Diagnostic urinary proteome profile for immunoglobulin a nephropathy

Iranian Journal of Kidney Diseases

Volumn 9, Issue 3, 2015, Pages 239-248

  Samavat, Shiva ^a,b   Kalantari, Shiva ^c   Nafar, Mohsen ^c   Rutishauser, Dorothea ^d,e   Rezaei Tavirani, Mostafa ^c,f   Parvin, Mahmud ^a   Zubarev, Roman A ^d,e  

^a SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d KAROLINSKA INSTITUTE   (Sweden)

^e SCIENCE FOR LIFE LABORATORY   (Sweden)

^f SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

IgA glomerulonephritis; Mass spectrometry; Proteomics; Urine

Indexed keywords

ALPHA 2 ANTIPLASMIN; CD150 ANTIGEN; COMPLEMENT COMPONENT C7; DECAY ACCELERATING FACTOR; DIPEPTIDYL PEPTIDASE IV; EPIDERMAL GROWTH FACTOR; HERMES ANTIGEN; PROTEOME; UTEROGLOBIN; BIOLOGICAL MARKER;

ADULT; ARTICLE; CLINICAL ARTICLE; COMPLEMENT SYSTEM; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE ONTOLOGY; GLOMERULUS FILTRATION RATE; HUMAN; IMMUNOGLOBULIN A NEPHROPATHY; INFLAMMATION; LIQUID CHROMATOGRAPHY; MALE; MIDDLE AGED; PRINCIPAL COMPONENT ANALYSIS; PROTEINURIA; TANDEM MASS SPECTROMETRY; UPREGULATION; YOUNG ADULT; BIOPSY; GLOMERULONEPHRITIS, IGA; KIDNEY; MULTIVARIATE ANALYSIS; PATHOLOGY; PEPTIDE MAPPING; PROCEDURES; PROTEIN MICROARRAY; PROTEOMICS; URINE;

ADULT; BIOMARKERS; BIOPSY; CHROMATOGRAPHY, LIQUID; FEMALE; GLOMERULONEPHRITIS, IGA; HUMANS; KIDNEY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PEPTIDE MAPPING; PROTEIN ARRAY ANALYSIS; PROTEOME; PROTEOMICS; TANDEM MASS SPECTROMETRY;

EID: 84928991096     PISSN: 17358582     EISSN: 17358604     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Floege J, Feehally J. Treatment of IgA nephropathy and Henoch-Schonlein nephritis. Nat Rev Nephrol. 2013;9:320-7.
2. Schena FP. Immunoglobulin a nephropathy with mild renal lesions: a call in the forest for physicians and nephrologists. Am J Med. 2001;110:499-500.
3. Tumlin JA, Madaio MP, Hennigar R. Idiopathic IgA nephropathy: pathogenesis, histopathology, and therapeutic options. Clin J Am Soc Nephrol. 2007;2:1054-61.
4. Nasri H, Baradaran A. Aggravation of immunoglobulin a nephropathy by hyperuricemia: a mini-review on current findings and new concepts. Iran J Kidney Dis. 2014;8:359-62.
5. Berger J, Hinglais N. [Intercapillary deposits of IgA-IgG]. J Urol Nephrol (Paris). 1968;74:694-5.
6. Duque N, Gomez-Guerrero C, Egido J. Interaction of IgA with Fc alpha receptors of human mesangial cells activates transcription factor nuclear factor-kappa B and induces expression and synthesis of monocyte chemoattractant protein-1, IL-8, and IFN-inducible protein 10. J Immunol. 1997;159:3474-82.
7. Chan LY, Leung JC, Tsang AW, Tang SC, Lai KN. Activation of tubular epithelial cells by mesangial-derived TNF-alpha: glomerulotubular communication in IgA nephropathy. Kidney Int. 2005;67:602-12.
8. Niemir ZI, Stein H, Noronha IL, et al. PDGF and TGFbeta contribute to the natural course of human IgA glomerulonephritis. Kidney Int. 1995;48:1530-41.
9. Wada T, Nangaku M. Novel roles of complement in renal diseases and their therapeutic consequences. Kidney Int. 2013;84:441-50.
10. Coppo R, Camilla R, Amore A, et al. Toll-like receptor 4 expression is increased in circulating mononuclear cells of patients with immunoglobulin A nephropathy. Clin Exp Immunol. 2010;159:73-81.
11. Suzuki H, Suzuki Y, Narita I, et al. Toll-like receptor 9 affects severity of IgA nephropathy. J Am Soc Nephrol. 2008;19:2384-95.
12. Zhang X, Wu X, Xiong L, et al. Role of vitamin D3 in regulation of T helper cell 17 and regulatory T-cell balance in rats with immunoglobulin a nephropathy. Iran J Kidney Dis. 2014;8:363-70.
13. Lai K N. Pathogenesis of IgA nephropathy. Nat Rev Nephrol. 2012;8:275-83.
14. Haubitz M, Wittke S, Weissinger EM, et al. Urine protein patterns can serve as diagnostic tools in patients with IgA nephropathy. Kidney Int. 2005;67:2313-20.
15. Kalantari S, Rutishauser D, Samavat S, et al. Urinary prognostic biomarkers and classification of IgA nephropathy by high resolution mass spectrometry coupled with liquid chromatography. PLoS One. 2013;8:e80830.
16. Rappsilber J, Ishihama Y, Mann M. Stop and go extraction tips for matrix-assisted laser desorption/ionization, nanoelectrospray, and LC/MS sample pretreatment in proteomics. Anal Chem. 2003;75:663-70.
17. Linden M, Lind SB, Mayrhofer C, et al. Proteomic analysis of urinary biomarker candidates for nonmuscle invasive bladder cancer. Proteomics. 2012;12:135-44.
18. Geladi P, Esbensen K. Regression on multivariate images principal component regression for modeling, prediction and visual diagnostic-tools. J Chemometr. 1991;5:97-111.
19. Wold S, Jonsson J, Sjostrom M, et al. DNA and peptide sequences and chemical processes multivariately modeled by principal component analysis and partial least-Squares projections to latent structures. Anal Chim Acta. 1993;277:239-53.
20. Geladi P, Kowalski B. Partial least squares regression: a tutorial. Anal Chim Acta. 1986;185:1-17.
21. Dennis G, Jr., Sherman BT, Hosack DA, et al. DAVID: Database for Annotation, Visualization, and Integrated Discovery. Genome Biol. 2003;4:3.
22. Broadhurst DI, Kell DB. Statistical strategies for avoiding false discoveries in metabolomics and related experiments. Metabolomics. 2006;2:171-96.
23. Sano N, Kitazawa K, Sugisaki T. Localization and roles of CD44, hyaluronic acid and osteopontin in IgA nephropathy. Nephron. 2001;89:416-21.
24. Florquin S, Nunziata R, Claessen N, van den Berg FM, Pals ST, Weening JJ. CD44 expression in IgA nephropathy. Am J Kidney Dis. 2002;39:407-14.
25. Rouschop KM, Sewnath ME, Claessen N, et al. CD44 deficiency increases tubular damage but reduces renal fibrosis in obstructive nephropathy. J Am Soc Nephrol. 2004;15:674-86.
26. Qiaoling Z, Xiaoyun J, Wei W, Shuhong D, Yaqin P, Xiaoqing G. Altered P-selectin and CD44 expression in the renal tissues and peripheral blood of children with IgA nephropathy. Int Urol Nephrol. 2009;41:703-11.
27. Ganfornina MD, Do CS, Lora JM, et al. Apolipoprotein D is involved in the mechanisms regulating protection from oxidative stress. Aging Cell. 2008;7:506-15.
28. Blanco-Vaca F, Pownall HJ. Disulfide linked dimers of apolipoprotein D in urine. Electrophoresis. 1993;14:1086-7.
29. Aregger F, Uehlinger DE, Witowski J, et al. Identification of IGFBP-7 by urinary proteomics as a novel prognostic marker in early acute kidney injury. Kidney Int. 2014;85:909-19.
30. Vivekanandan-Giri A, Slocum JL, Buller CL, et al. Urine glycoprotein profile reveals novel markers for chronic kidney disease. Int J Proteomics. 2011;2011:214715.
31. Su T, Chapin SJ, Bryant DM, Shewan AM, Young K, Mostov KE. Reduced immunoglobulin A transcytosis associated with immunoglobulin A nephropathy and nasopharyngeal carcinoma. J Biol Chem. 2011;286:44921-5.
32. Robinson JK, Blanchard TG, Levine AD, Emancipator SN, Lamm ME. A mucosal IgA-mediated excretory immune system in vivo. J Immunol. 2001;166:3688-92.
33. Hase K, Kawano K, Nochi T, et al. Uptake through glycoprotein 2 of FimH(+) bacteria by M cells initiates mucosal immune response. Nature. 2009;462:226-30.
34. Krautzberger AM, Kosiol B, Scholze M, Schrewe H. Expression of vasorin (Vasn) during embryonic development of the mouse. Gene Expr Patterns. 2012;12:167-71.
35. Moon PG, Lee JE, You S, et al. Proteomic analysis of urinary exosomes from patients of early IgA nephropathy and thin basement membrane nephropathy. Proteomics. 2011;11:2459-75.
36. Ranieri E, Gesualdo L, Petrarulo F, Schena FP. Urinary IL-6/EGF ratio: a useful prognostic marker for the progression of renal damage in IgA nephropathy. Kidney Int. 1996;50:1990-2001.
37. Torres DD, Rossini M, Manno C, et al. The ratio of epidermal growth factor to monocyte chemotactic peptide-1 in the urine predicts renal prognosis in IgA nephropathy. Kidney Int. 2008;73:327-33.
38. Segers I, Adriaenssens T, Smitz J. Expression patterns of poliovirus receptor, erythrocyte protein band 4.1-like 3, regulator of g-protein signaling 11, and oxytocin receptor in mouse ovarian cells during follicle growth and early luteinization in vitro and in vivo. Biol Reprod. 2012;86:1-11.
39. Bakun M, Niemczyk M, Domanski D, et al. Urine proteome of autosomal dominant polycystic kidney disease patients. Clin Proteomics. 2012;9:13.
40. Redies C, Heyder J, Kohoutek T, Staes K, Van RF. Expression of protocadherin-1 (Pcdh1) during mouse development. Dev Dyn. 2008;237:2496-505.
41. Ciani L, Patel A, Allen ND, ffrench-Constant C. Mice lacking the giant protocadherin mFAT1 exhibit renal slit junction abnormalities and a partially penetrant cyclopia and anophthalmia phenotype. Mol Cell Biol. 2003;23:3575-82.
42. Zheng F, Kundu GC, Zhang Z, Ward J, DeMayo F, Mukherjee AB. Uteroglobin is essential in preventing immunoglobulin A nephropathy in mice. Nat Med. 1999;5:1018-25.
43. Kim YS, Kang D, Kwon DY, et al. Uteroglobin gene polymorphisms affect the progression of immunoglobulin A nephropathy by modulating the level of uteroglobin expression. Pharmacogenetics. 2001;11:299-305.
44. Zhang Z, Kundu GC, Zheng F, et al. Insight into the physiological function(s) of uteroglobin by gene-knockout and antisense-transgenic approaches. Ann N Y Acad Sci. 2000;923:210-33.
45. Coppo R, Chiesa M, Cirina P, Peruzzi L, Amore A. In human IgA nephropathy uteroglobin does not play the role inferred from transgenic mice. Am J Kidney Dis. 2002;40:495-503.
46. Yong D, QingQing W, Hua L, et al. Association of uteroglobin G38A polymorphism with IgA nephropathy: a meta-analysis. Am J Kidney Dis. 2006;48:1-7.
47. Sun AL, Deng JT, Guan GJ, et al. Dipeptidyl peptidase- IV is a potential molecular biomarker in diabetic kidney disease. Diab Vasc Dis Res. 2012;9:301-8.
48. von WK, Reichetzeder C, Hocher B. Physiology and pathophysiology of incretins in the kidney. Curr Opin Nephrol Hypertens. 2014;23:54-60.
49. Mitic B, Lazarevic G, Vlahovic P, Rajic M, Stefanovic V. Diagnostic value of the aminopeptidase N, N-acetylbeta- D-glucosaminidase and dipeptidylpeptidase IV in evaluating tubular dysfunction in patients with glomerulopathies. Ren Fail. 2008;30:896-903.
50. Adachi J, Kumar C, Zhang Y, Olsen JV, Mann M. The human urinary proteome contains more than 1500 proteins, including a large proportion of membrane proteins. Genome Biol. 2006;7:R80.
51. Rao PV, Lu X, Standley M, et al. Proteomic identification of urinary biomarkers of diabetic nephropathy. Diabetes Care. 2007;30:629-37.
52. Oda T, Tamura K, Yoshizawa N, et al. Elevated urinary plasmin activity resistant to alpha2-antiplasmin in acute poststreptococcal glomerulonephritis. Nephrol Dial Transplant. 2008;23:2254-9.
53. Muda AO, Feriozzi S, Rahimi S, Faraggiana T. Spatial arrangement of IgA and C3 as a prognostic indicator of IgA nephropathy. J Pathol. 1995;177:201-8.
54. Giannakakis K, Feriozzi S, Perez M, Faraggiana T, Muda AO. Aberrantly glycosylated IgA1 in glomerular immune deposits of IgA nephropathy. J Am Soc Nephrol. 2007;18:3139-46.
55. Barratt J, Smith AC, Molyneux K, Feehally J. Immunopathogenesis of IgAN. Semin Immunopathol. 2007;29:427-43.
56. Ortega LM, Fornoni A. Role of cytokines in the pathogenesis of acute and chronic kidney disease, glomerulonephritis, and end-stage kidney disease. Int J Interferon Cytokine Mediator Res. 2010;2:49-62.