Urinary IL-6/EGF ratio: A useful prognostic marker for the progression of renal damage in IgA nephropathy

Kidney International

Volumn 50, Issue 6, 1996, Pages 1990-2001

  Ranieri, Elena ^b   Gesualdo, Loreto ^b   Petrarulo, Francesco ^b   Schena, Francesco P ^a  

^a UNIVERSITY OF BARI   (Italy)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR; INTERLEUKIN 6;

ARTICLE; CLINICAL ARTICLE; FEMALE; HUMAN; HUMAN TISSUE; IMMUNOGLOBULIN A NEPHROPATHY; KIDNEY INJURY; MALE; PRIORITY JOURNAL; PROGNOSIS;

EID: 0029958465     PISSN: 00852538     EISSN: None     Source Type: Journal    
DOI: 10.1038/ki.1996.521     Document Type: Article

References (58)

1. SCHENA FP: A retrospective analysis of the natural history of primary IgA nephropathy worldwide. Am J Med 89:209-215, 1990
2. LEE SMK, RAO MV, FRANKLIN WA: IgA nephropathy: Morphologic predictors of progressive renal disease. Human Pathol 13:314-322, 1982
3. D'AMICO G: Role of infiltration of leukocytes in glomerular diseases. Nephrol Dial Transplant 3:596-600, 1988
4. ONG ACM, FINE LG: Tubular derived growth factors and cytokines in the pathogenesis of tubulointerstitial fibrosis: Implications for human renal disease progression. Am J Nephrol 23:205-209, 1994
5. FINE LG, ONG ACM, TORMAN JT: Mechanism of tubulo-interstitial injury in progressive renal diseases. Eur J Clin Invest 23:259-265, 1993
6. ONG ACM, FINE LG: Tubular-derived cytokines and human renal disease progression. Nephrol Dial Transplant 9:471-472, 1994
7. EMANCIPATOR SN, SEDOR JR: Cytokines in renal disease, in Cytokines in Health and Disease: Physiology and Pathophysiolopy (vol 25), edited by REMICK DG, KUNKEL SL, New York, Marcel Dekker, 1992, pp 467-488
8. ABDOUD HE: Growth factors in glomerulonephritis. Kidney Int 43: 252-267, 1993
9. GESUALDO L, DI PAOLO S, RANIERI E, SCHENA FP: Growth factors and their receptors in the progression of renal damage. Contrib Nephrol 111:38-44, 1995
10. HORII Y, MURAGUCHI A, IWANO M, MATSUDA T, HIRAYAMA T, YAMADA H, FUJII Y, DOHI K, ISHIKAWA H, OHMOTO Y, YOSHIZAKI K, HIRANO T, KISHIMOTO T: Involvement of IL-6 in mesangial proliferative glomerulonephritis. J Immunol 143:3949-3956, 1989
11. FUKATSU A, MATSUO S, TAMAI H, SAKAMOTO N, MATSUDA T, HIRANO T: Distribution of interleukin-6 in normal and diseased human kidney. Lab Invest 65:61-66, 1991
12. FUKATSU A, MATSUO S, YUZAWA Y, MIYAI H, FUTENMA A, KATO K: Expression of interleukin 6 and major histocompatibility complex molecules in tubular epithelial cells of diseased human kidneys. Lab Invest 69:5867-5874, 1993
13. OHTA K, TAKANO N, SENO A, YACHIE A, MIYAWAKI T, YOKOYAMA H, TOMOSUGI N, KATO E, TANIGUCHI N: Detection and clinical usefulness of urinary interleukin-6 in the diseases of kidney and urinary tract. Clin Nephrol 38:185-189, 1992
14. IWANO M, DOHI K, HIRATA E, KURUMANTANI N, HORII Y, SHIIKI H, FUKATSU A, MATSUDA T, HIRANO T, ISHIKAWA H: Urinary levels of IL-6 in patients with active lupus nephritis. Clin Nephrol 40:16-21, 1993
15. TOMINO Y, FUNABIKI K, OHMURO H, SHIMIZU M, YOKOYAMA K, SHIRATO I, SHIRAI T, TAKAHASHI M, KOIDE H: Urinary levels of interleukin-6 and disease activity in patients with IgA nephropathy. Am J Nephrol 11:459-464, 1991
16. HUMES HD, CIESLINSKI DA, COIMBRA TM, MESSANA JM, GALVAO C: Epidermal growth factor enhances renal tubule regeneration and repair and accelerates recovery of renal function in post-ischemic renal failure. J Clin Invest 84:1757-1761, 1989
17. COIMBRA TM, CIESLINSKI DA, HUMES HD: Epidermal growth factor accelerates renal repair in mercuric chloride nephrototoxicity. Am J Physiol 259:F438-F443, 1990
18. NORMAN J, TSAU YK, BACAY A, FINE LG: Epidermal growth factor (EGF) accelerates recovery from ischemic acute tubular necrosis: Role of the EGF-receptor. Clin Sci 78:445-449, 1990
19. COLEMAN D, RUEF C: Interleukin 6: An autocrine regulator of mesangial cell growth. Kidney Int 41:604-611, 1992
20. FRANK J, ENGLER-BLUM G, RODEMANN HP, MÜLLER GA: Human tubular cells as a cytokine source: PDGF-B, GM-CSF and IL-6 mRNA expression in vitro. Exp Nephrol 1:26-35, 1993
21. SAFIRSTEIN R, PRICE PM, SAGGI S, HARRIS RC: Changes in gene expression after temporary renal ischemia. Kidney Int 37:1515-152, 1990
22. STORCH S, SAGGI S, MEGYESI J, PRICE PM, SAFIRSTEIN R: Uretral obstruction decreases renal prepro-epidermal growth factor and Tamm-Horsfall expression. Kidney Int 42:89-94, 1992
23. WALTON O, BUTTYAN R, GARCIA-MONTES E, OLSSON CA, HENSLE TW, SAWCZUK IS: Renal growth factor expression during the early phase of experimental hydronephrosis. J Urol 148:510-514, 1992
24. GESUALDO L, DI PAOLO S, CALABRÒ A, MILANI S, MAIORANO E, RANIERI E, PANNARALE G, SCHENA FP: Expression of epidermal growth factor and its receptor in normal and diseased human kidney. An immunohistochemical and in situ hybridization study. Kidney Int 49:656-665, 1996
25. TAIRA T, YOSHIMURA A, IIZUKA K, IWASAKI S, IDEURA T, KOSHIKAWA S: Urinary epidermal growth factor levels in patients with acute renal failure. Am J Kidney Dis 22:656-661, 1993
26. NIKOLIC-PATERSON DJ, TESCH GH, LAN HY, NUKII K, FOTI R, ATKINS RC: EGF and EGF-receptor expression in rat anti-Thy-1 mesangial proliferative nephritis. Nephrology 1:83-93, 1995
27. NAKOPOULOU L, STEFANAKI K, BOLETIS J, PAPADAKIS J, KOSTAKIS A, VOSNIDES GR, ZEIS PM: Immunohistochemical study of epidermal growth factor receptor (EGFR) in various types of renal injury. Nephrol Dial Transplant 9:764 -769, 1994
28. CHOMCZYNSKI P, SACCHI N: Single step method of RNA isolation by acid guanidinium thiocyanate-phenol chloroform extraction. Anal Biochem 162:156-159, 1987
29. SAMBROOK J, FRITSCH EF, MANIATIS T: Molecular Cloning: A Laboratory Manual Cold Spring Harbor, Cold Spring Harbor Laboratory Press, 1989
30. MILANI S, HERBST H, SCHUPPAN D, HAHN EG, STEIN H: In situ hybridization for pro-collagen types I, III and IV mRNA in normal and fibrotic rat liver: Evidence for predominant expression in non parenchymal liver cells. Hepatology 10:84-92, 1989
31. GESUALDO L, DI PAOLO S, MILANI S, PINZANI M, GRAPPONE C, RANIERI E, PANNARALE G, SCHENA FP: Expression of platelet-derived growth factor receptors in normal and diseased human kidney. J Clin Invest 94:50-58, 1994
32. SABOLIC I, VALENTI G, VERBAVATZ JM, VAN HOEK AN, VERKMAN AS, ADSIELLO DA, BROWN D: Localization of CHIP28 water channel in rat kidney. Am J Physiol 263:C1225-C1233, 1992
33. FOGAZZI GB, BANFI G, PONTICELLI C: Retrodiffusion of Tamm-Horsfall protein (THP) into the glomerular Bowman's space (GBS): A study by immunofluorescence (IF) on renal biopsies. (abstract) Nephrol Dial Transplant 9:891A, 1994
34. HIRANO T, AKIRA S, TAGA T, KISHIMOTO T: Biological and clinical aspects of interleukin 6. Immunol Today 11:443-449, 1990
35. LE J, VILCEK J: Biology of disease. Interleukin 6: A multifunctional cytokine regulating immune reaction and the acute phase proteine response. Lab Invest 61:588-598, 1989
36. MURAGUCHI A, HIRANO T, TANG B, MATSUDA T, HORII Y, NAKAJIMA K, KISHIMOTO T: The essential role of B cell stimulatory factor 2 (BSF-2/IL-6) for the terminal differentiation of B cells. J Exp Med 167:332-344, 1988
37. BAUER J, HERRMANN F: Interleukin-6 in clinical medicine. Ann Hematol 62:203-210, 1991
38. BHARDWAJ N, SANTHANAM U, LAU LL, TATTER SB, GHRAYEB J, RIVELS M, STEINMANN RM, SEHGAL PB, MAY LT: IL-6/IFNβ2 in synovial effusions of patients with rheumatoid arthritis and other arthritides. Blood 73:1279-1284, 1989
39. BRANDT SJ, BODINE DM, DUNBAR CE, NIENHUIS AW: Dysregulated interleukin-6 expression produces a syndrome resembling Castelman's disease in mice. J Clin Invest 86:592-599, 1990
40. BREEN EC, REZAI AR, NAKAJIMA K, BEALL, GN, MITSUYASU T, HIRANO RT, KISHIMOTO T, MARTINEZ-MAZA O: Infection with HIV is associated with elevated IL-6 levels and production. J Immunol 144:480-484, 1990
41. MOSHAGE HJ, ROELOFS HNJ, VAN PELT JF, HAZENBERG BPC, VAN LEEWEN MA, LIMBURG PC, AARDEN LA, YAP SH: The effect of interleukin-1, interleukin-6 and its interrelationship on the synthesis of serum amyloid A and C-reactive protein in primary cultures of adult human hepatocytes. Biochem Biophys Res Comm 155:112-117, 1988
42. JOURDAN M, BATAILLE R, SEGUIN J, ZHANG XG, CHAPTAL PA, KLEIN B: Constitutive production of interleukin-6 and immunologie features in cardiac myxoma. Arthritis Rheum 33:398-403, 1990
43. RALL LB, SCOTT J, BELL GI, CRAWFORD RJ, PENSHOW JD, COGHLAND JP: Mouse prepro-epidermal growth factor syntesis by the kidney and other tissue. Nature 313:228-231, 1985
44. SALIDO EC, YEN PH, SHAPIRO LJ, FISHER DA, BARAJAS L: In situ hybridization of pre-pro epidermal growth factor mRNA in the mouse kidney. Am J Physiol 256:F632-F638, 1989
45. SALIDO EC, LAKSHMANAN J, FISHER DA, SHAPIRO LJ, BARAJAS L: Expression of epidermal growth factor in the rat kidneys. An immunocytochemical and in situ hybridization study. Histochemistiy 96:65-72, 1991
46. CARPENTER G, COHEN S: Epidermal growth factor. Annu Rev Biochem 48:193-216, 1979
47. FISHER DA, SALIDO EC, BARAJAS L: Epidermal growth factor and the kidney. Annu Rev Physiol 51:67-80, 1989
48. HARRIS RC: Potential Physiologic roles for epidermal growth factor in the kidney. Am J Kidney Dis 17:627-630, 1991
49. HARRIS RC, HOOVER RL, JACOBSON HR: Evidence for glomerular actions of epidermal growth factor in the rat. J Clin Invest 82:1028-1032, 1988
50. HARRIS RC, DANIEL TO: Epidermal growth factor binding stimulation of phosphorylation and inhibition of gluconeogenesis in rat proximal tubule. J Cell Physiol 139:383-387, 1989
51. HARRIS RC: Response of rat inner medullary collecting duct to epidermal growth factor. Am J Physiol 256:F1117-F1123, 1989
52. FISHER DA, LAKSHMANAN J: Metabolism and effects of epidermal growth factor and related growth factors in mammals. Endrocrinol Rev 11:418-422, 1990
53. VEHASKARI VM, HERING-SMITH KS, MOSKOWITZ DW, WEINER ID, HAMM LL: Effect of epidermal growth factor on sodium transport in the cortical collecting tubule. Am J Physiol 256:F803-F809, 1989
54. ENGEL J: EGF-like domains in extracellular matrix proteins: Localized signal for growth and differentation? FEBS Lett 251:1-7, 1989
55. GOODYER PR, MULLIGAN L, GOODYER CG: Expression of growth-related genes in human fetal kidney. Am J Kidney Dis 17:608-610, 1991
56. RAASVELD MHM, WEENING JJ, KERST JM, SURACHNO S, TEN BERGE RJM: Local production of interleukin-6 during rejection in human renal allografts. Nephrol Dial Transplant 8:75-78, 1993
57. DUNCAN MR, BERMAN B: Stimulation of collagen and glucosaminoglycan production in cultured human adult dermal fibroblast by recombinant human interleukin 6. J Invest Dermatol 97:686-692, 1991
58. SATO T, ITO A, MORI Y: Interleukin 6 enhances the production of tissue inhibitor of metalloproteinases (TIMP) but not that of matrix metalloproteinases by human fibroblasts. Biochem Biophys Res Commun 170:824-829, 1992