UV light potentiates STING (stimulator of interferon genes)-dependent innate immune signaling through deregulation of ULK1 (Unc51-like kinase 1)

Journal of Biological Chemistry

Volumn 290, Issue 19, 2015, Pages 12184-12194

  Kemp, Michael G ^a   Lindsey Boltz, Laura A ^a   Sancar, Aziz ^a  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; ANTIBIOTICS; CHEMICAL ACTIVATION; DEREGULATION; DNA; ENZYMES; GLYCOPROTEINS; IMMUNE SYSTEM; SIGNALING; TRANSCRIPTION;

APOPTOTIC SIGNALING; AUTOIMMUNE DISORDER; INNATE IMMUNE RESPONSE; INNATE IMMUNE SYSTEMS; INTERFERON REGULATORY FACTOR 3; LUPUS ERYTHEMATOSUS; ULTRAVIOLET WAVELENGTH; UV-INDUCED DNA DAMAGE;

CELL SIGNALING;

CARCINOGEN; DNA; INTERFERON REGULATORY FACTOR 3; MEMBRANE PROTEIN; PROTEIN KINASE; STIMULATOR OF INTERFERON GENE; UNC51 LIKE KINASE 1; UNCLASSIFIED DRUG; INTERFERON; IRF3 PROTEIN, HUMAN; MPYS PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; SIGNAL PEPTIDE; ULK1 PROTEIN, HUMAN;

APOPTOSIS; ARTICLE; AUTOPHAGY; CELLULAR STRESS RESPONSE; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENZYME DEFECT; ENZYME REGULATION; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREGULATION; INNATE IMMUNITY; INTRACELLULAR SIGNALING; KERATINOCYTE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; SUN EXPOSURE; SUNLIGHT; ULTRAVIOLET RADIATION; AUTOIMMUNITY; CELL LINE; GENE EXPRESSION REGULATION; HEK293 CELL LINE; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

APOPTOSIS; AUTOIMMUNITY; AUTOPHAGY; CELL LINE; DNA DAMAGE; DNA REPAIR; GENE EXPRESSION REGULATION; HEK293 CELLS; HUMANS; IMMUNITY, INNATE; INTERFERON REGULATORY FACTOR-3; INTERFERONS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; KERATINOCYTES; MEMBRANE PROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; SIGNAL TRANSDUCTION; ULTRAVIOLET RAYS;

EID: 84929118910     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M115.649301     Document Type: Article

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