Direct conversion of human fibroblasts into functional osteoblasts by defined factors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 112, Issue 19, 2015, Pages 6152-6157

  Yamamoto, Kenta ^a   Kishida, Tsunao ^a   Sato, Yoshiki ^a   Nishioka, Keisuke ^a   Ejima, Akika ^a   Fujiwara, Hiroyoshi ^a   Kubo, Toshikazu ^a   Yamamoto, Toshiro ^a   Kanamura, Narisato ^a   Mazda, Osam ^a  

^a KYOTO PREFECTURAL UNIVERSITY OF MEDICINE   (Japan)

Author keywords

Direct reprogramming; Osteoblasts; Regenerative medicine

Indexed keywords

ALKALINE PHOSPHATASE; MESSENGER RNA; MYC PROTEIN; OCTAMER TRANSCRIPTION FACTOR 4; OSTEOCALCIN; OSTEOPONTIN; TRANSCRIPTION FACTOR OSTERIX; TRANSCRIPTION FACTOR RUNX2; POU5F1 PROTEIN, HUMAN; RUNX2 PROTEIN, HUMAN; SP7 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ADIPOCYTE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BONE DEFECT; BONE MATRIX; BONE REGENERATION; BONE REMODELING; CARTILAGE CELL; CELL TRANSFORMATION; CONTROLLED STUDY; DNA METHYLATION; EPIGENETICS; FIBROBLAST; GENE EXPRESSION; GENE LOCUS; HUMAN; HUMAN CELL; MICRO-COMPUTED TOMOGRAPHY; MOUSE; NONHUMAN; OSSIFICATION; OSTEOBLAST; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; STABLE EXPRESSION; TRANSIENT EXPRESSION; ANIMAL; BONE; CALCINOSIS; CYTOLOGY; DNA MICROARRAY; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GINGIVA; MALE; METABOLISM; NONOBESE DIABETIC MOUSE; PATHOLOGY; SCID MOUSE;

MUS;

ANIMALS; BONE AND BONES; BONE REGENERATION; BONE REMODELING; CALCINOSIS; CORE BINDING FACTOR ALPHA 1 SUBUNIT; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GINGIVA; HUMANS; MALE; MICE; MICE, INBRED NOD; MICE, SCID; OCTAMER TRANSCRIPTION FACTOR-3; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OSTEOBLASTS; PHENOTYPE; PROTO-ONCOGENE PROTEINS C-MYC; RNA, MESSENGER; TRANSCRIPTION FACTORS;

EID: 84929179487     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1420713112     Document Type: Article

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