Development of an edible rabies vaccine in maize using the Vnukovo strain

Developments in Biologicals

Volumn 131, Issue , 2008, Pages 477-482

  Loza Rubio, E ^a   Rojas, E ^a   Gomez L ^a   Olivera, M T J ^b   Gomez Lim M A ^c  

^a INSTITUTO NACIONAL DE INVESTIGACIONES FORESTALES   (Mexico)

^b UNIVERSIDAD NACIONAL AUTÓNOMA DE MÉXICO   (Mexico)

^c DEPARTAMENTO DE INGENIERÍA GENÉTICA   (Mexico)

Author keywords

Corn; Edible vaccine; Rabies; Vampire bat; Vnukovo strain

Indexed keywords

GLYCOPROTEIN; NUCLEOPROTEIN; RABIES VACCINE; VIRUS ANTIBODY; VIRUS PROTEIN;

ANIMAL; BAGG ALBINO MOUSE; BIOSYNTHESIS; CONFERENCE PAPER; GENETICS; IMMUNOLOGY; MAIZE; MOUSE; ORAL DRUG ADMINISTRATION; RABIES VIRUS; SERODIAGNOSIS; TRANSGENIC PLANT; VIROLOGY;

ADMINISTRATION, ORAL; ANIMALS; ANTIBODIES, VIRAL; GLYCOPROTEINS; MICE; MICE, INBRED BALB C; NEUTRALIZATION TESTS; NUCLEOPROTEINS; PLANTS, GENETICALLY MODIFIED; RABIES VACCINES; RABIES VIRUS; VIRAL PROTEINS; ZEA MAYS;

EID: 44649190525     PISSN: 14246074     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Conference Paper

References (15)

1. WHO expert consultation on Rabies, 2004. First report: WHO technical report series #931. World Health Organization, Geneva, Switzerland.
2. Wandeler AI: Oral immunization against rabies: afterthoughts and foresight. Schweiz Arch Tierheilk 2000;255-462.
3. Paolazzi CC, Pérez O, De Filippo J: Rabies Vaccine. Mol Biotechnol 1999;11:137-147.
4. Boehm R: Bioproduction of therapeutic proteins in the 21st and the role of plants and plant cell as production platforms. Ann NY Acad Sci 2007;1102:121-134.
5. Streatfield SJ: Mucosal immunization using recombinant plant-based oral vaccines. Methods 2006;38:150-157.
6. Orciari LA, Niezgoda M, Hanlon CA, Shaddock JH, Sanderlin DW, Yager PA, Rupprecht CE: Rapid clearance of SAG-2 rabies virus from dogs after oral vaccination. Vaccine. 2001;19:4511-4518.
7. Smith JS, Yager PA, Baer GM: A rapid fluorescent focus inhibition test (RFFIT) for determining rabies virus neutralizing antibody, in FX Meslin, MM Kaplan, Koprowski H (eds): Laboratory Techniques in Rabies. World Health Organization, 1996, 4th ed, pp 181-192.
8. Loza-Rubio E, Gómez-Lim MA: Production of vaccines and other biological compounds in transgenic plants. Vet Méx 2006;37:441-455.
9. Brouwer C, Bruce W, Maddock S, Avramova Z Bowen B: Suppression of transgene silencing by matrix attachment regions in maize: A dual role for the maize 5' ADH1 matrix attachment region. The Plant Cell 2002;14:2251-2264.
10. Tekoah Y, Ko K, Koprowski H, Harvey DJ, Wormald MR, Dwek RA, et al: Controlled glycosylation of therapeutic antibodies in plants. Arch Biochem Biophys 2004;426:266-278.
11. Yusibov V, Modelska A, Steplewski K, Agadjanyan M, Weiner D, Hooper DC et al: Antigens produced in plants by infection with chimeric plant viruses immunize against rabies virus and HIV-1. PNAS USA 1997;94:5784-5788.
12. Yusibov V, Hooper DC, Spitsin JV, Fleysh N, Kean RB, Mikheeva T, et al: Expression in plants and immunogenicity of plant virus-based experimental rabies vaccine. Vaccine 2002:20:3155-3164.
13. Modelska A, Dietzschold B, Sleysh N, Fu ZF, Steplewski K, Hooper DC, et al: Immunization against rabies with plant-derived antigen. Proc Natl Acad Sci USA 1998;95:2481-2485.
14. Lamphear BJ, Streatfield SJ, Jilka JM, Brooks CA, Barker DK, Turner DD, et al: Delivery of subunit vaccines in maize seed. J Cont Rel 2002;85:169-180.
15. Guerrero-Andrade O, Loza-Rubio E, Olivera FMT, Fehervari BT, Gómez-Lim MA: Expression of the Newcastle disease virus fusion protein in transgenic maize and immunological studies. Transgenic Res 2006;15:455-463.