Sustained interleukin-1β exposure modulates multiple steps in glucocorticoid receptor signaling, promoting split-resistance to the transactivation of prominent anti-inflammatory genes by glucocorticoids

Mediators of Inflammation

Volumn 2015, Issue , 2015, Pages

  Escoll, Pedro ^a,b   Ranz, Ismael ^a,c   Muñoz Antón, Norman ^a   Van Den Rym, Ana ^a   Alvarez Mon, Melchor ^a   Martínez Alonso, Carlos ^d   Sanz, Eva ^a   De La Hera, Antonio ^a  

^a UNIVERSITY OF ALCALÁ   (Spain)

^b INSTITUT PASTEUR   (France)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d CENTRO NACIONAL DE BIOTECNOLOGÍA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE RICH PROTEIN 61; GILZ PROTEIN; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR; INTERFERON CONSENSUS SEQUENCE BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; PROTEIN; UNCLASSIFIED DRUG; FK 506 BINDING PROTEIN; IGFBP1 PROTEIN, HUMAN; INTERFERON REGULATORY FACTOR; SOMATOMEDIN BINDING PROTEIN 1; TACROLIMUS BINDING PROTEIN 5; TRISTETRAPROLIN; ZFP36 PROTEIN, HUMAN;

ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; CYTOPLASM; GENE EXPRESSION; GENE FUNCTION; GENE SILENCING; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TARGET CELL; TRANSACTIVATION; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GENETICS; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; FLUORESCENT ANTIBODY TECHNIQUE; GLUCOCORTICOIDS; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 1; INTERFERON REGULATORY FACTORS; INTERLEUKIN-1BETA; PHOSPHORYLATION; RECEPTORS, GLUCOCORTICOID; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; TACROLIMUS BINDING PROTEINS; TRISTETRAPROLIN;

EID: 84929358829     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2015/347965     Document Type: Article

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