MicroRNA-124 suppresses oral squamous cell carcinoma motility by targeting ITGB1

FEBS Letters

Volumn 585, Issue 1, 2011, Pages 187-192

  Hunt, Stuart ^a   Jones, Adam V ^a   Hinsley, Emma E ^a   Whawell, Simon A ^a   Lambert, Daniel W ^a  

^a UNIVERSITY OF SHEFFIELD   (United Kingdom)

Author keywords

Integrin beta 1; Invasion; miR 124; Oral cancer

Indexed keywords

BETA1 INTEGRIN; MICRORNA; MICRORNA 124; UNCLASSIFIED DRUG; UNTRANSLATED RNA;

3' UNTRANSLATED REGION; ARTICLE; CANCER CELL; CANCER GROWTH; CARCINOGENESIS; CELL ADHESION; CELL MOTILITY; CONTROLLED STUDY; DOWN REGULATION; GENE OVEREXPRESSION; GENE REPRESSION; HUMAN; HUMAN CELL; MOLECULAR MECHANICS; MOUTH CARCINOMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN TARGETING; SQUAMOUS CELL CARCINOMA;

3' UNTRANSLATED REGIONS; ANTIGENS, CD29; BINDING SITES; BLOTTING, WESTERN; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL LINE, TUMOR; CELL MOVEMENT; DOWN-REGULATION; HUMANS; LUCIFERASES; MICRORNAS; MOUTH NEOPLASMS; MUTAGENESIS, SITE-DIRECTED; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA INTERFERENCE;

EID: 78650864750     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2010.11.038     Document Type: Article

References (21)

1. P.R. Brocklehurst, S.R. Baker, and P.M. Speight Oral cancer screening: what have we learnt and what is there still to achieve? Future Oncol. 6 2010 299 304
2. B.L. Ziober, S.S. Silverman Jr., and R.H. Kramer Adhesive mechanisms regulating invasion and metastasis in oral cancer Crit. Rev. Oral Biol. Med. 12 2001 499 510
3. S.M. Janes, and F.M. Watt New roles for integrins in squamous-cell carcinoma Nat. Rev. Cancer 6 2006 175 183
4. J. Jones, M. Sugiyama, F.M. Watt, and P.M. Speight Integrin expression in normal, hyperplastic, dysplastic, and malignant oral epithelium J. Pathol. 169 1993 235 243
5. G. Gabriely, T. Wurdinger, S. Kesari, C.C. Esau, J. Burchard, P.S. Linsley, and A.M. Krichevsky MicroRNA 21 promotes glioma invasion by targeting matrix metalloproteinase regulators Mol. Cell Biol. 28 2008 5369 5380
6. Y. Zeng, R. Yi, and B.R. Cullen Recognition and cleavage of primary microRNA precursors by the nuclear processing enzyme Drosha EMBO J. 24 2005 138 148
7. N. Bushati, and S.M. Cohen MicroRNA functions Annu. Rev. Cell Dev. Biol. 23 2007 175 205
8. G.A. Calin, and C.M. Croce MicroRNA signatures in human cancers Nat. Rev. Cancer 6 2006 857 866
9. A.B. Hui, M. Lenarduzzi, T. Krushel, L. Waldron, M. Pintilie, W. Shi, B. Perez-Ordonez, I. Jurisica, B. O'Sullivan, J. Waldron, P. Gullane, B. Cummings, and F.F. Liu Comprehensive microRNA profiling for head and neck squamous cell carcinomas Clin. Cancer Res. 15 2010 1129 1139
10. G. Li, C. Luna, J. Qiu, D.L. Epstein, and P. Gonzalez Targeting of integrin beta 1 and kinesin 2 alpha by miR-183 J. Biol. Chem. 285 2009 5461 5471
11. K. Lindberg, A. Strom, J.G. Lock, J.A. Gustafsson, L.A. Haldosen, and L.A. Helguero Expression of estrogen receptor beta increases integrin alpha1 and integrin beta1 levels and enhances adhesion of breast cancer cells J. Cell Physiol. 222 2010 156 167
12. T. Yu, X.Y. Wang, R.G. Gong, A. Li, S. Yang, Y.T. Cao, Y.M. Wen, C.M. Wang, and X.Z. Yi The expression profile of microRNAs in a model of 7, 12-dimethyl-benz[a]anthrance-induced oral carcinogenesis in Syrian hamster J. Exp. Clin. Cancer Res. 28 2009 64
13. R.D. Evans, V.C. Perkins, A. Henry, P.E. Stephens, M.K. Robinson, and F.M. Watt A tumor-associated beta 1 integrin mutation that abrogates epithelial differentiation control J. Cell Biol. 160 2003 589 596
14. J. Jones, F.M. Watt, and P.M. Speight Changes in the expression of alpha v integrins in oral squamous cell carcinomas J. Oral Pathol. Med. 26 1997 63 68
15. G.J. Thomas, M.P. Lewis, S.A. Whawell, A. Russell, D. Sheppard, I.R. Hart, P.M. Speight, and J.F. Marshall Expression of the alphavbeta6 integrin promotes migration and invasion in squamous carcinoma cells J. Invest. Dermatol. 117 2001 67 73
16. M. Furuta, K.I. Kozaki, S. Tanaka, S. Arii, I. Imoto, and J. Inazawa MiR-124 and miR-203 are epigenetically silenced tumor-suppressive microRNAs in hepatocellular carcinoma Carcinogenesis 31 2010 766 776
17. X. Agirre, A. Vilas-Zornoza, A. Jimenez-Velasco, J.I. Martin-Subero, L. Cordeu, L. Garate, E. San Jose-Eneriz, G. Abizanda, P. Rodriguez-Otero, P. Fortes, J. Rifon, E. Bandres, M.J. Calasanz, V. Martin, A. Heiniger, A. Torres, R. Siebert, J. Roman-Gomez, and F. Prosper Epigenetic silencing of the tumor suppressor microRNA Hsa-miR-124a regulates CDK6 expression and confers a poor prognosis in acute lymphoblastic leukemia Cancer Res. 69 2009 4443 4453
18. X. Cao, S.L. Pfaff, and F.H. Gage A functional study of miR-124 in the developing neural tube Genes Dev. 21 2007 531 536
19. P. Saetrom, B.S. Heale, O. Snove Jr., L. Aagaard, J. Alluin, and J.J. Rossi Distance constraints between microRNA target sites dictate efficacy and cooperativity Nucleic Acids Res. 35 2007 2333 2342
20. J. Liu Control of protein synthesis and mRNA degradation by microRNAs Curr. Opin. Cell Biol. 20 2008 214 221
21. Valastyan, S. and Weinberg, R.A. (2010) miR-31: a crucial overseer of tumor metastasis and other emerging roles. Cell Cycle 9, Epub ahead of print.