.G.10
Johnson, K.R.11
-
95
-
-
84875890050
-
Molecular architecture of the chick vestibular hair bundle
-
Shin JB, Krey JF, Hassan A, Metlagel Z, Tauscher AN, Pagana JM, Sherman NE, Jeffery ED, Spinelli KJ, Zhao H, Wilmarth PA, Choi D, David LL, Auer M, Barr-Gillespie PG (2013) Molecular architecture of the chick vestibular hair bundle. Nat Neurosci 16:365–374.
-
(2013)
Nat Neurosci
, vol.16
, pp. 365-374
-
-
Shin, J.B.1
Krey, J.F.2
Hassan, A.3
Metlagel, Z.4
Tauscher, A.N.5
Pagana, J.M.6
Sherman, N.E.7
Jeffery, E.D.8
Spinelli, K.J.9
Zhao, H.10
Wilmarth, P.A.11
Choi, D.12
David, L.L.13
Auer, M.14
Barr-Gillespie, P.G.15
-
96
-
-
34249987090
-
Intestine-specific ablation of mouse atonal homolog 1 (math1) reveals a role in cellular homeostasis
-
Shroyer NF, Helmrath MA, Wang VY, Antalffy B, Henning SJ, Zoghbi HY (2007) Intestine-specific ablation of mouse atonal homolog 1 (Math1) reveals a role in cellular homeostasis. Gastroenterology 132:2478–2488.
-
(2007)
Gastroenterology
, vol.132
, pp. 2478-2488
-
-
Shroyer, N.F.1
Helmrath, M.A.2
Wang, V.Y.3
Antalffy, B.4
Henning, S.J.5
Zoghbi, H.Y.6
-
97
-
-
80053113119
-
Spatial and temporal expression patterns of nicotinic acetylcholine alpha9 and alpha10 subunits in the embryonic and early postnatal inner ear
-
Simmons DD, Morley BJ (2011) Spatial and temporal expression patterns of nicotinic acetylcholine alpha9 and alpha10 subunits in the embryonic and early postnatal inner ear. Neuroscience 194:326–336.
-
(2011)
Neuroscience
, vol.194
, pp. 326-336
-
-
Simmons, D.D.1
Morley, B.J.2
-
98
-
-
84855387944
-
Intrinsic regenerative potential of murine cochlear supporting cells
-
Sinkkonen ST, Chai R, Jan TA, Hartman BH, Laske RD, Gahlen F, Sinkkonen W, Cheng AG, Oshima K, Heller S (2011) Intrinsic regenerative potential of murine cochlear supporting cells. Sci Rep 1:26.
-
(2011)
Sci Rep
, vol.1
, pp. 26
-
-
Sinkkonen, S.T.1
Chai, R.2
Jan, T.A.3
Hartman, B.H.4
Laske, R.D.5
Gahlen, F.6
Sinkkonen, W.7
Cheng, A.G.8
Oshima, K.9
Heller, S.10
-
99
-
-
84863736333
-
Developmental gene expression profiling along the tonotopic axis of the mouse cochlea
-
Son EJ, Wu L, Yoon H, Kim S, Choi JY, Bok J (2012) Developmental gene expression profiling along the tonotopic axis of the mouse cochlea. PLoS One 7:e40735.
-
(2012)
Plos One
, vol.7
-
-
Son, E.J.1
Wu, L.2
Yoon, H.3
Kim, S.4
Choi, J.Y.5
Bok, J.6
-
100
-
-
3042856262
-
Cre reporter strains produced by targeted insertion of eyfp and ecfp into the rosa26 locus
-
Srinivas S, Watanabe T, Lin CS, William CM, Tanabe Y, Jessell TM, Costantini F (2001) Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus. BMC Dev Biol 1:4.
-
(2001)
BMC Dev Biol
, vol.1
, pp. 4
-
-
Srinivas, S.1
Watanabe, T.2
Lin, C.S.3
William, C.M.4
Tanabe, Y.5
Jessell, T.M.6
Costantini, F.7
-
101
-
-
0031963314
-
Detection of multiple gene products simultaneously by in situ hybridization and immunohistochemistry in whole mounts of avian embryos
-
Stern CD (1998) Detection of multiple gene products simultaneously by in situ hybridization and immunohistochemistry in whole mounts of avian embryos. Curr Top Dev Biol 36:223–243.
-
(1998)
Curr Top Dev Biol
, vol.36
, pp. 223-243
-
-
Stern, C.D.1
-
102
-
-
0037347254
-
Pcp4 is highly expressed in ectoderm and particularly in neuroectoderm derivatives during mouse embryogenesis
-
Thomas S, Thiery E, Aflalo R, Vayssettes C, Verney C, Berthuy I, Créau N (2003) PCP4 is highly expressed in ectoderm and particularly in neuroectoderm derivatives during mouse embryogenesis. Gene Expr Patterns 3:93–97.
-
(2003)
Gene Expr Patterns
, vol.3
, pp. 93-97
-
-
Thomas, S.1
Thiery, E.2
Aflalo, R.3
Vayssettes, C.4
Verney, C.5
Berthuy, I.6
Créau, N.7
-
103
-
-
80052155237
-
Nectins establish a checkerboard-like cellular pattern in the auditory epithelium
-
Togashi H, Kominami K, Waseda M, Komura H, Miyoshi J, Takeichi M, Takai Y (2011) Nectins establish a checkerboard-like cellular pattern in the auditory epithelium. Science 333:1144–1147.
-
(2011)
Science
, vol.333
, pp. 1144-1147
-
-
Togashi, H.1
Kominami, K.2
Waseda, M.3
Komura, H.4
Miyoshi, J.5
Takeichi, M.6
Takai, Y.7
-
104
-
-
65449136284
-
Tophat: Discovering splice junctions with rna-seq
-
Trapnell C, Pachter L, Salzberg SL (2009) TopHat: discovering splice junctions with RNA-Seq. Bioinformatics 25:1105–1111.
-
(2009)
Bioinformatics
, vol.25
, pp. 1105-1111
-
-
Trapnell, C.1
Pachter, L.2
Salzberg, S.L.3
-
105
-
-
20244389145
-
Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the dfnb16 locus
-
Verpy E, Masmoudi S, Zwaenepoel I, Leibovici M, Hutchin TP, Del Castillo I, Nouaille S, Blanchard S, Lainé S, Popot JL, Moreno F, Mueller RF, Petit C (2001) Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus. Nat Genet 29:345– 349.
-
(2001)
Nat Genet
, vol.29
, pp. 345-349
-
-
Verpy, E.1
Masmoudi, S.2
Zwaenepoel, I.3
Leibovici, M.4
Hutchin, T.P.5
Del Castillo, I.6
Nouaille, S.7
Blanchard, S.8
Lainé, S.9
Popot, J.L.10
Moreno, F.11
Mueller, R.F.12
Petit, C.13
-
107
-
-
0037232661
-
The zinc finger transcription factor gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival
-
Wallis D, Hamblen M, Zhou Y, Venken KJ, Schumacher A, Grimes HL, Zoghbi HY, Orkin SH, Bellen HJ (2003) The zinc finger transcription factor Gfi1, implicated in lymphomagenesis, is required for inner ear hair cell differentiation and survival. Development 130:221–232.
-
(2003)
Development
, vol.130
, pp. 221-232
-
-
Wallis, D.1
Hamblen, M.2
Zhou, Y.3
Venken, K.J.4
Schumacher, A.5
Grimes, H.L.6
Zoghbi, H.Y.7
Orkin, S.H.8
Bellen, H.J.9
-
108
-
-
0037188476
-
From flies’ eyes to our ears: Mutations in a human class iii myosin cause progressive nonsyndromic hearing loss dfnb30
-
Walsh T, Walsh V, Vreugde S, Hertzano R, Shahin H, Haika S, Lee MK, Kanaan M, King MC, Avraham KB (2002) From flies’ eyes to our ears: mutations in a human class III myosin cause progressive nonsyndromic hearing loss DFNB30. Proc Natl Acad Sci U S A 99:7518–7523.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7518-7523
-
-
Walsh, T.1
Walsh, V.2
Vreugde, S.3
Hertzano, R.4
Shahin, H.5
Haika, S.6
Lee, M.K.7
Kanaan, M.8
King, M.C.9
Avraham, K.B.10
-
109
-
-
0028144259
-
Expression of bdnf and nt-3 mrna in hair cells of the organ of corti: Quantitative analysis in developing rats
-
Wheeler EF, Bothwell M, Schecterson LC, von Bartheld CS (1994) Expression of BDNF and NT-3 mRNA in hair cells of the organ of Corti: quantitative analysis in developing rats. Hear Res 73:46–56.
-
(1994)
Hear Res
, vol.73
, pp. 46-56
-
-
Wheeler, E.F.1
Bothwell, M.2
Schecterson, L.C.3
Von Bartheld, C.S.4
-
110
-
-
13744263559
-
Math1 regulates development of the sensory epithelium in the mammalian cochlea
-
Woods C, Montcouquiol M, Kelley MW (2004) Math1 regulates development of the sensory epithelium in the mammalian cochlea. Nat Neurosci 7:1310–1318.
-
(2004)
Nat Neurosci
, vol.7
, pp. 1310-1318
-
-
Woods, C.1
Montcouquiol, M.2
Kelley, M.W.3
-
111
-
-
0031770385
-
Requirement for brn-3c in maturation and survival, but not in fate determination of inner ear hair cells
-
Xiang M, Gao WQ, Hasson T, Shin JJ (1998) Requirement for Brn-3c in maturation and survival, but not in fate determination of inner ear hair cells. Development 125:3935–3946.
-
(1998)
Development
, vol.125
, pp. 3935-3946
-
-
Xiang, M.1
Gao, W.Q.2
Hasson, T.3
Shin, J.J.4
-
112
-
-
84863297394
-
Functional features of trans-differentiated hair cells mediated by atoh1 reveals a primordial mechanism
-
Yang J, Bouvron S, Lv P, Chi F, Yamoah EN (2012a) Functional features of trans-differentiated hair cells mediated by Atoh1 reveals a primordial mechanism. J Neurosci 32:3712–3725.
-
(2012)
J Neurosci
, vol.32
, pp. 3712-3725
-
-
Yang, J.1
Bouvron, S.2
Lv, P.3
Chi, F.4
Yamoah, E.N.5
-
113
-
-
84866916331
-
Regeneration of stereocilia of hair cells by forced atoh1 expression in the adult mammalian cochlea
-
Yang SM, Chen W, Guo WW, Jia S, Sun JH, Liu HZ, Young WY, He DZ (2012b) Regeneration of stereocilia of hair cells by forced Atoh1 expression in the adult mammalian cochlea. PLoS One 7:e46355.
-
(2012)
Plos One
, vol.7
-
-
Yang, S.M.1
Chen, W.2
Guo, W.W.3
Jia, S.4
Sun, J.H.5
Liu, H.Z.6
Young, W.Y.7
He, D.Z.8
-
114
-
-
0027535610
-
Expression patterns of neurotrophin and their receptor mrnas in the rat inner ear
-
Ylikoski J, Pirvola U, Moshnyakov M, Palgi J, Arumäe U, Saarma M (1993) Expression patterns of neurotrophin and their receptor mRNAs in the rat inner ear. Hear Res 65:69–78.
-
(1993)
Hear Res
, vol.65
, pp. 69-78
-
-
Ylikoski, J.1
Pirvola, U.2
Moshnyakov, M.3
Palgi, J.4
Arumäe, U.5
Saarma, M.6
-
115
-
-
84864006635
-
Identification of genes concordantly expressed with atoh1 during inner ear development
-
Yoon H, Lee DJ, Kim MH, Bok J (2011) Identification of genes concordantly expressed with Atoh1 during inner ear development. Anat Cell Biol 44: 69–78.
-
(2011)
Anat Cell Biol
, vol.44
, pp. 69-78
-
-
Yoon, H.1
Lee, D.J.2
Kim, M.H.3
Bok, J.4
-
116
-
-
78751482241
-
Cilia-driven fluid flow as an epigenetic cue for otolith biomineralization on sensory hair cells of the inner ear
-
Yu X, Lau D, Ng CP, Roy S (2011) Cilia-driven fluid flow as an epigenetic cue for otolith biomineralization on sensory hair cells of the inner ear. Development 138:487–494.
-
(2011)
Development
, vol.138
, pp. 487-494
-
-
Yu, X.1
Lau, D.2
Ng, C.P.3
Roy, S.4
-
117
-
-
53849146020
-
Model-based analysis of chip-seq (macs)
-
Zhang Y, Liu T, Meyer CA, Eeckhoute J, Johnson DS, Bernstein BE, Nusbaum C, Myers RM, Brown M, Li W, Liu XS (2008) Model-based analysis of ChIP-Seq (MACS). Genome Biol 9:R137.
-
(2008)
Genome Biol
, vol.9
, pp. R137
-
-
Zhang, Y.1
Liu, T.2
Meyer, C.A.3
Eeckhoute, J.4
Johnson, D.S.5
Bernstein, B.E.6
Nusbaum, C.7
Myers, R.M.8
Brown, M.9
Li, W.10
Liu, X.S.11
-
118
-
-
0034127584
-
Overexpression of math1 induces robust production of extra hair cells in postnatal rat inner ears
-
Zheng JL, Gao WQ (2000) Overexpression of Math1 induces robust production of extra hair cells in postnatal rat inner ears. Nat Neurosci 3:580– 586.
-
(2000)
Nat Neurosci
, vol.3
, pp. 580-586
-
-
Zheng, J.L.1
Gao, W.Q.2
|