Novel LEPR mutations in obese Pakistani children identified by PCR-based enrichment and next generation sequencing

Obesity

Volumn 22, Issue 4, 2014, Pages 1112-1117

  Saeed, Sadia ^a   Bonnefond, Amélie ^b,c,d   Manzoor, Jaida ^e   Philippe, Julien ^b,c,d   Durand, Emmanuelle ^b,c,d   Arshad, Mohsin ^f   Sand, Olivier ^b,c,d   Butt, Taeed A ^e   Falchi, Mario ^a   Arslan, Muhammad ^f,g   Froguel, Philippe ^a,b,c,d,h  

^a IMPERIAL COLLEGE LONDON   (United Kingdom)

^b EGID FR3508 European Genomics Institute of Diabetes   (France)

^c INSTITUT PASTEUR DE LILLE   (France)

^d UNIV LILLE   (France)

^e CHILDREN S HOSPITAL   (Pakistan)

^f FORMAN CHRISTIAN COLLEGE A CHARTERED UNIVERSITY   (Pakistan)

^g UNIVERSITY OF LAHORE   (Pakistan)

^h HAMAD BIN KHALIFA UNIVERSITY   (Qatar)

Author keywords

[No Author keywords available]

Indexed keywords

LEPTIN RECEPTOR; MELANOCORTIN 4 RECEPTOR; LEPTIN RECEPTOR, HUMAN; MC4R PROTEIN, HUMAN;

ARTICLE; CHILD; CHILD HEALTH; COHORT ANALYSIS; DISEASE SEVERITY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE; GENE MUTATION; GENE SEQUENCE; GENETIC ASSOCIATION; GENETIC CODE; GENETIC SCREENING; GOLD STANDARD; HUMAN; LEPR GENE; MALE; MC4R GENE; MOLECULAR DIAGNOSIS; NEXT GENERATION SEQUENCING; OBESITY; PAKISTAN; PHENOTYPE; POLYMERASE CHAIN REACTION; PREVALENCE; CASE CONTROL STUDY; CASE REPORT; CONSANGUINITY; DNA SEQUENCE; ETHNOLOGY; EXON; GENETICS; HOMOZYGOTE; INFANT; MUTATION; PEDIGREE; SEVERITY OF ILLNESS INDEX;

CASE-CONTROL STUDIES; COHORT STUDIES; CONSANGUINITY; EXONS; FEMALE; HOMOZYGOTE; HUMANS; INFANT; MALE; MUTATION; OBESITY; PAKISTAN; PEDIGREE; PHENOTYPE; POLYMERASE CHAIN REACTION; RECEPTOR, MELANOCORTIN, TYPE 4; RECEPTORS, LEPTIN; SEQUENCE ANALYSIS, DNA; SEVERITY OF ILLNESS INDEX;

EID: 84897459909     PISSN: 19307381     EISSN: 1930739X     Source Type: Journal    
DOI: 10.1002/oby.20667     Document Type: Article

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