Rapid and persistent delivery of antigen by lymph node targeting PRINT nanoparticle vaccine carrier to promote humoral immunity

Molecular Pharmaceutics

Volumn 12, Issue 5, 2015, Pages 1356-1365

  Mueller, Sarah N ^a   Tian, Shaomin ^b,c   Desimone, Joseph M ^a,c,d,e  

^a The University of North Carolina at Chapel Hill   (United States)

^b UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

^d North Carolina State University   (United States)

^e MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

Author keywords

lymphatic trafficking; particulate vaccine; PEGylation; PRINT

Indexed keywords

ALUMINUM POTASSIUM SULFATE; DRUG CARRIER; MACROGOL; NANOPARTICLE; OVALBUMIN; SUBUNIT VACCINE; ANTIGEN; MACROGOL DERIVATIVE;

ANIMAL EXPERIMENT; ANTIGEN PRESENTATION; ANTIGEN PRESENTING CELL; ANTIGEN SPECIFICITY; ARTICLE; B LYMPHOCYTE; BIOCOMPATIBILITY; CD4+ T LYMPHOCYTE; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM; DRUG DELIVERY SYSTEM; EXTRACELLULAR MATRIX; FEMALE; HELPER CELL; HUMORAL IMMUNITY; HYDROGEL; IMMUNE RESPONSE; IMMUNE SYSTEM; IMMUNOGENICITY; IN VIVO STUDY; INFECTION; LYMPH NODE; LYMPHATIC SYSTEM; LYMPHOCYTE PROLIFERATION; MOUSE; NONHUMAN; PARTICLE REPLICATION IN NONWETTING TEMPLATE; PRIORITY JOURNAL; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; CONFOCAL MICROSCOPY; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; METABOLISM; PHYSIOLOGY; SCANNING ELECTRON MICROSCOPY;

ANIMALS; ANTIGENS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; IMMUNITY, HUMORAL; LYMPH NODES; MICE; MICE, INBRED BALB C; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING; NANOPARTICLES; POLYETHYLENE GLYCOLS;

EID: 84929152856     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp500589c     Document Type: Article

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