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Volumn 35, Issue 16, 2015, Pages 6429-6443

Protein interacting with C-kinase 1 deficiency impairs glutathione synthesis and increases oxidative stress via reduction of surface excitatory amino acid carrier 1

Author keywords

EAAC1; Glutathione; Oxidant; Oxidative stress; PICK1; Rab11

Indexed keywords

3 NITROTYROSINE; CREATINE KINASE BB; CYSTEINE; EXCITATORY AMINO ACID TRANSPORTER 3; GLUTATHIONE; LENTIVIRUS VECTOR; RAB11 PROTEIN; REACTIVE OXYGEN METABOLITE; CARRIER PROTEIN; NUCLEAR PROTEIN; PRKCABP PROTEIN, MOUSE; RAB PROTEIN; SLC1A1 PROTEIN, MOUSE;

EID: 84929347147     PISSN: 02706474     EISSN: 15292401     Source Type: Journal    
DOI: 10.1523/JNEUROSCI.3966-14.2015     Document Type: Article
Times cited : (16)

References (73)
  • 1
    • 79951543816 scopus 로고    scopus 로고
    • PICK1 loss of function occludes homeostatic synaptic scaling
    • CrossRef Medline
    • Anggono V, Clem RL, Huganir RL (2011) PICK1 loss of function occludes homeostatic synaptic scaling. J Neurosci 31:2188-2196. CrossRef Medline
    • (2011) J Neurosci , vol.31 , pp. 2188-2196
    • Anggono, V.1    Clem, R.L.2    Huganir, R.L.3
  • 2
    • 29444459269 scopus 로고    scopus 로고
    • Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse
    • CrossRef Medline
    • Aoyama K, Suh SW, Hamby AM, Liu J, Chan WY, Chen Y, Swanson RA (2005) Neuronal glutathione deficiency and age-dependent neurodegeneration in the EAAC1 deficient mouse. Nat Neurosci 9:119-126. CrossRef Medline
    • (2005) Nat Neurosci , vol.9 , pp. 119-126
    • Aoyama, K.1    Suh, S.W.2    Hamby, A.M.3    Liu, J.4    Chan, W.Y.5    Chen, Y.6    Swanson, R.A.7
  • 3
    • 37748999265 scopus 로고    scopus 로고
    • Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction
    • CrossRef Medline
    • Aoyama K, Matsumura N, Watabe M, Nakaki T (2008) Oxidative stress on EAAC1 is involved in MPTP-induced glutathione depletion and motor dysfunction. Eur J Neurosci 27:20-30. CrossRef Medline
    • (2008) Eur J Neurosci , vol.27 , pp. 20-30
    • Aoyama, K.1    Matsumura, N.2    Watabe, M.3    Nakaki, T.4
  • 4
    • 78651488842 scopus 로고    scopus 로고
    • Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund’s adjuvant-induced inflammatory pain but not for incision-induced post operative pain
    • CrossRef Medline
    • Atianjoh FE, Yaster M, Zhao X, Takamiya K, Xia J, Gauda EB, Huganir RL, Tao YX (2010) Spinal cord protein interacting with C kinase 1 is required for the maintenance of complete Freund’s adjuvant-induced inflammatory pain but not for incision-induced post operative pain. Pain 151:226-234. CrossRef Medline
    • (2010) Pain , vol.151 , pp. 226-234
    • Atianjoh, F.E.1    Yaster, M.2    Zhao, X.3    Takamiya, K.4    Xia, J.5    Gauda, E.B.6    Huganir, R.L.7    Tao, Y.X.8
  • 7
    • 36348963115 scopus 로고    scopus 로고
    • PICK1-ICA69 het-eromeric BAR domain complex regulates synaptic targeting and surface expression of AMPA receptors
    • CrossRef Medline
    • Cao M, Xu J, Shen C, Kam C, Huganir RL, Xia J (2007) PICK1-ICA69 het-eromeric BAR domain complex regulates synaptic targeting and surface expression of AMPA receptors. J Neurosci 27:12945-12956. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 12945-12956
    • Cao, M.1    Xu, J.2    Shen, C.3    Kam, C.4    Huganir, R.L.5    Xia, J.6
  • 8
    • 0037088930 scopus 로고    scopus 로고
    • Expression of a variant form of the glutamate transporter GLTl in neuronal cultures and in neurons and astrocytes in the rat brain
    • Medline
    • Chen W, Aoki C, Mahadomrongkul V, Gruber CE, Wang GJ, Blitzblau R, Irwin N, Rosenberg PA (2002) Expression of a variant form of the glutamate transporter GLTl in neuronal cultures and in neurons and astrocytes in the rat brain. J Neurosci 22:2142-2152. Medline
    • (2002) J Neurosci , vol.22 , pp. 2142-2152
    • Chen, W.1    Aoki, C.2    Mahadomrongkul, V.3    Gruber, C.E.4    Wang, G.J.5    Blitzblau, R.6    Irwin, N.7    Rosenberg, P.A.8
  • 9
    • 0037343974 scopus 로고    scopus 로고
    • The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures
    • CrossRef Medline
    • Chen Y, Swanson RA (2003) The glutamate transporters EAAT2 and EAAT3 mediate cysteine uptake in cortical neuron cultures. J Neurochem 84:1332-1339. CrossRef Medline
    • (2003) J Neurochem , vol.84 , pp. 1332-1339
    • Chen, Y.1    Swanson, R.A.2
  • 10
    • 0030930104 scopus 로고    scopus 로고
    • Non-synaptic localization of the glutamate transporter EAAC1 in cultured hippocampal neurons
    • CrossRef Medline
    • Coco S, Verderio C, Trotti D, Rothstein JD, Volterra A, Matteoli M (1997) Non-synaptic localization of the glutamate transporter EAAC1 in cultured hippocampal neurons. Eur J Neurosci 9:1902-1910. CrossRef Medline
    • (1997) Eur J Neurosci , vol.9 , pp. 1902-1910
    • Coco, S.1    Verderio, C.2    Trotti, D.3    Rothstein, J.D.4    Volterra, A.5    Matteoli, M.6
  • 15
    • 0034672943 scopus 로고    scopus 로고
    • Metabolism and functions of glutathione in brain
    • CrossRef Medline
    • Dringen R (2000) Metabolism and functions of glutathione in brain. Prog Neurobiol 62:649-671. CrossRef Medline
    • (2000) Prog Neurobiol , vol.62 , pp. 649-671
    • Dringen, R.1
  • 16
    • 84876815801 scopus 로고    scopus 로고
    • May the evaluation of nitrosative stress through selective increase of 2-nitrotyrosine proteins other than nitroalbumin and dominant tyrosine-125/136 nitrosylation of serum α-synuclein serve for diagnosis of sporadic Parkinson’s disease
    • CrossRef Medline
    • Fernandez E, García-Moreno JM, Martín de Pablos A, Chacón J (2013) May the evaluation of nitrosative stress through selective increase of 2-nitrotyrosine proteins other than nitroalbumin and dominant tyrosine-125/136 nitrosylation of serum α-synuclein serve for diagnosis of sporadic Parkinson’s disease? Antioxid Redox Signal 19:912-918. CrossRef Medline
    • (2013) Antioxid Redox Signal , vol.19 , pp. 912-918
    • Fernandez, E.1    García-Moreno, J.M.2    Martín de Pablos, A.3    Chacón, J.4
  • 17
    • 84879550299 scopus 로고    scopus 로고
    • Protein interacting with C kinase and neurological disorders
    • CrossRef Medline
    • Focant MC, Hermans E (2013) Protein interacting with C kinase and neurological disorders. Synapse 67:532-540. CrossRef Medline
    • (2013) Synapse , vol.67 , pp. 532-540
    • Focant, M.C.1    Hermans, E.2
  • 18
    • 4544366121 scopus 로고    scopus 로고
    • Rapid trafficking of the neuronal glutamate transporter, EAAC1: Evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor
    • CrossRef Medline
    • Fournier KM, González MI, Robinson MB (2004) Rapid trafficking of the neuronal glutamate transporter, EAAC1: evidence for distinct trafficking pathways differentially regulated by protein kinase C and platelet-derived growth factor. J Biol Chem 279:34505-34513. CrossRef Medline
    • (2004) J Biol Chem , vol.279 , pp. 34505-34513
    • Fournier, K.M.1    González, M.I.2    Robinson, M.B.3
  • 20
    • 36248960617 scopus 로고    scopus 로고
    • Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1
    • CrossRef Medline
    • González MI, Susarla BT, Fournier KM, Sheldon AL, Robinson MB (2007) Constitutive endocytosis and recycling of the neuronal glutamate transporter, excitatory amino acid carrier 1. J Neurochem 103:1917-1931. CrossRef Medline
    • (2007) J Neurochem , vol.103 , pp. 1917-1931
    • González, M.I.1    Susarla, B.T.2    Fournier, K.M.3    Sheldon, A.L.4    Robinson, M.B.5
  • 21
    • 0018666729 scopus 로고
    • Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoxi-mine)
    • Medline
    • Griffith OW, Meister A (1979) Potent and specific inhibition of glutathione synthesis by buthionine sulfoximine (S-n-butyl homocysteine sulfoxi-mine). J Biol Chem 254:7558-7560. Medline
    • (1979) J Biol Chem , vol.254 , pp. 7558-7560
    • Griffith, O.W.1    Meister, A.2
  • 22
    • 42649135851 scopus 로고    scopus 로고
    • PICK1: A multi-talented modulator of AMPA receptor trafficking
    • CrossRef Medline
    • Hanley JG (2008) PICK1: a multi-talented modulator of AMPA receptor trafficking. Pharmacol Ther 118:152-160. CrossRef Medline
    • (2008) Pharmacol Ther , vol.118 , pp. 152-160
    • Hanley, J.G.1
  • 23
    • 25144522326 scopus 로고    scopus 로고
    • PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking
    • CrossRef Medline
    • Hanley JG, Henley JM (2005) PICK1 is a calcium-sensor for NMDA-induced AMPA receptor trafficking. EMBO J 24:3266-3278. CrossRef Medline
    • (2005) EMBO J , vol.24 , pp. 3266-3278
    • Hanley, J.G.1    Henley, J.M.2
  • 24
    • 84858782079 scopus 로고    scopus 로고
    • AMPK: A nutrient and energy sensor that maintains energy homeostasis
    • CrossRef Medline
    • Hardie DG, Ross FA, Hawley SA (2012) AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat Rev Mol Cell Biol 13:251-262. CrossRef Medline
    • (2012) Nat Rev Mol Cell Biol , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 25
    • 0033961498 scopus 로고    scopus 로고
    • Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus
    • CrossRef Medline
    • He Y, Janssen WG, Rothstein JD, Morrison JH (2000) Differential synaptic localization of the glutamate transporter EAAC1 and glutamate receptor subunit GluR2 in the rat hippocampus. J Comp Neurol 418:255-269. CrossRef Medline
    • (2000) J Comp Neurol , vol.418 , pp. 255-269
    • He, Y.1    Janssen, W.G.2    Rothstein, J.D.3    Morrison, J.H.4
  • 26
    • 0347991771 scopus 로고    scopus 로고
    • Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons
    • CrossRef Medline
    • Himi T, Ikeda M, Yasuhara T, Nishida M, Morita I (2003) Role of neuronal glutamate transporter in the cysteine uptake and intracellular glutathione levels in cultured cortical neurons. J Neural Transm 110:1337-1348. CrossRef Medline
    • (2003) J Neural Transm , vol.110 , pp. 1337-1348
    • Himi, T.1    Ikeda, M.2    Yasuhara, T.3    Nishida, M.4    Morita, I.5
  • 27
    • 33644854568 scopus 로고    scopus 로고
    • Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity
    • CrossRef Medline
    • Jin W, Ge WP, Xu J, Cao M, Peng L, Yung W, Liao D, Duan S, Zhang M, Xia J (2006) Lipid binding regulates synaptic targeting of PICK1, AMPA receptor trafficking, and synaptic plasticity. J Neurosci 26:2380-2390. CrossRef Medline
    • (2006) J Neurosci , vol.26 , pp. 2380-2390
    • Jin, W.1    Ge, W.P.2    Xu, J.3    Cao, M.4    Peng, L.5    Yung, W.6    Liao, D.7    Duan, S.8    Zhang, M.9    Xia, J.10
  • 28
    • 78650271422 scopus 로고    scopus 로고
    • PICK1 regulates the trafficking of ASIC la and acidotoxicity in a BAR domain lipid binding-dependent manner
    • CrossRef Medline
    • Jin W, Shen C, Jing L, Zha XM, Xia J (2010) PICK1 regulates the trafficking of ASIC la and acidotoxicity in a BAR domain lipid binding-dependent manner. Mol Brain 3:39. CrossRef Medline
    • (2010) Mol Brain , vol.3 , pp. 39
    • Jin, W.1    Shen, C.2    Jing, L.3    Zha, X.M.4    Xia, J.5
  • 30
    • 0031790690 scopus 로고    scopus 로고
    • Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction
    • CrossRef Medline
    • Kadar T, Dachir S, Shukitt-Hale B, Levy A (1998) Sub-regional hippocampal vulnerability in various animal models leading to cognitive dysfunction. J Neural Transm 105:987-1004. CrossRef Medline
    • (1998) J Neural Transm , vol.105 , pp. 987-1004
    • Kadar, T.1    Dachir, S.2    Shukitt-Hale, B.3    Levy, A.4
  • 31
    • 35448962920 scopus 로고    scopus 로고
    • Rapid activation of antioxidant defenses by nerve growth factor suppresses reactive oxygen species during neuronal apoptosis: Evidence for a role in cytochrome c redistribution
    • CrossRef Medline
    • Kirkland RA, Saavedra GM, Franklin JL (2007) Rapid activation of antioxidant defenses by nerve growth factor suppresses reactive oxygen species during neuronal apoptosis: evidence for a role in cytochrome c redistribution. J Neurosci 27:11315-11326. CrossRef Medline
    • (2007) J Neurosci , vol.27 , pp. 11315-11326
    • Kirkland, R.A.1    Saavedra, G.M.2    Franklin, J.L.3
  • 32
    • 58149102031 scopus 로고    scopus 로고
    • Cerebrospinal fluid, serum and plasma protein oxidation in Alzheimer’s disease
    • CrossRef Medline
    • Korolainen MA, Pirttilä T (2009) Cerebrospinal fluid, serum and plasma protein oxidation in Alzheimer’s disease. Acta Neurol Scand 119:32-38. CrossRef Medline
    • (2009) Acta Neurol Scand , vol.119 , pp. 32-38
    • Korolainen, M.A.1    Pirttilä, T.2
  • 34
    • 77950682093 scopus 로고    scopus 로고
    • Aberrant Rab 11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington’s disease
    • CrossRef Medline
    • Li X, Valencia A, Sapp E, Masso N, Alexander J, Reeves P, Kegel KB, Aronin N, Difiglia M (2010) Aberrant Rab 11-dependent trafficking of the neuronal glutamate transporter EAAC1 causes oxidative stress and cell death in Huntington’s disease. J Neurosci 30:4552-4561. CrossRef Medline
    • (2010) J Neurosci , vol.30 , pp. 4552-4561
    • Li, X.1    Valencia, A.2    Sapp, E.3    Masso, N.4    Alexander, J.5    Reeves, P.6    Kegel, K.B.7    Aronin, N.8    Difiglia, M.9
  • 35
    • 84893485922 scopus 로고    scopus 로고
    • Pharmacological rescue of Ras signaling, GluAl-dependent synaptic plasticity, and learning deficits in a fragile X model
    • CrossRef Medline
    • Lim CS, Hoang ET, Viar KE, Stornetta RL, Scott MM, Zhu JJ (2014) Pharmacological rescue of Ras signaling, GluAl-dependent synaptic plasticity, and learning deficits in a fragile X model. Genes Dev 28:273-289. CrossRef Medline
    • (2014) Genes Dev , vol.28 , pp. 273-289
    • Lim, C.S.1    Hoang, E.T.2    Viar, K.E.3    Stornetta, R.L.4    Scott, M.M.5    Zhu, J.J.6
  • 37
    • 77954402627 scopus 로고    scopus 로고
    • A newly discovered mutation in PICK1 in a human with globozoospermia
    • CrossRef Medline
    • Liu G, Shi QW, Lu GX (2010) A newly discovered mutation in PICK1 in a human with globozoospermia. Asian J Androl 12:556-560. CrossRef Medline
    • (2010) Asian J Androl , vol.12 , pp. 556-560
    • Liu, G.1    Shi, Q.W.2    Lu, G.X.3
  • 39
    • 84882602942 scopus 로고    scopus 로고
    • Why is CA3 more vulnerable than CA1 in experimental models of controlled cortical impact-induced brain injury
    • CrossRef Medline
    • Mao H, Elkin BS, Genthikatti W, Morrison B 3rd, Yang KH (2013) Why is CA3 more vulnerable than CA1 in experimental models of controlled cortical impact-induced brain injury? J Neurotrauma 30:1521-1530. CrossRef Medline
    • (2013) J Neurotrauma , vol.30 , pp. 1521-1530
    • Mao, H.1    Elkin, B.S.2    Genthikatti, W.3    Morrison, B.4    Yang, K.H.5
  • 42
    • 84897954445 scopus 로고    scopus 로고
    • Microglial dysfunction in brain aging and Alzheimer’s disease
    • CrossRef Medline
    • Mosher KI, Wyss-Coray T (2014) Microglial dysfunction in brain aging and Alzheimer’s disease. Biochem Pharmacol 88:594-604. CrossRef Medline
    • (2014) Biochem Pharmacol , vol.88 , pp. 594-604
    • Mosher, K.I.1    Wyss-Coray, T.2
  • 43
    • 84875790877 scopus 로고    scopus 로고
    • Reactive oxygen species and oxidative stress
    • CrossRef Medline
    • Noh H, Ha H (2011) Reactive oxygen species and oxidative stress. Contrib Nephrol 170:102-112. CrossRef Medline
    • (2011) Contrib Nephrol , vol.170 , pp. 102-112
    • Noh, H.1    Ha, H.2
  • 45
    • 4644287672 scopus 로고    scopus 로고
    • Recycling endosomes supply AMPA receptors for LTP
    • CrossRef Medline
    • Park M, Penick EC, Edwards JG, Kauer JA, Ehlers MD (2004) Recycling endosomes supply AMPA receptors for LTP. Science 305:1972-1975. CrossRef Medline
    • (2004) Science , vol.305 , pp. 1972-1975
    • Park, M.1    Penick, E.C.2    Edwards, J.G.3    Kauer, J.A.4    Ehlers, M.D.5
  • 46
    • 0033858941 scopus 로고    scopus 로고
    • The role of glutathione in DNA damage by potassium bromate in vitro
    • CrossRef Medline
    • Parsons JL, Chipman JK (2000) The role of glutathione in DNA damage by potassium bromate in vitro. Mutagenesis 15:311-316. CrossRef Medline
    • (2000) Mutagenesis , vol.15 , pp. 311-316
    • Parsons, J.L.1    Chipman, J.K.2
  • 47
    • 84857827341 scopus 로고    scopus 로고
    • Oxidative stress
    • CrossRef Medline
    • Preiser JC (2012) Oxidative stress. JPEN J Parenter Enteral Nutr 36:147-154. CrossRef Medline
    • (2012) JPEN J Parenter Enteral Nutr , vol.36 , pp. 147-154
    • Preiser, J.C.1
  • 48
    • 0032568657 scopus 로고    scopus 로고
    • Hydrolysis of GTP on rabl 1 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes
    • CrossRef Medline
    • Ren M, Xu G, Zeng J, De Lemos-Chiarandini C, Adesnik M, Sabatini DD (1998) Hydrolysis of GTP on rabl 1 is required for the direct delivery of transferrin from the pericentriolar recycling compartment to the cell surface but not from sorting endosomes. Proc Natl Acad Sci U S A 95:6187-6192. CrossRef Medline
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 6187-6192
    • Ren, M.1    Xu, G.2    Zeng, J.3    De Lemos-Chiarandini, C.4    Adesnik, M.5    Sabatini, D.D.6
  • 50
    • 0029030610 scopus 로고
    • Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis
    • CrossRef Medline
    • Rothstein JD, Van Kammen M, Levey Al, Martin LJ, Kuncl RW (1995) Selective loss of glial glutamate transporter GLT-1 in amyotrophic lateral sclerosis. Ann Neurol 38:73-84. CrossRef Medline
    • (1995) Ann Neurol , vol.38 , pp. 73-84
    • Rothstein, J.D.1    Van Kammen, M.2    Levey, A.L.3    Martin, L.J.4    Kuncl, R.W.5
  • 51
    • 41949115734 scopus 로고    scopus 로고
    • The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/ GTRAP3-18 protein
    • CrossRef Medline
    • Ruggiero AM, Liu Y, Vidensky S, Maier S, Jung E, Farhan H, Robinson MB, Sitte HH, Rothstein JD (2008) The endoplasmic reticulum exit of glutamate transporter is regulated by the inducible mammalian Yip6b/ GTRAP3-18 protein. J Biol Chem 283:6175-6183. CrossRef Medline
    • (2008) J Biol Chem , vol.283 , pp. 6175-6183
    • Ruggiero, A.M.1    Liu, Y.2    Vidensky, S.3    Maier, S.4    Jung, E.5    Farhan, H.6    Robinson, M.B.7    Sitte, H.H.8    Rothstein, J.D.9
  • 52
    • 34648825386 scopus 로고    scopus 로고
    • D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis
    • CrossRef Medline
    • Sasabe J, Chiba T, Yamada M, Okamoto K, Nishimoto I, Matsuoka M, Aiso S (2006) D-serine is a key determinant of glutamate toxicity in amyotrophic lateral sclerosis. EMBO J 26:4149-4159. CrossRef Medline
    • (2006) EMBO J , vol.26 , pp. 4149-4159
    • Sasabe, J.1    Chiba, T.2    Yamada, M.3    Okamoto, K.4    Nishimoto, I.5    Matsuoka, M.6    Aiso, S.7
  • 53
    • 0033899208 scopus 로고    scopus 로고
    • Glutathione, oxidative stress and neurodegeneration
    • CrossRef Medline
    • Schulz JB, Lindenau J, Seyfried J, Dichgans J (2000) Glutathione, oxidative stress and neurodegeneration. Eur J Biochem 267:4904-4911. CrossRef Medline
    • (2000) Eur J Biochem , vol.267 , pp. 4904-4911
    • Schulz, J.B.1    Lindenau, J.2    Seyfried, J.3    Dichgans, J.4
  • 55
    • 57649233079 scopus 로고    scopus 로고
    • The role of mitochondria in reactive oxygen species metabolism and signaling
    • CrossRef Medline
    • Starkov AA (2008) The role of mitochondria in reactive oxygen species metabolism and signaling. Ann N Y Acad Sci 1147:37-52. CrossRef Medline
    • (2008) Ann N Y Acad Sci , vol.1147 , pp. 37-52
    • Starkov, A.A.1
  • 56
    • 0028898641 scopus 로고
    • PICK1: A perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system
    • CrossRef Medline
    • Staudinger J, Zhou J, Burgess R, Elledge SJ, Olson EN (1995) PICK1: a perinuclear binding protein and substrate for protein kinase C isolated by the yeast two-hybrid system. J Cell Biol 128:263-271. CrossRef Medline
    • (1995) J Cell Biol , vol.128 , pp. 263-271
    • Staudinger, J.1    Zhou, J.2    Burgess, R.3    Elledge, S.J.4    Olson, E.N.5
  • 57
    • 33644872978 scopus 로고    scopus 로고
    • Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression
    • CrossRef Medline
    • Steinberg JP, Takamiya K, Shen Y, Xia J, Rubio ME, Yu S, Jin W, Thomas GM, Linden DJ, Huganir RL (2006) Targeted in vivo mutations of the AMPA receptor subunit GluR2 and its interacting protein PICK1 eliminate cerebellar long-term depression. Neuron 49:845-860. CrossRef Medline
    • (2006) Neuron , vol.49 , pp. 845-860
    • Steinberg, J.P.1    Takamiya, K.2    Shen, Y.3    Xia, J.4    Rubio, M.E.5    Yu, S.6    Jin, W.7    Thomas, G.M.8    Linden, D.J.9    Huganir, R.L.10
  • 60
    • 0032145886 scopus 로고    scopus 로고
    • Glutamate transporters are oxi-dant-vulnerable: A molecular link between oxidative and excitotoxic neurodegeneration
    • CrossRef Medline
    • Trotti D, Danbolt NC, Volterra A (1998) Glutamate transporters are oxi-dant-vulnerable: a molecular link between oxidative and excitotoxic neurodegeneration? Trends Pharmacol Sci 19:328-334. CrossRef Medline
    • (1998) Trends Pharmacol Sci , vol.19 , pp. 328-334
    • Trotti, D.1    Danbolt, N.C.2    Volterra, A.3
  • 61
    • 0035341089 scopus 로고    scopus 로고
    • Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons
    • CrossRef Medline
    • Valencia A, Morán J (2001) Role of oxidative stress in the apoptotic cell death of cultured cerebellar granule neurons. J Neurosci Res 64:284-297. CrossRef Medline
    • (2001) J Neurosci Res , vol.64 , pp. 284-297
    • Valencia, A.1    Morán, J.2
  • 63
    • 84892667812 scopus 로고    scopus 로고
    • C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICKl-PKCalpha complex and cerebellar plasticity
    • CrossRef Medline
    • Wang Z, Wang YN, Sun CL, Yang D, Su LD, Xie YJ, Zhou L, Wang Y, Shen Y (2011) C-terminal domain of ICA69 interacts with PICK1 and acts on trafficking of PICKl-PKCalpha complex and cerebellar plasticity. PLoS One 8:e83862. CrossRef Medline
    • (2011) PLoS One , vol.8
    • Wang, Z.1    Wang, Y.N.2    Sun, C.L.3    Yang, D.4    Su, L.D.5    Xie, Y.J.6    Zhou, L.7    Wang, Y.8    Shen, Y.9
  • 64
    • 0030872150 scopus 로고    scopus 로고
    • Differential vulnerability of the CA1 and CA3 subfields of the hippocampus to superoxide and hydroxyl radicals in vitro
    • CrossRef Medline
    • Wilde GJ, Pringle AK, Wright P, Iannotti F (1997) Differential vulnerability of the CA1 and CA3 subfields of the hippocampus to superoxide and hydroxyl radicals in vitro. J Neurochem 69:883-886. CrossRef Medline
    • (1997) J Neurochem , vol.69 , pp. 883-886
    • Wilde, G.J.1    Pringle, A.K.2    Wright, P.3    Iannotti, F.4
  • 65
    • 0031465419 scopus 로고    scopus 로고
    • Antioxidant defense of the brain: A role for astrocytes
    • CrossRef Medline
    • Wilson JX (1997) Antioxidant defense of the brain: a role for astrocytes. Can J Physiol Pharmacol 75:1149-1163. CrossRef Medline
    • (1997) Can J Physiol Pharmacol , vol.75 , pp. 1149-1163
    • Wilson, J.X.1
  • 66
    • 0033635165 scopus 로고    scopus 로고
    • Cerebellar longterm depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins
    • CrossRef Medline
    • Xia J, Chung HJ, Wihler C, Huganir RL, Linden DJ (2000) Cerebellar longterm depression requires PKC-regulated interactions between GluR2/3 and PDZ domain-containing proteins. Neuron 28:499-510. CrossRef Medline
    • (2000) Neuron , vol.28 , pp. 499-510
    • Xia, J.1    Chung, H.J.2    Wihler, C.3    Huganir, R.L.4    Linden, D.J.5
  • 67
    • 84929350648 scopus 로고    scopus 로고
    • Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum
    • CrossRef Medline
    • Xie YJ, Zhou L, Jiang N, Zhang N, Zou N, Zhou L, Wang Y, Cowell JK, Shen Y (2015) Essential roles of leucine-rich glioma inactivated 1 in the development of embryonic and postnatal cerebellum. Sci Rep 5:7827. CrossRef Medline
    • (2015) Sci Rep , vol.5 , pp. 7827
    • Xie, Y.J.1    Zhou, L.2    Jiang, N.3    Zhang, N.4    Zou, N.5    Zhou, L.6    Wang, Y.7    Cowell, J.K.8    Shen, Y.9
  • 68
    • 34250160169 scopus 로고    scopus 로고
    • Structure and function of PICK 1
    • CrossRef Medline
    • Xu J, Xia J (2006) Structure and function of PICK 1. NeuroSignals 15:190-201. CrossRef Medline
    • (2006) NeuroSignals , vol.15 , pp. 190-201
    • Xu, J.1    Xia, J.2
  • 69
    • 84909953386 scopus 로고    scopus 로고
    • PICK1 mediates synaptic recruitment of AMPA receptors at neurexin-induced postsynaptic sites
    • CrossRef Medline
    • Xu J, Kam C, Luo JH, Xia J (2014) PICK1 mediates synaptic recruitment of AMPA receptors at neurexin-induced postsynaptic sites. J Neurosci 34: 15415-15424. CrossRef Medline
    • (2014) J Neurosci , vol.34 , pp. 15415-15424
    • Xu, J.1    Kam, C.2    Luo, J.H.3    Xia, J.4
  • 71
    • 0029891464 scopus 로고    scopus 로고
    • Interaction of L-cysteine with a human excitatory amino acid transporter
    • CrossRef Medline
    • Zerangue N, Kavanaugh MP (1996) Interaction of L-cysteine with a human excitatory amino acid transporter. J Physiol 493:419-423. CrossRef Medline
    • (1996) J Physiol , vol.493 , pp. 419-423
    • Zerangue, N.1    Kavanaugh, M.P.2
  • 72
    • 84866715394 scopus 로고    scopus 로고
    • Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons
    • CrossRef Medline
    • Zhu J, Shao CY, Yang W, Zhang XM, Wu ZY, Zhou L, Wang XX, Li YH, Xia J, Luo JH, Shen Y (2012) Chronic zinc exposure decreases the surface expression of NR2A-containing NMDA receptors in cultured hippocampal neurons. PLoS One 7:e46012. CrossRef Medline
    • (2012) PLoS One , vol.7
    • Zhu, J.1    Shao, C.Y.2    Yang, W.3    Zhang, X.M.4    Wu, Z.Y.5    Zhou, L.6    Wang, X.X.7    Li, Y.H.8    Xia, J.9    Luo, J.H.10    Shen, Y.11


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.