Fabrication of silk microneedles for controlled-release drug delivery

Advanced Functional Materials

Volumn 22, Issue 2, 2012, Pages 330-335

  Tsioris, Konstantinos ^a   Raja, Waseem K ^a   Pritchard, Eleanor M ^a   Panilaitis, Bruce ^a   Kaplan, David L ^a   Omenetto, Fiorenzo G ^a  

^a Tufts University   (United States)

Author keywords

biopolymers; drug delivery; microneedles; protein stability; silk microfabrication

Indexed keywords

BACTERIAL DENSITY; BIO-CHEMICAL COMPOUNDS; BIOLOGICAL COMPOUNDS; BULK LOADING; CONTROLLED RELEASE; DEGRADATION RATE; DIFFUSION RATE; DRUG DELIVERY SYSTEM; DRUG-RELEASE RATE; FABRICATION METHOD; FURTHER DEVELOPMENT; HIGH ASPECT RATIO; HYPODERMIC NEEDLES; IN-VITRO; MATERIAL SYSTEMS; MATRIX; MICROMOLDING; MICRONEEDLES; MINIMALLY INVASIVE; MODEL DRUGS; POSSIBLE SOLUTIONS; POST-PROCESSING CONDITION; PROCESSING CONDITION; PROTEIN STABILITY; RELEASE KINETICS; ROOM TEMPERATURE; SILK FIBROIN; SILK PROTEINS;

ASPECT RATIO; BIOCOMPATIBILITY; BIODEGRADATION; BIOLOGICAL MATERIALS; BIOMOLECULES; BIOPOLYMERS; DEGRADATION; DRUG DELIVERY; FABRICATION; MECHANICAL PROPERTIES; MICROMACHINING; MICROSTRUCTURE; MOLDING; NEEDLES; PROTEINS; SILK;

CONTROLLED DRUG DELIVERY;

EID: 84856090257     PISSN: 1616301X     EISSN: 16163028     Source Type: Journal    
DOI: 10.1002/adfm.201102012     Document Type: Article

References (40)

1. A. Arora, M. Prausnitz, S. Mitragotri, Int. J. Pharm. 2008, 364, 227.
2. J. H. Park, M. G. Allen, M. R. Prausnitz, Pharm. Res. 2006, 23, 1008.
3. S. Sullivan, D. Koutsonanos, M. del Pilar Martin, J. Lee, V. Zarnitsyn, S. Choi, N. Murthy, R. Compans, I. Skountzou, M. Prausnitz, Natu. Med. 2010, 16, 915.
4. Y. C. Kim, F. S. Quan, R. W. Compans, S. M. Kang, M. R. Prausnitz, J. Controlled Release 2010, 142, 187.
5. Y. C. Kim, F. S. Quan, R. W. Compans, S. M. Kang, M. R. Prausnitz, Pharm. Res. 2011, 28, 135.
6. R. F. Donnelly, D. I. J. Morrow, T. R. R. Singh, K. Migalska, P. A. McCarron, C. O'Mahony, A. D. Woolfson, Drug Dev. Ind. Pharm. 2009, 35, 1242.
7. S. Sullivan, N. Murthy, M. Prausnitz, Adv. Mater. 2008, 20, 933.
8. X. You, J. J. Pak, J.-h. Chang, Proc. IEEE, Int. Conf. on Nano/Molecular Med. and Eng. 2010, 144.
9. S. Davis, B. Landis, Z. Adams, M. Allen, M. Prausnitz, J. Biomech. 2004, 37, 1155.
10. G. Altman, F. Diaz, C. Jakuba, T. Calabro, R. Horan, J. Chen, H. Lu, J. Richmond, D. Kaplan, Biomaterials 2003, 24, 401.
11. C. Jiang, X. Wang, R. Gunawidjaja, Y. Lin, M. Gupta, D. Kaplan, R. Naik, V. Tsukruk, Adv. Funct. Mater. 2007, 17, 2229.
12. S. Lu, X. Wang, Q. Lu, X. Hu, N. Uppal, F. Omenetto, D. Kaplan, Biomacromolecules 2009, 217.
13. S. Lu, X. Wang, Q. Lu, X. Hu, N. Uppal, F. Omenetto, D. Kaplan, Biomacromolecules 2009, 10, 1032.
14. J. Amsden, H. Perry, S. Boriskina, A. Gopinath, D. Kaplan, L. Dal Negro, F. Omenetto, Opt. Express 2009, 17, 21271.
15. F. Omenetto, D. Kaplan, Nat. Photonics 2008, 2, 641.
16. H. Perry, A. Gopinath, D. Kaplan, L. Dal Negro, F. Omenetto, Adv. Mater. 2008, 20, 3070.
17. K. Tsioris, H. Tao, M. Liu, J. Hopwood, D. Kaplan, R. Averitt, F. Omenetto, Adv. Mater. 2011, 23, 2015.
18. J. Chen, N. Minoura, A. Tanioka, Polymer 1994, 35, 2853.
19. X. Y. Liu, C. C. Zhang, W. L. Xu, C. Ouyang, Mater. Lett. 2009, 63, 263.
20. S. Putthanarat, R. Eby, R. Naik, S. Juhl, M. Walker, E. Peterman, S. Ristich, J. Magoshi, T. Tanaka, M. Stone, Polymer 2004, 45, 8451.
21. L. Uebersax, H. Hagenmuller, S. Hofmann, E. Gruenblatt, R. Muller, G. Vunjaknovakovic, D. L. Kaplan, H. P. Merkle, L. Meinel, Tissue Eng. 2006, 12, 3417.
22. H. Jin, J. Park, V. Karageorgiou, U. Kim, R. Valluzzi, P. Cebe, D. Kaplan, Adv. Funct. Mater. 2005, 15, 1241.
23. A. Sionkowska, M. Wisniewski, J. Skopinska, S. Vicini, E. Marsano, Polym. Degrad. Stab. 2005, 88, 261.
24. C. Cullander, R. H. Guy, Adv. Drug Delivery Rev. 1992, 8, 291.
25. H. Kwak, W. Shim, M. Choi, M. Son, Y. Kim, H. Yang, T. Kim, G. Lee, B. Kim, S. Kang, J. Controlled Release 2009, 137, 160.
26. J. W. Lee, S. O. Choi, E. I. Felner, M. R. Prausnitz, Small 2011, 7, 531.
27. J. Kemp, M. Kajihara, S. Nagahara, A. Sano, M. Brandon, S. Lofthouse, Vaccine 2002, 20, 1089.
28. D. B. Wolfe, D. Qin, G. M. Whitesides, Methods Mol. Biol. 2010, 583, 81.
29. S. Bhattacharya, A. Datta, J. M. Berg, S. Gangopadhyay, J. Microelectromech. Syst. 2005, 14, 590.
30. L. Fritz, D. Hofmann, Polymer 1997, 38, 1035.
31. Q. Lu, X. Hu, X. Wang, J. A. Kluge, S. Lu, P. Cebe, D. L. Kaplan, Acta Biomater. 2010, 6, 1380.
32. S. Hofmann, C. Wong Po Foo, F. Rossetti, M. Textor, G. Vunjak-Novakovic, D. Kaplan, H. Merkle, L. Meinel, J. Controlled Release 2006, 111, 219.
33. X. Hu, D. Kaplan, P. Cebe, Macromolecules 2006, 39, 6161.
34. E. M. Pritchard, C. Szybala, D. Boison, D. L. Kaplan, J. Controlled Release 2010, 144, 159.
35. X. Wang, X. Hu, A. Daley, O. Rabotyagova, P. Cebe, D. L. Kaplan, J. Controlled Release 2007, 121, 190.
36. G. Wightman, J. Beard, R. Allison, Forensic Sci. Int. 2010, 200, 41.
37. B. Forslind, M. Lindberg, G. M. Roomans, J. Pallon, Y. Werner-Linde, Microsc. Res. Tech. 1997, 38, 373.
38. W. Montagna, P. F. Parakkal, The Structure and Function of Skin, Academic Press, New York 1974.
39. S. Sofia, M. B. McCarthy, G. Gronowicz, D. L. Kaplan, J. Biomed. Mater. Res. 2001, 54, 139.
40. J. H. Park, M. G. Allen, M. R. Prausnitz, J. Controlled Release 2005, 104, 51.