Cutting edge: Differential regulation of PTEN by TCR, Akt, and FoxO1 controls CD4+ T cell fate decisions

Journal of Immunology

Volumn 194, Issue 10, 2015, Pages 4615-4619

  Hawse, William F ^a   Sheehan, Robert P ^a   Miskov Zivanov, Natasa ^a,b   Menk, Ashley V ^a   Kane, Lawrence P ^a   Faeder, James R ^a   Morel, Penelope A ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b Carnegie Mellon University ^*  (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; MAMMALIAN TARGET OF RAPAMYCIN; MESSENGER RNA; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; T LYMPHOCYTE RECEPTOR; TRANSCRIPTION FACTOR FKHR; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; PTEN PROTEIN, MOUSE; SMALL INTERFERING RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CARBOXY TERMINAL SEQUENCE; CD4+ T LYMPHOCYTE; CELL FATE; CONTROLLED STUDY; FEEDBACK SYSTEM; IMMUNOREGULATION; LYMPHOCYTE DIFFERENTIATION; MATHEMATICAL MODEL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; TRANSCRIPTION REGULATION; ANIMAL; C57BL MOUSE; CELL DIFFERENTIATION; CELL LINEAGE; CHROMATIN IMMUNOPRECIPITATION; CYTOLOGY; FLOW CYTOMETRY; GENE SILENCING; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; THEORETICAL MODEL; WESTERN BLOTTING;

ANIMALS; BLOTTING, WESTERN; CD4-POSITIVE T-LYMPHOCYTES; CELL DIFFERENTIATION; CELL LINEAGE; CHROMATIN IMMUNOPRECIPITATION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; GENE KNOCKDOWN TECHNIQUES; LYMPHOCYTE ACTIVATION; MICE; MICE, INBRED C57BL; MODELS, THEORETICAL; ONCOGENE PROTEIN V-AKT; PTEN PHOSPHOHYDROLASE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, ANTIGEN, T-CELL; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION;

EID: 84929087065     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1402554     Document Type: Article

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