Sirtuin inhibition induces apoptosis-like changes in platelets and thrombocytopenia

Journal of Biological Chemistry

Volumn 290, Issue 19, 2015, Pages 12290-12299

  Kumari, Sharda ^a   Chaurasia, Susheel N ^a   Nayak, Manasa K ^a   Mallick, Ram L ^a   Dash, Debabrata ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOELECTRIC POTENTIALS; CELL DEATH; DRUG PRODUCTS; INDIUM PLATING;

ANTI-TUMOR ACTIVITIES; CELL-PERMEABLE; HISTONE DEACETYLASES; INDUCED APOPTOSIS; LACTONE RINGS; MITOCHONDRIAL TRANSMEMBRANE POTENTIALS; REACTIVE OXYGEN SPECIES; THROMBOCYTOPENIA;

PLATELETS;

CALPAIN; LIPOCORTIN 5; PROTEIN BAX; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SELISISTAT; SIRTINOL; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; BAX PROTEIN, MOUSE; SIRT1 PROTEIN, HUMAN; SIRT1 PROTEIN, MOUSE; SIRT2 PROTEIN, HUMAN; SIRT3 PROTEIN, HUMAN; SIRT3 PROTEIN, MOUSE;

APOPTOSIS; ARTICLE; CELL ISOLATION; CONFORMATION; CONTROLLED STUDY; FLOW CYTOMETRY; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; MACROPHAGE; MITOCHONDRIAL MEMBRANE POTENTIAL; MONOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION; RNA EXTRACTION; THROMBOCYTE; THROMBOCYTE COUNT; THROMBOCYTOPENIA; WESTERN BLOTTING; ANIMAL; BLOOD; CELL NUCLEUS; CHEMISTRY; CYTOLOGY; GENE EXPRESSION REGULATION; MEMBRANE POTENTIAL; METABOLISM; MOUSE; PHAGOCYTOSIS; THROMBOSIS;

MUS;

ANIMALS; ANNEXIN A5; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOOD PLATELETS; CELL NUCLEUS; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HUMANS; MACROPHAGES; MEMBRANE POTENTIALS; MICE; PHAGOCYTOSIS; PLATELET COUNT; REACTIVE OXYGEN SPECIES; SIRTUIN 1; SIRTUIN 2; SIRTUIN 3; THROMBOCYTOPENIA; THROMBOSIS;

EID: 84929120921     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M114.615948     Document Type: Article

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