Diagnostic value of the aminopeptidase N, N-acetyl-β-D-glucosaminidase and dipeptidylpeptidase IV in evaluating tubular dysfunction in patients with glomerulopathies

Renal Failure

Volumn 30, Issue 9, 2008, Pages 896-903

  Mitic, Branka ^a   Lazarevic, Gordana ^b   Vlahovic, Predrag ^a   Rajic, Milena ^a   Stefanovic, Vladisav ^a  

^a Faculty of Medicine   (Serbia)

^b Clinical Center   (Serbia)

Author keywords

Aminopeptidase N; Dipeptidylpeptidase IV; Glomerulonephritis; N acetil D glucosaminidase; Plasma cell glycoprotein 1

Indexed keywords

AMINOPEPTIDASE; DIPEPTIDYL PEPTIDASE IV; GLYCOPROTEIN IB; IMMUNOGLOBULIN A; MICROSOMAL AMINOPEPTIDASE; N ACETYL BETA GLUCOSAMINIDASE;

ADULT; ARTICLE; CONTROLLED STUDY; DIABETIC NEPHROPATHY; FEMALE; GLOMERULOPATHY; HUMAN; LUPUS ERYTHEMATOSUS NEPHRITIS; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; PRIORITY JOURNAL; PROTEIN DETERMINATION; TUBULAR DYSFUNCTION; URINARY EXCRETION;

ACETYLGLUCOSAMINIDASE; ADULT; AGED; ANTIGENS, CD13; ANTIGENS, CD26; BIOLOGICAL MARKERS; DIABETIC NEPHROPATHIES; FEMALE; GLOMERULONEPHRITIS; HUMANS; KIDNEY FUNCTION TESTS; KIDNEY TUBULES; MALE; MIDDLE AGED; PHOSPHORIC DIESTER HYDROLASES; PREDICTIVE VALUE OF TESTS; PYROPHOSPHATASES;

EID: 54249132506     PISSN: 0886022X     EISSN: 15256049     Source Type: Journal    
DOI: 10.1080/08860220802359048     Document Type: Article

References (28)

1. Cameron JS. Tubular and interstitial factors in the progression of glomerulonephritis. Pediatr. Nephrol. 1992;6:291-303.
2. Stefanovic V, Antic S. Plasma cell membrane glycoprotein 1 (PC-1): A marker of insulin resistance in obesity, uremia, and diabetes mellitus. Clin. Lab. 2004;50:271-278.
3. Dong H, Maddux BA, Altomonte J, Meseck M, Accili D, Terkeltaub R, Johnson K, Youngren JF, Goldfine ID, Meseck M, Accili D, Terkeltaub R, Johnson K, Youngren JF, Goldfine ID. Increased hepatic levels of the insulin receptor inhibitor, PC-1/ENPP1, induce insulin resistance and glucose intolerance. Diabetes. 2005;54:367-372.
4. Maddux BA, Sbraccia P, Kumakura S, Sasson S, Youngren J, Fisher A, Spencer S, Grupe A, Henzel W, Stewart TA. Membrane glycoprotein PC-1 and insulin resistance in non-insulin dependent diabetes mellitus. Nature. 1995;373:448-451.
5. Kumakura S, Maddux BA, Sung CK. Overexpression of membrane glycoprotein PC-1 can influence insulin action at a postreceptor cite. J. Cell. Biochem. 1998;68:366-377.
6. Haugen HF, Skrede S. Nucleotide pyrophosphatase and phosphodiesterase I. Organ distribution and activities in body fluids. Clin. Chem. 1977;23:1531-1537.
7. Le Hir M, Dubach UC, Angielski S. Localization of nucleotide pyrophosphatase in the rat kidney. Histochemistry. 1986;86:207-210.
8. Stefanovic V, Vlahovic P, Ardaillou R. Characterization and control of expression of cell surface alkaline phosphodiesterase I activity in rat mesangial glomerular cells. Renal Physiol. Biochem. 1995;18:18-20.
9. Stefanovic V, Rajic M, Antic S, Mitić-Zlatković M, Stojiljković S, Ivić MA, Vlahović P. Urinary PC-1 activity in patients with type 1 diabetes mellitus. Ann. Clin. Biochem. 2003;40:235-238.
10. Stefanovic V, Vlahovic P, Ardaillou N, Ronco P, Ardaillou R. Cell surface aminopeptidase A and N activities in human glomerular epithelial cells. Kidney Int. 1992;41:1571-1580.
11. Dixon J, Kaklamanis L, Turley H, Hickson ID, Leek RD, Harris AL, Gatter KC. Expression of aminopeptidase-n (CD 13) in normal tissues and malignant neoplasms of epithelial and lymphoid origin. J. Clin. Pathol. 1994;47:43-47.
12. Stefanovic V, Vlahovic P, Ardaillou N, Ronco P, Nivez MP, Ardaillou R. Characterisation and control of expression of cell surface aminopeptidase N activity in human mesangial glomerular cells. Cell. Physiol. Biochem. 1992;2:57-68.
13. Holdt-Lehmann B, Lehmann A, Korten G, Nagel H, Nizze H, Schuff-Werner P. Diagnostic value of urinary alanine aminopeptidase and N-acetyl-beta-D- glucosaminidase in comparison to alpha 1-microglobulin as a marker in evaluating tubular dysfunction in glomerulonephritis patients. Clin Chim Acta. 2000;297:93-102.
14. Jones AP, Lock S, Griffiths KD. Urinary N-acetyl-β-D-glucosaminidase activity in type 1 diabetes mellitus. Ann Clin Biochem. 1995;32:58-62.
15. 2-microglobulin levels and urinary N-acetyl-β-D- glucosaminidase enzyme activities in early diagnosis of non-insulin dependent diabetes mellitus nephropathy. Diabetes Res. 1994;26:101-107.
16. Chatelet F, Brianti E, Ronco P, Roland J, Verroust P. Ultrastructural localization by monoclonal antibodies of brush border antigens expressed by glomeruli. I. Renal distribution. Am J Pathol. 1986;122:500-511.
17. Green BD, Flatt PR, Bailey CJ. Inhibition of dipeptidylpeptidase IV activity as a therapy of type 2 diabetes. Expert Opin Emerg Drugs. 2006;11:525-539.
18. Haugen HF, Skrede S. Nucleotide pyrophosphatase and phosphodiesterase I. Organ distribution and activities in body fluids. Clin Chem. 1977;23:1531-1537.
19. Horak E, Hopfer SM, Sunderman W. Spectrophotometric assay for urinary N-acetyl-β-D-glucosaminidase activity. Clin Chem. 1981;27:1180-1185.
20. Stefanovic V, Ardaillou N, Vlahovic P, Placier S, Ronco P, Ardaillou R. Interferon-γ induces dipeptidylpeptidase IV expression in human glomerular epithelial cells. Immunology. 1993;80:465-470.
21. Remuzzi G, Bertani T. Pathophysiology of progressive nephropathies. N Engl J Med. 1998;339:1448-1456.
22. Idris I, Donnelly R. Dipeptidyl peptidase-IV inhibitors: A major new class of oral antidiabetic drug. Diabetes Obes Metab. 2007;9:153-165.
23. Stefanovic V, Antic S, Mitic-Zlatkovic M, Vlahovic P. Reversal of increased lymphocyte PC-1 activity in patients with type 2 diabetes treated with metformin. Diabetes Metab Res Rev. 1999;15:400-404.
24. Bazzi C, Petrini C, Rizza V, Arrigo G, Napodano P, Paparella M, D'Amico G. Urinary N-acetyl-beta-glucosaminidase excretion is a marker of tubular cell dysfunction and a predictor of outcome in primary glomerulonephritis. Nephrol Dial Transpant. 2002;17:1890-1896.
25. Rajic M, Ilic S, Vlajkovic M, Antic S, Velickovic L, Stefanovic V. Radionuclide staging of renal function in type 1 diabetes mellitus. Ren Fail. 2007;29:685-691.
26. Weitgasser R, Schnoell F, Gappmayer B, Kartnig I. Prospective evaluation of urinary N-acetyl-beta-D-glucosaminidase with respect to macrovascular disease in elderly type 2 diabetic patients. Diabetes Care. 1999;22:1882-1886.
27. Navarro JF, Mora C, Muros M, Maca M, Garca J. Effects of pentoxifylline administration on urinary N-acetyl-beta-glucosaminidase excretion in type 2 diabetic patients: A short-term, prospective, randomized study. Am J Kidney Dis. 2003;42:264-270.
28. Hsiao PH, Tsai WS, Tsai WY, Lee JS, Tsau YK, Chen CH. Urinary N-acetyl-beta-D-glucosaminidase activity in children with insulin-dependent diabetes mellitus. Am J Nephrol. 1996;16:300-303.