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Volumn 13, Issue 1, 2015, Pages 71-88

Caffeine: Cognitive and physical performance enhancer or psychoactive drug?

Author keywords

Abuse; Caffeine; Coffee; Dependence; Energy drinks; Safety doses; Toxicity

Indexed keywords

5 ACETAMIDO 6 FORMYLAMINO 3 METHYLURACIL; ADENOSINE A1 RECEPTOR; ADENOSINE A2A RECEPTOR; ADENOSINE A2B RECEPTOR; ADENOSINE RECEPTOR BLOCKING AGENT; CAFFEINE; CALCIUM; CYCLIC GMP; CYCLOOXYGENASE 2; CYTOCHROME P450 1A2; ENDOTHELIAL NITRIC OXIDE SYNTHASE; HORMONE SENSITIVE LIPASE; PARAXANTHINE; PHOSPHODIESTERASE; PSYCHOTROPIC AGENT; CENTRAL STIMULANT AGENT; NOOTROPIC AGENT;

EID: 84929320352     PISSN: 1570159X     EISSN: 18756190     Source Type: Journal    
DOI: 10.2174/1570159X13666141210215655     Document Type: Article
Times cited : (364)

References (190)
  • 1
    • 33645880779 scopus 로고    scopus 로고
    • Rx: Caffeine
    • Lee, R.A.; Balick, M.J. Rx: Caffeine. Explore (NY), 2006, 2(1), 55- 59. http://dx.doi.org/10.1016/j.explore.2005.10.012
    • (2006) Explore (NY) , vol.2 , Issue.1 , pp. 55-59
    • Lee, R.A.1    Balick, M.J.2
  • 4
    • 58849083195 scopus 로고    scopus 로고
    • Midlife coffee and tea drinking and the risk of latelife dementia: A population-based CAIDE study
    • Eskelinen, M.H.; Ngandu, T.; Tuomilehto, J.; Soininen, H.; Kivipelto, M. Midlife coffee and tea drinking and the risk of latelife dementia: a population-based CAIDE study. J. Alzheimers Dis., 2009, 16, 85-91. DOI: 10.3233/JAD-2009-0920
    • (2009) J. Alzheimers Dis , vol.16 , pp. 85-91
    • Eskelinen, M.H.1    Ngandu, T.2    Tuomilehto, J.3    Soininen, H.4    Kivipelto, M.5
  • 5
    • 84874311332 scopus 로고    scopus 로고
    • Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia
    • Espinosa, J.; Rocha, A.; Nunes, F.; Costa, M.S.; Schein, V.; Kazlauckas, V.; Kalinine, E.; Souza, D.O.; Cunha, R.A.; Porciúncula, L.O. Caffeine consumption prevents memory impairment, neuronal damage, and adenosine A2A receptors upregulation in the hippocampus of a rat model of sporadic dementia. J. Alzheimers Dis., 2013, 34, 509-518. DOI: 10.3233/JAD-111982
    • (2013) J. Alzheimers Dis , vol.34 , pp. 509-518
    • Espinosa, J.1    Rocha, A.2    Nunes, F.3    Costa, M.S.4    Schein, V.5    Kazlauckas, V.6    Kalinine, E.7    Souza, D.O.8    Cunha, R.A.9    Porciúncula, L.O.10
  • 6
    • 33751427701 scopus 로고    scopus 로고
    • Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice
    • Dall'Igna, O.P.; Fett, P.; Gomes, M.W.; Souza, D.O.; Cunha, R.A.; Lara, D.R. Caffeine and adenosine A(2a) receptor antagonists prevent beta-amyloid (25-35)-induced cognitive deficits in mice. Exp. Neurol., 2007, 203, 241-245. http://dx.doi.org/10.1016/j. expneurol.2006.08.008
    • (2007) Exp. Neurol , vol.203 , pp. 241-245
    • Dall'Igna, O.P.1    Fett, P.2    Gomes, M.W.3    Souza, D.O.4    Cunha, R.A.5    Lara, D.R.6
  • 7
    • 77954537925 scopus 로고    scopus 로고
    • Chronic caffeine consumption prevents memory disturbance in different animal models of memory decline
    • Cunha, R.A.; Agostinho, P.M. Chronic caffeine consumption prevents memory disturbance in different animal models of memory decline. J. Alzheimers Dis., 2010, 20 (Suppl 1), 95-116. 10.3233/JAD-2010-1408
    • (2010) J. Alzheimers Dis , vol.20 , pp. 95-116
    • Cunha, R.A.1    Agostinho, P.M.2
  • 8
    • 84872292704 scopus 로고    scopus 로고
    • Caffeine as an attention enhancer: Reviewing existing assumptions
    • Einöther, S.J.; Giesbrecht, T. Caffeine as an attention enhancer: reviewing existing assumptions. Psychopharmacology (Berl), 2013, 225(2), 251-274. http://dx.doi.org/10.1007/s00213-012-2917-4
    • (2013) Psychopharmacology (Berl) , vol.225 , Issue.2 , pp. 251-274
    • Einöther, S.J.1    Giesbrecht, T.2
  • 9
    • 84877104302 scopus 로고    scopus 로고
    • Faster but not smarter: Effects of caffeine and caffeine withdrawal on alertness and performance
    • Rogers, P.J.; Heatherley, S.V.; Mullings, E.L.; Smith, J.E. Faster but not smarter: effects of caffeine and caffeine withdrawal on alertness and performance. Psychopharmacology (Berl), 2013, 226(2), 229-240. http://dx.doi.org/10.1007/s00213-012-2889-4
    • (2013) Psychopharmacology (Berl) , vol.226 , Issue.2 , pp. 229-240
    • Rogers, P.J.1    Heatherley, S.V.2    Mullings, E.L.3    Smith, J.E.4
  • 10
    • 0000729091 scopus 로고    scopus 로고
    • Caffeine reinforcement, discrimination, tolerance, and physical dependence in laboratory animals and humans
    • Schuster, C.R., Kuhar, M.J., Eds.; Springer-Verlag: Heidelberg
    • Griffiths, R.R.; Mumford, G.K. Caffeine reinforcement, discrimination, tolerance, and physical dependence in laboratory animals and humans. In: Handbook of Experimental Pharmacology; Schuster, C.R., Kuhar, M.J., Eds.; Springer-Verlag: Heidelberg, 1996, pp. 315-341. http://dx.doi.org/10.1007/978-3-642-60963-3_9
    • (1996) Handbook of Experimental Pharmacology , pp. 315-341
    • Griffiths, R.R.1    Mumford, G.K.2
  • 12
    • 54349106751 scopus 로고    scopus 로고
    • Caffeine protects against MPTP induced blood-brain barrier dysfunction in mouse striatum
    • Chen, X.; Lan, X.; Roche, I.; Liu, R.; Geiger, J.D. Caffeine protects against MPTP induced blood-brain barrier dysfunction in mouse striatum. J. Neurochem., 2008, 107(4), 1147-1157.
    • (2008) J. Neurochem , vol.107 , Issue.4 , pp. 1147-1157
    • Chen, X.1    Lan, X.2    Roche, I.3    Liu, R.4    Geiger, J.D.5
  • 14
    • 84988258241 scopus 로고    scopus 로고
    • Another Reason to Have a Second Cup of Coffee?. Available at: http://www.cancer.org/cancer/news/expertvoices/post/2011/05/25/a nother-reason-to-have-a-second-cup-of-coffee.aspx. Accessed July 20, 2014.
  • 15
    • 5044229722 scopus 로고    scopus 로고
    • Coffee, decaffeinated coffee, tea and cancer of the colon and rectum: A review of epidemiological studies, 1990-2003
    • Tavani, A.; LaVecchia, C. Coffee, decaffeinated coffee, tea and cancer of the colon and rectum: a review of epidemiological studies, 1990-2003. Cancer Causes Control., 2004, 15(8), 743-757. http://dx.doi.org/10.1023/b:caco.0000043415.28319.c1
    • (2004) Cancer Causes Control , vol.15 , Issue.8 , pp. 743-757
    • Tavani, A.1    LaVecchia, C.2
  • 16
    • 84988258235 scopus 로고    scopus 로고
    • Green Tea. Available at: http://www.cancer.org/treatment/ treatmentsandsideeffects/complementaryandalternativemedicine/he rbsvitaminsandminerals/green-tea. Accessed July 20, 2014.
  • 17
    • 0002681630 scopus 로고
    • Metabolism of caffeine and other components of coffee
    • Garattini, S., Ed.; Raven Press: New York
    • Arnaud, M.J. Metabolism of caffeine and other components of coffee. In: Caffeine, coffee and health; Garattini, S., Ed.; Raven Press: New York, 1993, pp. 43-95.
    • (1993) Caffeine, coffee and health , pp. 43-95
    • Arnaud, M.J.1
  • 18
    • 0345561561 scopus 로고    scopus 로고
    • Actions of caffeine in the brain with special reference to factors that contribute to its widespread use
    • PubMed ID: 10049999
    • Fredholm, B.B.; Bättig, K.; Holmén, J.; Nehlig, A.; Zvartau, E.E. Actions of caffeine in the brain with special reference to factors that contribute to its widespread use. Pharmacol. Rev., 1999, 51(1), 83-133. PubMed ID: 10049999
    • (1999) Pharmacol. Rev , vol.51 , Issue.1 , pp. 83-133
    • Fredholm, B.B.1    Bättig, K.2    Holmén, J.3    Nehlig, A.4    Zvartau, E.E.5
  • 19
    • 0017750420 scopus 로고
    • Caffeine: Its direct and indirect influence on reproduction
    • PubMed ID: 197235
    • Weathersbee, P.S.; Lodge, J.R. Caffeine: Its direct and indirect influence on reproduction. J. Reprod. Med., 1977, 19(2), 55-63. PubMed ID: 197235
    • (1977) J. Reprod. Med , vol.19 , Issue.2 , pp. 55-63
    • Weathersbee, P.S.1    Lodge, J.R.2
  • 20
    • 0032032553 scopus 로고    scopus 로고
    • Rate of caffeine metabolism and risk of spontaneous abortion
    • Fenster, L.; Quale, C.; Hiatt, R.A.; Wilson, M.; Windham, G.C.; Benowitz, N.L. Rate of caffeine metabolism and risk of spontaneous abortion. Am. J. Epidemiol., 1998, 147(5), 503-510. http://dx.doi. org/10.1093/oxfordjournals.aje.a009477
    • (1998) Am. J. Epidemiol , vol.147 , Issue.5 , pp. 503-510
    • Fenster, L.1    Quale, C.2    Hiatt, R.A.3    Wilson, M.4    Windham, G.C.5    Benowitz, N.L.6
  • 21
    • 0002424855 scopus 로고
    • Mechanism of action of caffeine
    • Garattini, S., Ed.; Raven Press: New York
    • Daly, J. Mechanism of action of caffeine. In: Caffeine, Coffee, and Health; Garattini, S., Ed.; Raven Press: New York, 1993, pp. 97- 149.
    • (1993) Caffeine, Coffee, and Health; , pp. 97-149
    • Daly, J.1
  • 22
    • 0025272754 scopus 로고
    • Clinical pharmacology of caffeine
    • Benowitz, N.L. Clinical pharmacology of caffeine. Annu. Rev. Med., 1990, 41, 277-278. http://dx.doi.org/10.1146/annurev.me.41. 020190.001425
    • (1990) Annu. Rev. Med , vol.41 , pp. 277-278
    • Benowitz, N.L.1
  • 23
    • 23044447908 scopus 로고    scopus 로고
    • Methylated purines in urinary stones
    • Safranow, K.; Machoy, Z. Methylated purines in urinary stones. Clinical Chem., 2005, 51(8), 1493-1498. http://dx.doi.org/10.1373/ clinchem.2005.048033
    • (2005) Clinical Chem , vol.51 , Issue.8 , pp. 1493-1498
    • Safranow, K.1    Machoy, Z.2
  • 24
    • 0036711386 scopus 로고    scopus 로고
    • Update on Caffeine consumption, disposition and action
    • Mandel, H.G. Update on Caffeine consumption, disposition and action. Food Chem. Toxicol., 2002, 40(9), 1231-1234. http://dx.doi. org/10.1016/s0278-6915(02)00093-5
    • (2002) Food Chem. Toxicol , vol.40 , Issue.9 , pp. 1231-1234
    • Mandel, H.G.1
  • 25
    • 0033604590 scopus 로고    scopus 로고
    • Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion
    • Klebanoff, M.A.; Levine, R.J.; Dersimonian, R.; Clemens, J.D.; Wilkins, D.G. Maternal serum paraxanthine, a caffeine metabolite, and the risk of spontaneous abortion. New Engl. J. Med., 1999, 341 (22), 1639-1644. http://dx.doi.org/10.1056/nejm199911253412202
    • (1999) New Engl. J. Med , vol.341 , Issue.22 , pp. 1639-1644
    • Klebanoff, M.A.1    Levine, R.J.2    Dersimonian, R.3    Clemens, J.D.4    Wilkins, D.G.5
  • 26
    • 0025969276 scopus 로고
    • Caffeine as a metabolic probe: Exploration of the enzyme-inducing effect of cigarette smoking
    • Kalow, W.; Tang, B.K. Caffeine as a metabolic probe: exploration of the enzyme-inducing effect of cigarette smoking. Clin. Pharmacol. Ther., 1991, 49(1), 44-48. http://dx.doi.org/10.1038/ clpt.1991.8
    • (1991) Clin. Pharmacol. Ther , vol.49 , Issue.1 , pp. 44-48
    • Kalow, W.1    Tang, B.K.2
  • 27
    • 0031421684 scopus 로고    scopus 로고
    • Recent advances in caffeine and theobromine toxicities: A review
    • Eteng, M.U.; Eyong, E.U.; Akpanyung, E.O.; Agiang, M.A.; Aremu, C.Y. Recent advances in caffeine and theobromine toxicities: a review. Plant Foods Hum. Nutr., 1997, 51(3), 231-243. http://dx. doi.org/10.1023/a:1007976831684
    • (1997) Plant Foods Hum. Nutr , vol.51 , Issue.3 , pp. 231-243
    • Eteng, M.U.1    Eyong, E.U.2    Akpanyung, E.O.3    Agiang, M.A.4    Aremu, C.Y.5
  • 28
    • 0020620052 scopus 로고
    • Theobromine kinetics and metabolic disposition
    • Tarka, S.M. Jr.; Arnaud, M.J.; Dvorchik, B.H.; Vesell, E.S. Theobromine kinetics and metabolic disposition. Clin. Pharmacol. Ther., 1983, 34(4), 546-555. http://dx.doi.org/10.1038/clpt.1983.212
    • (1983) Clin. Pharmacol. Ther , vol.34 , Issue.4 , pp. 546-555
    • Tarka, S.M.1    Arnaud, M.J.2    Dvorchik, B.H.3    Vesell, E.S.4
  • 29
    • 0021961266 scopus 로고
    • High levels of methylxanthines in chocolate do not alter theobromine disposition
    • Shively, C.A.; Tarka, S.M. Jr.; Arnaud, M.J.; Dvorchik, B.H.; Passananti, G.T.; Vesell, E.S. High levels of methylxanthines in chocolate do not alter theobromine disposition. Clin. Pharmacol. Ther., 1985, 37(4), 415-424. http://dx.doi.org/10.1038/clpt.1985. 65
    • (1985) Clin. Pharmacol. Ther , vol.37 , Issue.4 , pp. 415-424
    • Shively, C.A.1    Tarka, S.M.2    Arnaud, M.J.3    Dvorchik, B.H.4    Passananti, G.T.5    Vesell, E.S.6
  • 30
    • 0029974530 scopus 로고    scopus 로고
    • Caffeine urinary metabolite ratios as markers of enzyme activity: A theoretical assessment
    • Rostami-Hodjegan, A.; Nurminen, S.; Jackson, P.R.; Tucker, G.T. Caffeine urinary metabolite ratios as markers of enzyme activity: a theoretical assessment. Pharmacogenetics, 1996, 6(2), 121-149. http://dx.doi.org/10.1097/00008571-199604000-00001
    • (1996) Pharmacogenetics , vol.6 , Issue.2 , pp. 121-149
    • Rostami-Hodjegan, A.1    Nurminen, S.2    Jackson, P.R.3    Tucker, G.T.4
  • 31
    • 0023025836 scopus 로고
    • Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man
    • Lelo, A.; Birkett, D.J.; Robson, R.A.; Miners, J.O. Comparative pharmacokinetics of caffeine and its primary demethylated metabolites paraxanthine, theobromine and theophylline in man. Br. J. Clin. Pharmacol., 1986, 22(2), 177-182. http://dx.doi.org/10. 1111/j.1365-2125.1986.tb05246.x
    • (1986) Br. J. Clin. Pharmacol , vol.22 , Issue.2 , pp. 177-182
    • Lelo, A.1    Birkett, D.J.2    Robson, R.A.3    Miners, J.O.4
  • 32
    • 0022340155 scopus 로고
    • Comparison of theophylline and theobromine metabolism in man
    • PubMed ID: 2867879
    • Birkett, D.J.; Dahlquist, R.; Miners, J.O.; Lelo, A.; Billing, B. Comparison of theophylline and theobromine metabolism in man. Drug. Metab. Dispos., 1985, 13(6), 725-728. PubMed ID: 2867879
    • (1985) Drug. Metab. Dispos , vol.13 , Issue.6 , pp. 725-728
    • Birkett, D.J.1    Dahlquist, R.2    Miners, J.O.3    Lelo, A.4    Billing, B.5
  • 33
    • 0033030476 scopus 로고    scopus 로고
    • Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism
    • Gates, S.; Miners, J.O. Cytochrome P450 isoform selectivity in human hepatic theobromine metabolism. Br. J. Clin. Pharmacol., 1999, 47(3), 299-305. http://dx.doi.org/10.1046/j.1365-2125.1999. 00890.x
    • (1999) Br. J. Clin. Pharmacol , vol.47 , Issue.3 , pp. 299-305
    • Gates, S.1    Miners, J.O.2
  • 34
    • 0023778594 scopus 로고
    • Methylxanthines: Toxicity to humans. 1. Theophylline
    • Stavric, B. Methylxanthines: toxicity to humans. 1. Theophylline. Food Chem. Toxic., 1988, 26(6), 541-565. http://dx.doi.org/ 10.1016/0278-6915(88)90007-5
    • (1988) Food Chem. Toxic , vol.26 , Issue.6 , pp. 541-565
    • Stavric, B.1
  • 35
    • 0019631881 scopus 로고
    • The disposition of caffeine during and after pregnancy
    • PubMed ID: 7302604
    • Aldridge, A.; Bailey, J.; Neims, A.H. The disposition of caffeine during and after pregnancy. Semin. Perinatol., 1981, 5(4), 31-34. PubMed ID: 7302604
    • (1981) Semin. Perinatol , vol.5 , Issue.4 , pp. 31-34
    • Aldridge, A.1    Bailey, J.2    Neims, A.H.3
  • 36
    • 0018098415 scopus 로고
    • Effect of smoking on caffeine clearance
    • PubMed ID: 657717
    • Parsons, W.D.; Neims, A.H. Effect of smoking on caffeine clearance. Clin. Pharmacol. Ther., 1978, 24(1), 40-45. PubMed ID: 657717
    • (1978) Clin. Pharmacol. Ther , vol.24 , Issue.1 , pp. 40-45
    • Parsons, W.D.1    Neims, A.H.2
  • 37
    • 0023876246 scopus 로고
    • Changes in rate and pattern of caffeine metabolism after cigarette abstinence
    • Brown, C.R.; Jacob, P. 3rd.; Wilson, M.; Benowitz, N.L. Changes in rate and pattern of caffeine metabolism after cigarette abstinence. Clin. Pharmacol. Ther., 1988, 43(5), 488-491. . http://dx.doi.org/ 10.1038/clpt.1988.63
    • (1988) Clin. Pharmacol. Ther , vol.43 , Issue.5 , pp. 488-491
    • Brown, C.R.1    Jacob, P.2    Wilson, M.3    Benowitz, N.L.4
  • 38
    • 0029847578 scopus 로고    scopus 로고
    • Relation of caffeine intake and blood caffeine concentrations during pregnancy to fetal growth: Prospective population based study
    • Cook, D.G.; Peacock, J.L.; Feyerabend, C.; Carey, I.M.; Jarvis, M.J.; Anderson, H.R.; Bland, J.M. Relation of caffeine intake and blood caffeine concentrations during pregnancy to fetal growth: prospective population based study. BMJ., 1996, 313(7069), 1358- 1362. http://dx.doi.org/10.1136/bmj.313.7069.1358
    • (1996) BMJ , vol.313 , Issue.7069 , pp. 1358-1362
    • Cook, D.G.1    Peacock, J.L.2    Feyerabend, C.3    Carey, I.M.4    Jarvis, M.J.5    Anderson, H.R.6    Bland, J.M.7
  • 39
    • 0032929010 scopus 로고    scopus 로고
    • Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: Effect on the CYP1A2 inducibility in humans
    • Nakajima, M.; Yokoi, T.; Mizutani, M.; Kinoshita, M.; Funayama, M.; Kamataki, T. Genetic polymorphism in the 5'-flanking region of human CYP1A2 gene: effect on the CYP1A2 inducibility in humans. J. Biochem., 1999, 125(4), 803-808. http://dx.doi.org/ 10.1093/oxfordjournals.jbchem.a022352
    • (1999) J. Biochem , vol.125 , Issue.4 , pp. 803-808
    • Nakajima, M.1    Yokoi, T.2    Mizutani, M.3    Kinoshita, M.4    Funayama, M.5    Kamataki, T.6
  • 40
    • 0025967401 scopus 로고
    • Role of adenosine receptors in caffeine tolerance
    • PubMed ID: 1846425
    • Holtzman, S.G.; Mante, S.; Minneman, K.P. Role of adenosine receptors in caffeine tolerance. J. Pharmacol. Exp. Ther. 1991, 256(1), 62-68. PubMed ID: 1846425
    • (1991) J. Pharmacol. Exp. Ther , vol.256 , Issue.1 , pp. 62-68
    • Holtzman, S.G.1    Mante, S.2    Minneman, K.P.3
  • 42
    • 0030861647 scopus 로고    scopus 로고
    • Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia
    • Ferré, S.; Fredholm, B.B.; Morelli, M.; Popoli, P.; Fuxe, K. Adenosine-dopamine receptor-receptor interactions as an integrative mechanism in the basal ganglia. Trends Neurosci., 1997, 20(10), 482-487. http://dx.doi.org/10.1016/s0166-2236(97)01096-5
    • (1997) Trends Neurosci , vol.20 , Issue.10 , pp. 482-487
    • Ferré, S.1    Fredholm, B.B.2    Morelli, M.3    Popoli, P.4    Fuxe, K.5
  • 43
    • 0023196702 scopus 로고
    • Evidence for an antagonism between caffeine and adenosine in the human cardiovascular system
    • Smits, P.; Boekema, P.; De Abreu, R.; Thien, T.; van 't Laar, A. Evidence for an antagonism between caffeine and adenosine in the human cardiovascular system. J. Cardiovasc. Pharmacol., 1987, 10(2), 136-143. http://dx.doi.org/10.1097/00005344-198708000- 00002
    • (1987) J. Cardiovasc. Pharmacol , vol.10 , Issue.2 , pp. 136-143
    • Smits, P.1    Boekema, P.2    De Abreu, R.3    Thien, T.4    van 't Laar, A.5
  • 44
    • 0025016510 scopus 로고
    • Caffeine and human cerebral blood flow: A positron emission tomography study
    • Cameron, O.G.; Modell, J.G.; Hariharan, M. Caffeine and human cerebral blood flow: a positron emission tomography study. Life Sci., 1990, 47(13), 1141-1146.
    • (1990) Life Sci , vol.47 , Issue.13 , pp. 1141-1146
    • Cameron, O.G.1    Modell, J.G.2    Hariharan, M.3
  • 46
    • 0023413016 scopus 로고
    • The distribution of adenosine A1 receptors and 5'-nucleotidase in the brain of some commonly used experimental animals
    • Fastbom, J.; Pazos, A.; Palacios, J. M. The distribution of adenosine A1 receptors and 5'-nucleotidase in the brain of some commonly used experimental animals. Neuroscience, 1987, 22(3), 813-826. http://dx.doi.org/10.1016/0306-4522(87)92961-7
    • (1987) Neuroscience , vol.22 , Issue.3 , pp. 813-826
    • Fastbom, J.1    Pazos, A.2    Palacios, J.M.3
  • 47
    • 0020355715 scopus 로고
    • Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine
    • Goodman, R.R.; Synder, S.H. Autoradiographic localization of adenosine receptors in rat brain using [3H]cyclohexyladenosine. J. Neurosci., 1982, 2(9), 1230-1241.
    • (1982) J. Neurosci , vol.2 , Issue.9 , pp. 1230-1241
    • Goodman, R.R.1    Synder, S.H.2
  • 48
    • 0033562590 scopus 로고    scopus 로고
    • The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions
    • PubMed ID: 10234030
    • Svenningsson, P.; Nomikos, G.G.; Fredholm, B.B. The stimulatory action and the development of tolerance to caffeine is associated with alterations in gene expression in specific brain regions. J. Neurosci., 1999, 19(10), 4011-4022. PubMed ID: 10234030
    • (1999) J. Neurosci , vol.19 , Issue.10 , pp. 4011-4022
    • Svenningsson, P.1    Nomikos, G.G.2    Fredholm, B.B.3
  • 49
    • 0030610486 scopus 로고    scopus 로고
    • Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens
    • Svenningsson, P.; Nomikos, G.G.; Ongini, E.; Fredholm, B.B. Antagonism of adenosine A2A receptors underlies the behavioural activating effect of caffeine and is associated with reduced expression of messenger RNA for NGFI-A and NGFI-B in caudate-putamen and nucleus accumbens. Neuroscience, 1997, 79(3), 753-764. http://dx.doi.org/10.1016/s0306-4522(97)00046-8
    • (1997) Neuroscience , vol.79 , Issue.3 , pp. 753-764
    • Svenningsson, P.1    Nomikos, G.G.2    Ongini, E.3    Fredholm, B.B.4
  • 50
    • 0021193086 scopus 로고
    • The effects of caffeine and theophylline on diaphragm contractility
    • PubMed ID: 6476593
    • Supinski, G.S.; Deal, E.C. Jr.; Kelsen, S.G. The effects of caffeine and theophylline on diaphragm contractility. Am. Rev. Respir. Dis, 1984, 130(3), 429-433. PubMed ID: 6476593
    • (1984) Am. Rev. Respir. Dis , vol.130 , Issue.3 , pp. 429-433
    • Supinski, G.S.1    Deal, E.C.2    Kelsen, S.G.3
  • 51
    • 0017364364 scopus 로고
    • Calcium release from the sarcoplasmic reticulum
    • Endo, M. Calcium release from the sarcoplasmic reticulum. Physiol. Rev., 1977, 57(1), 71-108.
    • (1977) Physiol. Rev , vol.57 , Issue.1 , pp. 71-108
    • Endo, M.1
  • 52
    • 57649198280 scopus 로고    scopus 로고
    • Effect of caffeine on the neuromuscular system-potential as an ergogenic aid
    • Tarnopolsky, M.A. Effect of caffeine on the neuromuscular system-potential as an ergogenic aid. Appl. Physiol. Nutr. Metab., 2008, 33(6), 1284-1289. http://dx.doi.org/10.1139/h08-121
    • (2008) Appl. Physiol. Nutr. Metab , vol.33 , Issue.6 , pp. 1284-1289
    • Tarnopolsky, M.A.1
  • 54
    • 77957559714 scopus 로고    scopus 로고
    • Methylxanthines and the kidney
    • Osswald, H.; Schnermann, J. Methylxanthines and the kidney. Handb. Exp. Pharmacol., 2011, 200, 391-412. http://dx.doi.org/10. 1007/978-3-642-13443-2_15
    • (2011) Handb. Exp. Pharmacol , vol.200 , pp. 391-412
    • Osswald, H.1    Schnermann, J.2
  • 56
    • 0028850952 scopus 로고
    • Effects of epinephrine infusion on muscle glycogenolysis during intense aerobic exercise
    • PubMed ID: 7840170
    • Chesley, A.; Hultman, E.; Spriet, L.L. Effects of epinephrine infusion on muscle glycogenolysis during intense aerobic exercise. Am. J. Physiol. 1995, 268 (1 Pt 1), 127-134. PubMed ID: 7840170
    • (1995) Am. J. Physiol , vol.268 , Issue.1 , pp. 127-134
    • Chesley, A.1    Hultman, E.2    Spriet, L.L.3
  • 57
    • 0034854986 scopus 로고    scopus 로고
    • Caffeine and exercise: Metabolism, endurance and performance
    • Graham, T.E. Caffeine and exercise: metabolism, endurance and performance. Sports Med., 2001, 31(11), 785-807. http://dx.doi. org/10.2165/00007256-200131110-00002
    • (2001) Sports Med , vol.31 , Issue.11 , pp. 785-807
    • Graham, T.E.1
  • 58
    • 80053326413 scopus 로고    scopus 로고
    • The effect of adding caffeine to postexercise carbohydrate feeding on subsequent high-intensity interval-running capacity compared with carbohydrate alone
    • PubMed ID: 21832305
    • Taylor, C.; Higham, D.; Close, G.L; Morton, J.P. The effect of adding caffeine to postexercise carbohydrate feeding on subsequent high-intensity interval-running capacity compared with carbohydrate alone. Int. J. Sport. Nutr. Exerc. Metab., 2011, 21(5), 410-416. PubMed ID: 21832305
    • (2011) Int. J. Sport. Nutr. Exerc. Metab , vol.21 , Issue.5 , pp. 410-416
    • Taylor, C.1    Higham, D.2    Close, G.L.3    Morton, J.P.4
  • 59
    • 1342304175 scopus 로고    scopus 로고
    • Caffeine ingestion does not impede the resynthesis of proglycogen and macroglycogen after prolonged exercise and carbohydrate supplementation in humans
    • (1985)
    • Battram, D.S.; Shearer, J.; Robinson, D.; Graham, T.E. Caffeine ingestion does not impede the resynthesis of proglycogen and macroglycogen after prolonged exercise and carbohydrate supplementation in humans. J. Appl. Physiol. (1985), 2004, 96(3), 943-950. http://dx.doi.org/10.1152/japplphysiol.00745.2003
    • (2004) J. Appl. Physiol , vol.96 , Issue.3 , pp. 943-950
    • Battram, D.S.1    Shearer, J.2    Robinson, D.3    Graham, T.E.4
  • 60
    • 50649083512 scopus 로고    scopus 로고
    • High rates of muscle glycogen resynthesis after exhaustive exercise when carbohydrate is coingested with caffeine
    • Pedersen, D.J.; Lessard S.J.; Coffey, V.G.; Churchley, E.G.; Wootton, A,M.; Ng, T.; Watt, M.J.; Hawley, J.A. High rates of muscle glycogen resynthesis after exhaustive exercise when carbohydrate is coingested with caffeine. J. Appl. Physiol. (1985), 2008, 105(1), 7-13. http://dx.doi.org/10.1152/japplphysiol.01121.2007
    • (2008) J. Appl. Physiol. (1985) , vol.105 , Issue.1 , pp. 7-13
    • Pedersen, D.J.1    Lessard, S.J.2    Coffey, V.G.3    Churchley, E.G.4    Wootton, A.M.5    Ng, T.6    Watt, M.J.7    Hawley, J.A.8
  • 61
    • 0026683177 scopus 로고
    • Caffeine ingestion and muscle metabolism during prolonged exercise in humans
    • PubMed ID: 1616022
    • Spriet, L.L.; MacLean, D.A.; Dyck, D.J.; Hultman, E.; Cederblad, G.; Graham, T.E. Caffeine ingestion and muscle metabolism during prolonged exercise in humans. Am. J. Physiol., 1992, 262 (6 Pt 1), 891-898. PubMed ID: 1616022
    • (1992) Am. J. Physiol , vol.262 , Issue.6 , pp. 891-898
    • Spriet, L.L.1    MacLean, D.A.2    Dyck, D.J.3    Hultman, E.4    Cederblad, G.5    Graham, T.E.6
  • 62
    • 0034751819 scopus 로고    scopus 로고
    • Skeletal muscle glycogen phosphorylase a kinetics: Effects of adenine nucleotides and caffeine
    • PubMed ID: 11641346
    • Rush, J.W.; Spriet, L.L. Skeletal muscle glycogen phosphorylase a kinetics: effects of adenine nucleotides and caffeine. J. Appl. Physiol. (1985), 2001, 91(5), 2071-2078. PubMed ID: 11641346
    • (2001) J. Appl. Physiol. (1985) , vol.91 , Issue.5 , pp. 2071-2078
    • Rush, J.W.1    Spriet, L.L.2
  • 63
    • 77649209068 scopus 로고    scopus 로고
    • A case of fatal caffeine poisoning
    • Rudolph, T.; Knudsen, K. A case of fatal caffeine poisoning. Acta Anaesthesiol. Scand., 2010, 54(4), 521-523. http://dx.doi.org/10. 1111/j.1399-6576.2009.02201.x
    • (2010) Acta Anaesthesiol. Scand , vol.54 , Issue.4 , pp. 521-523
    • Rudolph, T.1    Knudsen, K.2
  • 64
    • 84871055424 scopus 로고    scopus 로고
    • Coffee, caffeine, and risk of hospitalization for arrhythmias
    • Klatsky, A.L.; Hasan, A.S.; Armstrong, M.A.; Udaltsova, N.; Morton, C. Coffee, caffeine, and risk of hospitalization for arrhythmias. Perm. J., 2011, 15(3), 19-25.
    • (2011) Perm. J , vol.15 , Issue.3 , pp. 19-25
    • Klatsky, A.L.1    Hasan, A.S.2    Armstrong, M.A.3    Udaltsova, N.4    Morton, C.5
  • 65
    • 0030796601 scopus 로고    scopus 로고
    • Caffeine and cardiac arrhythmias. An experimental study in dogs with review of literature
    • PubMed ID: 9217918
    • Mehta, A.; Jain, A.C.; Mehta, M.C.; Billie, M. Caffeine and cardiac arrhythmias. An experimental study in dogs with review of literature. Acta Cardiol., 1997, 52(3), 273-283. PubMed ID: 9217918
    • (1997) Acta Cardiol , vol.52 , Issue.3 , pp. 273-283
    • Mehta, A.1    Jain, A.C.2    Mehta, M.C.3    Billie, M.4
  • 66
    • 84867894965 scopus 로고    scopus 로고
    • Hypertension in a young boy: An energy drink effect
    • Usman, A.; Jawaid, A. Hypertension in a young boy: an energy drink effect. BMC Res. Notes, 2012, 5, 591.
    • (2012) BMC Res. Notes , vol.5 , pp. 591
    • Usman, A.1    Jawaid, A.2
  • 67
    • 58249104036 scopus 로고    scopus 로고
    • Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks"
    • Berger, A.J.; Alford, K. Cardiac arrest in a young man following excess consumption of caffeinated "energy drinks". Med. J. Aust., 2009, 190(1), 41-43.
    • (2009) Med. J. Aust , vol.190 , Issue.1 , pp. 41-43
    • Berger, A.J.1    Alford, K.2
  • 68
    • 25444525106 scopus 로고    scopus 로고
    • Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis
    • Balasubramaniam, R; Chawla, S.; Grace, A.A.; Huang, C.L. Caffeine-induced arrhythmias in murine hearts parallel changes in cellular Ca(2+) homeostasis. Am. J. Physiol. Heart Circ. Physiol., 2005, 289(4), H1584-1593. http://dx.doi.org/10.1152/ajpheart. 01250.2004
    • (2005) Am. J. Physiol. Heart Circ. Physiol , vol.289 , Issue.4 , pp. H1584-H1593
    • Balasubramaniam, R.1    Chawla, S.2    Grace, A.A.3    Huang, C.L.4
  • 69
    • 79952914102 scopus 로고    scopus 로고
    • Caffeine and Cardiac Arrhythmias: A Review of the Evidence
    • Daniel, J.; Pelchovitz, M.D.; Jeffrey, J.; Goldberger, M.D. Caffeine and Cardiac Arrhythmias: A Review of the Evidence. Am. J. Med., 2011, 124, 284-289. http://dx.doi.org/10.1016/j.amjmed.2010.10.017
    • (2011) Am. J. Med , vol.124 , pp. 284-289
    • Daniel, J.1    Pelchovitz, M.D.2    Jeffrey, J.3    Goldberger, M.D.4
  • 71
    • 0018386393 scopus 로고
    • Electrophysiologic properties of coffee in man
    • Gould, L.; Reddy, C.V.; Oh, K.C.; Kim, S.G.; Becker, W. Electrophysiologic properties of coffee in man. J. Clin. Pharmacol., 1979, 19(1), 46-55. http://dx.doi.org/10.1002/j.1552-4604.1979.tb01616.x
    • (1979) J. Clin. Pharmacol , vol.19 , Issue.1 , pp. 46-55
    • Gould, L.1    Reddy, C.V.2    Oh, K.C.3    Kim, S.G.4    Becker, W.5
  • 72
    • 0020538888 scopus 로고
    • The arrhythmogenic effects of caffeine in human beings
    • Dobmeyer, D.J.; Stine, R.A.; Leier, C.V.; Greenberg, R.; Schaal, S.F. The arrhythmogenic effects of caffeine in human beings. N. Engl. J. Med., 1983, 308(14), 814-816. http://dx.doi.org/10.1056/ nejm198304073081405
    • (1983) N. Engl. J. Med , vol.308 , Issue.14 , pp. 814-816
    • Dobmeyer, D.J.1    Stine, R.A.2    Leier, C.V.3    Greenberg, R.4    Schaal, S.F.5
  • 73
    • 0035064252 scopus 로고    scopus 로고
    • An evaluation of the change in electrocardiographic P-wave variables after acute caffeine ingestion in normal volunteers
    • Caron, M.F.; Song, J.; Ammar, R.; Kluger, J.; White, C.M. An evaluation of the change in electrocardiographic P-wave variables after acute caffeine ingestion in normal volunteers. J. Clin. Pharm. Ther., 2001, 26(2), 145-148.
    • (2001) J. Clin. Pharm. Ther , vol.26 , Issue.2 , pp. 145-148
    • Caron, M.F.1    Song, J.2    Ammar, R.3    Kluger, J.4    White, C.M.5
  • 74
    • 65749087827 scopus 로고    scopus 로고
    • Effect of "energy drink" consumption on hemodynamic and electrocardio graphic parameters in healthy young adults
    • Steinke, L.; Lanfear, D.E.; Dhanapal, V.; Kalus, J.S. Effect of "energy drink" consumption on hemodynamic and electrocardio graphic parameters in healthy young adults. Ann. Pharmacother., 2009, 43(4), 596-602. http://dx.doi.org/10.1345/aph.1l614
    • (2009) Ann. Pharmacother , vol.43 , Issue.4 , pp. 596-602
    • Steinke, L.1    Lanfear, D.E.2    Dhanapal, V.3    Kalus, J.S.4
  • 75
    • 0035072543 scopus 로고    scopus 로고
    • Evaluation of electrocardiographic and hemodynamic effects of caffeine with acute dosing in healthy volunteers
    • Ammar, R.; Song, J.C.; Kluger, J.; White, C.M. Evaluation of electrocardiographic and hemodynamic effects of caffeine with acute dosing in healthy volunteers. Pharmacotherapy., 2001, 21(4), 437-442. http://dx.doi.org/10.1592/phco.21.5.437.34502
    • (2001) Pharmacotherapy , vol.21 , Issue.4 , pp. 437-442
    • Ammar, R.1    Song, J.C.2    Kluger, J.3    White, C.M.4
  • 76
    • 0031728998 scopus 로고    scopus 로고
    • Acute effects of caffeine ingestion on signal-averaged electrocardiograms
    • Donnerstein, R.L.; Zhu, D.; Samson, R.; Bender, A.M.; Goldberg, S.J. Acute effects of caffeine ingestion on signal-averaged electrocardiograms. Am. Heart J., 1998, 136(4 Pt 1), 643-646. http://dx.doi.org/10.1016/s0002-8703(98)70011-0
    • (1998) Am. Heart J , vol.136 , Issue.4 , pp. 643-646
    • Donnerstein, R.L.1    Zhu, D.2    Samson, R.3    Bender, A.M.4    Goldberg, S.J.5
  • 77
    • 0021951359 scopus 로고
    • The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia
    • PubMed ID: 3971755
    • Sutherland, D.J.; McPherson, D.D.; Renton, K.W.; Spencer, C.A.; Montague, T.J. The effect of caffeine on cardiac rate, rhythm, and ventricular repolarization. Analysis of 18 normal subjects and 18 patients with primary ventricular dysrhythmia. Chest., 1985, 87(3), 319-324. PubMed ID: 3971755
    • (1985) Chest , vol.87 , Issue.3 , pp. 319-324
    • Sutherland, D.J.1    McPherson, D.D.2    Renton, K.W.3    Spencer, C.A.4    Montague, T.J.5
  • 78
    • 0025016108 scopus 로고
    • Caffeine and ventricular arrhythmias. An electrophysiological approach
    • Chelsky, L.B.; Cutler, J.E.; Griffith, K.; Kron, J.; McClelland, J.H.; McAnulty, J.H. Caffeine and ventricular arrhythmias. An electrophysiological approach. JAMA., 1990, 264(17), 2236-2240.
    • (1990) JAMA , vol.264 , Issue.17 , pp. 2236-2240
    • Chelsky, L.B.1    Cutler, J.E.2    Griffith, K.3    Kron, J.4    McClelland, J.H.5    McAnulty, J.H.6
  • 79
    • 0029800384 scopus 로고    scopus 로고
    • Metabolic catecholamine, and endurance responses to caffeine during intense exercise
    • PubMed ID: 8904583
    • Jackman, M.; Wendling, P.; Friars, D.; Graham, T.E. Metabolic catecholamine, and endurance responses to caffeine during intense exercise. J. Appl. Physiol., 1996, 81(4), 1658-1663. PubMed ID: 8904583
    • (1996) J. Appl. Physiol , vol.81 , Issue.4 , pp. 1658-1663
    • Jackman, M.1    Wendling, P.2    Friars, D.3    Graham, T.E.4
  • 80
    • 84897874944 scopus 로고    scopus 로고
    • Caffeine intake and atrial fibrillation incidence: Dose response meta-analysis of prospective cohort studies
    • Cheng, M.; Hu, Z.; Lu, X.; Huang, J.; Gu, D. Caffeine intake and atrial fibrillation incidence: dose response meta-analysis of prospective cohort studies. Can. J. Cardiol., 2014, 30(4), 448-454. http://dx.doi.org/10.1016/j.cjca.2013.12.026
    • (2014) Can. J. Cardiol , vol.30 , Issue.4 , pp. 448-454
    • Cheng, M.1    Hu, Z.2    Lu, X.3    Huang, J.4    Gu, D.5
  • 81
    • 0037016061 scopus 로고    scopus 로고
    • Coffee acutely increases sympathetic nerve activity and blood pressure independently of caffeine content: Role of habitual versus nonhabitual drinking
    • Corti, R.; Binggeli, C.; Sudano, I.; Spieker, L.; Hänseler, E.; Ruschitzka, F.; Chaplin, W.F.; Lüscher, T.F.; Noll, G. Coffee acutely increases sympathetic nerve activity and blood pressure independently of caffeine content: role of habitual versus nonhabitual drinking. Circulation, 2002, 106(23), 2935-2940. http://dx.doi.org/10.1161/01.cir.0000046228.97025.3a
    • (2002) Circulation , vol.106 , Issue.23 , pp. 2935-2940
    • Corti, R.1    Binggeli, C.2    Sudano, I.3    Spieker, L.4    Hänseler, E.5    Ruschitzka, F.6    Chaplin, W.F.7    Lüscher, T.F.8    Noll, G.9
  • 82
    • 84867893004 scopus 로고    scopus 로고
    • Elevated pre-operative serum peptides for collagen I and III synthesis result in post-surgical atrial fibrillation
    • Swartz, M.F.; Fink, G.W.; Sarwar, M.F.; Hicks, G.L.; Yu, Y.; Hu, R.; Lutz, C.J.; Taffet, S.M.; Jalife, J. Elevated pre-operative serum peptides for collagen I and III synthesis result in post-surgical atrial fibrillation. J. Am. Coll. Cardiol., 2012, 60(18), 1799-1806. http:// dx.doi.org/10.1016/j.jacc.2012.06.048
    • (2012) J. Am. Coll. Cardiol , vol.60 , Issue.18 , pp. 1799-1806
    • Swartz, M.F.1    Fink, G.W.2    Sarwar, M.F.3    Hicks, G.L.4    Yu, Y.5    Hu, R.6    Lutz, C.J.7    Taffet, S.M.8    Jalife, J.9
  • 84
    • 84880699422 scopus 로고    scopus 로고
    • Coffee attenuates fibrosis by decreasing the expression of TGF-β and CTGF in a murine model of liver damage
    • Arauz, J.; Moreno, M.G.; Cortés-Reynosa, P.; Salazar, E.P.; Muriel, P. Coffee attenuates fibrosis by decreasing the expression of TGF-β and CTGF in a murine model of liver damage. J. Appl. Toxicol., 2013, 33(9), 970-979. http://dx.doi.org/10.1002/jat.2788
    • (2013) J. Appl. Toxicol , vol.33 , Issue.9 , pp. 970-979
    • Arauz, J.1    Moreno, M.G.2    Cortés-Reynosa, P.3    Salazar, E.P.4    Muriel, P.5
  • 86
    • 4444305701 scopus 로고    scopus 로고
    • Coffee drinking is dose-dependently related to the risk of acute coronary events in middle-aged men
    • Happonen, P.; Voutilainen, S.; Salonen, J.T. Coffee drinking is dose-dependently related to the risk of acute coronary events in middle-aged men. J. Nutr., 2004, 134(9), 2381-2386.
    • (2004) J. Nutr , vol.134 , Issue.9 , pp. 2381-2386
    • Happonen, P.1    Voutilainen, S.2    Salonen, J.T.3
  • 87
    • 1842738665 scopus 로고    scopus 로고
    • Cardiovascular effects of caffeine in men and women
    • Hartley, T.R.; Lovallo, W.R.; Whitsett, T.L. Cardiovascular effects of caffeine in men and women. Am. J. Cardiol., 2004, 93(8), 1022- 1026. http://dx.doi.org/10.1016/j.amjcard.2003.12.057
    • (2004) Am. J. Cardiol , vol.93 , Issue.8 , pp. 1022-1026
    • Hartley, T.R.1    Lovallo, W.R.2    Whitsett, T.L.3
  • 88
    • 13244267190 scopus 로고    scopus 로고
    • Association of ambulatory blood pressure and dietary caffeine in adolescents
    • Savoca, M.R.; MacKey, M.L.; Evans, C.D.; Wilson, M.; Ludwig, D.A.; Harshfield, G.A. Association of ambulatory blood pressure and dietary caffeine in adolescents. Am. J. Hypertens., 2005, 18(1), 116-120. http://dx.doi.org/10.1016/j.amjhyper.2004.08.011
    • (2005) Am. J. Hypertens , vol.18 , Issue.1 , pp. 116-120
    • Savoca, M.R.1    MacKey, M.L.2    Evans, C.D.3    Wilson, M.4    Ludwig, D.A.5    Harshfield, G.A.6
  • 90
    • 0021363352 scopus 로고
    • Cardiovascular effects of coffee and caffeine
    • Whitsett, T.L.; Manion, C.V.; Christensen, H.D. Cardiovascular effects of coffee and caffeine. Am. J. Cardiol., 1984, 53(7), 918- 922. http://dx.doi.org/10.1016/0002-9149(84)90525-3
    • (1984) Am. J. Cardiol , vol.53 , Issue.7 , pp. 918-922
    • Whitsett, T.L.1    Manion, C.V.2    Christensen, H.D.3
  • 91
    • 0028867136 scopus 로고
    • Effect of caffeine on myocardial blood flow at rest and during pharmacological vasodilation
    • PubMed ID: 7472591
    • Böttcher, M.; Czernin, J.; Sun, K.T.; Phelps, M.E.; Schelbert, H.R. Effect of caffeine on myocardial blood flow at rest and during pharmacological vasodilation. J. Nucl. Med., 1995, 36(11), 2016- 2021. PubMed ID: 7472591
    • (1995) J. Nucl. Med , vol.36 , Issue.11 , pp. 2016-2021
    • Böttcher, M.1    Czernin, J.2    Sun, K.T.3    Phelps, M.E.4    Schelbert, H.R.5
  • 92
    • 0035570722 scopus 로고    scopus 로고
    • Acute effect of caffeine on arterial stiffness and aortic pressure waveform
    • Mahmud, A.; Feely, J. Acute effect of caffeine on arterial stiffness and aortic pressure waveform. Hypertension, 2001, 38(2), 227-231. http://dx.doi.org/10.1161/01.hyp.38.2.227
    • (2001) Hypertension , vol.38 , Issue.2 , pp. 227-231
    • Mahmud, A.1    Feely, J.2
  • 93
    • 0028790731 scopus 로고
    • Endothelium-dependent and -independent vasodilation of isolated rat aorta induced by caffeine
    • PubMed ID: 7503265
    • Hatano, Y.; Mizumoto, K.; Yoshiyama, T.; Yamamoto, M.; Iranami, H. Endothelium-dependent and -independent vasodilation of isolated rat aorta induced by caffeine. Am. J. Physiol., 1995, 269(5 Pt 2), 1679-1684. PubMed ID: 7503265
    • (1995) Am. J. Physiol , vol.269 , Issue.5 , pp. 1679-1684
    • Hatano, Y.1    Mizumoto, K.2    Yoshiyama, T.3    Yamamoto, M.4    Iranami, H.5
  • 94
    • 84899125377 scopus 로고    scopus 로고
    • Fatal caffeine intoxication: A series of eight cases from 1999 to 2009
    • Banerjee, P.; Ali, Z.; Levine, B.; Fowler, D.R. Fatal caffeine intoxication: a series of eight cases from 1999 to 2009. J. Forensic Sci., 2014, 59(3), 865-868. DOI: 10.1111/1556-4029.12387
    • (2014) J. Forensic Sci , vol.59 , Issue.3 , pp. 865-868
    • Banerjee, P.1    Ali, Z.2    Levine, B.3    Fowler, D.R.4
  • 95
    • 13844256127 scopus 로고    scopus 로고
    • Acute effects of caffeine on blood pressure and wave reflections in healthy subjects: Should we consider monitoring central blood pressure?
    • Karatzis, E.; Papaioannou, T.G.; Aznaouridis, K.; Karatzi, K.; Stamatelopoulos, K.; Zampelas, A.; Papamichael, C.; Lekakis, J.; Mavrikakis, M. Acute effects of caffeine on blood pressure and wave reflections in healthy subjects: should we consider monitoring central blood pressure? Int. J. Cardiol., 2005, 98(3), 425-430. http://dx.doi.org/10.1016/j.ijcard.2003.11.013
    • (2005) Int. J. Cardiol , vol.98 , Issue.3 , pp. 425-430
    • Karatzis, E.1    Papaioannou, T.G.2    Aznaouridis, K.3    Karatzi, K.4    Stamatelopoulos, K.5    Zampelas, A.6    Papamichael, C.7    Lekakis, J.8    Mavrikakis, M.9
  • 96
    • 0031036155 scopus 로고    scopus 로고
    • Myocardial infarction resulting from caffeine overdose in an anorectic woman
    • Forman, J.; Aizer, A.; Young, C.R. Myocardial infarction resulting from caffeine overdose in an anorectic woman. Ann. Emerg. Med., 1997, 29(1), 178-180. http://dx.doi.org/10.1016/s0196-0644(97) 70326-3
    • (1997) Ann. Emerg. Med , vol.29 , Issue.1 , pp. 178-180
    • Forman, J.1    Aizer, A.2    Young, C.R.3
  • 97
    • 84864643535 scopus 로고    scopus 로고
    • A case of caffeine-induced coronary artery vasospasm of a 17-year-old male
    • Wilson, R.E.; Kado, H.S.; Samson, R.; Miller, A.B. A case of caffeine-induced coronary artery vasospasm of a 17-year-old male. Cardiovasc. Toxicol., 2012, 12(2), 175-179. http://dx.doi.org/10. 1007/s12012-011-9152-9
    • (2012) Cardiovasc. Toxicol , vol.12 , Issue.2 , pp. 175-179
    • Wilson, R.E.1    Kado, H.S.2    Samson, R.3    Miller, A.B.4
  • 98
    • 0035111097 scopus 로고    scopus 로고
    • The influence of a taurine containing drink on cardiac parameters before and after exercise measured by echocardiography
    • Baum, M.; Weiss, M. The influence of a taurine containing drink on cardiac parameters before and after exercise measured by echocardiography. Amino Acids, 2001, 20(1), 75-82. http://dx.doi. org/10.1007/s007260170067
    • (2001) Amino Acids , vol.20 , Issue.1 , pp. 75-82
    • Baum, M.1    Weiss, M.2
  • 99
    • 84858694577 scopus 로고    scopus 로고
    • Left main coronary artery acute thrombosis related to energy drink intake
    • Benjo, A.M.; Pineda, A.M.; Nascimento, F.O.; Zamora, C.; Lamas, G.A.; Escolar, E. Left main coronary artery acute thrombosis related to energy drink intake. Circulation, 2012, 125(11), 1447-1448. http://dx.doi.org/10.1161/circulationaha.111.086017
    • (2012) Circulation , vol.125 , Issue.11 , pp. 1447-1448
    • Benjo, A.M.1    Pineda, A.M.2    Nascimento, F.O.3    Zamora, C.4    Lamas, G.A.5    Escolar, E.6
  • 100
    • 74849139629 scopus 로고    scopus 로고
    • Detrimental effects of energy drink consumption on platelet and endothelial function
    • Worthley, M.I.; Prabhu, A.; De Sciscio, P.; Schultz, C.; Sanders, P.; Willoughby, S.R. Detrimental effects of energy drink consumption on platelet and endothelial function. Am. J. Med., 2010, 123(2), 184-187. http://dx.doi.org/10.1016/j.amjmed.2009.09.013
    • (2010) Am. J. Med , vol.123 , Issue.2 , pp. 184-187
    • Worthley, M.I.1    Prabhu, A.2    De Sciscio, P.3    Schultz, C.4    Sanders, P.5    Willoughby, S.R.6
  • 102
    • 66549115700 scopus 로고    scopus 로고
    • Coffee consumption and risk of cardiovascular diseases and allcause mortality among men with type 2 diabetes
    • Zhang, W.; Lopez-Garcia, E.; Li, T.Y.; Hu, F.B.; van Dam, R.M. Coffee consumption and risk of cardiovascular diseases and allcause mortality among men with type 2 diabetes. Diabetes Care, 2009, 32(6), 1043-1045. http://dx.doi.org/10.2337/dc08-2251
    • (2009) Diabetes Care , vol.32 , Issue.6 , pp. 1043-1045
    • Zhang, W.1    Lopez-Garcia, E.2    Li, T.Y.3    Hu, F.B.4    van Dam, R.M.5
  • 103
    • 33646448742 scopus 로고    scopus 로고
    • Coffee consumption and coronary heart disease in men and women: A prospective cohort study
    • Lopez-Garcia, E.; van Dam, R.M.; Willett, W.C.; Rimm, E.B.; Manson, J.E.; Stampfer, M.J.; Rexrode, K.M.; Hu, F.B. Coffee consumption and coronary heart disease in men and women: a prospective cohort study. Circulation, 2006, 113(17), 2045-2053. http://dx.doi.org/10.1161/circulationaha.105.598664
    • (2006) Circulation , vol.113 , Issue.17 , pp. 2045-2053
    • Lopez-Garcia, E.1    van Dam, R.M.2    Willett, W.C.3    Rimm, E.B.4    Manson, J.E.5    Stampfer, M.J.6    Rexrode, K.M.7    Hu, F.B.8
  • 104
    • 0024501913 scopus 로고
    • The effect of caffeine on exercise tolerance and left ventricular function in patients with coronary artery disease
    • PubMed ID: 2930092
    • Hirsch, A.T.; Gervino, E.V.; Nakao, S.; Come, P.C.; Silverman, K.J.; Grossman, W. The effect of caffeine on exercise tolerance and left ventricular function in patients with coronary artery disease. Ann. Intern. Med., 1989, 110(8), 593-598. PubMed ID: 2930092
    • (1989) Ann. Intern. Med , vol.110 , Issue.8 , pp. 593-598
    • Hirsch, A.T.1    Gervino, E.V.2    Nakao, S.3    Come, P.C.4    Silverman, K.J.5    Grossman, W.6
  • 105
    • 33846854890 scopus 로고    scopus 로고
    • Caffeinated beverage intake and the risk of heart disease mortality in the elderly: A prospective analysis
    • PubMed ID: 17284734
    • Greenberg, J.A.; Dunbar, C.C.; Schnoll, R.; Kokolis, R.; Kokolis, S.; Kassotis, J. Caffeinated beverage intake and the risk of heart disease mortality in the elderly: a prospective analysis. Am. J. Clin. Nutr., 2007, 85(2), 392-398. PubMed ID: 17284734
    • (2007) Am. J. Clin. Nutr , vol.85 , Issue.2 , pp. 392-398
    • Greenberg, J.A.1    Dunbar, C.C.2    Schnoll, R.3    Kokolis, R.4    Kokolis, S.5    Kassotis, J.6
  • 106
    • 0020387329 scopus 로고
    • Diet-induced mood changes in normal populations
    • Leathwood, P.D.; Pollet, P. Diet-induced mood changes in normal populations. J. Psychiatr. Res., 1982, 17(2), 147-154.
    • (1982) J. Psychiatr. Res , vol.17 , Issue.2 , pp. 147-154
    • Leathwood, P.D.1    Pollet, P.2
  • 107
    • 0002016436 scopus 로고    scopus 로고
    • Caffeine and cognitive performance: Effects on mood or mental processing
    • Gupta, B.S., Gupta, U., Eds.; CRC Press: Washington
    • Rusted, J. Caffeine and cognitive performance: Effects on mood or mental processing. In: Caffeine and behavior: Current views and research trends; Gupta, B.S., Gupta, U., Eds.; CRC Press: Washington, 1999; pp. 221-229.
    • (1999) Caffeine and behavior: Current views and research trends; , pp. 221-229
    • Rusted, J.1
  • 108
    • 0024535692 scopus 로고
    • Caffeine-induced anxiogenesis: The role of adenosine, benzodiazepine and noradrenergic receptors
    • Baldwin, H.A.; File, S.E. Caffeine-induced anxiogenesis: the role of adenosine, benzodiazepine and noradrenergic receptors. Pharmacol. Biochem. Behav., 1989, 32(1), 181-186. http://dx.doi. org/10.1016/0091-3057(89)90230-x
    • (1989) Pharmacol. Biochem. Behav , vol.32 , Issue.1 , pp. 181-186
    • Baldwin, H.A.1    File, S.E.2
  • 109
    • 0022402068 scopus 로고
    • Caffeine and diazepam: Separate and combined effects on mood, memory, and psychomotor performance
    • Loke, W.H.; Hinrichs, J.V.; Ghoneim, M.M. Caffeine and diazepam: separate and combined effects on mood, memory, and psychomotor performance. Psychopharmacology (Berl), 1985, 87(3), 344-350. http://dx.doi.org/10.1007/bf00432719
    • (1985) Psychopharmacology (Berl) , vol.87 , Issue.3 , pp. 344-350
    • Loke, W.H.1    Hinrichs, J.V.2    Ghoneim, M.M.3
  • 111
    • 77956222203 scopus 로고    scopus 로고
    • Is caffeine a cognitive enhancer?
    • Nehlig, A. Is caffeine a cognitive enhancer? J. Alzheimers Dis., 2010, 20 (Suppl 1), 85-94. http://dx.doi.org/10.1007/s00213-005-0084-6
    • (2010) J. Alzheimers Dis , vol.20 , pp. 85-94
    • Nehlig, A.1
  • 112
    • 25844438929 scopus 로고    scopus 로고
    • Effects of caffeine on performance and mood: Withdrawal reversal is the most plausible explanation
    • James, J.E.; Rogers, P.J. Effects of caffeine on performance and mood: withdrawal reversal is the most plausible explanation. Psychopharmacology (Berl), 2005, 182(1), 1-8. http://dx.doi.org/ 10.1007/s00213-005-0084-6
    • (2005) Psychopharmacology (Berl) , vol.182 , Issue.1 , pp. 1-8
    • James, J.E.1    Rogers, P.J.2
  • 113
    • 0027396728 scopus 로고
    • Does caffeine intake enhance absolute levels of cognitive performance?
    • Jarvis, M.J. Does caffeine intake enhance absolute levels of cognitive performance? Psychopharmacology (Berl), 1993, 110(1-2), 45-52. http://dx.doi.org/10.1007/bf02246949
    • (1993) Psychopharmacology (Berl) , vol.110 , Issue.1-2 , pp. 45-52
    • Jarvis, M.J.1
  • 115
    • 0030827837 scopus 로고    scopus 로고
    • Anxiogenic action of caffeine: An experimental study in rats
    • Bhattacharya, S.K.; Satyan, K.S.; Chakrabarti, A. Anxiogenic action of caffeine: an experimental study in rats. J. Psychopharmacol., 1997, 11(3), 219-224. http://dx.doi.org/10.1177/026988119701100304
    • (1997) J. Psychopharmacol , vol.11 , Issue.3 , pp. 219-224
    • Bhattacharya, S.K.1    Satyan, K.S.2    Chakrabarti, A.3
  • 116
    • 0009267815 scopus 로고    scopus 로고
    • The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists
    • El Yacoubi, M.; Ledent, C.; Parmentier, M.; Costentin, J.; Vaugeois, J.M. The anxiogenic-like effect of caffeine in two experimental procedures measuring anxiety in the mouse is not shared by selective A(2A) adenosine receptor antagonists. Psychopharmacology (Berl), 2000, 148(2), 153-163. http://dx.doi.org/ 10.1007/s002130050037
    • (2000) Psychopharmacology (Berl) , vol.148 , Issue.2 , pp. 153-163
    • El Yacoubi, M.1    Ledent, C.2    Parmentier, M.3    Costentin, J.4    Vaugeois, J.M.5
  • 117
    • 0020446391 scopus 로고
    • Caffeine and human behavior: Arousal, anxiety, and performance effects
    • Sawyer, D.A.; Julia, H.L.; Turin, A.C. Caffeine and human behavior: arousal, anxiety, and performance effects. J. Behav. Med., 1982, 5(4), 415-439. http://dx.doi.org/10.1007/bf00845371
    • (1982) J. Behav. Med , vol.5 , Issue.4 , pp. 415-439
    • Sawyer, D.A.1    Julia, H.L.2    Turin, A.C.3
  • 118
    • 77954763359 scopus 로고    scopus 로고
    • Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption
    • Rogers, P.J.; Hohoff, C.; Heatherley, S.V.; Mullings, E.L.; Maxfield, P.J.; Evershed, R.P.; Deckert, J.; Nutt, D.J. Association of the anxiogenic and alerting effects of caffeine with ADORA2A and ADORA1 polymorphisms and habitual level of caffeine consumption. Neuropsychopharmacology, 2010, 35(9), 1973-1983.
    • (2010) Neuropsychopharmacology , vol.35 , Issue.9 , pp. 1973-1983
    • Rogers, P.J.1    Hohoff, C.2    Heatherley, S.V.3    Mullings, E.L.4    Maxfield, P.J.5    Evershed, R.P.6    Deckert, J.7    Nutt, D.J.8
  • 119
    • 79955701624 scopus 로고    scopus 로고
    • Acute and adaptive motor responses to caffeine in adolescent and adult rats
    • Rhoads, D.E.; Huggler, A.L.; Rhoads, L. Acute and adaptive motor responses to caffeine in adolescent and adult rats. J. Pharmacol. Biochem. Behav., 2011, 99(1), 81-86. http://dx.doi.org/10.1016/ j.pbb.2011.04.001
    • (2011) J. Pharmacol. Biochem. Behav , vol.99 , Issue.1 , pp. 81-86
    • Rhoads, D.E.1    Huggler, A.L.2    Rhoads, L.3
  • 121
    • 0035754519 scopus 로고    scopus 로고
    • Effect of short-term and chronic caffeine intake on rats with various anxiety level
    • Sudakov, S.K.; Medvedeva, O.F.; Rusakova, I.V.; Figurina, I.B. Effect of short-term and chronic caffeine intake on rats with various anxiety level. Bull. Exp. Biol. Med., 2001, 132(6), 1177- 1179. http://dx.doi.org/10.1023/a:1014511415473
    • (2001) Bull. Exp. Biol. Med , vol.132 , Issue.6 , pp. 1177-1179
    • Sudakov, S.K.1    Medvedeva, O.F.2    Rusakova, I.V.3    Figurina, I.B.4
  • 122
    • 0036046427 scopus 로고    scopus 로고
    • Does caffeine intake protect from Alzheimer's disease?
    • Maia, L.; de Mendonça, A. Does caffeine intake protect from Alzheimer's disease? Eur. J. Neurol., 2002, 9(4), 377-382. http:// dx.doi.org/10.1046/j.1468-1331.2002.00421.x
    • (2002) Eur. J. Neurol , vol.9 , Issue.4 , pp. 377-382
    • Maia, L.1    de Mendonça, A.2
  • 123
  • 124
    • 8444243293 scopus 로고    scopus 로고
    • Protective effect of caffeine against neurodegeneration in a model of Parkinson's disease in rat: Behavioral and histochemical evidence
    • Joghataie, M.T.; Roghani, M.; Negahdar, F.; Hashemi, L. Protective effect of caffeine against neurodegeneration in a model of Parkinson's disease in rat: behavioral and histochemical evidence. Parkinsonism Relat. Disord., 2004, 10(8), 465-468. http://dx.doi.org/10.1016/j.parkreldis.2004.06.004
    • (2004) Parkinsonism Relat. Disord , vol.10 , Issue.8 , pp. 465-468
    • Joghataie, M.T.1    Roghani, M.2    Negahdar, F.3    Hashemi, L.4
  • 125
    • 77957258032 scopus 로고    scopus 로고
    • Caffeine-Not just a stimulant
    • Glade, M.J. Caffeine-Not just a stimulant. Nutrition, 2010, 26(10), 932-938. http://dx.doi.org/10.1016/j.nut.2010.08.004
    • (2010) Nutrition , vol.26 , Issue.10 , pp. 932-938
    • Glade, M.J.1
  • 126
    • 79955419165 scopus 로고    scopus 로고
    • Effects of caffeine on sleep and cognition
    • Snel, J.; Lorist, M.M. Effects of caffeine on sleep and cognition. Prog. Brain Res., 2011, 190, 105-117.
    • (2011) Prog. Brain Res , vol.190 , pp. 105-117
    • Snel, J.1    Lorist, M.M.2
  • 128
    • 70349309933 scopus 로고    scopus 로고
    • Adenosine receptors and the central nervous system
    • Sebastião, A.M.; Ribeiro, J.A. Adenosine receptors and the central nervous system. Handb. Exp. Pharmacol., 2009, 193, 471-534. http://dx.doi.org/10.1007/978-3-540-89615-9_16
    • (2009) Handb. Exp. Pharmacol , vol.193 , pp. 471-534
    • Sebastião, A.M.1    Ribeiro, J.A.2
  • 129
    • 84859560679 scopus 로고    scopus 로고
    • Therapeutic potential of A2 and A3 adenosine receptor: A review of novel patented ligands
    • Federico, S.; Spalluto, G. Therapeutic potential of A2 and A3 adenosine receptor: a review of novel patented ligands. Expert Opin. Ther. Pat., 2012, 22(4), 369-390. http://dx.doi.org/10.1517/ 13543776.2012.669375
    • (2012) Expert Opin. Ther. Pat , vol.22 , Issue.4 , pp. 369-390
    • Federico, S.1    Spalluto, G.2
  • 130
    • 77956196113 scopus 로고    scopus 로고
    • Caffeine as a protective factor in dementia and Alzheimer's disease
    • Eskelinen, M.H.; Kivipelto, M. Caffeine as a protective factor in dementia and Alzheimer's disease. J. Alzheimers Dis., 2010, 20, 167-174. DOI: 10.3233/JAD-2010-1404
    • (2010) J. Alzheimers Dis , vol.20 , pp. 167-174
    • Eskelinen, M.H.1    Kivipelto, M.2
  • 131
    • 80053384033 scopus 로고    scopus 로고
    • Differential neuroprotection by A(1) receptor activation and A(2A) receptor inhibition following pilocarpine-induced status epilepticus
    • Rosim, F.E.; Persike, D.S.; Nehlig, A.; Amorim, R.P.; de Oliveira, D.M.; Fernandes, M.J. Differential neuroprotection by A(1) receptor activation and A(2A) receptor inhibition following pilocarpine-induced status epilepticus. Epilepsy Behav., 2011, 22(2), 207-213. http://dx.doi.org/10.1016/j.yebeh.2011.07.004
    • (2011) Epilepsy Behav , vol.22 , Issue.2 , pp. 207-213
    • Rosim, F.E.1    Persike, D.S.2    Nehlig, A.3    Amorim, R.P.4    de Oliveira, D.M.5    Fernandes, M.J.6
  • 132
    • 77953517373 scopus 로고    scopus 로고
    • A1 receptors ligands: Past, present,and future trends
    • Schenone, S.; Brullo, C.; Musumeci, F.; Bruno, O.; Botta, M. A1 receptors ligands: past, present,and future trends. Curr. Top. Med. Chem., 2010, 10(9), 878-901. http://dx.doi.org/10.2174/ 156802610791268729
    • (2010) Curr. Top. Med. Chem , vol.10 , Issue.9 , pp. 878-901
    • Schenone, S.1    Brullo, C.2    Musumeci, F.3    Bruno, O.4    Botta, M.5
  • 133
    • 78650514763 scopus 로고    scopus 로고
    • Deletion of adenosine A₁ or A(₂A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease
    • Xiao, D.; Cassin, J.J.; Healy, B.; Burdett, T.C.; Chen, J.F.; Fredholm, B.B.; Schwarzschild, M.A. Deletion of adenosine A₁ or A(₂A) receptors reduces L-3,4-dihydroxyphenylalanine-induced dyskinesia in a model of Parkinson's disease. Brain Res., 2011, 1367, 310-318. http://dx.doi.org/10.1016/j.brainres.2010.08.099
    • (2011) Brain Res , vol.1367 , pp. 310-318
    • Xiao, D.1    Cassin, J.J.2    Healy, B.3    Burdett, T.C.4    Chen, J.F.5    Fredholm, B.B.6    Schwarzschild, M.A.7
  • 134
    • 3042648309 scopus 로고    scopus 로고
    • Seizures and epilepsy after ischemic stroke
    • Camilo, F.; Goldstein, L.B. Seizures and epilepsy after ischemic stroke. Stroke, 2004, 35(7), 1769-1775. http://dx.doi.org/10.1161/ 01.str.0000130989.17100.96
    • (2004) Stroke , vol.35 , Issue.7 , pp. 1769-1775
    • Camilo, F.1    Goldstein, L.B.2
  • 135
    • 77957600542 scopus 로고    scopus 로고
    • Impacts of methylxanthines and adenosine receptors on neurodegeneration: Human and experimental studies
    • Chen, J.F.; Chern, Y. Impacts of methylxanthines and adenosine receptors on neurodegeneration: human and experimental studies. Handb. Exp. Pharmacol., 2011, 200, 267-310. http://dx.doi.org/10. 1007/978-3-642-13443-2_10
    • (2011) Handb. Exp. Pharmacol , vol.200 , pp. 267-310
    • Chen, J.F.1    Chern, Y.2
  • 136
    • 84901276014 scopus 로고    scopus 로고
    • Alzheimer's silent partner: Cerebral amyloid angiopathy
    • Cupino, T.L.; Zabel, M.K. Alzheimer's silent partner: cerebral amyloid angiopathy. Transl. Stroke Res., 2014, 5(3), 330-337. http://dx.doi.org/10.1007/s12975-013-0309-7
    • (2014) Transl. Stroke Res , vol.5 , Issue.3 , pp. 330-337
    • Cupino, T.L.1    Zabel, M.K.2
  • 137
    • 84878242670 scopus 로고    scopus 로고
    • Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: Relevance and clinical implications
    • Salvemini, D.; Kim, S.F.; Mollace, V. Reciprocal regulation of the nitric oxide and cyclooxygenase pathway in pathophysiology: relevance and clinical implications. Am. J. Physiol. Regul. Integr. Comp. Physiol., 2013, 304(7), 473-487. http://dx.doi.org/10.1152/ ajpregu.00355.2012
    • (2013) Am. J. Physiol. Regul. Integr. Comp. Physiol , vol.304 , Issue.7 , pp. 473-487
    • Salvemini, D.1    Kim, S.F.2    Mollace, V.3
  • 138
    • 84862876684 scopus 로고    scopus 로고
    • Role of secondary mediators in caffeine-mediated neuroprotection in maneb- and paraquat-induced Parkinson's disease phenotype in the mouse
    • Yadav, S.; Gupta, S.P.; Srivastava, G.; Srivastava, P.K.; Singh. M.P. Role of secondary mediators in caffeine-mediated neuroprotection in maneb- and paraquat-induced Parkinson's disease phenotype in the mouse. Neurochem. Res., 2012, 37(4), 875-884. http://dx.doi. org/10.1007/s11064-011-0682-0
    • (2012) Neurochem. Res , vol.37 , Issue.4 , pp. 875-884
    • Yadav, S.1    Gupta, S.P.2    Srivastava, G.3    Srivastava, P.K.4    Singh, M.P.5
  • 139
    • 84865781758 scopus 로고    scopus 로고
    • Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model
    • Chu, Y.F.; Chang, W.H.; Black, R.M.; Liu, J.R.; Sompol, P.; Chen, Y.; Wei, H.; Zhao, Q.; Cheng, I,H. Crude caffeine reduces memory impairment and amyloid β(1-42) levels in an Alzheimer's mouse model. Food Chem., 2012, 135(3), 2095-2102. http://dx.doi.org/10. 1016/j.foodchem.2012.04.148
    • (2012) Food Chem , vol.135 , Issue.3 , pp. 2095-2102
    • Chu, Y.F.1    Chang, W.H.2    Black, R.M.3    Liu, J.R.4    Sompol, P.5    Chen, Y.6    Wei, H.7    Zhao, Q.8    Cheng, I.H.9
  • 140
    • 84866293285 scopus 로고    scopus 로고
    • Caffeine and risk of Parkinson's disease in a large cohort of men and women
    • Palacios, N.; Gao, X.; McCullough, M.L.; Caffeine and risk of Parkinson's disease in a large cohort of men and women. Mov. Disord., 2012, 27(10), 1276-1282. http://dx.doi.org/10.1002/mds.25076
    • (2012) Mov. Disord , vol.27 , Issue.10 , pp. 1276-1282
    • Palacios, N.1    Gao, X.2    McCullough, M.L.3
  • 141
    • 84862821537 scopus 로고    scopus 로고
    • Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease
    • Sonsalla, P.K.; Wong, L.Y.; Harris, S.L. Delayed caffeine treatment prevents nigral dopamine neuron loss in a progressive rat model of Parkinson's disease. Exp. Neurol., 2012, 234(2), 482-487. http://dx.doi.org/10.1016/j.expneurol.2012.01.022
    • (2012) Exp. Neurol , vol.234 , Issue.2 , pp. 482-487
    • Sonsalla, P.K.1    Wong, L.Y.2    Harris, S.L.3
  • 142
    • 77956180469 scopus 로고    scopus 로고
    • Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet
    • Prasanthi, J.R.; Dasari, B.; Marwarha, G. Caffeine protects against oxidative stress and Alzheimer's disease-like pathology in rabbit hippocampus induced by cholesterol-enriched diet. Free Radic. Biol. Med., 2010, 49(7), 1212-1220. http://dx.doi.org/10.1016/ j.freeradbiomed.2010.07.007
    • (2010) Free Radic. Biol. Med , vol.49 , Issue.7 , pp. 1212-1220
    • Prasanthi, J.R.1    Dasari, B.2    Marwarha, G.3
  • 143
    • 77956180419 scopus 로고    scopus 로고
    • Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases
    • Chen, X.; Ghribi, O.; Geiger, J.D. Caffeine protects against disruptions of the blood-brain barrier in animal models of Alzheimer's and Parkinson's diseases. J. Alzheimers Dis., 2010, 20 (Suppl 1), 127-141. DOI: 10.3233/JAD-2010-1376
    • (2010) J. Alzheimers Dis , vol.20 , pp. 127-141
    • Chen, X.1    Ghribi, O.2    Geiger, J.D.3
  • 144
    • 84867526964 scopus 로고    scopus 로고
    • Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells
    • Dragicevic, N.; Delic, V.; Cao, C.; Copes, N.; Lin, X.; Mamcarz, M.; Wang, L.; Arendash, G.W.; Bradshaw, P.C. Caffeine increases mitochondrial function and blocks melatonin signaling to mitochondria in Alzheimer's mice and cells. Neuropharmacology, 2012, 63(8), 1368-1379. http://dx.doi.org/10.1016/j.neuropharm.2012.08.018
    • (2012) Neuropharmacology , vol.63 , Issue.8 , pp. 1368-1379
    • Dragicevic, N.1    Delic, V.2    Cao, C.3    Copes, N.4    Lin, X.5    Mamcarz, M.6    Wang, L.7    Arendash, G.W.8    Bradshaw, P.C.9
  • 145
    • 0028321498 scopus 로고
    • CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil
    • Gao, Y.; Phillis, J.W. CGS 15943, an adenosine A2 receptor antagonist, reduces cerebral ischemic injury in the Mongolian gerbil. Life Sci., 1994, 55(3), 61-65. http://dx.doi.org/10.1016/ 0024-3205(94)00889-2
    • (1994) Life Sci , vol.55 , Issue.3 , pp. 61-65
    • Gao, Y.1    Phillis, J.W.2
  • 146
    • 84944363339 scopus 로고
    • Caffeine as an analgesic adjuvant
    • Laska, E.M.; Sunshine, A.; Mueller, F.; Elvers, W.B.; Siegel, C.; Rubin, A. Caffeine as an analgesic adjuvant. JAMA, 1984, 251(13), 1711-1718. http://dx.doi.org/10.1001/jama.251.13.1711
    • (1984) JAMA , vol.251 , Issue.13 , pp. 1711-1718
    • Laska, E.M.1    Sunshine, A.2    Mueller, F.3    Elvers, W.B.4    Siegel, C.5    Rubin, A.6
  • 147
    • 0033834590 scopus 로고    scopus 로고
    • Ibuprofen plus caffeine in the treatment of tension-type headache
    • Diamond, S.; Balm, T.K.; Freitag, F.G. Ibuprofen plus caffeine in the treatment of tension-type headache. Clin. Pharmacol. Ther., 2000, 68(3), 312-319. http://dx.doi.org/10.1067/mcp.2000.109353
    • (2000) Clin. Pharmacol. Ther , vol.68 , Issue.3 , pp. 312-319
    • Diamond, S.1    Balm, T.K.2    Freitag, F.G.3
  • 148
    • 0025980362 scopus 로고
    • The analgesic effects of caffeine in headache
    • Ward, N.; Whitney, C.; Avery, D.; Dunner, D. The analgesic effects of caffeine in headache. Pain, 1991, 44(2), 151-155. http:// dx.doi.org/10.1016/0304-3959(91)90129-l
    • (1991) Pain , vol.44 , Issue.2 , pp. 151-155
    • Ward, N.1    Whitney, C.2    Avery, D.3    Dunner, D.4
  • 149
    • 0032939786 scopus 로고    scopus 로고
    • Intravenous administration of caffeine sodium benzoate for postdural puncture headache
    • Yücel, A.; Ozyalçin, S.; Talu, G.K.; Yücel, E.C.; Erdine, S. Intravenous administration of caffeine sodium benzoate for postdural puncture headache. Reg. Anesth. Pain Med., 1999, 24(1), 51-54. http://dx.doi.org/10.1097/00115550-199924010-00010
    • (1999) Reg. Anesth. Pain Med , vol.24 , Issue.1 , pp. 51-54
    • Yücel, A.1    Ozyalçin, S.2    Talu, G.K.3    Yücel, E.C.4    Erdine, S.5
  • 150
    • 13844272137 scopus 로고    scopus 로고
    • Oral multidose caffeineparacetamol combination is not effective for the prophylaxis of postdural puncture headache
    • Esmaoglu, A.; Akpinar, H.; Uğur, F. Oral multidose caffeineparacetamol combination is not effective for the prophylaxis of postdural puncture headache. J. Clin. Anesth., 2005, 17(1), 58-61. http://dx.doi.org/10.1016/j.jclinane.2004.04.003
    • (2005) J. Clin. Anesth , vol.17 , Issue.1 , pp. 58-61
    • Esmaoglu, A.1    Akpinar, H.2    Uğur, F.3
  • 151
    • 58149184515 scopus 로고    scopus 로고
    • Caffeine and headaches
    • Shapiro, R.E. Caffeine and headaches. Curr. Pain Headache Rep., 2008, 12(4), 311-315. http://dx.doi.org/10.1007/s11916-008-0052-z
    • (2008) Curr. Pain Headache Rep , vol.12 , Issue.4 , pp. 311-315
    • Shapiro, R.E.1
  • 152
    • 0023841493 scopus 로고
    • Caffeine physical dependence: A review of human and laboratory animal studies
    • Griffiths, R.R.; Woodson, P.P. Caffeine physical dependence: a review of human and laboratory animal studies. Psychopharmacology (Berl), 1988, 94(4), 437-451. http://dx.doi.org/10.1007/bf00212836
    • (1988) Psychopharmacology (Berl) , vol.94 , Issue.4 , pp. 437-451
    • Griffiths, R.R.1    Woodson, P.P.2
  • 154
    • 25844513494 scopus 로고    scopus 로고
    • Caffeine stimulation of cortisol secretion across the waking hours in relation to caffeine intake levels
    • Lovallo, W.R.; Whitsett, T.L.; al'Absi, M.; Sung, B.H.; Vincent, A.S.; Wilson, M.F. Caffeine stimulation of cortisol secretion across the waking hours in relation to caffeine intake levels. Psychosom. Med., 2005, 67(5), 734-739. DOI: 10.1097/01.psy.0000181270. 20036.06
    • (2005) Psychosom. Med , vol.67 , Issue.5 , pp. 734-739
    • Lovallo, W.R.1    Whitsett, T.L.2    al'Absi, M.3    Sung, B.H.4    Vincent, A.S.5    Wilson, M.F.6
  • 156
    • 0742270588 scopus 로고    scopus 로고
    • Critical review of dietary caffeine and blood pressure: A relationship that should be taken more seriously
    • James, J.E. Critical review of dietary caffeine and blood pressure: a relationship that should be taken more seriously. Psychosom. Med., 2004, 66(1), 63-71. http://dx.doi.org/10.1097/10.psy.0000107884. 78247.f9
    • (2004) Psychosom. Med , vol.66 , Issue.1 , pp. 63-71
    • James, J.E.1
  • 157
    • 1642460659 scopus 로고    scopus 로고
    • Blood pressure response to caffeine shows incomplete tolerance after short-term regular consumption
    • Lovallo, W.R.; Wilson, M.F.; Vincent, A.S.; Sung, B.H.; McKey, B.S.; Whitsett, T.L. Blood pressure response to caffeine shows incomplete tolerance after short-term regular consumption. Hypertension, 2004, 43(4), 760-765. http://dx.doi.org/10.1161/ 01.hyp.0000120965.63962.93
    • (2004) Hypertension , vol.43 , Issue.4 , pp. 760-765
    • Lovallo, W.R.1    Wilson, M.F.2    Vincent, A.S.3    Sung, B.H.4    McKey, B.S.5    Whitsett, T.L.6
  • 158
    • 84988307247 scopus 로고
    • Looking for the Perfect Brew
    • Eisenberg, S. Looking for the Perfect Brew. Sci. News, 1988, 133, 252-253.
    • (1988) Sci. News , vol.133 , pp. 252-253
    • Eisenberg, S.1
  • 161
    • 0024331057 scopus 로고
    • Hooked on hormones? An anabolic steroid addiction hypothesis
    • Kashkin, K.B.; Kleber, H.D. Hooked on hormones? An anabolic steroid addiction hypothesis. JAMA, 1989, 262(22), 3166-3170.
    • (1989) JAMA , vol.262 , Issue.22 , pp. 3166-3170
    • Kashkin, K.B.1    Kleber, H.D.2
  • 162
    • 84988272664 scopus 로고    scopus 로고
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition-Text Revision (DSMIV- TR); APA: Washington, 2000.
  • 163
    • 84988294530 scopus 로고    scopus 로고
    • American Psychiatric Association. Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5); APA: Arlington, 2013.
  • 164
    • 84988272662 scopus 로고    scopus 로고
    • WHO. Lexicon of alcohol and drug terms. World Health Organization: Geneva, 1995.
  • 165
    • 0032905099 scopus 로고    scopus 로고
    • A three-pathway psychobiological model of craving for alcohol
    • Verheul, R.; van den Brink, W.; Geerlings, P. A three-pathway psychobiological model of craving for alcohol. Alcohol Alcohol., 1999, 34(2), 197-222.
    • (1999) Alcohol Alcohol , vol.34 , Issue.2 , pp. 197-222
    • Verheul, R.1    van den Brink, W.2    Geerlings, P.3
  • 166
    • 84988277283 scopus 로고    scopus 로고
    • World Health Organization. The ICD-10 classification of mental and behavioural disorders: clinical descriptions and diagnostic guidelines; World Health Organization: Geneva, 1992.
  • 167
    • 0016278372 scopus 로고
    • Anxiety or caffeinism: A diagnostic dilemma
    • Greden, J.F. Anxiety or caffeinism: a diagnostic dilemma. Am. J. Psychiatry, 1974, 131(10), 1089-1092.
    • (1974) Am. J. Psychiatry , vol.131 , Issue.10 , pp. 1089-1092
    • Greden, J.F.1
  • 169
    • 33644631621 scopus 로고    scopus 로고
    • Coffee and health: A review of recent human research
    • Higdon, J.V.; Frei, B. Coffee and health: a review of recent human research. Crit. Rev. Food Sci. Nutr., 2006, 46(2), 101-123. http://dx.doi.org/10.1080/10408390500400009
    • (2006) Crit. Rev. Food Sci. Nutr , vol.46 , Issue.2 , pp. 101-123
    • Higdon, J.V.1    Frei, B.2
  • 171
    • 0016218385 scopus 로고
    • Lethal caffeine poisoning in a child
    • Dimaio, V.J.; Garriott, J.C. Lethal caffeine poisoning in a child. Forensic Sci., 1974, 3(3), 275-278. http://dx.doi.org/10.1016/0300- 9432(74)90056-9
    • (1974) Forensic Sci , vol.3 , Issue.3 , pp. 275-278
    • Dimaio, V.J.1    Garriott, J.C.2
  • 172
    • 0017736270 scopus 로고
    • A fatal ingestion of caffeine
    • Turner, J.E.; Cravey, R.H. A fatal ingestion of caffeine. Clin. Toxicol., 1977, 10(3), 341-344. http://dx.doi.org/10.3109/ 15563657708992428
    • (1977) Clin. Toxicol , vol.10 , Issue.3 , pp. 341-344
    • Turner, J.E.1    Cravey, R.H.2
  • 173
    • 0018831149 scopus 로고
    • Caffeine poisoning in a 19-year-old female
    • PubMed ID: 7391779
    • McGee, M.B. Caffeine poisoning in a 19-year-old female. J. Forensic Sci., 1980, 25(1), 29-32. PubMed ID: 7391779
    • (1980) J. Forensic Sci , vol.25 , Issue.1 , pp. 29-32
    • McGee, M.B.1
  • 174
    • 0019780959 scopus 로고
    • Suicide by ingestion of caffeine
    • PubMed ID: 6895464
    • Bryant, J. Suicide by ingestion of caffeine. Arch. Pathol. Lab. Med., 1981, 105(12), 685-686. PubMed ID: 6895464
    • (1981) Arch. Pathol. Lab. Med , vol.105 , Issue.12 , pp. 685-686
    • Bryant, J.1
  • 175
    • 0021078742 scopus 로고
    • A multi-chemical death involving caffeine, nicotine and malathion
    • Chaturvedi, A.K.; Rao, N.G.; McCoy, F.E. A multi-chemical death involving caffeine, nicotine and malathion. Forensic Sci. Int., 1983, 23(2-3), 265-275. http://dx.doi.org/10.1016/0379-0738(83)90155-x
    • (1983) Forensic Sci. Int , vol.23 , Issue.2-3 , pp. 265-275
    • Chaturvedi, A.K.1    Rao, N.G.2    McCoy, F.E.3
  • 176
    • 0021997768 scopus 로고
    • Five cases of fatal overdose from caffeine-containing "look-alike" drugs
    • Garriott, J.C.; Simmons, L.M.; Poklis, A.; Mackell, M.A. Five cases of fatal overdose from caffeine-containing "look-alike" drugs. J. Anal. Toxicol., 1985, 9(3), 141-143. http://dx.doi.org/10. 1093/jat/9.3.141
    • (1985) J. Anal. Toxicol , vol.9 , Issue.3 , pp. 141-143
    • Garriott, J.C.1    Simmons, L.M.2    Poklis, A.3    Mackell, M.A.4
  • 178
    • 0023619619 scopus 로고
    • Caffeine toxicity: A case of child abuse by drug ingestion
    • PubMed ID: 3323412
    • Morrow, P.L. Caffeine toxicity: a case of child abuse by drug ingestion. J. Forensic Sci., 1987, 32(6), 1801-1805. PubMed ID: 3323412
    • (1987) J. Forensic Sci , vol.32 , Issue.6 , pp. 1801-1805
    • Morrow, P.L.1
  • 179
    • 0024847191 scopus 로고
    • Massive caffeine ingestion resulting in death
    • PubMed ID: 2617841
    • Mrvos, R.M.; Reilly, P.E.; Dean, B.S.; Krenzelok, E.P. Massive caffeine ingestion resulting in death. Vet. Hum. Toxicol., 1989, 31(6), 571-572. PubMed ID: 2617841
    • (1989) Vet. Hum. Toxicol , vol.31 , Issue.6 , pp. 571-572
    • Mrvos, R.M.1    Reilly, P.E.2    Dean, B.S.3    Krenzelok, E.P.4
  • 181
    • 0346365539 scopus 로고    scopus 로고
    • Caffeine fatalities-four case reports
    • Holmgren, P.; Nordén-Pettersson, L.; Ahlner, J. Caffeine fatalities-four case reports. Forensic Sci. In., 2004, 139(1), 71-73. http://dx. doi.org/10.1016/j.forsciint.2003.09.019
    • (2004) Forensic Sci. In , vol.139 , Issue.1 , pp. 71-73
    • Holmgren, P.1    Nordén-Pettersson, L.2    Ahlner, J.3
  • 182
    • 22444448412 scopus 로고    scopus 로고
    • Fatal caffeine overdose: Two case reports
    • Kerrigan, S.; Lindsey, T. Fatal caffeine overdose: two case reports. Forensic Sci. Int., 2005, 153(1), 67-69. http://dx.doi.org/10.1016/ j.forsciint.2005.04.016
    • (2005) Forensic Sci. Int , vol.153 , Issue.1 , pp. 67-69
    • Kerrigan, S.1    Lindsey, T.2
  • 184
    • 84892812514 scopus 로고    scopus 로고
    • Fatal Ceffeine overdose: A case report and review of literature
    • Jabbar, S.B.; Hanly, M.G. Fatal Ceffeine overdose: a case report and review of literature. Am. J. Forensic Med. Pathol., 2013, 34(4), 321-324. http://dx.doi.org/10.1097/paf.0000000000000058
    • (2013) Am. J. Forensic Med. Pathol , vol.34 , Issue.4 , pp. 321-324
    • Jabbar, S.B.1    Hanly, M.G.2
  • 185
    • 84886101245 scopus 로고    scopus 로고
    • A fatal case involving a caffeine-containing fat burner
    • Jantos, R.; Stein, K.M.; Flechtenmacher, C.; Skopp, G. A fatal case involving a caffeine-containing fat burner. Drug Test. Anal., 2013, 5(9-10), 773-776. http://dx.doi.org/10.1002/dta.1485
    • (2013) Drug Test. Anal , vol.5 , Issue.9-10 , pp. 773-776
    • Jantos, R.1    Stein, K.M.2    Flechtenmacher, C.3    Skopp, G.4
  • 188
    • 0035986288 scopus 로고    scopus 로고
    • Caffeine use and dependence in adolescents: One-year follow-up
    • Oberstar, J.V.; Bernstein, G.A.; Thuras, P.D. Caffeine use and dependence in adolescents: one-year follow-up. J. Child Adolesc. Psychopharmacol., 2002, 12(2), 127-135. http://dx.doi.org/10.1089/ 104454602760219162
    • (2002) J. Child Adolesc. Psychopharmacol , vol.12 , Issue.2 , pp. 127-135
    • Oberstar, J.V.1    Bernstein, G.A.2    Thuras, P.D.3
  • 189
    • 0028108535 scopus 로고
    • Caffeine dependence syndrome. Evidence from case histories and experimental evaluations
    • Strain, E.C.; Mumford, G.K.; Silverman, K.; Griffiths, R.R. Caffeine dependence syndrome. Evidence from case histories and experimental evaluations. JAMA, 1994, 272(13), 1043-1048. http://dx.doi.org/10.1001/jama.272.13.1043
    • (1994) JAMA , vol.272 , Issue.13 , pp. 1043-1048
    • Strain, E.C.1    Mumford, G.K.2    Silverman, K.3    Griffiths, R.R.4
  • 190
    • 28444451913 scopus 로고    scopus 로고
    • Caffeine dependence in combination with a family history of alcoholism as a predictor of continued use of caffeine during pregnancy
    • Svikis, D.S.; Berger, N.; Haug, N.A.; Griffiths, R.R. Caffeine dependence in combination with a family history of alcoholism as a predictor of continued use of caffeine during pregnancy. Am. J. Psychiatry, 2005, 162(12), 2344-2351. http://dx.doi.org/10.1176/ appi.ajp.162.12.2344
    • (2005) Am. J. Psychiatry , vol.162 , Issue.12 , pp. 2344-2351
    • Svikis, D.S.1    Berger, N.2    Haug, N.A.3    Griffiths, R.R.4


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