In planta production of two peptides of the Classical Swine Fever Virus (CSFV) E2 glycoprotein fused to the coat protein of potato virus X

BMC Biotechnology

Volumn 6, Issue , 2006, Pages

  Marconi, Gianpiero ^a   Albertini, Emidio ^a   Barone, Pierluigi ^a,b   De Marchis, Francesca ^a,c   Lico, Chiara ^d   Marusic, Carla ^d   Rutili, Domenico ^e   Veronesi, Fabio ^a   Porceddu, Andrea ^a,c  

^a UNIVERSITY OF PERUGIA   (Italy)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^c INFN SEZIONE DI PERUGIA   (Italy)

^d ENEA C R CASACCIA   (Italy)

^e ISTITUTO ZOOPROFILATTICO SPERIMENTALE DELL UMBRIA E DELLE MARCHE   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

CLASSICAL SWINE FEVER VIRUS; IMMUNOPROTECTIVE RESPONSE; IN PLANTA PRODUCTION; PEPTIDE ENCODING SEQUENCES;

ANTIGEN-ANTIBODY REACTIONS; POLYPEPTIDES; PROTEINS; RNA; VACCINES; VIRUSES;

BIOTECHNOLOGY;

COAT PROTEIN; EPITOPE; GLYCOPROTEIN E2; HYBRID PROTEIN; SINGLE STRANDED RNA; SYNTHETIC PEPTIDE; VIRUS VACCINE; VIRUS VECTOR;

AMINO ACID SEQUENCE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; FLAVIVIRUS; FREEZING; GENETIC CODE; IMMUNE RESPONSE; IMMUNITY; INFECTION CONTROL; NONHUMAN; PEPTIDE SYNTHESIS; PESTIVIRUS; PLANT VIRUS; POLYACRYLAMIDE GEL ELECTROPHORESIS; POTATO VIRUS X; RABBIT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; VIRION; VIRUS INFECTION; VIRUS REPLICATION; VIRUS TRANSMISSION; WESTERN BLOTTING; WILD BOAR;

ANIMALS; CAPSID PROTEINS; CLASSICAL SWINE FEVER VIRUS; GLYCOPROTEINS; PEPTIDES; PLANTS, GENETICALLY MODIFIED; POTEXVIRUS; PROTEIN ENGINEERING; RABBITS; RECOMBINANT FUSION PROTEINS; TOBACCO; VIRAL PROTEINS;

ANIMALIA; CLASSICAL SWINE FEVER VIRUS; FLAVIVIRIDAE; NICOTIANA BENTHAMIANA; ORYCTOLAGUS CUNICULUS; POTATO VIRUS X; RNA VIRUSES; SOLANUM TUBEROSUM; SUS SCROFA; SUS SCROFA DOMESTICA;

EID: 33746950963     PISSN: 14726750     EISSN: 14726750     Source Type: Journal    
DOI: 10.1186/1472-6750-6-29     Document Type: Article

References (35)

1. Moennig V, Plagemann PGW: The Pestiviruses. Advances in Virus Research 1992, 41:53-98.
2. Moennig V, Floegel-Niesmann G, Greiser-Wilke I: Clinical signs and epidemiology of classical swine fever: A review of new knowledge. Veterinary Journal 2003, 165:11-20.
3. Wengler G, Brandley DW, Collet MS, Heinz FX, Schlesinger RW, Strauss JH: Flaviviridae. In Virus Taxonomy - 6th Report of the International Committee on Taxonomy of Viruses Edited by: Murphy FA, Fauquet CM, Bishop DHL, Ghabrial SA, Jarvis AW, Martelli GP, Mayo MA and Summers MD. New York, Springer-Verlag; 1995:415-427.
4. Lin M, Lin F, Mallory M, Clavijo A: Deletions of structural glyco-protein E2 of classical swine fever virus strain Alfort/187 resolve a linear epitope of monoclonal antibody WH303 and the minimal N-terminal domain essential for binding immunoglobulin G antibodies of a pig hyperimmune serum. Journal of Virology 2000, 74:11619-11625.
5. Vanrijn PA, Vangennip RGP, Demeijer EJ, Moormann RJM: A Preliminary Map of Epitopes on Envelope Glycoprotein-EI of Hcv Strain Brescia. Veterinary Microbiology 1992, 33:221-230.
6. Vanrijn PA, Miedema GKW, Wensvoort G, Vangennip HGP, Moormann RJM: Antigenic Structure of Envelope Glycoprotein EI of Hog-Cholera Virus. Journal of Virology 1994, 68:3934-3942.
7. Dong XN, Wei K, Liu ZQ, Chen YH: Candidate peptide vaccine induced protection against classical swine fever virus. Vaccine 2002, 21:167-173.
8. Edwards S: Survival and inactivation of classical swine fever virus. Veterinary Microbiology 2000, 73:175-181.
9. Kaden V, Lange E, Fischer U, Strebelow G: Oral immunisation of wild boar against classical swine fever: evaluation of the first field study in Germany. Veterinary Microbiology 2000, 73:239-252.
10. Kaden V, Heyne H, Kiupel H, Letz W, Kern B, Lemmer U, Gossger K, Rothe A, Bohme H, Tyrpe P: Oral immunisation of wild boar against classical swine fever: concluding analysis of the recent field trials in Germany. Berliner und Munchener Tierarztliche Wochenschrift 2002, 115:179-185.
11. Paton DJ, Greiser-Wilke I: Classical swine fever - an update. Research in Veterinary Science 2003, 75:169-178.
12. Sala F, Rigano MM, Barbante A, Basso B, Walmsley AM, Castiglione S: Vaccine antigen production in transgenic plants: strategies, gene constructs and perspectives. Vaccine 2003, 21:803-808.
13. Streatfield SJ, Howard JA: Plant-based vaccines. International Journal for Parasitology 2003, 33:479-493.
14. Porta C, Lomonossoff GP: Scope for using plant viruses to present epitopes from animal pathogens. Reviews in Medical Virology 1998, 8:25-41.
15. Koenig R, Torrance L: Antigenic analysis of potato virus X by means of monoclonal antobodies. Journal of General Virology 1986, 67:2145-2151.
16. Marusic C, Rizza P, Lattanzi L, Mancini C, Spada M, Belardelli F, Benvenuto E, Capone I: Chimeric plant virus particles as immunogens for inducing murine and human immune responses against human immunodeficiency virus type 1. Journal of Virology 2001, 75:8434-8439.
17. Dong XN, Chen Y, Wu Y, Chen YH: Candidate multi-peptide-vaccine against classical swine fever virus induced potent immunity with serological marker. Vaccine 2005, 23:3630-3633.
18. Uhde K, Fischer R, Commandeur U: Expression of multiple foreign epitopes presented as synthetic antigens on the surface of Potato virus X particles. Archives of Virology 2005, 150:327-340.
19. Ziegler A, Cowan GH, Torrance L, Ross HA, Davies HV: Facile assessment of cDNA constructs for expression of functional antibodies in plants using the potato virus X vector. Molecular Breeding 2000, 6:327-335.
20. Donnelly MLL, Luke G, Mehrotra A, Li XJ, Hughes LE, Gani D, Ryan MD: Analysis of the aphthovirus 2A/2B polyprotein 'cleavage' mechanism indicates not a proteolytic reaction, but a novel translational effect: a putative ribosomal 'skip'. Journal of General Virology 2001, 82:1013-1025.
21. de Felipe P, Hughes LE, Ryan MD, Brown JD: Co-translational, intraribosomal cleavage of polypeptides by the foot-and-mouth disease virus 2A peptide. Journal of Biological Chemistry 2003, 278:11441-11448.
22. Santa Cruz S, Chapman S, Roberts AG, Roberts IM, Prior DAM, Oparka KJ: Assembly and movement of a plant virus carrying a green fluorescent protein overcoat. Proceedings of the National Academy of Sciences of the United States of America 1996, 93:6286-6290.
23. AbouHaidar MG, Xu H, Hefferon KL: Potexvirus isolation and RNA extraction. Methods Mol Cell Biol 1998, 81:131-143.
24. van Vloten-Doting L, Bol JF, Cornellisen B: Plant virus based vectors for gene transfer will be of limited use because of the high error rate during viral DNA synthesis. Plant Molecular Biology 1985, 4:323-326.
25. Avesani L, Falorni A, Tornielli GB, Marusic C, Porceddu A, Polverari A, Faleri C, Calcinaro F, Pezzotti M: Improved in planta expression of the human islet autoantigen glutamic acid decarboxylase (GAD65). Transgenic Research 2003, 12:203-212.
26. Donson J, Kearney CM, Dawson WO: Systemic expression of a bacterial gene by a tobacco mosaic virus-based vector. Proc Natl Acad Sci U S A 1991, 88:7204-7208.
27. Savelyeva. N, Munday R, Spellerberg MB, Lomonossoff GP, Stevenson FK: Plant viral genes in DNA idiotypic vaccines activate linked CD4(+) T-cell mediated immunity against B-cell malignancies. Nature Biotechnology 2001, 19:760-764.
28. Legocki AB, Miedzinska K, Czaplinska M, Plucieniczak A, Wedrychowicz H: Immunoprotective properties of transgenic plants expressing E2 glycoprotein from CSFV and cysteine protease from Fasciola hepatica. Vaccine 2005, 23:1844-1846.
29. Smolenska L, Roberts IM, Learmonth D, Porter AJ, Harris WJ, Wilson TM, Santa Cruz S: Production of a functional single chain antibody attached to the surface of a plant virus. FEBS letter 1998, 441:379-382.
30. O'Brien GJ, Bryant CJ, Voogd C, Greenberg HB, Gardner RC, Bellamy AR: Rotavirus VP6 expressed by PVX vectors in Nicotiana benthamiana coats PVX rods and also assembles into virus-like particles. Virology 2000, 270:444-453.
31. Alejska M, Figlerowicz M, Malinowska N, Urbanowicz A, Figlerowicz M: A universal BMV-based RNA recombination system-how to search for general rules in RNA recombination. Nucleic Acids Research 2006, 33:e105.
32. Ryan MD, Drew J: Foot-And-Mouth-Disease Virus 2A Oligopeptide Mediated Cleavage of An Artificial Polyprotein. Embo Journal 1994, 13:928-933.
33. Baulcombe DC, Chapman S, Cruz SS: Jellyfish Green Fluorescent Protein As A Reporter for Virus-Infections. Plant Journal 1995, 7:1045-1053.
34. The sainsbury lab: notes for users of the PVX expression vectors 2006 [http://www.jic.bbsrc.ac.uk/sainsbury-lab/dcb/services/instruct.htm].
35. Sambrook J, Russell DW: Molecular cloning: A laboratory manual. Cold Spring Harbor, NY, Cold Spring Harbor Laboratory Press; 2001.