Rapid and repeatable fabrication of high A/R silk fibroin microneedles using thermally-drawn micromolds

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 94, Issue , 2015, Pages 11-19

  Lee, JiYong ^a   Park, Seung Hyun ^a   Seo, Il Ho ^a   Lee, Kang Ju ^a   Ryu, WonHyoung ^a  

^a Yonsei University   (South Korea)

Author keywords

Methanol treatment; Micromolding; Microneedles; Silk fibroin; Thermal drawing

Indexed keywords

METHANOL; POLYGLACTIN; RHODAMINE B; SILK FIBROIN; DELAYED RELEASE FORMULATION; DRUG CARRIER; FIBROIN; FIBROIN, SILKWORM; RHODAMINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; CRYSTALLIZATION; IN VITRO STUDY; MICROMOLDING; MICRONEEDLE; MICROTECHNOLOGY; NONHUMAN; PHARMACEUTICAL ENGINEERING; PORCINE MODEL; SCANNING ELECTRON MICROSCOPY; SUSTAINED DRUG RELEASE; THERMAL DRAWING; ANIMAL; CHEMISTRY; DELAYED RELEASE FORMULATION; DEVICES; EQUIPMENT DESIGN; EVALUATION STUDY; INTRADERMAL DRUG ADMINISTRATION; KINETICS; MATERIALS TESTING; MEDICINAL CHEMISTRY; METABOLISM; MINIATURIZATION; NEEDLE; PHARMACEUTICS; PIG; PROCEDURES; SKIN; SOLUBILITY; SURFACE PROPERTY; TEMPERATURE;

ANIMALS; CHEMISTRY, PHARMACEUTICAL; DELAYED-ACTION PREPARATIONS; DRUG CARRIERS; EQUIPMENT DESIGN; FIBROINS; IN VITRO TECHNIQUES; INJECTIONS, INTRADERMAL; KINETICS; MATERIALS TESTING; METHANOL; MINIATURIZATION; NEEDLES; RHODAMINES; SKIN; SOLUBILITY; SURFACE PROPERTIES; SWINE; TECHNOLOGY, PHARMACEUTICAL; TEMPERATURE;

EID: 84929162907     PISSN: 09396411     EISSN: 18733441     Source Type: Journal    
DOI: 10.1016/j.ejpb.2015.04.024     Document Type: Article

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