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Volumn 50, Issue 1, 2012, Pages

The emerging role of the mitochondrial-derived peptide humanin in stress resistance

Author keywords

Apoptosis; Cardiovascular; Diabetes (all); Signal transduction

Indexed keywords

ACETYLCHOLINE; AMYLOID BETA PROTEIN; HUMANIN; POLYGLUTAMINE; PRESENILIN 1; PRESENILIN 2; REACTIVE OXYGEN METABOLITE;

EID: 84873390153     PISSN: 09525041     EISSN: 14796813     Source Type: Journal    
DOI: 10.1530/JME-12-0203     Document Type: Review
Times cited : (162)

References (52)
  • 3
    • 13944278132 scopus 로고    scopus 로고
    • Mitochondria, oxidants, and aging
    • (doi:10.1016/j.cell.2005.02.001)
    • Balaban R, Nemoto S & Finkel T 2005 Mitochondria, oxidants, and aging. Cell 120 483-495. (doi:10.1016/j.cell.2005.02.001)
    • (2005) Cell , vol.120 , pp. 483-495
    • Balaban, R.1    Nemoto, S.2    Finkel, T.3
  • 4
    • 70249151354 scopus 로고    scopus 로고
    • Evidence for potential functionality of nuclearly-encoded humanin isoforms
    • (doi:10.1016/j.ygeno.2009.05.006)
    • Bodzioch M, Lapicka-Bodzioch K, Zapala B, Kamysz W, Kiec-Wilk B & Dembinska-Kiec A 2009 Evidence for potential functionality of nuclearly-encoded humanin isoforms. Genomics 94 247-256. (doi:10.1016/j.ygeno.2009.05.006)
    • (2009) Genomics , vol.94 , pp. 247-256
    • Bodzioch, M.1    Lapicka-Bodzioch, K.2    Zapala, B.3    Kamysz, W.4    Kiec-Wilk, B.5    Dembinska-Kiec, A.6
  • 5
    • 80054953358 scopus 로고    scopus 로고
    • After half a century mitochondrial calcium in- and efflux machineries reveal themselves
    • (doi:10.1038/emboj.2011.337)
    • Drago I, Pizzo P & Pozzan T 2011 After half a century mitochondrial calcium in- and efflux machineries reveal themselves. EMBO Journal 30 4119-4125. (doi:10.1038/emboj.2011.337)
    • (2011) EMBO Journal , vol.30 , pp. 4119-4125
    • Drago, I.1    Pizzo, P.2    Pozzan, T.3
  • 6
    • 78650944949 scopus 로고    scopus 로고
    • The cell-non-autonomous nature of electron transport chain-mediated longevity
    • (doi:10.1016/j.cell.2010.12.016)
    • Durieux J, Wolff S & Dillin A 2011 The cell-non-autonomous nature of electron transport chain-mediated longevity. Cell 144 79-91. (doi:10.1016/j.cell.2010.12.016)
    • (2011) Cell , vol.144 , pp. 79-91
    • Durieux, J.1    Wolff, S.2    Dillin, A.3
  • 7
    • 0038485614 scopus 로고    scopus 로고
    • Humanin peptide suppresses apoptosis by interfering with Bax activation
    • (doi:10.1038/nature01627)
    • Guo B, Zhai D, Cabezas E, Welsh K, Nouraini S, Satterthwait AC & Reed JC 2003 Humanin peptide suppresses apoptosis by interfering with Bax activation. Nature 423 456-461. (doi:10.1038/nature01627)
    • (2003) Nature , vol.423 , pp. 456-461
    • Guo, B.1    Zhai, D.2    Cabezas, E.3    Welsh, K.4    Nouraini, S.5    Satterthwait, A.C.6    Reed, J.C.7
  • 9
  • 10
    • 4243333514 scopus 로고    scopus 로고
    • A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Ab
    • (doi:10.1073/pnas.101133498)
    • Hashimoto Y, Niikura T, Tajima H, Yasukawa T, Sudo H, Ito Y, Kita Y, Kawasumi M, Kouyama K, Doyu M et al. 2001b A rescue factor abolishing neuronal cell death by a wide spectrum of familial Alzheimer's disease genes and Ab. PNAS 98 6336-6341. (doi:10.1073/pnas.101133498)
    • (2001) PNAS , vol.98 , pp. 6336-6341
    • Hashimoto, Y.1    Niikura, T.2    Tajima, H.3    Yasukawa, T.4    Sudo, H.5    Ito, Y.6    Kita, Y.7    Kawasumi, M.8    Kouyama, K.9    Doyu, M.10
  • 11
    • 26444463390 scopus 로고    scopus 로고
    • Involvement of tyrosine kinases and STAT3 in humanin-mediated neuroprotection
    • (doi:10.1016/j.lfs.2005.03.031)
    • Hashimoto YY, Suzuki HH, Aiso S, Niikura T, Nishimoto I & Matsuoka MM 2005 Involvement of tyrosine kinases and STAT3 in humanin-mediated neuroprotection. Life Sciences 77 3092-3104. (doi:10.1016/j.lfs.2005.03.031)
    • (2005) Life Sciences , vol.77 , pp. 3092-3104
    • Hashimoto, Y.Y.1    Suzuki, H.H.2    Aiso, S.3    Niikura, T.4    Nishimoto, I.5    Matsuoka, M.M.6
  • 12
    • 67449124590 scopus 로고    scopus 로고
    • Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor a/WSX-1/gp130
    • (doi:10.1091/mbc.E09-02-0168)
    • Hashimoto Y, Kurita M & Aiso S 2009 Humanin inhibits neuronal cell death by interacting with a cytokine receptor complex or complexes involving CNTF receptor a/WSX-1/gp130. Molecular Biology of the Cell 20 2864-2873. (doi:10.1091/mbc.E09-02-0168)
    • (2009) Molecular Biology of the Cell , vol.20 , pp. 2864-2873
    • Hashimoto, Y.1    Kurita, M.2    Aiso, S.3
  • 13
    • 76849100919 scopus 로고    scopus 로고
    • The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans
    • (doi:10.1016/j.molcel.2010.01.015)
    • Haynes CM, Yang Y, Blais SP, Neubert TA & Ron D 2010 The matrix peptide exporter HAF-1 signals a mitochondrial UPR by activating the transcription factor ZC376.7 in C. elegans. Molecular Cell 37 529-540. (doi:10.1016/j.molcel.2010.01.015)
    • (2010) Molecular Cell , vol.37 , pp. 529-540
    • Haynes, C.M.1    Yang, Y.2    Blais, S.P.3    Neubert, T.A.4    Ron, D.5
  • 14
    • 0242268394 scopus 로고    scopus 로고
    • Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis
    • (doi:10.1073/pnas.2135111100)
    • Ikonen M, Liu B, Hashimoto Y, Ma L, Lee K-W, Niikura T, Nishimoto I & Cohen P 2003 Interaction between the Alzheimer's survival peptide humanin and insulin-like growth factor-binding protein 3 regulates cell survival and apoptosis. PNAS 100 13042-13047. (doi:10.1073/pnas.2135111100)
    • (2003) PNAS , vol.100 , pp. 13042-13047
    • Ikonen, M.1    Liu, B.2    Hashimoto, Y.3    Ma, L.4    Lee, K.-W.5    Niikura, T.6    Nishimoto, I.7    Cohen, P.8
  • 15
    • 79952708318 scopus 로고    scopus 로고
    • Caspase-8 and bid: Caught in the act between death receptors and mitochondria
    • (doi:10.1016/j.bbamcr.2011.01.026)
    • Kantari C & Walczak H 2011 Caspase-8 and bid: caught in the act between death receptors and mitochondria. Biochimica et Biophysica Acta 1813 558-563. (doi:10.1016/j.bbamcr.2011.01.026)
    • (2011) Biochimica Et Biophysica Acta , vol.1813 , pp. 558-563
    • Kantari, C.1    Walczak, H.2
  • 16
    • 0037035593 scopus 로고    scopus 로고
    • Humanin inhibits cell death of serum-deprived PC12h cells
    • (doi:10.1097/00001756-200205070-00034)
    • Kariya S, Takahashi N, Ooba N, Kawahara M, Nakayama H & Ueno S 2002 Humanin inhibits cell death of serum-deprived PC12h cells. Neuroreport 13 903-907. (doi:10.1097/00001756-200205070-00034)
    • (2002) Neuroreport , vol.13 , pp. 903-907
    • Kariya, S.1    Takahashi, N.2    Ooba, N.3    Kawahara, M.4    Nakayama, H.5    Ueno, S.6
  • 17
    • 0344034355 scopus 로고    scopus 로고
    • Humanin improves impaired metabolic activity and prolongs survival of serum-deprived human lymphocytes
    • (doi:10.1023/A:1027372519726)
    • Kariya S, Takahashi N & Hirano M 2003 Humanin improves impaired metabolic activity and prolongs survival of serum-deprived human lymphocytes. Molecular and Cellular Biochemistry 254 83-89. (doi:10.1023/A:1027372519726)
    • (2003) Molecular and Cellular Biochemistry , vol.254 , pp. 83-89
    • Kariya, S.1    Takahashi, N.2    Hirano, M.3
  • 18
    • 22244459510 scopus 로고    scopus 로고
    • Humanin attenuates apoptosis induced by DRPLA proteins with expanded polyglutamine stretches
    • (doi:10.1385/JMN:25:2:165)
    • Kariya S, Hirano M, Nagai Y, Furiya Y, Fujikake N, Toda T & Ueno S 2005 Humanin attenuates apoptosis induced by DRPLA proteins with expanded polyglutamine stretches. Journal of Molecular Neuroscience 25 165-169. (doi:10.1385/JMN:25:2:165)
    • (2005) Journal of Molecular Neuroscience , vol.25 , pp. 165-169
    • Kariya, S.1    Hirano, M.2    Nagai, Y.3    Furiya, Y.4    Fujikake, N.5    Toda, T.6    Ueno, S.7
  • 20
    • 6944252056 scopus 로고    scopus 로고
    • Effect of humanin analogues on experimentally induced impairment of spatial memory in rats
    • (doi:10.1002/psc.569)
    • Krejcova G, Patocka J & Slaninova J 2004 Effect of humanin analogues on experimentally induced impairment of spatial memory in rats. Journal of Peptide Science 10 636-639. (doi:10.1002/psc.569)
    • (2004) Journal of Peptide Science , vol.10 , pp. 636-639
    • Krejcova, G.1    Patocka, J.2    Slaninova, J.3
  • 21
    • 0036839229 scopus 로고    scopus 로고
    • Formyl-peptide receptors revisited
    • (doi:10.1016/S1471-4906(02)02316-5)
    • Le Y, Murphy PM & Wang JM 2002 Formyl-peptide receptors revisited. Trends in Immunology 23 541-548. (doi:10.1016/S1471-4906(02)02316-5)
    • (2002) Trends In Immunology , vol.23 , pp. 541-548
    • Le, Y.1    Murphy, P.M.2    Wang, J.M.3
  • 23
    • 84861230054 scopus 로고    scopus 로고
    • Interaction structure of the complex between neuroprotective factor humanin and Alzheimer's b-amyloid peptide revealed by affinity mass spectrometry and molecular modeling
    • (doi:10.1002/psc.2404)
    • Maftei M, Tian X, Manea M, Exner TE, Schwanzar D, Arnimvon CAF & Przybylski M 2012 Interaction structure of the complex between neuroprotective factor humanin and Alzheimer's b-amyloid peptide revealed by affinity mass spectrometry and molecular modeling. Journal of Peptide Science 18 373-382. (doi:10.1002/psc.2404)
    • (2012) Journal of Peptide Science , vol.18 , pp. 373-382
    • Maftei, M.1    Tian, X.2    Manea, M.3    Exner, T.E.4    Schwanzar, D.5    Arnimvon, C.A.F.6    Przybylski, M.7
  • 24
    • 0035678839 scopus 로고    scopus 로고
    • [Gly14]-humanin improved the learning and memory impairment induced by scopolamine in vivo
    • (doi:10.1038/sj.bjp.0704429)
    • Mamiya T 2001 [Gly14]-humanin improved the learning and memory impairment induced by scopolamine in vivo. British Journal of Pharmacology 134 1597-1599. (doi:10.1038/sj.bjp.0704429)
    • (2001) British Journal of Pharmacology , vol.134 , pp. 1597-1599
    • Mamiya, T.1
  • 25
    • 84859704215 scopus 로고    scopus 로고
    • An AD-related neuroprotector rescues transformed rat retinal ganglion cells from CoCl(2)-induced apoptosis
    • (doi:10.1007/s12031-011-9701-5)
    • Men J, Zhang X, Yang Y & Gao D 2012 An AD-related neuroprotector rescues transformed rat retinal ganglion cells from CoCl(2)-induced apoptosis. Journal of Molecular Neuroscience 47 144-149. (doi:10.1007/s12031-011-9701-5)
    • (2012) Journal of Molecular Neuroscience , vol.47 , pp. 144-149
    • Men, J.1    Zhang, X.2    Yang, Y.3    Gao, D.4
  • 27
    • 56349147722 scopus 로고    scopus 로고
    • S14G-Humanin ameliorates Ab25-35-induced behavioral deficits by reducing neuroinflammatory responses and apoptosis in mice
    • (doi:10.1016/j.npep.2008.08.004)
    • Miao J, Zhang W & Li Z 2008 S14G-Humanin ameliorates Ab25-35-induced behavioral deficits by reducing neuroinflammatory responses and apoptosis in mice. Neuropeptides 42 557-567. (doi:10.1016/j.npep.2008.08.004)
    • (2008) Neuropeptides , vol.42 , pp. 557-567
    • Miao, J.1    Zhang, W.2    Li, Z.3
  • 30
    • 0031913875 scopus 로고    scopus 로고
    • Detection, localization, and sequence analyses of mitochondrial regulatory region RNAs in several mammalian species
    • (doi:10.1093/oxfordjournals.jbchem.a021950)
    • Nakamichi N, Rhoads DD, Hayashi JI, Kagawa Y & Matsumura T 1998 Detection, localization, and sequence analyses of mitochondrial regulatory region RNAs in several mammalian species. Journal of Biochemistry 123 392-398. (doi:10.1093/oxfordjournals.jbchem.a021950)
    • (1998) Journal of Biochemistry , vol.123 , pp. 392-398
    • Nakamichi, N.1    Rhoads, D.D.2    Hayashi, J.I.3    Kagawa, Y.4    Matsumura, T.5
  • 32
    • 79251577369 scopus 로고    scopus 로고
    • A humanin derivative reduces amyloid b accumulation and ameliorates memory deficit in triple transgenic mice
    • (doi:10.1371/journal.pone.0016259)
    • Niikura T, Sidahmed E, Hirata-Fukae C, Aisen PS & Matsuoka Y 2011 A humanin derivative reduces amyloid b accumulation and ameliorates memory deficit in triple transgenic mice. PLoS ONE 6 e16259. (doi:10.1371/journal.pone.0016259)
    • (2011) PLoS ONE , vol.6
    • Niikura, T.1    Sidahmed, E.2    Hirata-Fukae, C.3    Aisen, P.S.4    Matsuoka, Y.5
  • 33
    • 80054969930 scopus 로고    scopus 로고
    • Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice
    • (doi:10.1016/j.atherosclerosis.2011.06.038)
    • Oh YK, Bachar AR, Zacharias DG, Kim SG, Wan J, Cobb LJ, Lerman LO, Cohen P & Lerman A 2011 Humanin preserves endothelial function and prevents atherosclerotic plaque progression in hypercholesterolemic ApoE deficient mice. Atherosclerosis 219 65-73. (doi:10.1016/j.atherosclerosis.2011.06.038)
    • (2011) Atherosclerosis , vol.219 , pp. 65-73
    • Oh, Y.K.1    Bachar, A.R.2    Zacharias, D.G.3    Kim, S.G.4    Wan, J.5    Cobb, L.J.6    Lerman, L.O.7    Cohen, P.8    Lerman, A.9
  • 35
    • 77952548782 scopus 로고    scopus 로고
    • How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis)
    • (doi:10.1016/j.exger.2010.03.014)
    • Ristow M & Zarse K 2010 How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis). Experimental Gerontology 45 410-418. (doi:10.1016/j.exger.2010.03.014)
    • (2010) Experimental Gerontology , vol.45 , pp. 410-418
    • Ristow, M.1    Zarse, K.2
  • 38
    • 0004071012 scopus 로고
    • edn 5, Malden, MA: Blackwell Publishing Ltd
    • Salway JG 1994 Metabolism at a Glance. edn 5, pp 10, Malden, MA: Blackwell Publishing Ltd.
    • (1994) Metabolism At a Glance , pp. 10
    • Salway, J.G.1
  • 41
    • 78049430399 scopus 로고    scopus 로고
    • Polyglutamine diseases: Where does toxicity come from? what is toxicity? where are we going?
    • (doi:10.1093/jmcb/mjq005)
    • Takahashi T, Katada S & Onodera O 2010 Polyglutamine diseases: where does toxicity come from? what is toxicity? where are we going? Journal of Molecular Cell Biology 2 180-191. (doi:10.1093/jmcb/mjq005)
    • (2010) Journal of Molecular Cell Biology , vol.2 , pp. 180-191
    • Takahashi, T.1    Katada, S.2    Onodera, O.3
  • 42
    • 0035890085 scopus 로고    scopus 로고
    • The expanding role of mitochondria in apoptosis
    • Wang X 2001 The expanding role of mitochondria in apoptosis. Genes and Development 15 2922-2933.
    • (2001) Genes and Development , vol.15 , pp. 2922-2933
    • Wang, X.1
  • 43
  • 44
    • 48949104380 scopus 로고    scopus 로고
    • Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway
    • (doi:10.1016/j.brainres.2008.06.018)
    • Xu X, Chua C, Gao J, Chua K & Wang H 2008 Neuroprotective effect of humanin on cerebral ischemia/reperfusion injury is mediated by a PI3K/Akt pathway. Brain Research 1227 12-18. (doi:10.1016/j.brainres.2008.06.018)
    • (2008) Brain Research , vol.1227 , pp. 12-18
    • Xu, X.1    Chua, C.2    Gao, J.3    Chua, K.4    Wang, H.5
  • 45
    • 0013056674 scopus 로고    scopus 로고
    • Identification of essential amino acids in humanin, a neuroprotective factor against Alzheimer's disease-relevant insults
    • (doi:10.1016/S0196-9781(03)00106-2)
    • Yamagishi Y, Hashimoto Y, Niikura T & Nishimoto I 2003 Identification of essential amino acids in humanin, a neuroprotective factor against Alzheimer's disease-relevant insults. Peptides 24 585-595. (doi:10.1016/S0196-9781(03)00106-2)
    • (2003) Peptides , vol.24 , pp. 585-595
    • Yamagishi, Y.1    Hashimoto, Y.2    Niikura, T.3    Nishimoto, I.4
  • 46
    • 40949084677 scopus 로고    scopus 로고
    • Protective effects of tetramethylpyrazine on rat retinal cell cultures
    • (doi:10.1016/j.neuint.2007.12.008)
    • Yang Z, Zhang Q, Ge J & Tan Z 2008 Protective effects of tetramethylpyrazine on rat retinal cell cultures. Neurochemistry International 52 1176-1187. (doi:10.1016/j.neuint.2007.12.008)
    • (2008) Neurochemistry International , vol.52 , pp. 1176-1187
    • Yang, Z.1    Zhang, Q.2    Ge, J.3    Tan, Z.4
  • 47
    • 2442705358 scopus 로고    scopus 로고
    • Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor
    • Ying G, Iribarren P, Zhou Y, Gong W, Zhang N, Yu Z-X, Le Y, Cui Y & Wang JM 2004 Humanin, a newly identified neuroprotective factor, uses the G protein-coupled formylpeptide receptor-like-1 as a functional receptor. Journal of Immunology 172 7078-7085.
    • (2004) Journal of Immunology , vol.172 , pp. 7078-7085
    • Ying, G.1    Iribarren, P.2    Zhou, Y.3    Gong, W.4    Zhang, N.5    Yu, Z.-X.6    Le, Y.7    Cui, Y.8    Wang, J.M.9
  • 49
    • 18144399957 scopus 로고    scopus 로고
    • Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak
    • (doi:10.1074/jbc.M411902200)
    • Zhai D, Luciano F, Zhu X, Guo B, Satterthwait AC & Reed JC 2005 Humanin binds and nullifies Bid activity by blocking its activation of Bax and Bak. Journal of Biological Chemistry 280 15815-15824. (doi:10.1074/jbc.M411902200)
    • (2005) Journal of Biological Chemistry , vol.280 , pp. 15815-15824
    • Zhai, D.1    Luciano, F.2    Zhu, X.3    Guo, B.4    Satterthwait, A.C.5    Reed, J.C.6
  • 50
    • 67349199177 scopus 로고    scopus 로고
    • Protective effect of S14G-humanin against β-amyloid induced LTP inhibition in mouse hippocampal slices
    • (doi:10.1016/j.peptides.2009.02.017)
    • Zhang W, Miao J, Hao J, Li Z, Xu J, Liu R, Cao F, Wang R, Chen J & Li Z 2009 Protective effect of S14G-humanin against β-amyloid induced LTP inhibition in mouse hippocampal slices. Peptides 30 1197-1202. (doi:10.1016/j.peptides.2009.02.017)
    • (2009) Peptides , vol.30 , pp. 1197-1202
    • Zhang, W.1    Miao, J.2    Hao, J.3    Li, Z.4    Xu, J.5    Liu, R.6    Cao, F.7    Wang, R.8    Chen, J.9    Li, Z.10
  • 51
    • 80054098429 scopus 로고    scopus 로고
    • S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice
    • (doi:10.1016/j.pbb.2011.09.012)
    • Zhang W, Zhang W, Li Z, Hao J, Zhang Z, Liu L, Mao N, Miao J & Zhang L 2012 S14G-humanin improves cognitive deficits and reduces amyloid pathology in the middle-aged APPswe/PS1dE9 mice. Pharmacology, Biochemistry, and Behavior 100 361-369. (doi:10.1016/j.pbb.2011.09.012)
    • (2012) Pharmacology, Biochemistry, and Behavior , vol.100 , pp. 361-369
    • Zhang, W.1    Zhang, W.2    Li, Z.3    Hao, J.4    Zhang, Z.5    Liu, L.6    Mao, N.7    Miao, J.8    Zhang, L.9
  • 52
    • 0043207393 scopus 로고    scopus 로고
    • Humanin peptides block calcium influx of rat hippocampal neurons by altering fibrogenesis of Ab(1-40)
    • (doi:10.1016/S0196-9781(03)00131-1)
    • Zou P, Ding Y, Sha Y, Hu B & Nie S 2003 Humanin peptides block calcium influx of rat hippocampal neurons by altering fibrogenesis of Ab(1-40). Peptides 24 679-685. (doi:10.1016/S0196-9781(03)00131-1)
    • (2003) Peptides , vol.24 , pp. 679-685
    • Zou, P.1    Ding, Y.2    Sha, Y.3    Hu, B.4    Nie, S.5


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