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Volumn 62, Issue 1, 2015, Pages 23-38

State of research in the field of the creation of plant vaccines for veterinary use

Author keywords

Biosafety; Expression systems; Plant vaccines; Recombinant proteins; Transgenic plants; Veterinary

Indexed keywords


EID: 84929330114     PISSN: 10214437     EISSN: None     Source Type: Journal    
DOI: 10.1134/S1021443715010100     Document Type: Review
Times cited : (5)

References (92)
  • 1
    • 58149112262 scopus 로고    scopus 로고
    • Plant-produced vaccines: Promise and reality
    • Rybicki, E. P., Plant-produced vaccines: promise and reality, Drug Discov. Today, 2009, vol. 14, pp. 16-24.
    • (2009) Drug Discov. Today , vol.14 , pp. 16-24
    • Rybicki, E.P.1
  • 4
    • 84860382362 scopus 로고    scopus 로고
    • Clinical trials fuel the promise of plant-derived vaccines
    • Hefferon, K., Clinical trials fuel the promise of plant-derived vaccines, Am. J. Chin. Med., 2010, vol. 7, pp. 30-37.
    • (2010) Am. J. Chin. Med , vol.7 , pp. 30-37
    • Hefferon, K.1
  • 5
    • 0027048769 scopus 로고
    • Expression of hepatitis B surface antigen in transgenic plants
    • Mason, H. S., Lam, M.-K. D., and Arntzen, C. J., Expression of hepatitis B surface antigen in transgenic plants, Proc. Natl. Acad. Sci. USA, 1992, vol. 89, pp. 11745-11749.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 11745-11749
    • Mason, H.S.1    Lam, M.-K.D.2    Arntzen, C.J.3
  • 6
    • 0029055060 scopus 로고
    • Oral immunization with a recombinant bacterial anti-gen produced in transgenic plants
    • Haq, T., Mason, H. S., Clements, J. D., and Arntzen, C. J., Oral immunization with a recombinant bacterial anti-gen produced in transgenic plants, Science, 1995, vol. 268, pp. 714-716.
    • (1995) Science , vol.268 , pp. 714-716
    • Haq, T.1    Mason, H.S.2    Clements, J.D.3    Arntzen, C.J.4
  • 7
    • 0032146489 scopus 로고    scopus 로고
    • Edible vaccine protects mice against Escher-ichia coli heat-labile enterotoxin (LT): Potatoes express-ing a synthetic LT-B gene
    • Mason, H. S., Haq, T. A., Clements, J. D., and Arn-tzen, C. J., Edible vaccine protects mice against Escher-ichia coli heat-labile enterotoxin (LT): potatoes express-ing a synthetic LT-B gene, Vaccine, 1998, vol. 16, pp. 1336-1343.
    • (1998) Vaccine , vol.16 , pp. 1336-1343
    • Mason, H.S.1    Haq, T.A.2    Clements, J.D.3    Arntzen, C.J.4
  • 8
    • 0031935290 scopus 로고    scopus 로고
    • Effi-cacy of food plant-based oral cholera toxin B subunit vaccine
    • Arakawa, T., Chong, D. K. X., and Langridge, W., Effi-cacy of food plant-based oral cholera toxin B subunit vaccine, Nat. Biotechnol., 1998, vol. 16, pp. 292-297.
    • (1998) Nat. Biotechnol , vol.16 , pp. 292-297
    • Arakawa, T.1    Chong, D.K.X.2    Langridge, W.3
  • 9
    • 0031863854 scopus 로고    scopus 로고
    • Immunogenicity in humans of a recombinant bacte-rial antigen delivered in a transgenic potato
    • Tacket, C. O., Mason, H. S., Losonsky, G., Clements, J. D., Levine, M. M., and Arntzen, C. J., Immunogenicity in humans of a recombinant bacte-rial antigen delivered in a transgenic potato, Nat. Med., 1998, vol. 4, pp. 607-609.
    • (1998) Nat. Med , vol.4 , pp. 607-609
    • Tacket, C.O.1    Mason, H.S.2    Losonsky, G.3    Clements, J.D.4    Levine, M.M.5    Arntzen, C.J.6
  • 10
    • 33845650824 scopus 로고    scopus 로고
    • Receptor-mediated oral delivery of a bioencapsulated green fluorescent protein expressed in transgenic chlo-roplasts into the mouse circulatory system
    • Limaye, A., Koya, V., Samsam, M., and Daniell, H., Receptor-mediated oral delivery of a bioencapsulated green fluorescent protein expressed in transgenic chlo-roplasts into the mouse circulatory system, FASEB J., 2006, vol. 20, pp. 959-961.
    • (2006) FASEB J , vol.20 , pp. 959-961
    • Limaye, A.1    Koya, V.2    Samsam, M.3    Daniell, H.4
  • 11
    • 84856970457 scopus 로고    scopus 로고
    • Delivery of plant-made vaccines and therapeutics
    • Pelosi, A., Shepherd, R., and Walmsley, A. M., Delivery of plant-made vaccines and therapeutics, Biotechnol. Adv., 2012, vol. 30, pp. 440-448.
    • (2012) Biotechnol. Adv , vol.30 , pp. 440-448
    • Pelosi, A.1    Shepherd, R.2    Walmsley, A.M.3
  • 12
    • 79957725162 scopus 로고    scopus 로고
    • Defending the mucosa: Adjuvant and carrier formula-tions for mucosal immunity
    • Lawson, L. B., Norton, E. B., and Clements, J. D., Defending the mucosa: adjuvant and carrier formula-tions for mucosal immunity, Curr. Opin. Immunol., 2011, vol. 23, pp. 414-420.
    • (2011) Curr. Opin. Immunol , vol.23 , pp. 414-420
    • Lawson, L.B.1    Norton, E.B.2    Clements, J.D.3
  • 13
    • 34447099136 scopus 로고    scopus 로고
    • Induction of secretory immunity and memory at mucosal surfaces
    • Brandtzaeg, P., Induction of secretory immunity and memory at mucosal surfaces, Vaccine, 2007, vol. 25, pp. 5467-5484.
    • (2007) Vaccine , vol.25 , pp. 5467-5484
    • Brandtzaeg, P.1
  • 14
    • 84878850344 scopus 로고    scopus 로고
    • Oral delivery of human biopharmaceuti-cals autoantigens and vaccine antigens bioencapsu-lated in plant cells
    • Kwon, K. C., Verma, D., Singh, N. D., Herzog, R., and Daniell, H., Oral delivery of human biopharmaceuti-cals, autoantigens and vaccine antigens bioencapsu-lated in plant cells, Adv. Drug Deliv. Rev., 2012, vol. 65, pp. 782-799.
    • (2012) Adv. Drug Deliv. Rev , vol.65 , pp. 782-799
    • Kwon, K.C.1    Verma, D.2    Singh, N.D.3    Herzog, R.4    Daniell, H.5
  • 15
    • 77957327721 scopus 로고    scopus 로고
    • The mucosal immune response to plant-derived vaccines
    • Hefferon, K. L., The mucosal immune response to plant-derived vaccines, Pharm. Res., 2010, vol. 27, pp. 2040-2042.
    • (2010) Pharm. Res , vol.27 , pp. 2040-2042
    • Hefferon, K.L.1
  • 16
    • 1542291118 scopus 로고    scopus 로고
    • Posttranslational modifica-tion of therapeutic proteins in plants
    • Gomord, V. and Faye, L., Posttranslational modifica-tion of therapeutic proteins in plants, Curr. Opin. Plant Biol., 2004, vol. 7, pp. 171-181.
    • (2004) Curr. Opin. Plant Biol , vol.7 , pp. 171-181
    • Gomord, V.1    Faye, L.2
  • 18
    • 79955504025 scopus 로고    scopus 로고
    • The economic potential of plant-made pharmaceuticals in the manu-facture of biologic pharmaceuticals
    • Kaufman, J. and Kalaitzandonakes, N., The economic potential of plant-made pharmaceuticals in the manu-facture of biologic pharmaceuticals, J. Commerc. Bio-technol., 2011, vol. 17, pp. 173-182.
    • (2011) J. Commerc. Bio-technol , vol.17 , pp. 173-182
    • Kaufman, J.1    Kalaitzandonakes, N.2
  • 21
    • 70349840725 scopus 로고    scopus 로고
    • Stability of a soybean seed-derived vaccine antigen following long-term storage processing and transport in the absence of a cold chain
    • Oakes, J. L., Bost, K. L., and Piller, K. J., Stability of a soybean seed-derived vaccine antigen following long-term storage, processing and transport in the absence of a cold chain, J. Sci. Food Agric., 2009, vol. 89, pp. 2191-2199.
    • (2009) J. Sci. Food Agric , vol.89 , pp. 2191-2199
    • Oakes, J.L.1    Bost, K.L.2    Piller, K.J.3
  • 22
    • 33745085830 scopus 로고    scopus 로고
    • Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein
    • Zhang, X., Buehner, N. A., Hutson, A. M., Estes, M. K., and Mason, H. S., Tomato is a highly effective vehicle for expression and oral immunization with Norwalk virus capsid protein, Plant Biotechnol. J., 2006, vol. 4, pp. 419-432.
    • (2006) Plant Biotechnol. J , vol.4 , pp. 419-432
    • Zhang, X.1    Buehner, N.A.2    Hutson, A.M.3    Estes, M.K.4    Mason, H.S.5
  • 23
    • 84859299737 scopus 로고    scopus 로고
    • Production of plant made pharma-ceuticals: From plant host to functional protein
    • Nagels, B., Weterings, K., Callewaert, N., and van Damme, E. J. M., Production of plant made pharma-ceuticals: from plant host to functional protein, CRC Crit. Rev. Plant Sci., 2012, vol. 31, pp. 148-180.
    • (2012) CRC Crit. Rev. Plant Sci , vol.31 , pp. 148-180
    • Nagels, B.1    Weterings, K.2    Callewaert, N.3    van Damme, E.J.M.4
  • 24
    • 33749860977 scopus 로고    scopus 로고
    • Post-translational modifica-tions in the context of therapeutic proteins
    • Walsh, G. and Jefferis, R., Post-translational modifica-tions in the context of therapeutic proteins, Nat. Bio-technol., 2006, vol. 24, pp. 1241-1252.
    • (2006) Nat. Bio-technol , vol.24 , pp. 1241-1252
    • Walsh, G.1    Jefferis, R.2
  • 25
    • 37249011824 scopus 로고    scopus 로고
    • Current achievements in the production of complex biopharmaceuticals with moss bioreactors
    • Decker, E. L. and Reski, R., Current achievements in the production of complex biopharmaceuticals with moss bioreactors, Bioprocess Biosyst. Eng., 2008, vol. 31, pp. 3-9.
    • (2008) Bioprocess Biosyst. Eng , vol.31 , pp. 3-9
    • Decker, E.L.1    Reski, R.2
  • 28
    • 77952839864 scopus 로고    scopus 로고
    • Transcriptional gene silencing in plants
    • Marenkova, T. V. and Deineko, E. V., Transcriptional gene silencing in plants, Russ. J. Genet., 2010, vol. 46, pp. 581-592.
    • (2010) Russ. J. Genet , vol.46 , pp. 581-592
    • Marenkova, T.V.1    Deineko, E.V.2
  • 30
    • 77954863747 scopus 로고    scopus 로고
    • Production of heterologous proteins in plants: Strategies for optimal expression
    • Desai, P. N., Shrivastava, N., and Padh, H., Production of heterologous proteins in plants: strategies for optimal expression, Biotechnol. Adv., 2010, vol. 28, pp. 427-435.
    • (2010) Biotechnol. Adv , vol.28 , pp. 427-435
    • Desai, P.N.1    Shrivastava, N.2    Padh, H.3
  • 32
    • 58849157867 scopus 로고    scopus 로고
    • Exhaustion of the chloroplast protein synthesis capac-ity by massive expression of a highly stable protein anti-biotic
    • Oey, M., Lohse, M., Kreikemeyer, B., and Bock, R., Exhaustion of the chloroplast protein synthesis capac-ity by massive expression of a highly stable protein anti-biotic, Plant J., 2009, vol. 57, pp. 436-445.
    • (2009) Plant J , vol.57 , pp. 436-445
    • Oey, M.1    Lohse, M.2    Kreikemeyer, B.3    Bock, R.4
  • 33
    • 80053072127 scopus 로고    scopus 로고
    • Metabolic adaptation in transplastomic plants massively accumu-lating recombinant proteins
    • Bally, J., Job, C., Belghazi, M., and Job, D., Metabolic adaptation in transplastomic plants massively accumu-lating recombinant proteins, PLoS One, 2011, vol. 6: e25289.
    • (2011) PLoS One , vol.6
    • Bally, J.1    Job, C.2    Belghazi, M.3    Job, D.4
  • 35
    • 0035162968 scopus 로고    scopus 로고
    • Overexpression of the Bt cry2Aa2 operon in chloroplasts leads to formation of insecticidal crys-tals
    • De Cosa, B., Moar, W., Lee, S. B., Miller, M., and Daniell, H., Overexpression of the Bt cry2Aa2 operon in chloroplasts leads to formation of insecticidal crys-tals, Nat. Biotechnol., 2001, vol. 19, pp. 71-74.
    • (2001) Nat. Biotechnol , vol.19 , pp. 71-74
    • De Cosa, B.1    Moar, W.2    Lee, S.B.3    Miller, M.4    Daniell, H.5
  • 36
    • 37249014420 scopus 로고    scopus 로고
    • Chloroplast vector systems for biotechnology applications
    • Verma, D. and Daniell, H., Chloroplast vector systems for biotechnology applications, Plant Physiol., 2007, vol. 145, pp. 1129-1143.
    • (2007) Plant Physiol , vol.145 , pp. 1129-1143
    • Verma, D.1    Daniell, H.2
  • 37
    • 34249860016 scopus 로고    scopus 로고
    • Determining the transgene containment level provided by chloroplast transformation
    • Ruf, S., Karcher, D., and Bock, R., Determining the transgene containment level provided by chloroplast transformation, Proc. Natl. Acad. Sci. USA, 2007, vol. 104, pp. 6998-7002.
    • (2007) Proc. Natl. Acad. Sci. USA , vol.104 , pp. 6998-7002
    • Ruf, S.1    Karcher, D.2    Bock, R.3
  • 38
    • 0035979785 scopus 로고    scopus 로고
    • Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts
    • Daniell, H., Lee, S. B., Panchal, T., and Wiebe, P. O., Expression of the native cholera toxin B subunit gene and assembly as functional oligomers in transgenic tobacco chloroplasts, J. Mol. Biol., 2001, vol. 311, pp. 1001-1009.
    • (2001) J. Mol. Biol , vol.311 , pp. 1001-1009
    • Daniell, H.1    Lee, S.B.2    Panchal, T.3    Wiebe, P.O.4
  • 39
    • 0037283651 scopus 로고    scopus 로고
    • Chloroplast expression of His-tagged GUS-fusions: A general strategy to over-produce and purify foreign proteins using transplas-tomic plants as bioreactors
    • Leelavathi, S. and Reddy, V. S., Chloroplast expression of His-tagged GUS-fusions: a general strategy to over-produce and purify foreign proteins using transplas-tomic plants as bioreactors, Mol. Breed., 2003, vol. 11, pp. 49-58.
    • (2003) Mol. Breed , vol.11 , pp. 49-58
    • Leelavathi, S.1    Reddy, V.S.2
  • 40
    • 0037283514 scopus 로고    scopus 로고
    • Accumulation of trehalose within transgenic chloro-plasts confers drought tolerance
    • Lee, S. B., Kwon, H. B., Kwon, S. J., Park, S. C., Jeong, M. J., Han, S. E., Byun, M. O., and Daniell, H., Accumulation of trehalose within transgenic chloro-plasts confers drought tolerance, Mol. Breed., 2003, vol. 11, pp. 1-13.
    • (2003) Mol. Breed , vol.11 , pp. 1-13
    • Lee, S.B.1    Kwon, H.B.2    Kwon, S.J.3    Park, S.C.4    Jeong, M.J.5    Han, S.E.6    Byun, M.O.7    Daniell, H.8
  • 41
    • 65549134575 scopus 로고    scopus 로고
    • Plants as bioreactors for the production of vaccine anti-gens
    • Tiwari, S., Verma, P. C., Singh, P. K., and Tuli, R., Plants as bioreactors for the production of vaccine anti-gens, Biotechnol. Adv., 2009, vol. 27, pp. 449-467.
    • (2009) Biotechnol. Adv , vol.27 , pp. 449-467
    • Tiwari, S.1    Verma, P.C.2    Singh, P.K.3    Tuli, R.4
  • 42
    • 79952699968 scopus 로고    scopus 로고
    • Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures
    • Xu, J., Ge, X., and Dolan, M. C., Towards high-yield production of pharmaceutical proteins with plant cell suspension cultures, Biotechnol. Adv., 2011, vol. 29, pp. 278-299.
    • (2011) Biotechnol. Adv , vol.29 , pp. 278-299
    • Xu, J.1    Ge, X.2    Dolan, M.C.3
  • 43
    • 0032035334 scopus 로고    scopus 로고
    • Position effects and epigenetic silencing of plant transgenes
    • Matzke, A. J. and Matzke, M. A., Position effects and epigenetic silencing of plant transgenes, Curr. Opin. Plant Biol., 1998, vol. 1, pp. 142-148.
    • (1998) Curr. Opin. Plant Biol , vol.1 , pp. 142-148
    • Matzke, A.J.1    Matzke, M.A.2
  • 44
    • 84856967266 scopus 로고    scopus 로고
    • Bioreactor systems for in vitro production of foreign proteins using plant cell cultures
    • Huang, T. K. and McDonald, K. A., Bioreactor systems for in vitro production of foreign proteins using plant cell cultures, Biotechnol. Adv., 2012, vol. 30, pp. 398-409.
    • (2012) Biotechnol. Adv , vol.30 , pp. 398-409
    • Huang, T.K.1    McDonald, K.A.2
  • 46
    • 77956747852 scopus 로고    scopus 로고
    • Micro-algae come of age as a platform for recombinant protein production
    • Specht, E., Miyake-Stoner, S., and Mayfield, S., Micro-algae come of age as a platform for recombinant protein production, Biotechnol. Lett., 2010, vol. 32, pp. 1373-1383.
    • (2010) Biotechnol. Lett , vol.32 , pp. 1373-1383
    • Specht, E.1    Miyake-Stoner, S.2    Mayfield, S.3
  • 47
    • 0042862830 scopus 로고    scopus 로고
    • Foot-and-mouth disease virus VP1 pro-tein fused with cholera toxin B subunit expressed in Chlamydomonas reinhardtii chloroplast
    • Sun, M., Qian, K., Su, N., Chang, H., Liu, J., Shen, G., and Chen, G., Foot-and-mouth disease virus VP1 pro-tein fused with cholera toxin B subunit expressed in Chlamydomonas reinhardtii chloroplast, Biotechnol. Lett., 2003, vol. 25, pp. 1087-1092.
    • (2003) Biotechnol. Lett , vol.25 , pp. 1087-1092
    • Sun, M.1    Qian, K.2    Su, N.3    Chang, H.4    Liu, J.5    Shen, G.6    Chen, G.7
  • 48
    • 73749088691 scopus 로고    scopus 로고
    • Heat-stable oral alga-based vaccine pro-tects mice from Staphylococcus aureus infection
    • Dreesen, I. A. J., Charpin-El, Hamri, G., and Fuss-enegger, M., Heat-stable oral alga-based vaccine pro-tects mice from Staphylococcus aureus infection, J. Bio-technol., 2010, vol. 145, pp. 273-280.
    • (2010) J. Bio-technol , vol.145 , pp. 273-280
    • Dreesen, I.A.J.1    Charpin-El Hamri, G.2    Fussenegger, M.3
  • 50
    • 33846809293 scopus 로고    scopus 로고
    • Recombination and expression of classical swine fever virus (CSFV) structural protein E2 gene in Chlamydomonas rein-hardtii chroloplasts
    • He, D. M., Qian, K. X., Shen, G. F., Zhang, Z. F., Li, Y. N., Su, Z. L., and Shao, H. B., Recombination and expression of classical swine fever virus (CSFV) structural protein E2 gene in Chlamydomonas rein-hardtii chroloplasts, Colloids Surf. B: Biointerfaces, 2007, vol. 55, pp. 26-30.
    • (2007) Colloids Surf. B: Biointerfaces , vol.55 , pp. 26-30
    • He, D.M.1    Qian, K.X.2    Shen, G.F.3    Zhang, Z.F.4    Li, Y.N.5    Su, Z.L.6    Shao, H.B.7
  • 51
    • 34147095513 scopus 로고    scopus 로고
    • Viral vec-tors for the expression of proteins in plants
    • Gleba, Y., Klimyuk, V., and Marillonnet, S., Viral vec-tors for the expression of proteins in plants, Curr. Opin. Biotechnol., 2007, vol. 18, pp. 134-141.
    • (2007) Curr. Opin. Biotechnol , vol.18 , pp. 134-141
    • Gleba, Y.1    Klimyuk, V.2    Marillonnet, S.3
  • 52
    • 58149119503 scopus 로고    scopus 로고
    • Agrobacterium-mediated transient expression as an approach to production of recombi-nant proteins in plants
    • Sheludko, Y. V., Agrobacterium-mediated transient expression as an approach to production of recombi-nant proteins in plants, Recent Pat. Biotechnol., 2008, vol. 2, pp. 198-208.
    • (2008) Recent Pat. Biotechnol , vol.2 , pp. 198-208
    • Sheludko, Y.V.1
  • 53
    • 77955516220 scopus 로고    scopus 로고
    • A novel two-component tobacco mosaic virus-based vector system for high-level expression of multiple ther-apeutic proteins including a human monoclonal anti-body in plants
    • Roy, G., Weisburg, S., Rabindran, S., and Yusibov, V., A novel two-component tobacco mosaic virus-based vector system for high-level expression of multiple ther-apeutic proteins including a human monoclonal anti-body in plants, Virology, 2010, vol. 405, pp. 93-99.
    • (2010) Virology , vol.405 , pp. 93-99
    • Roy, G.1    Weisburg, S.2    Rabindran, S.3    Yusibov, V.4
  • 54
    • 14844293838 scopus 로고    scopus 로고
    • Magnifec-tion-a new platform for expressing recombinant vac-cines in plants
    • Gleba, Y., Klimyuk, V., and Marillonnet, S., Magnifec-tion-a new platform for expressing recombinant vac-cines in plants, Vaccine, 2005, vol. 23, pp. 2042-2048.
    • (2005) Vaccine , vol.23 , pp. 2042-2048
    • Gleba, Y.1    Klimyuk, V.2    Marillonnet, S.3
  • 57
    • 33846339774 scopus 로고    scopus 로고
    • Multimerization of peptide antigens for pro-duction of stable immunogens in transgenic plants
    • Gil, F., Reytor, E., Pérez-Filgueira, D. M., and Escrib-ano, J. M., Multimerization of peptide antigens for pro-duction of stable immunogens in transgenic plants, J. Biotechnol., 2007, vol. 128, pp. 512-518.
    • (2007) J. Biotechnol , vol.128 , pp. 512-518
    • Gil, F.1    Reytor, E.2    Pérez-Filgueira, D.M.3    Escribano, J.M.4
  • 59
    • 36849041127 scopus 로고    scopus 로고
    • Induction of protective immunity in swine by recombinant bamboo mosaic virus express-ing foot-and-mouth disease virus epitopes
    • Yang, C. D., Liao, J. T., Lai, C. Y., Jong, M. H., Liang, C. M., Lin, Y. L., Lin, N. S., Hsu, Y. H., and Liang, S. M., Induction of protective immunity in swine by recombinant bamboo mosaic virus express-ing foot-and-mouth disease virus epitopes, BMC Bio-technol, 2007, vol. 7, p. 62.
    • (2007) BMC Bio-technol , vol.7
    • Yang, C.D.1    Liao, J.T.2    Lai, C.Y.3    Jong, M.H.4    Liang, C.M.5    Lin, Y.L.6    Lin, N.S.7    Hsu, Y.H.8    Liang, S.M.9
  • 60
    • 33746950963 scopus 로고    scopus 로고
    • In planta production of two peptides of the classical swine fever virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X
    • Marconi, G., Albertini, E., Barone, P., de Marchis, F., Lico, C., Marusic, C., Rutili, D., Veronesi, F., and Porceddu, A., In planta production of two peptides of the classical swine fever virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X, BMC Bio-technol., 2006, vol. 6, p. 29.
    • (2006) BMC Bio-technol , vol.6
    • Marconi, G.1    Albertini, E.2    Barone, P.3    de Marchis, F.4    Lico, C.5    Marusic, C.6    Rutili, D.7    Veronesi, F.8    Porceddu, A.9
  • 63
    • 1942510862 scopus 로고    scopus 로고
    • A corn-based deliv-ery system for animal vaccines: An oral transmissible gastroenteritis virus vaccine boosts lactogenic immu-nity in swine
    • Lamphear, B. J., Jilka, J. M., Kesl, L., Welter, M., Howard, J. A., and Streatfield, S. J., A corn-based deliv-ery system for animal vaccines: an oral transmissible gastroenteritis virus vaccine boosts lactogenic immu-nity in swine, Vaccine, 2004, vol. 22, pp. 2420-2424.
    • (2004) Vaccine , vol.22 , pp. 2420-2424
    • Lamphear, B.J.1    Jilka, J.M.2    Kesl, L.3    Welter, M.4    Howard, J.A.5    Streatfield, S.J.6
  • 64
    • 0034003792 scopus 로고    scopus 로고
    • Immunogenicity of porcine transmissible gastroenteritis virus spike protein expressed in plants
    • Tuboly, T., Yu, W., Bailey, A., Degrandis, S., Du, S., Erickson, L., and Nagy, E., Immunogenicity of porcine transmissible gastroenteritis virus spike protein expressed in plants, Vaccine, 2000, vol. 18, pp. 2023-2028.
    • (2000) Vaccine , vol.18 , pp. 2023-2028
    • Tuboly, T.1    Yu, W.2    Bailey, A.3    Degrandis, S.4    Du, S.5    Erickson, L.6    Nagy, E.7
  • 65
    • 3142529925 scopus 로고    scopus 로고
    • Oral immunization using tuber extracts from transgenic potato plants expressing rabbit hemorrhagic disease virus capsid protein
    • Martín-Alonso, J. M., Castañón, S., Alonso, P., Parra, F., and Ordás, R., Oral immunization using tuber extracts from transgenic potato plants expressing rabbit hemorrhagic disease virus capsid protein, Transgenic Res., 2003, vol. 12, pp. 127-130.
    • (2003) Transgenic Res , vol.12 , pp. 127-130
    • Martín-Alonso, J.M.1    Castañón, S.2    Alonso, P.3    Parra, F.4    Ordás, R.5
  • 66
    • 67650317922 scopus 로고    scopus 로고
    • Pea-derived vaccines demonstrate high immunoge-nicity and protection in rabbits against rabbit haemor-rhagic disease virus
    • Mikschofsky, H., Schirrmeier, H., Keil, G. M., Lange, B., Polowick, P. L., Keller, W., and Broer, I., Pea-derived vaccines demonstrate high immunoge-nicity and protection in rabbits against rabbit haemor-rhagic disease virus, Plant Biotechnol. J., 2009, vol. 7, pp. 537-549.
    • (2009) Plant Biotechnol. J , vol.7 , pp. 537-549
    • Mikschofsky, H.1    Schirrmeier, H.2    Keil, G.M.3    Lange, B.4    Polowick, P.L.5    Keller, W.6    Broer, I.7
  • 67
    • 79953234180 scopus 로고    scopus 로고
    • Plant-made pharmaceuti-cals: Leading products and production platforms
    • Paul, M. and Ma, J. K. C., Plant-made pharmaceuti-cals: leading products and production platforms, Bio-technol. Appl. Biochem., 2011, vol. 58, pp. 58-67.
    • (2011) Bio-technol. Appl. Biochem , vol.58 , pp. 58-67
    • Paul, M.1    Ma, J.K.C.2
  • 68
    • 0036598120 scopus 로고    scopus 로고
    • Pro-duction of immunogenic VP6 protein of bovine group A rotavirus in transgenic potato plants
    • Matsumura, T., Itchoda, N., and Tsunemitsu, H., Pro-duction of immunogenic VP6 protein of bovine group A rotavirus in transgenic potato plants, Arch. Virol., 2002, vol. 147, pp. 1263-1270.
    • (2002) Arch. Virol , vol.147 , pp. 1263-1270
    • Matsumura, T.1    Itchoda, N.2    Tsunemitsu, H.3
  • 69
    • 0034630854 scopus 로고    scopus 로고
    • Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into viruslike parti-cles
    • O'Brien, G. J., Bryant, C. J., Voogd, C., Greenberg, H. B., Gardner, R. C., and Bellamy, A. R., Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into viruslike parti-cles, Virology, 2000, vol. 270, pp. 444-453.
    • (2000) Virology , vol.270 , pp. 444-453
    • O'Brien, G.J.1    Bryant, C.J.2    Voogd, C.3    Greenberg, H.B.4    Gardner, R.C.5    Bellamy, A.R.6
  • 70
    • 0038732769 scopus 로고    scopus 로고
    • Expression of rotavirus capsid protein VP6 in transgenic potato and its oral immuno-genicity in mice
    • Yu, J. and Langridge, W., Expression of rotavirus capsid protein VP6 in transgenic potato and its oral immuno-genicity in mice, Transgenic Res., 2003, vol. 12, pp. 163-169.
    • (2003) Transgenic Res , vol.12 , pp. 163-169
    • Yu, J.1    Langridge, W.2
  • 73
    • 0033558771 scopus 로고    scopus 로고
    • Induction of a protective antibody response to foot and mouth disease virus in mice fol-lowing oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1
    • Wigdorovitz, A., Carrillo, C., Dus Santos, M. J., Trono, K., Peralta, A., Gómez, M. C., Ríos, R. D., Franzone, P. M., Sadir, A. M., Escribano, J. M., and Borca, M. V., Induction of a protective antibody response to foot and mouth disease virus in mice fol-lowing oral or parenteral immunization with alfalfa transgenic plants expressing the viral structural protein VP1, Virology, 1999, vol. 255, pp. 347-353.
    • (1999) Virology , vol.255 , pp. 347-353
    • Wigdorovitz, A.1    Carrillo, C.2    Dus Santos, M.J.3    Trono, K.4    Peralta, A.5    Gómez, M.C.6    Ríos, R.D.7    Franzone, P.M.8    Sadir, A.M.9    Escribano, J.M.10    Borca, M.V.11
  • 74
    • 54949159300 scopus 로고    scopus 로고
    • Induction of a protective antibody response to FMDV in mice following oral immunization with transgenic Stylosanthes spp. as a feedstuff additive
    • Wang, D. M., Zhu, J. B., Peng, M., and Zhou, P., Induction of a protective antibody response to FMDV in mice following oral immunization with transgenic Stylosanthes spp. as a feedstuff additive, Transgenic Res., 2008, vol. 17, pp. 1163-1170.
    • (2008) Transgenic Res , vol.17 , pp. 1163-1170
    • Wang, D.M.1    Zhu, J.B.2    Peng, M.3    Zhou, P.4
  • 75
    • 0037431204 scopus 로고    scopus 로고
    • Expression of hemagglutinin protein of rinderpest virus in transgenic tobacco and immunogenicity of plant-derived protein in a mouse model
    • Khandelwal, A., Lakshmi, Sita, G., and Shaila, M. S., Expression of hemagglutinin protein of rinderpest virus in transgenic tobacco and immunogenicity of plant-derived protein in a mouse model, Virology, 2003, vol. 308, pp. 207-215.
    • (2003) Virology , vol.308 , pp. 207-215
    • Khandelwal, A.1    Lakshmi Sita, G.2    Shaila, M.S.3
  • 76
    • 2942559029 scopus 로고    scopus 로고
    • Systemic and oral immunogenicity of hemagglutinin protein of rinderpest virus expressed by transgenic peanut plants in a mouse model
    • Khandelwal, A., Renukaradhya, G. J., Rajasekhar, M., Lakshmi, Sita, G., and Shaila, M. S., Systemic and oral immunogenicity of hemagglutinin protein of rinderpest virus expressed by transgenic peanut plants in a mouse model, Virology, 2004, vol. 323, pp. 284-291.
    • (2004) Virology , vol.323 , pp. 284-291
    • Khandelwal, A.1    Renukaradhya, G.J.2    Rajasekhar, M.3    Lakshmi Sita, G.4    Shaila, M.S.5
  • 77
    • 0037360692 scopus 로고    scopus 로고
    • Expression of hemagglutinin protein of rinderpest virus in trans-genic pigeon pea [Cajanus cajan (L.) Millsp.] plants
    • Satyavathi, V. V., Prasad, V., Khandelwal, A., Shaila, M. S., and Lakshmi, Sita, G., Expression of hemagglutinin protein of rinderpest virus in trans-genic pigeon pea [Cajanus cajan (L.) Millsp.] plants, Plant Cell Rep., 2003, vol. 21, pp. 651-658.
    • (2003) Plant Cell Rep , vol.21 , pp. 651-658
    • Satyavathi, V.V.1    Prasad, V.2    Khandelwal, A.3    Shaila, M.S.4    Lakshmi Sita, G.5
  • 78
    • 0033860834 scopus 로고    scopus 로고
    • Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus
    • Gómez, N., Wigdorovitz, A., Castañón, S., Gil, F., Ordás, R., Borca, M. V., and Escribano, J. M., Oral immunogenicity of the plant derived spike protein from swine-transmissible gastroenteritis coronavirus, Arch. Virol., 2000, vol. 145, pp. 1725-1732. 79.
    • (2000) Arch. Virol , vol.145
    • Gómez, N.1    Wigdorovitz, A.2    Castañón, S.3    Gil, F.4    Ordás, R.5    Borca, M.V.6    Escribano, J.M.7
  • 79
    • 18144418171 scopus 로고    scopus 로고
    • Cloning and sequence analysis of the Korean strain of spike gene of porcine epidemic diarrhea virus and expression of its neutraliz-ing epitope in plants
    • Kang, T. J., Seo, J. E., Kim, D. H., Kim, T. G., Jang, Y. S., and Yang, M. S., Cloning and sequence analysis of the Korean strain of spike gene of porcine epidemic diarrhea virus and expression of its neutraliz-ing epitope in plants, Protein Expr. Purif., 2005, vol. 41, pp. 378-383.
    • (2005) Protein Expr. Purif , vol.41 , pp. 378-383
    • Kang, T.J.1    Seo, J.E.2    Kim, D.H.3    Kim, T.G.4    Jang, Y.S.5    Yang, M.S.6
  • 80
    • 33645323201 scopus 로고    scopus 로고
    • Successful oral prime-immunization with VP60 from rabbit haemorrhagic disease virus pro-duced in transgenic plants using different fusion strate-gies
    • Gil, F., Titarenko, E., Terrada, E., Arcalís, E., and Escribano, J. M., Successful oral prime-immunization with VP60 from rabbit haemorrhagic disease virus pro-duced in transgenic plants using different fusion strate-gies, Plant Biotechnol. J., 2006, vol. 4, pp. 135-143.
    • (2006) Plant Biotechnol. J , vol.4 , pp. 135-143
    • Gil, F.1    Titarenko, E.2    Terrada, E.3    Arcalís, E.4    Escribano, J.M.5
  • 82
    • 33845232355 scopus 로고    scopus 로고
    • Expres-sion of the fusion glycoprotein of Newcastle disease virus in transgenic rice and its immunogenicity in mice
    • Yang, Z., Liu, Q., Pan, Z., Yu, H., and Jiao, X., Expres-sion of the fusion glycoprotein of Newcastle disease virus in transgenic rice and its immunogenicity in mice, Vaccine, 2007, vol. 25, pp. 591-598.
    • (2007) Vaccine , vol.25 , pp. 591-598
    • Yang, Z.1    Liu, Q.2    Pan, Z.3    Yu, H.4    Jiao, X.5
  • 83
    • 0042208057 scopus 로고    scopus 로고
    • Expression of immunogenic S1 glycoprotein of infectious bronchitis virus in trans-genic potatoes
    • Zhou, J., Wu, J., Cheng, L., Zheng, X., Gong, H., Shang, S., and Zhou, E., Expression of immunogenic S1 glycoprotein of infectious bronchitis virus in trans-genic potatoes, J. Virol., 2003, vol. 77, pp. 9090-9093.
    • (2003) J. Virol , vol.77 , pp. 9090-9093
    • Zhou, J.1    Wu, J.2    Cheng, L.3    Zheng, X.4    Gong, H.5    Shang, S.6    Zhou, E.7
  • 84
    • 35448979958 scopus 로고    scopus 로고
    • Transient expression of the ectodomain of matrix protein 2 (M2e) of avian influenza A virus in plants
    • Nemchinov, L. G. and Natilla, A., Transient expression of the ectodomain of matrix protein 2 (M2e) of avian influenza A virus in plants, Protein Expr. Purif., 2007, vol. 56, pp. 153-159.
    • (2007) Protein Expr. Purif , vol.56 , pp. 153-159
    • Nemchinov, L.G.1    Natilla, A.2
  • 85
    • 78049494601 scopus 로고    scopus 로고
    • Immunization with plant-expressed hemagglutinin protects chickens from lethal highly pathogenic avian influenza virus H5N1 challenge infection
    • Kalthoff, D., Giritch, A., Geisler, K., Bettmann, U., Klimyuk, V., Hehnen, H.-R., Gleba, Y., and Beer, M., Immunization with plant-expressed hemagglutinin protects chickens from lethal highly pathogenic avian influenza virus H5N1 challenge infection, J. Virol., 2010, vol. 84, pp. 12 002-12 010.
    • (2010) J. Virol , vol.84 , pp. 12002-12010
    • Kalthoff, D.1    Giritch, A.2    Geisler, K.3    Bettmann, U.4    Klimyuk, V.5    Hehnen, H.-R.6    Gleba, Y.7    Beer, M.8
  • 86
    • 84862826200 scopus 로고    scopus 로고
    • Immunogenicity study of plant-made oral subunit vaccine against porcine reproductive and res-piratory syndrome virus (PRRSV)
    • Hu, J., Ni, Y., Dryman, B. A., Meng, X. J., and Zhang, C., Immunogenicity study of plant-made oral subunit vaccine against porcine reproductive and res-piratory syndrome virus (PRRSV), Vaccine, 2012, vol. 30, pp. 2068-2074.
    • (2012) Vaccine , vol.30 , pp. 2068-2074
    • Hu, J.1    Ni, Y.2    Dryman, B.A.3    Meng, X.J.4    Zhang, C.5
  • 89
    • 44649190525 scopus 로고    scopus 로고
    • Development of an edible rabies vaccine in maize using the Vnukovo strain
    • Loza-Rubio, E., Rojas-Anaya, E., Gomez-Lim, M., and Olivera, M. T. J., Development of an edible rabies vaccine in maize using the Vnukovo strain, Dev. Biol. (Basel), 2008, vol. 131, pp. 477-482.
    • (2008) Dev. Biol. (Basel) , vol.131 , pp. 477-482
    • Loza-Rubio, E.1    Rojas-Anaya, E.2    Gomez-Lim, M.3    Olivera, M.T.J.4
  • 90
    • 84864306068 scopus 로고    scopus 로고
    • Induction of a protective immune response to rabies virus in sheep after oral immunization with transgenic maize expressing the rabies virus glycoprotein
    • Loza-Rubio, E., Rojas-Anaya, E., López, J., Olivera-Flores, M. T., Gómez-Lim, M., and Tapia-Pérez, G., Induction of a protective immune response to rabies virus in sheep after oral immunization with transgenic maize, expressing the rabies virus glycoprotein, Vac-cine, 2012, vol. 30, pp. 5551-5556.
    • (2012) Vac-cine , vol.30 , pp. 5551-5556
    • Loza-Rubio, E.1    Rojas-Anaya, E.2    López, J.3    Olivera-Flores, M.T.4    Gómez-Lim, M.5    Tapia-Pérez, G.6


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