Seven novel deleterious LEPR mutations found in early-onset obesity: A Δexon6-8 shared by subjects from Reunion Island, France, suggests a founder effect

Journal of Clinical Endocrinology and Metabolism

Volumn 100, Issue 5, 2015, Pages E757-E766

  Huvenne, Hélène ^a,b,c,d   Le Beyec, Johanne ^a,b,c   Pépin, Dominique ^a   Alili, Rohia ^a   Kherchiche, Patricia Pigeon ^e   Jeannic, Erwan ^f   Frelut, Marie Laure ^g   Lacorte, Jean Marc ^a,b,c   Nicolino, Marc ^h   Viard, Amélie ⁱ   Laville, Martine ^j   Ledoux, Séverine ^k   Tounian, Patrick ^a,c,l   Poitou, Christine ^a,b,c   Dubern, Béatrice ^a,c,l   Clément, Karine ^a,b,c  

^a PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c INSERM   (France)

^d HÔPITAL SAINT VINCENT DE PAUL   (France)

^e Department of Pediatrics   (France)

^f St François d'Assise Association   (France)

^g BICÊTRE HOSPITAL   (France)

^h Children's and Women's Hospital   (France)

ⁱ SERVICE DE DERMATOLOGIE   (France)

^j CENTRE HOSPITALIER LYON SUD   (France)

^k HÔPITAL LOUIS MOURIER   (France)

^l ARMAND TROUSSEAU HOSPITAL   (France)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN RECEPTOR;

ADOLESCENT; ADULT; ARTICLE; BARIATRIC SURGERY; BODY COMPOSITION; CHILD; CLINICAL ARTICLE; CONTROLLED STUDY; DISEASE SEVERITY; EXON; FEMALE; FOUNDER EFFECT; FRAMESHIFT MUTATION; FRANCE; GENE; GENE DELETION; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC SCREENING; HUMAN; HYPOGONADOTROPIC HYPOGONADISM; IMPULSIVENESS; LEPR GENE; MALE; OBESITY; ONSET AGE; OVERLAPPING GENE; PHENOTYPE; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; PROSPECTIVE STUDY; TREATMENT OUTCOME; WEIGHT REDUCTION; YOUNG ADULT; GENETICS; GENOTYPE; MIDDLE AGED; MUTATION;

ADULT; BODY COMPOSITION; EXONS; FEMALE; FOUNDER EFFECT; FRANCE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; MUTATION; OBESITY; PHENOTYPE; RECEPTORS, LEPTIN;

EID: 84929340500     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2015-1036     Document Type: Article

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