Metabolic profile of 2-(2-hydroxypropanamido) benzoic acid in rats by ultra high performance liquid chromatography combined with Fourier transform ion cyclotron resonance mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 993-994, Issue , 2015, Pages 60-68

  Guan, Jiao ^a,b   Zhang, Qili ^a   Rong, Rong ^a   Han, Fei ^a   Zhu, Heyun ^a,b   Zhao, Yunli ^a   Song, Aihua ^a   Yu, Zhiguo ^a  

^a SHENYANG PHARMACEUTICAL UNIVERSITY   (China)

^b JILIN MEDICAL COLLEGE   (China)

Author keywords

2 (2 hydroxypropanamido) benzoic acid; Identification; Metabolism; Rat; UHPLC FT ICR MS

Indexed keywords

AMINO ACIDS; CARBOXYLATION; CYCLOTRONS; DRUG PRODUCTS; ELECTRON CYCLOTRON RESONANCE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IDENTIFICATION (CONTROL SYSTEMS); MASS SPECTROMETRY; METABOLISM; METABOLITES; RATING; RATS;

ANTI-INFLAMMATORY DRUGS; FOURIER TRANSFORM ION CYCLOTRON RESONANCE MASS SPECTROMETRY; FT-ICR MS; INTRAGASTRIC ADMINISTRATION; MECHANISM OF ACTION; METABOLIC PATHWAYS; METABOLIC PROFILES; ULTRA-HIGH PERFORMANCE LIQUID CHROMATOGRAPHIES;

BENZOIC ACID;

2 (2 HYDROXYPROPANAMIDO) BENZOIC ACID; ACETIC ACID DERIVATIVE; BENZOIC ACID DERIVATIVE; DRUG METABOLITE; GLYCINE; UNCLASSIFIED DRUG; 2-(2-HYDROXYPROPANAMIDO)BENZOIC ACID;

ANIMAL EXPERIMENT; ARTICLE; BILE; BLOOD SAMPLING; CONJUGATION; CONTROLLED STUDY; DECARBOXYLATION; DEHYDROGENATION; DRUG METABOLISM; FECES ANALYSIS; FEMALE; GLUCURONIDATION; GLYCINE CONJUGATION; HYDROXYLATION; ION CYCLOTRON RESONANCE MASS SPECTROMETRY; MALE; N ACETYL CONJUGATION; NONHUMAN; PRIORITY JOURNAL; RAT; SINGLE DRUG DOSE; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY; URINALYSIS; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; EVALUATION STUDY; FECES; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PROCEDURES; SPRAGUE DAWLEY RAT;

RATTUS;

ANIMALS; BENZOATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FECES; FEMALE; MALE; MASS SPECTROMETRY; MOLECULAR STRUCTURE; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84929376908     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2015.04.039     Document Type: Article

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