메뉴 건너뛰기




Volumn 100, Issue 5, 2015, Pages E688-E696

Variation in glucose homeostasis traits associated with P2RX7 polymorphisms in mice and humans

Author keywords

[No Author keywords available]

Indexed keywords

GLUCOSE; INSULIN; GLUCOSE BLOOD LEVEL; P2RX7 PROTEIN, HUMAN; P2RX7 PROTEIN, MOUSE; PURINERGIC P2X7 RECEPTOR;

EID: 84929302596     PISSN: 0021972X     EISSN: 19457197     Source Type: Journal    
DOI: 10.1210/jc.2014-4160     Document Type: Article
Times cited : (29)

References (40)
  • 1
    • 84868337361 scopus 로고    scopus 로고
    • Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes
    • Morris AP, Voight BF, Teslovich TM, et al. Large-scale association analysis provides insights into the genetic architecture and pathophysiology of type 2 diabetes. Nat Genet. 2012;44(9):981-990.
    • (2012) Nat Genet , vol.44 , Issue.9 , pp. 981-990
    • Morris, A.P.1    Voight, B.F.2    Teslovich, T.M.3
  • 2
    • 0034744764 scopus 로고    scopus 로고
    • Adenosine 5ô-triphosphate: A P2-purinergic agonist in the myocardium
    • Vassort G. Adenosine 5ô-triphosphate: a P2-purinergic agonist in the myocardium. Physiol Rev. 2001;81(2):767-806.
    • (2001) Physiol Rev , vol.81 , Issue.2 , pp. 767-806
    • Vassort, G.1
  • 3
    • 33746701380 scopus 로고    scopus 로고
    • P2X receptors as cell-surface ATP sensors in health and disease
    • Khakh BS, North RA. P2X receptors as cell-surface ATP sensors in health and disease. Nature. 2006;442(7102):527-532.
    • (2006) Nature , vol.442 , Issue.7102 , pp. 527-532
    • Khakh, B.S.1    North, R.A.2
  • 5
    • 33747423674 scopus 로고    scopus 로고
    • Purinergic signalling - An overview
    • discussion 48-57, 275-281
    • Burnstock G. Purinergic signalling-an overview. Novartis Found Symp. 2006;276:26-48; discussion 48-57, 275-281.
    • (2006) Novartis Found Symp , vol.276 , pp. 26-48
    • Burnstock, G.1
  • 6
    • 33644607461 scopus 로고    scopus 로고
    • Pathophysiology and therapeutic potential of purinergic signaling
    • Burnstock G. Pathophysiology and therapeutic potential of purinergic signaling. Pharmacol Rev. 2006;58(1):58-86.
    • (2006) Pharmacol Rev , vol.58 , Issue.1 , pp. 58-86
    • Burnstock, G.1
  • 7
    • 33846436678 scopus 로고    scopus 로고
    • The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance
    • Robson SC, Sevigny J, Zimmermann H. The E-NTPDase family of ectonucleotidases: Structure function relationships and pathophysiological significance. Purinergic Signal. 2006;2(2):409-430.
    • (2006) Purinergic Signal , vol.2 , Issue.2 , pp. 409-430
    • Robson, S.C.1    Sevigny, J.2    Zimmermann, H.3
  • 8
    • 16344393581 scopus 로고    scopus 로고
    • The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice
    • Leon C, Freund M, Latchoumanin O, et al. The P2Y(1) receptor is involved in the maintenance of glucose homeostasis and in insulin secretion in mice. Purinergic Signal. 2005;1(2):145-151.
    • (2005) Purinergic Signal , vol.1 , Issue.2 , pp. 145-151
    • Leon, C.1    Freund, M.2    Latchoumanin, O.3
  • 9
    • 67650659532 scopus 로고    scopus 로고
    • Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and β cell function and survival
    • Glas R, Sauter NS, Schulthess FT, Shu L, Oberholzer J, Maedler K. Purinergic P2X7 receptors regulate secretion of interleukin-1 receptor antagonist and β cell function and survival. Diabetologia. 2009; 52(8):1579-1588.
    • (2009) Diabetologia , vol.52 , Issue.8 , pp. 1579-1588
    • Glas, R.1    Sauter, N.S.2    Schulthess, F.T.3    Shu, L.4    Oberholzer, J.5    Maedler, K.6
  • 10
    • 62649114002 scopus 로고    scopus 로고
    • P2 purinergic signalling in the pancreatic β-cell: Control of insulin secretion and pharmacology
    • Petit P, Lajoix AD, Gross R. P2 purinergic signalling in the pancreatic β-cell: control of insulin secretion and pharmacology. Eur J Pharmaceut Sci. 2009;37(2):67-75.
    • (2009) Eur J Pharmaceut Sci , vol.37 , Issue.2 , pp. 67-75
    • Petit, P.1    Lajoix, A.D.2    Gross, R.3
  • 11
    • 77950885567 scopus 로고    scopus 로고
    • ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell
    • Jacques-Silva MC, Correa-Medina M, Cabrera O, et al. ATP-gated P2X3 receptors constitute a positive autocrine signal for insulin release in the human pancreatic β cell. Proc Natl Acad Sci USA. 2010;107(14):6465-6470.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.14 , pp. 6465-6470
    • Jacques-Silva, M.C.1    Correa-Medina, M.2    Cabrera, O.3
  • 12
    • 75749086085 scopus 로고    scopus 로고
    • New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
    • Dupuis J, Langenberg C, Prokopenko I, et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk. Nat Genet. 2010;42(2):105-116.
    • (2010) Nat Genet , vol.42 , Issue.2 , pp. 105-116
    • Dupuis, J.1    Langenberg, C.2    Prokopenko, I.3
  • 13
    • 84862785585 scopus 로고    scopus 로고
    • Large-scale gene-centric metaanalysis across 39 studies identifies type 2 diabetes loci
    • Saxena R, Elbers CC, Guo Y, et al. Large-scale gene-centric metaanalysis across 39 studies identifies type 2 diabetes loci. Am J Hum Genet. 2012;90(3):410-425.
    • (2012) Am J Hum Genet , vol.90 , Issue.3 , pp. 410-425
    • Saxena, R.1    Elbers, C.C.2    Guo, Y.3
  • 14
    • 80053405321 scopus 로고    scopus 로고
    • Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes
    • Strawbridge RJ, Dupuis J, Prokopenko I, et al. Genome-wide association identifies nine common variants associated with fasting proinsulin levels and provides new insights into the pathophysiology of type 2 diabetes. Diabetes. 2011;60:2624-2634.
    • (2011) Diabetes , vol.60 , pp. 2624-2634
    • Strawbridge, R.J.1    Dupuis, J.2    Prokopenko, I.3
  • 15
    • 1842539516 scopus 로고    scopus 로고
    • A simple correction for multiple testing for SNPs in linkage disequilibrium with each other
    • Nyholt DR. A simple correction for multiple testing for SNPs in linkage disequilibrium with each other. Am J Hum Genet. 2004; 74(4):765-769.
    • (2004) Am J Hum Genet , vol.74 , Issue.4 , pp. 765-769
    • Nyholt, D.R.1
  • 16
    • 30744434862 scopus 로고    scopus 로고
    • Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix
    • Li J, Ji L. Adjusting multiple testing in multilocus analyses using the eigenvalues of a correlation matrix. Heredity. 2005;95(3):221-227.
    • (2005) Heredity , vol.95 , Issue.3 , pp. 221-227
    • Li, J.1    Ji, L.2
  • 17
    • 77955515264 scopus 로고    scopus 로고
    • A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
    • Isomaa B, Forsen B, Lahti K, et al. A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study. Diabetologia. 2010; 53(8):1709-1713.
    • (2010) Diabetologia , vol.53 , Issue.8 , pp. 1709-1713
    • Isomaa, B.1    Forsen, B.2    Lahti, K.3
  • 18
    • 0037108511 scopus 로고    scopus 로고
    • Cutting edge: A natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor
    • Adriouch S, Dox C, Welge V, Seman M, Koch-Nolte F, Haag F. Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor. J Immunol. 2002; 169(8):4108-4112.
    • (2002) J Immunol , vol.169 , Issue.8 , pp. 4108-4112
    • Adriouch, S.1    Dox, C.2    Welge, V.3    Seman, M.4    Koch-Nolte, F.5    Haag, F.6
  • 20
    • 9644260361 scopus 로고    scopus 로고
    • Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice
    • Almind K, Kahn CR. Genetic determinants of energy expenditure and insulin resistance in diet-induced obesity in mice. Diabetes. 2004;53(12):3274-3285.
    • (2004) Diabetes , vol.53 , Issue.12 , pp. 3274-3285
    • Almind, K.1    Kahn, C.R.2
  • 21
    • 2342423633 scopus 로고    scopus 로고
    • The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes
    • Le Stunff H, Auger R, Kanellopoulos J, Raymond MN. The Pro-451 to Leu polymorphism within the C-terminal tail of P2X7 receptor impairs cell death but not phospholipase D activation in murine thymocytes. J Biol Chem. 2004;279(17):16918-16926.
    • (2004) J Biol Chem , vol.279 , Issue.17 , pp. 16918-16926
    • Le Stunff, H.1    Auger, R.2    Kanellopoulos, J.3    Raymond, M.N.4
  • 22
    • 77955776526 scopus 로고    scopus 로고
    • Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1βsecretion
    • Stokes L, Fuller SJ, Sluyter R, Skarratt KK, Gu BJ, Wiley JS. Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1βsecretion. FASEB J. 2010;24(8):2916-2927.
    • (2010) FASEB J , vol.24 , Issue.8 , pp. 2916-2927
    • Stokes, L.1    Fuller, S.J.2    Sluyter, R.3    Skarratt, K.K.4    Gu, B.J.5    Wiley, J.S.6
  • 23
    • 33646924818 scopus 로고    scopus 로고
    • Human P2X7 pore function predicts allele linkage disequilibrium
    • Denlinger LC, Coursin DB, Schell K, et al. Human P2X7 pore function predicts allele linkage disequilibrium. Clin Chem. 2006;52(6): 995-1004.
    • (2006) Clin Chem , vol.52 , Issue.6 , pp. 995-1004
    • Denlinger, L.C.1    Coursin, D.B.2    Schell, K.3
  • 25
    • 84877728324 scopus 로고    scopus 로고
    • Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4
    • Ma RC, Hu C, Tam CH, et al. Genome-wide association study in a Chinese population identifies a susceptibility locus for type 2 diabetes at 7q32 near PAX4. Diabetologia. 2013;56(6):1291-1305.
    • (2013) Diabetologia , vol.56 , Issue.6 , pp. 1291-1305
    • Ma, R.C.1    Hu, C.2    Tam, C.H.3
  • 26
    • 70349956433 scopus 로고    scopus 로고
    • Finding the missing heritability of complex diseases
    • Manolio TA, Collins FS, Cox NJ, et al. Finding the missing heritability of complex diseases. Nature. 2009;461(7265):747-753.
    • (2009) Nature , vol.461 , Issue.7265 , pp. 747-753
    • Manolio, T.A.1    Collins, F.S.2    Cox, N.J.3
  • 27
    • 43249125992 scopus 로고    scopus 로고
    • Estimation of the multiple testing burden for genomewide association studies of nearly all common variants
    • Pe'er I, Yelensky R, Altshuler D, Daly MJ. Estimation of the multiple testing burden for genomewide association studies of nearly all common variants. Genet Epidemiol. 2008;32(4):381-385.
    • (2008) Genet Epidemiol , vol.32 , Issue.4 , pp. 381-385
    • Pe'Er, I.1    Yelensky, R.2    Altshuler, D.3    Daly, M.J.4
  • 28
    • 67649639047 scopus 로고    scopus 로고
    • Signaling at purinergic P2X receptors
    • Surprenant A, North RA. Signaling at purinergic P2X receptors. Annu Rev Physiol. 2009;71:333-359.
    • (2009) Annu Rev Physiol , vol.71 , pp. 333-359
    • Surprenant, A.1    North, R.A.2
  • 29
    • 0029665112 scopus 로고    scopus 로고
    • The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7)
    • Surprenant A, Rassendren F, Kawashima E, North RA, Buell G. The cytolytic P2Z receptor for extracellular ATP identified as a P2X receptor (P2X7). Science. 1996;272(5262):735-738.
    • (1996) Science , vol.272 , Issue.5262 , pp. 735-738
    • Surprenant, A.1    Rassendren, F.2    Kawashima, E.3    North, R.A.4    Buell, G.5
  • 30
    • 33750473352 scopus 로고    scopus 로고
    • Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor
    • Pelegrin P, Surprenant A. Pannexin-1 mediates large pore formation and interleukin-1β release by the ATP-gated P2X7 receptor. EMBO J. 2006;25(21):5071-5082.
    • (2006) EMBO J , vol.25 , Issue.21 , pp. 5071-5082
    • Pelegrin, P.1    Surprenant, A.2
  • 31
    • 0036118418 scopus 로고    scopus 로고
    • Purinergic signaling and vascular cell proliferation and death
    • Burnstock G. Purinergic signaling and vascular cell proliferation and death. Arterioscl Thromb Vasc Biol. 2002;22(3):364-373.
    • (2002) Arterioscl Thromb Vasc Biol , vol.22 , Issue.3 , pp. 364-373
    • Burnstock, G.1
  • 32
    • 32944470765 scopus 로고    scopus 로고
    • Cryopyrin activates the inflammasome in response to toxins and ATP
    • Mariathasan S, Weiss DS, Newton K, et al. Cryopyrin activates the inflammasome in response to toxins and ATP. Nature. 2006; 440(7081):228-232.
    • (2006) Nature , vol.440 , Issue.7081 , pp. 228-232
    • Mariathasan, S.1    Weiss, D.S.2    Newton, K.3
  • 33
    • 0036318476 scopus 로고    scopus 로고
    • Accurate assessment of β-cell function: The hyperbolic correction
    • 90001
    • Bergman RN, Ader M, Huecking K, Van Citters G. Accurate assessment of β-cell function: The hyperbolic correction. Diabetes. 2002;51(90001):S212-220.
    • (2002) Diabetes , vol.51 , pp. S212-S220
    • Bergman, R.N.1    Ader, M.2    Huecking, K.3    Van Citters, G.4
  • 34
    • 58149354288 scopus 로고    scopus 로고
    • Role of the ENPP1 K121Q polymorphism in glucose homeostasis
    • Baratta R, Rossetti P, Prudente S, et al. Role of the ENPP1 K121Q polymorphism in glucose homeostasis. Diabetes. 2008;57(12): 3360-3364.
    • (2008) Diabetes , vol.57 , Issue.12 , pp. 3360-3364
    • Baratta, R.1    Rossetti, P.2    Prudente, S.3
  • 35
    • 48249098981 scopus 로고    scopus 로고
    • Haplotype structure of the ENPP1 gene and nominal association of the K121Q polymorphism with glycemic traits in the Framingham Heart Study
    • Stolerman ES, Manning AK, McAteer JB, et al. Haplotype structure of the ENPP1 gene and nominal association of the K121Q polymorphism with glycemic traits in the Framingham Heart Study. Diabetes. 2008;57(7):1971-1977.
    • (2008) Diabetes , vol.57 , Issue.7 , pp. 1971-1977
    • Stolerman, E.S.1    Manning, A.K.2    McAteer, J.B.3
  • 36
    • 39149099952 scopus 로고    scopus 로고
    • The role of membrane glycoprotein PC-1/ENPP1 in the pathogenesis of insulin resistance and related abnormalities
    • Goldfine ID, Maddux BA, Youngren JF, et al. The role of membrane glycoprotein PC-1/ENPP1 in the pathogenesis of insulin resistance and related abnormalities. Endocr Rev. 2008;29(1):62-75.
    • (2008) Endocr Rev , vol.29 , Issue.1 , pp. 62-75
    • Goldfine, I.D.1    Maddux, B.A.2    Youngren, J.F.3
  • 37
    • 23044493861 scopus 로고    scopus 로고
    • Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes
    • Meyre D, Bouatia-Naji N, Tounian A, Samson C, Froguel P. Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. Nat Genet. 2005;37(8):863-867.
    • (2005) Nat Genet , vol.37 , Issue.8 , pp. 863-867
    • Meyre, D.1    Bouatia-Naji, N.2    Tounian, A.3    Samson, C.4    Froguel, P.5
  • 39
    • 60949083043 scopus 로고    scopus 로고
    • Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity
    • Chin CN, Dallas-Yang Q, Liu F, et al. Evidence that inhibition of insulin receptor signaling activity by PC-1/ENPP1 is dependent on its enzyme activity. Eur J Pharmacol. 2009;606(1-3):17-24.
    • (2009) Eur J Pharmacol , vol.606 , Issue.1-3 , pp. 17-24
    • Chin, C.N.1    Dallas-Yang, Q.2    Liu, F.3
  • 40
    • 64649104431 scopus 로고    scopus 로고
    • Functional ENTPD1 polymorphisms in African Americans with diabetes and end-stage renal disease
    • Friedman DJ, Talbert ME, Bowden DW, et al. Functional ENTPD1 polymorphisms in African Americans with diabetes and end-stage renal disease. Diabetes. 2009;58(4):999-1006.
    • (2009) Diabetes , vol.58 , Issue.4 , pp. 999-1006
    • Friedman, D.J.1    Talbert, M.E.2    Bowden, D.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.