Decreasing initial telomere length in humans intergenerationally understates age-associated telomere shortening

Aging Cell

Volumn 14, Issue 4, 2015, Pages 669-677

  Holohan, Brody ^a   De Meyer, Tim ^b   Batten, Kimberly ^a   Mangino, Massimo ^c,d   Hunt, Steven C ^e   Bekaert, Sofie ^f   De Buyzere, Marc L ^f   Rietzschel, Ernst R ^f   Spector, Tim D ^c   Wright, Woodring E ^a   Shay, Jerry W ^a,g  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b GHENT UNIVERSITY   (Belgium)

^c KING'S COLLEGE LONDON   (United Kingdom)

^d ST THOMAS HOSPITAL   (United Kingdom)

^e UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^f GHENT UNIVERSITY HOSPITAL   (Belgium)

^g KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

Author keywords

Aging; Genetics; Human; Parental effects; Secular trend; Telomerase; Telomere length; Telomeres

Indexed keywords

TELOMERASE; TERT PROTEIN, HUMAN;

AGING; CHEMISTRY; CROSS-SECTIONAL STUDY; FEMALE; GENE EXPRESSION; GENETICS; HUMAN; INFORMATION PROCESSING; INHERITANCE; LONGITUDINAL STUDY; MALE; PATERNAL AGE; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING;

AGING; CROSS-SECTIONAL STUDIES; DATASETS AS TOPIC; FEMALE; GENE EXPRESSION; HUMANS; INHERITANCE PATTERNS; LONGITUDINAL STUDIES; MALE; PATERNAL AGE; TELOMERASE; TELOMERE; TELOMERE HOMEOSTASIS; TELOMERE SHORTENING;

EID: 84929094429     PISSN: 14749718     EISSN: 14749726     Source Type: Journal    
DOI: 10.1111/acel.12347     Document Type: Article

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