Mitochondrial modulators in experimental Huntington's disease: Reversal of mitochondrial dysfunctions and cognitive deficits

Neurobiology of Aging

Volumn 36, Issue 6, 2015, Pages 2186-2200

  Mehrotra, Arpit ^a   Kanwal, Abhinav ^b   Banerjee, Sanjay Kumar ^b   Sandhir, Rajat ^a  

^a PANJAB UNIVERSITY   (India)

^b Translational Health Science and Technology Institute   (India)

Author keywords

3 Nitropropionic acid; Acetyl L carnitine; Alpha lipoic acid; Huntington's disease; Mitochondria; Oxidative stress

Indexed keywords

APOPTOSIS INDUCING FACTOR; BIM PROTEIN; CARBONYL DERIVATIVE; CASPASE 3; CASPASE 9; COMPLEX V; CYTOCHROME C; CYTOCHROME C OXIDASE; LEVACECARNINE; MALONALDEHYDE; MESSENGER RNA; NITRITE; OXIDOREDUCTASE; PROTEIN BAD; PROTEIN BAX; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); SUCCINATE DEHYDROGENASE (UBIQUINONE); THIOCTIC ACID; UBIQUINOL CYTOCHROME C REDUCTASE; UNCLASSIFIED DRUG; 3-NITROPROPIONIC ACID; ACETYLCARNITINE; NITRO DERIVATIVE; PROPIONIC ACID DERIVATIVE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; COGNITIVE DEFECT; CONTROLLED STUDY; DISORDERS OF MITOCHONDRIAL FUNCTIONS; DOWN REGULATION; DRUG EFFECT; ENZYME ACTIVITY; FEMALE; GENE EXPRESSION REGULATION; HISTOCHEMISTRY; HUNTINGTON CHOREA; MAZE TEST; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL RESPIRATION; MITOCHONDRION SWELLING; MORRIS WATER MAZE TEST; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; ULTRASTRUCTURE; Y MAZE TEST; ANIMAL; CHEMICALLY INDUCED; COGNITION DISORDERS; DRUG COMBINATION; DRUG EFFECTS; GENETICS; HUNTINGTON DISEASE; MITOCHONDRIAL DISEASES; MITOCHONDRION; PATHOLOGY; WISTAR RAT;

ACETYLCARNITINE; ANIMALS; COGNITION DISORDERS; DRUG THERAPY, COMBINATION; FEMALE; HUNTINGTON DISEASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; MITOCHONDRIA; MITOCHONDRIAL DISEASES; MITOCHONDRIAL SWELLING; NITRO COMPOUNDS; OXIDATIVE STRESS; PROPIONATES; RATS, WISTAR; THIOCTIC ACID;

EID: 84929207081     PISSN: 01974580     EISSN: 15581497     Source Type: Journal    
DOI: 10.1016/j.neurobiolaging.2015.02.004     Document Type: Article

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