IL-17-producing CD4+ T cells contribute to the loss of B-cell tolerance in experimental autoimmune myasthenia gravis

European Journal of Immunology

Volumn 45, Issue 5, 2015, Pages 1339-1347

  Schaffert, Hanne ^a   Pelz, Andreas ^a   Saxena, Abhishek ^b   Losen, Mario ^b   Meisel, Andreas ^a   Thiel, Andreas ^a   Kohler, Siegfried ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b MAASTRICHT UNIVERSITY   (Netherlands)

Author keywords

Autoantibodies; B cell tolerance; Experimental autoimmune myasthenia gravis; IgG subtypes; IL 17; Th17 cells

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G2B; INTERLEUKIN 17; INTERLEUKIN 2; INTERLEUKIN 21; TRANSCRIPTION FACTOR FOXP3; ANTIGEN; CHOLINERGIC RECEPTOR; IMMUNOGLOBULIN G; LYMPHOCYTE ANTIGEN RECEPTOR;

ANIMAL CELL; ANIMAL MODEL; ANTIBODY PRODUCTION; ARTICLE; AUTOIMMUNITY; B LYMPHOCYTE; CD4+ T LYMPHOCYTE; CELL LOSS; CELLULAR SECRETION; CONTROLLED STUDY; EXPERIMENTAL AUTOIMMUNE MYASTHENIA GRAVIS; IMMUNOPATHOGENESIS; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; TH17 CELL; WILD TYPE MOUSE; ADOPTIVE TRANSFER; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DEFICIENCY; GENETICS; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL; TORPEDO;

ADOPTIVE TRANSFER; ANIMALS; ANTIGENS; B-LYMPHOCYTES; IMMUNE TOLERANCE; IMMUNOGLOBULIN G; INTERLEUKIN-17; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MYASTHENIA GRAVIS, AUTOIMMUNE, EXPERIMENTAL; RECEPTORS, ANTIGEN, T-CELL, ALPHA-BETA; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; RECEPTORS, CHOLINERGIC; TH17 CELLS; TORPEDO;

EID: 84929029422     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.201445064     Document Type: Article

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